Ubistezin forte solution for injection. (40 mg/10 µg)/ml in cart. 1.7 ml in pack. No. 50

28.10.2019

Before the advent of painkillers, tooth extraction was painful. Even at the beginning of the 20th century, such operations were performed without anesthesia. Nowadays dentistry uses many methods and a variety of drugs that make it possible to remove teeth absolutely painlessly. This helps to avoid discomfort and complications. After all, doctors choose drugs individually, depending on the patient’s health condition and the characteristics of the surgical intervention. An anesthetic is used for tooth extraction, treatment of pulpitis, periodontitis, implantation and other dental procedures.

Why is pain relief performed in dentistry?

Before tooth extraction, anesthesia is required, as this operation is very painful. These sensations can trigger a heart attack or put the patient into shock. Therefore, such manipulations are now carried out under anesthesia. Most often, local anesthesia is used. The injected drug blocks the transmission of nerve impulses from the diseased tooth to the brain. The sensitivity of the gums and surrounding tissues is greatly reduced. Therefore, the tooth is removed painlessly.

Many patients do not visit the dentist on time precisely because they are afraid of pain. They drown out unpleasant sensations with pills, which often leads to serious complications. But, the use of painkillers during tooth extraction allows treatment to be carried out without discomfort for the patient.

Ubistezin

Ubistezin is a German drug that is produced. It contains the local anesthetic articaine and the hormone epinephrine (adrenaline), which has a vasoconstrictor effect. Vasoconstriction ensures a low degree of penetration of the drug into the blood and maximum effect at the site of use.

The drug has 2 release forms: with an epinephrine concentration of 1:200000 and 1:100000. The analgesic effect occurs within 1-3 minutes after administration. The duration of action is at least 75 minutes.

The drug is used only for anesthesia in dentistry (infiltration and conduction). It should not be administered intravenously or used in areas of inflammation.

Septanest

Septanest is an anesthetic that has been used in medical practice for quite some time. In addition to articaine and epinephrine, it contains auxiliary substances, which often cause complications of anesthesia in dentistry such as allergic reactions of patients. The drug is available in two dosage forms: with an epinephrine content of 1:100,000 and 1:200,000.

The effect of the drug appears after 1-3 minutes. Its duration is at least 45 minutes. It has good tissue tolerance and has a moderate vasoconstrictor effect.

Scandonest

What anesthesia in dentistry is suitable for patients with diabetes, thyroid diseases, an increased tendency to allergic reactions and patients with bronchial asthma? Scandonest is a drug that does not contain vasoconstrictor components or preservatives. Therefore, it is suitable for all patients at risk. For some, it is used with caution (during pregnancy, diseases of the liver, kidneys and cardiovascular system).

The anesthetic is produced on the basis of 3% mepivacaine. It provides fast, long-lasting and strong pain relief. Suitable for all types of local anesthesia.

Ultracaine

Ultracaine

– this is the best anesthesia in dentistry during pregnancy and for many diseases. It is based on articaine and is available in three forms: with a concentration of epinephrine 1:100000, 1:200000 and completely without epinephrine. The drug contains almost no preservatives. Lasts on average 2-3 hours. According to reviews from dentists and patients, ultracaine is the most potent among its analogues.

The cost of a carpule of any of the listed medications is approximately 30-50 rubles.
This article is for informational purposes only, please consult your doctor for details!

Types of anesthesia before tooth extraction

In most cases, local anesthesia is sufficient for any dental procedures. Typically, this is one or more injections into the gums. Some clinics perform three-stage anesthesia, which completely eliminates pain. In this case, an anesthetic gel is first applied, then a short injection is given, and after some time a sufficient dose of anesthetic is administered. Sometimes it also becomes necessary to perform a similar operation under general anesthesia. What anesthesia for tooth extraction is required in each specific case is determined by the doctor in accordance with individual characteristics.

Most often, local anesthesia is sufficient. Such anesthesia relieves the patient 100% of pain. Only tactile sensitivity is preserved, which can also cause discomfort, but not severe. There are several types of local anesthesia.

