Hofitol
Hofitol
® (Chopytol®) is a herbal preparation based on artichoke leaves. Used for stagnation of bile in the gallbladder and bile ducts, diseases of the liver and gallbladder.
Dosage forms of Hofitol
The following dosage forms of Hofitol are registered by official Russian government agencies:
- film-coated tablets, 200 mg
- oral solution
- injection
One tablet contains:
- active ingredient:
field artichoke (
Cynara scolymus L.
) leaf extract dry (aqueous) 200 mg - excipients:
magnesium trisilicate, corn starch, talc, magnesium stearate, gum lac, rosin, gelatin, calcium carbonate, sucrose, dispersed dye, carnauba wax, polysorbate 80.
The composition of 100 ml of oral solution includes:
- active ingredient:
field artichoke (
Cynara scolymus L.
) fresh leaves thick aqueous extract 20 g - excipients:
ethyl alcohol, orange flavor, glycerol, methyl parahydroxybenzoate, propyl parahydroxybenzoate, purified water.
The composition of the solution for intravenous and intramuscular administration (per 5 ml ampoule) includes:
- active ingredient:
field artichoke (
Cynara scolymus L.
) leaves, purified extract 100 mg - excipient:
purified water.
Indications for use of Hofitol
- chronic non-calculous cholecystitis
- chronic hepatitis
- cirrhosis of the liver
- chronic nephritis
- chronic renal failure
- dyskinesia of the biliary tract of the hypokinetic type
Contraindications to the use of Hofitol
- hypersensitivity to the components of the drug
- cholelithiasis
- obstruction (obstruction) of the biliary tract
- acute diseases of the liver, kidneys, biliary and urinary tracts
- severe hepatocellular failure
- sucrase/isomaltase deficiency
- fructose intolerance
- glucose-galactose malabsorption
- children under 6 years of age.
Official instructions for medical use of Hofitol
- Instructions for medical use of the drug Chophytol. Dosage form: film-coated tablets (pdf, 93 Kb)
- Instructions for medical use of the drug Chophytol. Dosage form: oral solution (pdf, 102 Kb)
- Instructions for medical use of the drug Chophytol. Dosage form: solution for intravenous and intramuscular administration (pdf, 780 Kb)
Patient Materials
- Vasilenko V.V. Artichoke - a forgotten vegetable
The GastroScan.ru website contains materials for patients on various aspects of gastroenterology:
- “Advice from doctors” in the “Patients” section of the site
- “Popular gastroenterology” in the “Literature” section
- “Popular gastroenterology” in the “Video” section
Materials for healthcare professionals regarding the use of Hofitol
Articles and abstracts
- Divnich N.S. The use of low-temperature mud applications and hophytol in complex sanatorium-resort treatment of patients with gastrointestinal dyskinesia. Abstract of dissertation. Ph.D., 14.00.51 - rehabilitation medicine, physical therapy. RRC VMIK, Moscow, 2007.
- Shishkina S.V. Diagnosis and correction of gastrointestinal motor function disorders in dysfunctional biliary tract disorders in children. Abstract of dissertation. PhD, 01/14/08 – Pediatrics. RMAPO, Moscow 2013.
- Filimonova T.R. Complex use of electrosleep and hophytol in the treatment of primary chronic gastroduodenitis // Issues of balneology, physiotherapy and therapeutic physical culture. - 2003. - No. 6. - P. 14-16.
- Filimonova T.R. Electrosleep and hofitol in the complex treatment of pre-ulcerative conditions // Experimental and Clinical Gastroenterology. – 2002. – No. 1. – P. 176–177.
- Filimonova T.R., Serebryakov S.N., Orekhova E.M. The use of electrosleep in the rehabilitation treatment of primary chronic gastroduodenitis. Russian Scientific Center for Restorative Medicine and Balneology of the Ministry of Health and Social Development of the Russian Federation.
- Gulyaeva S.F., Martusevich A.K., Pomaskina T.V. Dynamics of the clinical and functional status of patients with acid-dependent pathology when using Nizhne-Ivkinskaya 2K mineral water in treatment.
On the website GastroScan.ru in the “Literature” section there is a subsection “Diseases of the hepatopancreatobiliary system”, containing publications for healthcare professionals on this topic.
Video
Still from video: Minushkin O.N. Reflux gastritis; alternative treatment
On the website GastroScan.ru in the “Video” section there is a subsection “For Doctors”, containing video recordings of reports, lectures, webinars in various areas of gastroenterology for healthcare professionals.
Before starting treatment with Hofitol, you should consult a doctor. Back to section
Hofitol solution for oral administration 120ml No. 1
Name
Hofitol.
Release forms
Solution.
INN
Artichoke leaf extract.
FTG
Choleretic herbal remedy.
Compound
100 ml of solution contains: active ingredients: thick extract of fresh leaves of Field Artichoke (Sulaga Scolymus L.) (ratio of medicinal plant raw materials/thick extract: 15-30/1, extractant: purified water) 20.0 g; excipients: ethyl alcohol (2.800 g), alcohol tincture of orange peel (2.800 g), glycerol (E422) (0.180 g), methyl parahydroxybenzoate (E218) (0.092 g), propyl parahydroxybenzoate (0.046 g), purified water (qs up to 100 ml ) The medicine contains ethyl alcohol 3.23 vol. %.
Description
Dark brown opaque solution with a slight yellowish precipitate. There may be some slight sediment during storage.
Pharmacotherapeutic group
Other drugs used for diseases of the biliary tract. ATX code: A05AX.
Pharmacological properties
Pharmacodynamics The pharmacological effect of the drug is due to the complex of biologically active substances included in the field artichoke. The drug has a choleretic effect and increases diuresis. Pharmacokinetics No data available. Indications for use Traditionally used to alleviate functional digestive disorders and improve the excretory function of the kidneys.
