Pharmacological properties of the drug Docetaxel
a cytostatic semi-synthetic agent of the taxoid group, which is obtained from the biomass of yew needles. Promotes the accumulation of tubulin in microtubules and prevents their disintegration, which causes disruption of the mitosis phase and interphase processes in tumor cells. After a single intravenous administration at a dose of 100 mg/m2 of body surface, the maximum concentration in blood plasma is 3.7 μg/ml. The average values of systemic clearance and equilibrium volume of distribution are 21 l/h per 1 m2 and 113 l, respectively. Binding to blood plasma proteins is more than 90%. About 6% of the administered dose is excreted in the urine, 75% in the feces, mainly in the form of metabolites, and a small part is excreted unchanged.
Research results
- The results of the studies indicate that serious adverse events such as colitis, septic shock and death remain rare over 20 years of use of the drug (approximately 600,000 patients were treated during this period), their incidence is 1 case per 10,000 patients.
- An analysis of reports to French pharmacovigilance identified 47 deaths associated with enterocolitis or septic shock between 1996 and February 2021. These data were transferred to the European Medicines Agency.
Use of the drug Docetaxel
Administered at a dose of 100 mg/m2 by one-hour intravenous infusion every 3 weeks. If severe neutropenia (neutrophilic granulocytes less than 500 per 1 mm3) develops during docetaxel therapy, combined with fever, as well as skin reactions or severe peripheral polyneuropathy, the dose should be reduced to 75 mg/m2. 24 hours before docetaxel administration, all patients are prescribed oral dexamethasone at a dose of 8 mg 2 times a day; Reception is continued for 3 days. This measure helps reduce fluid retention in the body during treatment with docetaxel.
Docetaxel-Sandoz fl. (conc. d/pig. solution d/inf.) 10 mg/ml 8 ml Ebewe Pharma/Austria
First episode: reduce FU dose by 20%Repeat episode: stop that
Characteristics
| Active ingredients (INN) | DOCETAXEL |
| Vacation group | Prescription leave |
| Manufacturer | Ebewe Pharma/Austria |
| VED | Yes |
| Remote selling | No |
Order Features
Important. If the location “Online Pharmacy” is selected in the site menu, ordering the product is possible only at the “Price to order” based on suppliers’ offers. If suppliers do not have goods, only the “Subscribe” option is available if the old price is known, or “To order” when there is no information on the old prices. We ask you to pay attention to the “Availability” Tab - you can order goods at the balances and prices of pharmacies, but to do this you need to select the desired pharmacy in the site menu (next to the “Your pharmacy” field).
This section provides answers to frequently asked questions from visitors to our site.
What is the minimum order amount?
The minimum order amount for regular customers when purchasing from a pharmacy is 400 rubles.
The minimum order amount for regular customers when delivering by courier is RUB 1,500. The minimum order amount for legal entities purchasing goods for their own needs is 400 rubles. Can I get an additional discount?
There are no discounts on the site.
We simply gave up discounts and set a minimum markup on goods, and try to keep prices at such prices that it turns out even cheaper than with the maximum possible discount, and these prices are for all our customers. Accordingly, the discount does not apply to online orders made through. These orders are already at the minimum price, since when ordering, the minimum price is automatically selected from the price at the pharmacy and the price to order. Usually the price “to order” is cheaper than in a pharmacy, it comes to order, with a guarantee of quick redemption, and accordingly the markup is lower than in a pharmacy, since there is no need to keep the goods in stock. If the product is available in the pharmacy and the price in the pharmacy is cheaper, then we take the pharmacy price for this item as a basis.
Can I change my order after I have submitted it?
Adjustment of goods, quantity, change of point of issue, etc.
after you send your order is possible only by the manager after we receive the order, when the manager contacts you to clarify the order. In the buyer's personal account, only the ability to cancel or repeat orders is available. To adjust your order, you need to contact the contact manager of the pharmacy - the order pick-up point indicated on the “Contacts” page of the website. Can I contact the pharmacy myself to find out if my order has arrived?
You can call the pharmacy using the numbers listed on the website.
OUR PHARMACIES, ADDRESSES, TELEPHONES What will happen to my order if I don’t buy it within 5 days, and when can I pick it up later?
If you have not purchased your order within 5 days, your order will be canceled and the product will be put up for sale at the retail price in the pharmacy. And you will have to make a new order on the website.
If you ordered a product on the website and did not come for it within 5 days from the date of receipt, your data will be blacklisted (emergency), and a new order will be possible only after making a deposit on the order in the amount of 30% of its cost. If you refuse to purchase your order, the deposit amount will not be returned.
When you first add to an emergency situation, a warning is sent that the next time you find yourself in an emergency situation again, you will not be able to place orders.
Those buyers who systematically do not redeem their orders on time, as well as those who do not buy all the goods from the order, but only part of them, also fall into emergencies.
If I cannot pick up my order on the day it arrives at the pharmacy, can I redeem it later?
Your order is stored in the Pharmacy for 5 days from the date of receipt, during which time you can pick up your order.
When can I receive my product after ordering?