  1. Application anesthesia relieves pain only with superficial intervention. It is usually used before an injection to make insertion of the needle painless. Sometimes it is indicated when removing baby teeth in children. This anesthesia is carried out using a gel or spray based on lidocaine or benzocaine. They are applied to the gums.
  2. Infiltration anesthesia is the most common method. In this case, pain relief during tooth extraction is administered by injection. Usually you need 2-3 injections on one side and the other of the diseased tooth.
  3. Conduction anesthesia involves injecting an anesthetic into the area of ​​the nerve. After this, the entire area innervated by it loses sensitivity. It is usually used only on the lower jaw.
  4. Trunk anesthesia is used in serious cases or when the patient is hypersensitive. In this case, the medicine is injected into the base of the skull.

In addition, sometimes a method such as sedation is also used. This is the administration of intramuscular or intravenous sedatives. They calm the patient, increase the pain threshold, and relax.

Ubistezin forte

Adults

For uncomplicated extraction of teeth in the upper jaw in the absence of inflammation, 1.7 ml of the drug (for each tooth) is usually injected into the submucosa in the area of ​​the transitional fold on the vestibular side.

In some cases, additional administration of 1 to 1.7 ml of the drug may be required to achieve complete anesthesia. In most cases, there is no need to perform painful injections on the palatal side. For anesthesia for palatal incisions and suturing to create a palatal depot, about 0.1 ml of the drug per injection is required. When removing several adjacent teeth, the number of injections can usually be limited. In the case of removal of mandibular premolars in the absence of inflammation, mandibular anesthesia can be dispensed with, because infiltration anesthesia provided by an injection of 1.7 ml per tooth is usually sufficient. If this way failed to achieve the desired effect, an additional injection of 1-1.7 ml of the drug should be performed into the submucosa in the area of ​​the transitional fold of the mandible on the vestibular side. If in this case it was not possible to achieve complete anesthesia, it is necessary to block the mandibular nerve. To prepare a tooth cavity for filling or treatment for the crown of any tooth, with the exception of the lower molars, administration of the drug in a dose of 0.5 to 1.7 ml for each tooth according to the type of infiltration anesthesia from the vestibular side is indicated. The exact amount depends on the desired depth and duration of the procedure.

When performing one treatment procedure, adults can be administered up to 7 mg of articaine per 1 kg of body weight. The duration of intrapulpal anesthesia is at least 75 minutes, the duration of soft tissue anesthesia is from 120 to 240 minutes. Elderly patients

An increase in the concentration of the drug in the blood plasma may be caused by a decrease in metabolic processes and a decrease in the volume of distribution.
In particular, the risk of drug accumulation after repeated administration increases. A dose reduction is required for heart and liver diseases. Patents with liver failure
Articaine is metabolized by the liver.
Dose reduction may be necessary to achieve sufficient depth of anesthesia and systemic accumulation. Patients with renal failure
Articaine and its metabolites are mainly excreted in the urine. Dose reduction may be necessary to achieve sufficient depth of anesthesia and systemic accumulation. A dose reduction is required for angina pectoris, atherosclerosis and other diseases listed in the “With caution” section.

Children (from 4 years to 18 years)

In pediatric patients (over 4 years of age), the dose of the drug is selected depending on the age and body weight of the child. The recommended dose of the drug depends on body weight:

Body mass Recommended dose
articaine/mg/child drug/ml/child
20-<30 10-40 0.25 ml - 1 ml
30-<40 20-80 0.5 ml - 2 ml
40-<45

Do not exceed a dose equivalent to 7 mg articaine/kg body weight! Maximum recommended doses for children:

Body weight (kg) (corresponds to the age groups of children according to ±

growth chart standards)

Maximum permitted dose based on 7 mg/kg body weight
articaine

mg/child

a drug

ml/child

20- <30 140 3,5
30- <40 210 5,25
40- <45 280 7,0
45 — <50 315 7,9
50-<60 350 8,7
60-<70 420 10,5
70 — <80 490 12,2

Due to the fact that articaine diffuses quickly into tissue and bone density is lower in children compared to adults, infiltration anesthesia can be used instead of conduction anesthesia for children.

