Pimafucin cream: detailed instructions for use, what it helps with, analogues and reviews from women


Components and action

The instructions describe in detail the composition of the drug, presented:

  • natamycin;
  • potato starch;
  • stearic acid;
  • milk sugar;
  • polyvinylpyrrolidone;
  • sucrose;
  • cellulose acetate phthalate;
  • glycerol triacetate;
  • food additive E 218, E 170;
  • white clay;
  • talc;
  • titanium dioxide;
  • gum arabic;
  • gelatin;
  • white beeswax.

The antifungal antibacterial agent has a fungicidal spectrum of action. When ingested, the active ingredient binds to ergosterol from the cell membrane of the mycosis cell, which provokes a disruption of its structure, loss of cytoplasmic contents and subsequent death.

The medicine is available in tablets of 100 mg, each package contains 20 units.

special instructions

The suppositories quickly dissolve inside the body. If the suppositories are not effective enough, capsules and cream are added.

The candles contain alcohol, which may cause minor skin irritation. During menstruation, you should stop taking suppositories. It is advisable to avoid sexual intercourse during treatment with the drug. If this is not possible, use barrier contraceptives.

If necessary, can be used in infants.

The shelf life of the drug is one year. The product is sold without a doctor's prescription. The medicine should be stored in a cool, dry place.

When used correctly, there is no overdose. Interaction with other agents has not been studied.

Indications for use and contraindications

The abstract recommends the use of Pimafucin for patients:

  • with intestinal candidiasis;
  • acute pseudomembranous and atrophic fungal infection with extreme exhaustion of the body, weak immunity, after antibiotic therapy, treatment with cytostatics or glucocorticosteroids;
  • damage to the skin and mucous membranes in the presence of vaginitis, vulvitis, vulvovaginitis.

The drug is not prescribed to patients with individual intolerance to its components.

Instructions for use

The instructions for use of Pimafucin cream recommend treatment after consultation with a doctor. The characteristic symptoms of candidiasis often mask the clinical manifestations of a bacterial infection. What caused the inflammation can only be determined by laboratory diagnostics of a biological sample. As a result of the study, the species of microorganisms and their sensitivity to drugs are established.

If a fungal infection is detected, the attending physician determines the duration of the therapeutic course:

  • 7-10 days for minor damage to mucous membranes or skin;
  • more than 10 days if a chronic recurrent pathology is detected.

After the symptoms disappear, treatment should not be stopped.

Pimafucin is a powerful antifungal agent. Therefore, the severity of signs of the inflammatory process is significantly reduced after the first use of the drug. But pathogenic fungi are deactivated and not completely destroyed.

If the treatment course is not completed, then with the slightest decrease in immunity, another relapse will occur. The patient is considered recovered if there are no infectious agents in the control samples.

The cream is used to eliminate fungus on the nails. But it is not active against all pathogens of onychomycosis. And the thick consistency of the product prevents the penetration of natamycin into the nail plates. Dermatologists recommend using drugs in the form of solutions or varnishes for treatment.

Indications and contraindications

According to the instructions for use, Pimafucin cream is used in the treatment of thrush in women and men. If necessary, its effect is enhanced and prolonged by anti-inflammatory and antiseptic medications. Indications for the use of an antimycotic agent include the following pathologies:

  • vulvitis, vulvovaginitis, vaginitis of fungal or mixed etiology;
  • balanoposthitis – inflammatory diseases of the skin of the penis;
  • oral candidiasis;
  • atrophic or pseudomembranous candidiasis;
  • acute or chronic otitis of various parts of the ear;
  • ringworm.

Sometimes the cream is recommended from the first days of antibiotic therapy, a course of cytostatics, and glucocorticosteroids. All these drugs negatively affect not only the intestinal microbiocenosis, but also destroy the beneficial bacteria of the vagina. Therefore, doctors prescribe antimycotics to prevent the development of candidiasis.

The only contraindication to the use of the cream is hypersensitivity to the ingredients of Pimafucin.