After sending the order, an SMS message about the order will be sent to the mobile phone number you specified, for example: “Zdravstvujte, Vladimir! Vy oformili zakaz No. 1234 na summu RUR 2345.50 Ozhidajte zvonka iz apteki.”, then during the working day, from 9-00 to 17-30, the APTEKA-INFO.RU service manager will contact you to confirm your application, then the application will be sent to the supplier , will be collected there and delivered to the pharmacy of your choice on the next business day.
Important.
Applications are processed only on weekdays from 9-00 to 17-30.
Applications accepted and processed on Friday will be delivered to the pharmacy on Monday or Tuesday. It is possible to speed up the order readiness; the exact date of order readiness is agreed upon with the manager. Applications received on weekends (Saturday, Sunday) will be accepted and processed on the next business day, and delivered on Tuesday-Wednesday.
When agreeing on an order, we warn you about the approximate time frame for the entire order to be ready in order to avoid misunderstandings.
How will I know that my order has been delivered to the pharmacy?
When the goods arrive at the pharmacy, you will receive a letter about the readiness of your order and an SMS notification, then they will call you and inform you that you can come and pick up your order. If you do not redeem your order within 1-2 days from the moment it is ready, they will call you and remind you that it is ready.
Important.
All letters and SMS are sent automatically when the status of the order changes, but sometimes situations are possible when the letter and SMS are ahead of the delivery of your order to the pharmacy, mainly due to an error by the workers processing the order.
A phone call from the pharmacy is a 100% guarantee that your order has already arrived at the pharmacy and you can receive it. So please wait for this call.
If you want to clarify the status of your order, you need to call the pharmacy where the order is issued and provide your name and order number.
Is it possible to pick up the ordered goods?
Pickup is the main way to receive an order on our service, since most orders contain medications that we cannot deliver to you by courier.
You can independently pick up the ordered goods at our pharmacies - delivery points, this is convenient, we have 4 pharmacies in Tomsk and 1 in Seversk. How is delivery to the regions carried out?
Delivery to regions is not possible.
We work only in Tomsk and Seversk. Is it possible to order medicine to be delivered to your home?
The delivery of prescription drugs is prohibited by the current legislation of the Russian Federation.
Delivery of over-the-counter medicines is permitted only if there is a license for the remote sale of medicines.
APTEKA-INFO is working to resolve the delivery issue, but unfortunately we do not yet have the necessary license, so home delivery is not possible.
We deliver orders containing medications only to our pharmacies.
You can choose any pharmacy convenient for you from those presented on and redeem your order at the selected pharmacy.
There are prescription drugs on the site, can I order them and get them at the pharmacy?
You can order prescription goods, but when purchasing from a Pharmacy for any prescription drug, you have the right to require a prescription, and if you do not have a prescription, the Pharmacy has the right not to issue your order. When confirming an order by the buyer at the stage of its pre-processing, the service manager usually always checks whether the buyer has a prescription; if it is not available, prescription products are excluded from the order. The items in your order are not a single item, and you will be able to receive over-the-counter drugs included in your order.
Attention!
Buyers who regularly fail to redeem part or all of their orders risk being blacklisted. If a buyer is blacklisted, a restriction is included - when ordering rare drugs and goods, the pharmacy has the right to demand from the buyer:
1) making a deposit - if, when the buyer refuses to buy these goods, the service has problems with further sales, since the goods are very rare, are not in rare and everyday demand, or the supplier refuses to return such goods. The deposit amount in this case is not refundable.
2) making an advance payment - if the product is rare, but it is still bought by ordinary customers in pharmacies.
Making an advance payment in this case is an additional guarantee that the buyer really intends to purchase this product. In case of cancellation of the purchase, the advance payment is returned to the buyer in full. Why do “to order” prices on the website differ from prices in pharmacies?
We try to keep prices minimal for our clients, so prices for drugs on our website are usually lower than in pharmacies and apply only to online orders made on the website.
The “made to order” price is formed based on suppliers’ proposals. Prices in a pharmacy are individual, since prices from suppliers change every day, all pharmacies work independently and receive goods on different days and months, so prices in pharmacies are all different. If you urgently need medicine on the same day, and at a low price, you can find information about the availability and prices of the product on its page, in the “Availability” tab, there is information about stock and prices in our pharmacies.
How can an organization purchase medicines and goods?
Due to the introduction of labeling for drugs, a large number of labeled drugs, and the lack of profitability of this activity, we are forced to stop working with legal entities on drugs that have a labeling sign.
Therefore, on our website, legal entities can no longer purchase medicines and medical products by bank transfer.
The opportunity to register and place orders remains available for legal entities. But working by bank transfer and receiving sales and accompanying documents for orders is impossible.
We continue to accept applications from medical centers, hospitals, medical institutions, medical units, beauty salons, private offices, etc., who need medicines and over-the-counter medicines and other goods and medical products that do not have a label, as well as parapharmaceutical products for “own needs”, as well as from organizations that maintain their production first aid kits fully equipped.
Our conditions and a brief procedure for working with legal entities:
Our contacts +7 (952) 175-59-29
Online pharmacy
2021 © Service for ordering and delivery of medicines from the pharmacy chain "APTEKA-INFO" All information presented on this Internet resource, including the availability and prices of goods, is for reference only and does not constitute a public offer or an invitation to make such offers, in accordance with Article 437 of the Civil Code Russian Federation. Check the information at the help desk by phone: +7(952) 175-59-29.
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