Preparations for infiltration anesthesia

Anesthesia in dentistry is most often carried out using injection solutions. The most common ones for this are “Lidocaine” or “Novocaine” in ampoules. It is these medications that provide pain relief in all budget clinics. For this, special syringes with a thin needle are used. But recently, new technologies have been increasingly used. For example, private medical centers have switched to carpule anesthesia. Its peculiarity is the use of disposable cartridges with medicine. In addition, the needle for such injections is taken very sharp, which ensures the absence of pain during the injection.

In addition to Novocaine and Lidocaine, articaine and mepivacaine have recently been used in dentistry. There are several drugs based on these substances:

  1. "Ultracaine";
  2. "Scandonest";
  3. "Ubistezin";
  4. "Septanest".

The drug "Novocain" in dentistry

This anesthetic was synthesized at the beginning of the 20th century. And for many years, Novocain in ampoules became the most common means of pain relief during any surgical interventions. This is an inexpensive drug, so it is accessible to everyone; a package costs 30-40 rubles. But recently it has been used less and less due to the high risk of side effects.

The instructions for Novocain warn that after its administration, a drop in blood pressure, dizziness, weakness or allergic reactions may occur. In addition, sometimes it is not very effective, so it is administered together with other drugs. Most often, Novocaine is combined with adrenaline, but this mixture is contraindicated for high blood pressure. The low effectiveness of this drug, as well as the loss of its functions in the presence of purulent inflammation, has led to the fact that it is now used very rarely in dentistry.

Use of the drug "Lidocaine"

This is the most common anesthetic, widely used not only in budget dental clinics, but also in private ones. It is quite effective, completely removing sensitivity for about 1-2 hours. However, it rarely causes side effects. But sometimes intolerance to Lidocaine still occurs. In this case, allergic reactions, a drop in blood pressure, dizziness, weakness, and heart rhythm disturbances occur. Numbness of the lips and tongue often occurs, which can lead to accidental injury.

In order for this drug to work well and not cause negative reactions, it must be administered in the correct dosage. Sometimes it is sold not in ampoules, but in powder, so you need to know how to properly dilute Lidocaine for injection in dentistry. Most often, a 0.5% solution is used, but for conduction anesthesia in difficult cases, 1-2% can be used. The dosage is determined individually according to the severity of the patient's condition.

The drug "Ultracain"

This product is based on the strong anesthetic articaine. Additionally, the drug contains epinephrine. This is an analogue of adrenaline that has a vasoconstrictor effect. It is needed to lengthen the duration of action of the drug. "Ultracaine" is considered a safer and more effective remedy than the previously common "Lidocaine" or "Novocaine".

The instructions note that it has almost no contraindications. It is even used for children and elderly patients. The advantage of the drug is that it begins to act within 10 minutes, and its analgesic effect lasts up to 3.5 hours. The drug is sold in pharmacies at a price of 500 rubles per pack of 10 ampoules.

The most common side effects after Ultracaine are headaches, nausea and muscle twitching, but this is rare. Even less common is a drop in blood pressure or arrhythmia after administration of the drug. Ultracaine is available in several forms, differing in the dosage of the active substance and epinephrine. The most popular is “Ultracain D”, which does not contain additional components, therefore it is less likely to cause side effects.

The drug "Ubistezin"

The price of this painkiller is slightly higher than that of other similar drugs. But, it is widespread in dentistry due to its high efficiency. In addition to articaine, the drug "Ubistezin" includes adrenaline. It provides vasoconstriction at the injection site. Thanks to this, the drug is absorbed slowly and causes fewer side effects. Because of this, its effect lasts longer. Moreover, the effect occurs within 3-5 minutes after the injection, which in some cases is very important. In addition to the general side effects caused by articaine, after an injection carried out in violation of the rules, tissue ischemia or neurological problems may develop.

The price of “Ubistezin” is quite high, since it is mainly sold in large packages. 50 cartridges cost from 1,500 to 2,000 rubles, so they are purchased from dental clinics. This drug is allowed to be used even in pediatric dentistry. Its advantage is the rapid onset of analgesic effect and good tolerability. But, it is contraindicated to use the drug in case of arrhythmia, tachycardia, or the presence of allergic reactions.

Pain relief with Septanest

The drug is produced by a well-known French pharmaceutical company. It has been used in dentistry for a long time, and has already proven its effectiveness. Therefore, in difficult cases or in the absence of contraindications, dentists often choose Septanest. The instructions for use of the drug note that allergic reactions to this drug occur quite often. This can be explained by the presence of a large number of artificial additives. In addition, side effects such as respiratory and cardiac dysfunction often develop.