Directions for use and doses

The dosage regimen is determined by the doctor individually for each patient, taking into account the degree of fungal tissue damage. To treat mucosal candidiasis, a 1-2 cm strip of cream squeezed out of a tube is sufficient. For mycoses affecting large surfaces of the skin, 3-5 cm of external agent is required.

How to apply Pimafucin cream to women and men:

  • with thrush, the mucous membranes and vestibule of the vagina are lubricated;
  • for the treatment of balanoposthitis, the drug is evenly distributed over the inflamed areas of the penis.

The product is applied several times a day in a thin layer and lightly rubbed into the damaged tissue. To treat otitis media, cream is placed in the ear, and then a turunda made of sterile cotton wool is inserted.

In the treatment of fungal infections of the skin and mucous membranes, antimycotic agents are combined with antiseptics. These are solutions of Miramistin, Chlorhexidine, Furacilin, infusions of medicinal herbs - chamomile, string, marigold. Before applying the cream, they treat damaged tissues.

Side effects and special instructions

During treatment of fungal skin diseases, local adverse reactions rarely occur. Their appearance is usually caused by a violation of the dosage regimen - exceeding the frequency of use. In such cases, the skin swells and turns red, and small rashes form. Strict adherence to medical recommendations helps minimize the likelihood of side effects of Pimafucin cream.

Much more often the negative effect of the drug is manifested when applied to the mucous membranes.

It contains components that have drying properties. Uncomfortable sensations arise - itching, burning, stinging. They usually disappear a few minutes after using Pimafucin. But if discomfort persists for a long time, you should consult a doctor. He will adjust the dosage or replace the drug with an active analogue.

Pregnancy and lactation

The active substance is not absorbed into the systemic bloodstream if there are no microtraumas on the mucous membranes and skin. This explains the rare clinical manifestations during therapy.

Pimafucin cream is used in the treatment of candidiasis in any trimester of pregnancy and during lactation. But before using ointment for thrush, a woman should be examined by a gynecologist.

Drug interactions

The interaction of Pimafucin cream (gel) with other drugs has not been established. Gynecologists recommend not douching for 2 hours after applying the product. Otherwise, its therapeutic effectiveness will decrease.

Side effect

Therapeutic manipulations can cause the appearance of non-standard responses of the body. Taking Pumafucin can provoke the appearance of:

  • attacks of nausea;
  • dyspeptic disorders with diarrhea.

Side effects occur on the first day of using the tablets and disappear spontaneously during treatment. If these symptoms or other reactions not described in the instructions occur, the patient should visit the attending physician and describe in detail the changes that have occurred in the general condition.

Reviews

Evgeniya, Kislovodsk

During pregnancy, she fell ill with bronchitis, and as a result, thrush developed. Before conception, I always used Pimafucin suppositories for insertion into the vagina. I asked the doctor if it was possible to use suppositories during pregnancy. The doctor recommended using a safer cream.

Valeria, Barnaul

As soon as I get a little cold, symptoms of thrush appear. Pimafucin cream helps a lot. Dry mucous membranes, pain and burning disappear after the first application of the drug. But I always use it for at least 5-7 days.

Pimafucin cream (review) from 250 rub.
Overall

4.4

  • Efficiency
  • Price
  • Safety
  • Availability

Pros

  • Safety
  • Efficiency
  • Does not leave greasy stains

Cons

  • Side effects
  • Price
  • Small volume

Admission rules

Oral tablets are used at any time; food does not have any effect on the effectiveness of the drug. The dosage of the drug depends on the current pathology and age of the patient:

  1. Intestinal candidiasis - for adults, one tablet four times a day. For children, the dosage is one pill twice a day, the duration of manipulation is one calendar week.
  2. Vaginitis caused by a fungus - 1 piece four times a day, for 10-20 days. In parallel, suppositories of the same name are used to sanitize the source of infection and accelerate the healing process (transition to the remission stage in chronic disease).