Contraindications
Hypersensitivity to the components of the drug, as well as to plants of the aster family (Asteraceae), cholelithiasis, biliary tract obstruction, acute diseases of the liver, kidneys, biliary and urinary tracts, severe hepatocellular insufficiency.
Pregnancy and breastfeeding
It is possible to use the drug Hofitol during pregnancy and during breastfeeding according to indications.
Directions for use and doses
For oral administration. Adults: 2.5-5.0 ml of solution (1/2-1 teaspoon) with a small amount of water orally 3 times a day before meals or if functional disorders occur. The course of treatment is 2-3 weeks. Children: 0-12 months 0.3-0.5 ml (5-10 drops), 1-5 years 0.5-1 ml (10-20 drops), 6-12 years 2-3 ml (1/2 teaspoon), over 12 years old - 1 teaspoon 3 times a day.
Special instructions and precautions
Alcoholic beverages should be avoided. The drug contains 3.23 vol. % ethanol, that is, 130 mg per single dose (5 ml), which is equal to 3.23 ml of beer, 1.35 ml of wine per dose. Harmful for persons with alcoholism. Pregnant and breastfeeding women, children and high-risk groups such as patients with liver disease and epilepsy should be considered. If symptoms of the disease persist or worsen while taking the drug, you should stop taking the drug and consult a doctor.
Interaction with other drugs
Interactions associated with the presence of ethyl alcohol (0.13 g per teaspoon): drugs that cause a disulfiram-like reaction (feeling of heat, redness of the skin, vomiting, tachycardia): disulfiram, cefamandole, cefoperazone, latamoxef (antibacterial agents - cephalosporins ), chloramphenicol (antibacterial agent), chlorpropamide, glibenclamide, glipizide, tolbutamide (antidiabetic agents, sulfonylurea derivatives), griseofulvin (antifungal agent), nitro-5-imidazole derivatives (metronidazole, ornidazole, tinidazole), ketoconazole, procarbazine (cytostatic agent) ; drugs that inhibit the functions of the central nervous system. If you are taking other medications at the same time, you should consult your doctor.
Side effect
Allergic reactions are possible; with prolonged use of the drug in high doses, diarrhea may develop. If adverse reactions occur, including those not listed in this instruction, you must stop taking the drug and consult a doctor.
Overdose
Side effects may increase. If symptoms of overdose develop, it is recommended to consult a doctor. Treatment is symptomatic. Effect on the ability to drive a car and operate machinery Due to the ethyl alcohol content, taking the drug may cause impairment of attention and affect the ability to drive a car or operate machinery.
Package
Oral solution. 120 ml in yellow-brown glass bottles with a plastic screw cap with tamper evident. Each bottle, along with instructions for use, is placed in a cardboard box.
Best before date
4 years. Do not use after the expiration date stated on the package.
Storage conditions
Store at a temperature not exceeding 25 °C. Keep out of the reach of children.
Conditions for dispensing from pharmacies
Over the counter.
Buy Hofitol solution for oral administration in fl. 120ml per pack. No. 1 in pharmacy
Price for Hofitol solution for oral administration in fl. 120ml per pack. No. 1
Instructions for use for Hofitol solution for oral administration in vial. 120ml per pack. No. 1
Hofitol tablets No. 180
Compound
Active ingredient: dry aqueous extract of fresh field artichoke leaves - 200 mg. Excipients: magnesium trisilicate - 12 mg, corn starch - 22 mg, talc - 3 mg, magnesium stearate - 3 mg.
Pharmacokinetics
The effect of the drug Hofitol is the combined effect of its components, so kinetic observations are not possible; Collectively, the components cannot be traced using markers or bioassays. For the same reason, it is impossible to detect drug metabolites.
Indications for use
As part of complex therapy:
- dyskinesia of the biliary tract of the hypokinetic type;
- chronic non-calculous cholecystitis;
- chronic hepatitis;
- cirrhosis of the liver;
- chronic nephritis;
- chronic renal failure.
Contraindications
- cholelithiasis;
- obstruction of the bile ducts;
- acute diseases of the liver, kidneys, biliary and urinary tracts;
- children under 6 years of age (for tablets);
- hypersensitivity to the components of the drug.
Directions for use and doses
Adults are prescribed 2-3 tablets. or 2.5-5 ml of solution for oral administration 3 times a day before meals. The course of treatment is 2-3 weeks.
Children over 6 years old are prescribed 1-2 tablets. 3 times/day before meals. The oral solution, depending on age, is prescribed in a dose ranging from 1/4 to 1/2 of the dose used in adults. The course of treatment is 2-3 weeks.
The doctor determines the need for repeated courses of therapy individually.
Storage conditions
The drug should be stored out of the reach of children at a temperature not exceeding 25°C.
Best before date
3 years. Do not use after the expiration date stated on the package.
Description
Herbal medicine with choleretic and diuretic effects.
Dosage form
Brown film-coated tablets, round, biconvex.
Use in children
Contraindicated in children under 6 years of age.
Action
Herbal preparation. The pharmacological effect of the drug is due to the complex of biologically active substances contained in the leaves of the field artichoke. Cynarin in combination with phenolic acids has a choleretic and hepatoprotective effect. Ascorbic acid, carotene, vitamins B1 and B2, and inulin contained in artichokes help normalize metabolic processes.
It also has a diuretic effect and enhances the excretion of urea.
Side effects
From the digestive system: diarrhea may develop with prolonged use of the drug in high doses.
Other: allergic reactions.
Interaction
The use of Hofitol during pregnancy and lactation (breastfeeding) is possible only under the supervision of a physician.
Overdose
Symptoms: possible increased side effects.