However, the drug is quite popular. The instructions for use for Septanest allow the drug to be used by children over 4 years of age and pregnant women. Contraindications include only glaucoma, bronchial asthma and heart rhythm disturbances. If necessary, you can use similar anesthetics that also contain articaine: Alfacaine, Brilocaine, Cytokartin, Primacaine.

The drug "Scandonest"

It is an anesthetic based on mepivacaine. It does not contain adrenaline, preservatives or other harmful components. It is used for intolerance to articaine or adrenaline. This drug can be used in the elderly, patients with diabetes, hypertension, bronchial asthma and even pregnant women. In addition to the analgesic effect, mepivacaine has the ability to constrict blood vessels, so additional adrenaline is not required. An analogue of the drug "Scandonest" is the anesthetic "Mepivastezin".

Ubistezin forte solution for injection. (40 mg/10 µg)/ml in cart. 1.7 ml in pack. No. 50

Name

Ubistezin forte solution for injection. (40 mg/10 µg)/ml in cart. 1.7 ml in pack. No. 50

Description

Transparent, colorless liquid without opalescence.

Main active ingredient

Articaine+Epinephrine

Release form

injection

Dosage

(40mg/10mcg)/ml

pharmachologic effect
Pharmacodynamics

Ubistezin Forte contains articaine, which is an amide-type local anesthetic for use in dentistry and provides reversible inhibition of the irritability of fibers of the autonomic nervous system, sensory and motor nerves. Blocking voltage-gated Na+ channels on the nerve fiber sheath is believed to be the mechanism that determines the action of articaine. It is characterized by a rapid onset of anesthesia - a reaction period of 1-3 minutes, a reliable effect with a powerful analgesic effect and good local tolerance. The duration of action of Ubistezin Forte during pulp anesthesia is at least 75 minutes, and during soft tissue anesthesia - from 120 to 240 minutes. At the local level, epinephrine causes constriction of blood vessels, due to which the absorption of articaine slows down. The result is a higher concentration of a given local anesthetic in the area of ​​application over a longer period, as well as a reduced likelihood of harmful side effects on the body as a whole.

Pharmacokinetics

Ubistezin is absorbed quickly and almost completely. The maximum level of articaine in plasma after intraoral injection is achieved in approximately 10-15 minutes. The volume of distribution is 1.67 L/kg, the half-life is approximately 20 minutes, and Tmax is 10-15 minutes. Articaine is 95% bound in blood serum to plasma proteins. Articaine is rapidly hydrolyzed by plasma cholinesterases into articainic acid, which is further metabolized into articainic acid glucuronide. Articaine and its metabolites are excreted mainly in the urine. Epinephrine is rapidly catabolized in the liver and other tissues. The removal of metabolites from the body is carried out renal.

Indications for use

Ubistezin forte is intended for local anesthesia in dentistry (infiltration and conduction anesthesia of nerves) in adults and children over 4 years of age. - surgical actions on the mucous membrane and bone, which require more severe tissue ischemia; — surgical actions on the dental pulp (amputation and extirpation); — removal of teeth with fractures (osteotomy); - long-term surgical interventions; — percutaneous osteosynthesis; — removal of the cyst; — interventions on the mucous membrane and gums; - removal of the apex of the tooth root.

Use during pregnancy and lactation

There is no clinical experience with the use of the drug in pregnant and breastfeeding women. With regard to harmful effects on fetal development, the safe use of topical anesthetics during pregnancy has not been determined. This medication should only be used during pregnancy if the benefits of such use are judged to outweigh the risks. The elimination of articaine and its metabolites from the body in breast milk has not been studied. However, data from preclinical safety studies indicate that the concentration of articaine in breast milk does not reach clinically significant levels. In this regard, nursing mothers should express and remove the first breast milk after anesthesia using articaine.

Precautionary measures

In patients with cholinesterase deficiency, Ubistezin Forte should be prescribed only in cases of special need and under conditions of additional monitoring, since the effect of the drug is likely to be prolonged and may be too strong. Ubistezin forte should be used with extreme caution in the following cases: disorders of the blood coagulation system; detected dysfunction of the liver and kidneys; concomitant use of halogen inhalational anesthetics; history of epilepsy. Taking into account the lowest adrenaline content (0.005 mg/ml), the use of Ubistezin 40 mg/ml + 0.005 mg/ml should be considered instead of Ubistezin forte 40 mg/ml + 0.010 mg/ml in patients with: cardiovascular diseases (for example, heart failure, ischemic heart disease, angina pectoris, history of myocardial infarction, cardiac arrhythmias, arterial hypertension); atherosclerosis; cerebrovascular accidents, history of stroke; chronic bronchitis, emphysema; diabetes mellitus; severe anxiety. It is not recommended to administer Ubistezin Forte into an area of ​​inflammation (infection) due to increased absorption of the drug and a decrease in its effectiveness. Before using this drug, it is necessary to collect an anamnesis from the patient, obtain information about medications taken, concomitant treatments, and maintain vocal contact with the patient. If there is a risk of allergy, a test dose of the drug (5-10% of the total dose) should be administered first. In order to avoid adverse events, the following must be considered: choose the lowest possible dose; Before administration, aspirate in two stages (to avoid unintentional intravascular injection). It is recommended to refrain from eating until the end of the anesthesia. This medicinal product contains sodium sulfite (E221), which in rare cases may cause severe hypersensitivity reactions and bronchospasm. This drug contains less than 1 mmol of sodium (23 mg) per dose, which means it is practically a “sodium-free” drug.

Interaction with other drugs

The sympathomimetic effect of epinephrine may be enhanced by concomitant use of monoamine oxidase (MAO) inhibitors or tricyclic antidepressants (see section “Contraindications”). Epinephrine may inhibit the production of insulin by the pancreas and thus reduce the effect of oral antidiabetic medications. Concurrent use of non-cardioselective beta blockers may lead to an increase in blood pressure due to the presence of epinephrine in Ubistezin Forte. Some inhaled analgesics, such as halothane, may increase the sensitivity of the heart to catecholamines and thus cause arrhythmias after use of Ubistezin Forte. During treatment with blood coagulation inhibitors, the tendency to bleeding increases (see also section "Special warnings and precautions for use").

Contraindications

Ubistezin Forte is not approved for use in the following cases: for children under 4 years of age; hypersensitivity to the active substances, sodium sulfite (E221) or any of the excipients. Taking into account the effect of articaine, which is part of Ubistezin forte, this drug cannot be used in the following cases: hypersensitivity to other amide-type local anesthetics; identification of disturbances in the generation and conduction of cardiac impulses (for example, 2nd or 3rd degree AV block, significant bradycardia); acute decompensated heart failure (acute congestive heart failure); severe hypotension; hemorrhagic diathesis - especially for conduction anesthesia of nerves. Taking into account the adrenaline that is part of Ubistezin Forte, this drug cannot be used in the following cases: anesthesia of the terminal nerve branches of the fingers and toes (risk of ischemia); patients with angle-closure glaucoma; patients with hyperthyroidism; patients with paroxysmal tachycardia or atrial fibrillation with a high heart rate; patients with recent myocardial infarction (up to 3-6 months); patients in the first 3 months after coronary artery bypass surgery; patients taking non-cardioselective beta-blockers (eg, propranalol) (risk of hypertensive crisis or significant bradycardia); patients with pheochromocytoma; patients with severe arterial hypertension; concomitant treatment with tricyclic antidepressants or MAO inhibitors, since these active substances may enhance the cardiovascular effects of adrenaline. This interaction may occur within 14 days after discontinuation of MAO inhibitors. Intravenous administration is contraindicated. Ubistezin forte should not be used in patients with bronchial asthma and hypersensitivity to sulfites. In such patients, Ubistezin forte can provoke an acute allergic reaction with anaphylactic symptoms, for example, bronchospasm.

Compound

1 ml of injection solution contains: active ingredients Articaine hydrochloride 40 mg Epinephrine 0.010 mg (equivalent to epinephrine hydrochloride - 0.012 mg) other ingredients Sodium sulfite anhydrous 0.6 mg Sodium chloride Water for injection Hydrochloric acid and sodium hydroxide to adjust the pH value.

Directions for use and doses

The following dosage instructions are used: Use the smallest amount of solution possible that will provide effective pain relief. When removing upper teeth, in most cases, 1.7 ml of Ubistezin Forte per tooth is sufficient; In most cases, there is no need to perform painful palatal injections. In cases of alternate removal of adjacent teeth, it is possible to reduce the number and volume of injections. If it is necessary to make an incision or suture in the palate, a palatal injection is indicated at the rate of 0.1 ml for each puncture. To remove premolars of the lower jaw, in most cases, infiltration anesthesia in a volume of 1.7 ml of Ubistezin Forte per tooth is sufficient; in some cases, repeated buccal injection in a volume of 1 to 1.7 ml is required. In rare cases, a mandibular nerve block may be indicated. To prepare a tooth cavity or tooth stump for a crown, injections of Ubistezin Forte are used in volumes from 0.5 to 1.7 ml per tooth. When treating mandibular molars, a nerve block technique should be used. For all surgical procedures, UBISTESIN Forte should be dosed individually depending on the extent and duration of the operation and patient-related factors. When working with children weighing approximately 20 to 30 kg, doses of 0.25 to 1 ml are sufficient; in cases with children weighing from 30 to 45 kg - from 0.5 to 2 ml. Ubistezin Forte should not be used in children under 4 years of age. In elderly patients, due to weakened metabolic processes and a lower volume of distribution, increased plasma levels of Ubistezin Forte may be observed. The risk of accumulation of Ubistezin Forte increases after repeated applications (for example, repeated injections). A similar effect may result from the deteriorated general condition of the patient, as well as severely deteriorated liver and kidney function (see also section "Special warnings and precautions for use"). For this reason, in all such cases, a lower dose range (minimum amount for sufficient depth of analgesia) is recommended. Similarly, doses should be reduced for patients who already have certain concomitant diseases (bronchial asthma, arteriosclerosis) (see also section "Special warnings and precautions for use"). Maximum Recommended Dosage Adults For healthy adult patients, the maximum dose is 7 mg articaine per kg body weight (500 mg for a 70 kg patient), which is equivalent to 12.5 ml Ubistezin Forte. The maximum dose is 0.175 ml of solution per 1 kg. For children The amount to be injected should be determined by the age and weight of the child and the extent of the operation. Do not exceed a dose equivalent to 7 mg of articaine per 1 kg of body weight (0.175 ml of Ubistezin Forte / kg). For shorter procedures and/or for those situations where control of bleeding in the surgical area is not important, Ubistezin is also used and may be more suitable. Method of administration For injection/administration through the oral mucosa. FOR USE IN DENTAL ANESTHESIA ONLY. To avoid intravascular injection, careful aspiration control should always be ensured in at least two planes (rotating the needle 180°), although a negative aspiration result does not guarantee the complete exclusion of involuntary and undetected intravascular injection. The injection rate should not exceed 0.5 ml per 15 seconds, that is, 1 ampoule per minute. In most cases, serious general reactions of the body as a result of accidental intravascular injection can be avoided due to the injection technique - after aspiration, slowly inject 0.1-0.2 ml of the drug and slowly use the rest - no earlier than 20-30 seconds later. Opened ampoules should not be used on other patients. Leftovers should be thrown away. This medicinal product should not be used if there is cloudiness or discoloration.

Overdose

Adverse effects (indicating abnormally high concentrations of the local anesthetic in the blood) may be observed either immediately, resulting from accidental intravascular injection or abnormal absorption conditions, such as in inflamed or vascularized tissue, or subsequently, as a result of actual overdose after administration of an excessive amount anesthetic solution, and manifest itself as symptoms of dysfunction of the central nervous system and/or cardiovascular system. Symptoms due to the local anesthetic ingredient Articaine Mild central nervous system symptoms include a metallic taste in the mouth, tinnitus, dizziness, nausea, vomiting, restlessness, restlessness, and an initial increase in respiratory rate. More serious symptoms include drowsiness, blackouts, tremors, muscle cramps, clonic seizures, coma, and respiratory paralysis. Severe symptoms from the cardiovascular system are observed in the form of decreased blood pressure, disturbances in the passage of cardiac impulses, bradycardia, and circulatory arrest. Symptoms due to the action of a vasoconstrictor such as epinephrine Cardiovascular symptoms such as a feeling of heat, sweating, increased heart rate, migraine headache, increased blood pressure, angina pectoris, tachycardia, tachyarrhythmia and circulatory arrest. Cross-talk in the clinical picture may result from the simultaneous occurrence of various complications and side effects. Therapy If adverse reactions occur, the use of the local anesthetic should be discontinued. General basic measures Assessment of the state of vital functions (respiration, circulation, nervous system), maintenance/restoration of vital functions of breathing and circulation, oxygen supply, intravenous injections.

Side effect

The following categories are chosen to classify the frequency of side effects: Very common (1/10 or more often). Often (1/100 or more often, less often 1/10). Uncommon (1/1000 or more often, less often 1/100). Rarely (1/10000 or more often, less often 1/1000). Very rare (less than 1/10,000). Unknown (frequency cannot be determined from available data). Immune system disorders Not known: allergic or pseudoallergic hypersensitivity reactions. Such reactions may manifest as swelling or inflammation at the injection site or various manifestations beyond the boundaries of drug administration, for example, redness of the skin, itching, conjunctivitis, rhinitis, swelling of the face (angioedema), upper and/or lower lip, cheeks, vocal cords , pharynx with difficulty breathing, swallowing, urticaria, severe shortness of breath, which can progress to anaphylactic shock. Nervous system disorders Common: paresthesia, hypoesthesia; headache, possibly associated with the action of epinephrine, which is part of the drug. Uncommon: dizziness. Not known: Possible dose-dependent central nervous system reactions (especially at extremely high doses or inadvertent intravascular administration of the drug): restlessness, nervousness, stupor, which at times progresses to loss of consciousness, coma, respiratory distress, which at times progresses to respiratory arrest, chills and muscle twitching, which can progress to generalized seizures. Peripheral nerve damage (eg, facial nerve palsy) and dullness of taste in the oral cavity are not specific adverse effects of articaine. Nevertheless, such reactions are theoretically possible during any dental procedures and occur due to the anatomical features of the area where the drug is administered or a violation of the administration technique. Visual impairment Unknown: temporary visual impairment (blurred image, blindness, double vision) that develops during the injection of local anesthetic into the scalp or very soon after administration. Cardiovascular disorders: Uncommon: tachycardia. Rarely: palpitations, sweating, sudden decrease in blood pressure, loss of consciousness, pale skin. Not known: cardiac arrhythmias, increased blood pressure, hypotension, bradycardia, heart failure and shock (a condition that may be life-threatening). Gastrointestinal disorders Common: nausea, vomiting. General and injection site conditions Not known: Inadvertent intravascular administration may result in the development of ischemic areas at the injection site, which sometimes progresses to tissue necrosis. Due to the sodium metabisulfite content, the drug may cause hypersensitivity reactions, especially in patients with bronchial asthma. Such reactions may include vomiting, diarrhea, wheezing, acute asthma attack, disturbances in consciousness, or shock.

Storage conditions

Keep out of the reach and sight of children. Do not store at temperatures above 25 °C. Store in original packaging to protect from light. Do not use after the expiration date printed on the bottom of the can and cartridges.

Need for general anesthesia

Sometimes it becomes necessary to treat a patient under general anesthesia. This is necessary if the usual painkiller during tooth extraction does not help, for example, with a low pain threshold or fear of dentists. General anesthesia is also used in patients with various psychological or neurological disorders, as well as with an increased gag reflex. When extracting a tooth, this is rarely required, since the procedure is short, but during long-term treatment, complex surgery or complete implantation, general anesthesia is necessary. It uses trichlorethylene, administered through a breathing mask or injection drugs: Ketamine, Propanidide, Hexenal.

Reviews about pain relief in dentistry

Nowadays dental treatment has become much more comfortable than before. Pain is usually not felt even when removed. At the same time, many patients note that they received effective pain relief with the help of regular Lidocaine. But there are also those who cannot tolerate this drug. And those who have been injected with modern anesthetics note that they have a better analgesic effect. There are many positive reviews about the drug "Ultracain", patients note that they do not feel anything even during a complex operation.

Category: Tooth extraction Published by Mister stomatolog

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