The duration of course therapy can be set individually for each patient. After the disappearance of clinical signs of pathology, treatment continues for several days.

When is it appointed?

This drug is effective not only for thrush, but also for other fungal diseases. It also has a fungicidal effect. Acts on yeast fungi, in particular on fungi of the Candida type, pathogenic fungi, dermatophytes. The substance does not penetrate the skin or mucous membranes. Excreted through the intestines.

This medicine is used in tablets for:

  • fungal infection of the inner ear;
  • fungi of the oral mucosa;
  • intestinal candidiasis due to the use of antibiotics;
  • vulvitis and vaginitis;
  • atrophic candidiasis;
  • thrush.

Pimafucin ointment is used for:

  • fungi of nails, mucous membranes, skin;
  • vaginal thrush;
  • vaginitis;
  • dermatomycosis;
  • otitis caused by fungi;
  • candidiasis of nails, skin;
  • simultaneous therapy of the sexual partner.

"Pimafucin" in suppositories is prescribed for:

  • vaginitis caused by candida fungi;
  • balanoposthitis;
  • vulvovaginitis.

Manufacturer's instructions

The annotation states that the drug contains milk sugar and sucrose, which people with congenital diseases should pay attention to:

  • with allergies to galactose, fructose;
  • lactase deficiency;
  • impaired absorption of glucose/galactose in the small intestine;
  • combined deficiency of sucrase and isomaltase enzymes.

If the patient has at least one of the above pathologies, then he must warn the local doctor about the problem before starting therapeutic procedures. The specialist will assess the risks and search for a more suitable medicine that is similar in effect to the main one.

This dosage form of Pimafucin is not used in the treatment of infants due to the inability to swallow tablets normally. For children under one year of age, there are other forms and varieties of antifungal and antibacterial agents.

During therapy, the active components of the drug do not affect the rate of reactions. During therapy, it is allowed to drive vehicles and work with moving complex mechanisms.

There is no information about the possible interaction of alcohol with the medicine. The manufacturer does not recommend the consumption of alcoholic beverages during treatment procedures. During clinical studies, the interaction of the antibiotic with other medications was not recorded.

Description of the drug

Pimafucin cream is a white product with a yellowish tint with a thick consistency and no characteristic odor. It is intended for the treatment of pathologies caused by yeast-like fungi. These microorganisms belong to opportunistic microflora and do not show themselves for a long time. But with a sharp decrease in immunity, fungi rapidly become more active.

Clinical manifestations of infection include sticking in the corners of the mouth and cheesy discharge from the urethra or vagina. Red spots on the skin indicate a mycotic lesion. All diseases are dangerous, contagious, and require immediate medical intervention. Antifungal drugs are used in therapy, including Pimafucin ointment.

What is the topical application prescribed for:

  • mycotic lesions of the skin and mucous membranes;
  • fungal infection of the nail plates on the hands and feet;
  • bacterial pathologies of the ear, complicated by an associated mycotic infection;
  • vaginal candidiasis.

The cream works effectively after the first application to pathological lesions. It helps to quickly get rid of the symptoms of a fungal disease by destroying its pathogens.

When diagnosing an uncomplicated pathology, it is sufficient to use only the cream. When a recurrent disease is detected, other medications are included in the therapeutic regimen. Usually these are tablets of the same name and intravaginal suppositories.

Pimafucin helps well against vaginal candidiasis, but treatment is indicated for both sexual partners. Women are prescribed suppositories or cream, and men only cream.

Clinical and pharmacological group

The cream is an external agent from the clinical-pharmacological group of antimycotic drugs. The active ingredient is a polyene antifungal antibiotic, so Pimafucin can be classified as an antimicrobial agent.

pharmachologic effect

Low concentrations of natamycin have a fungistatic effect.
A polyene antibiotic from the macrolide group inhibits the growth and reproduction of pathogenic fungi. This property is often used for prophylactic purposes to prevent the spread of infection. Natamycin in high concentration exhibits powerful fungicidal activity. It prevents fungi from producing ergosterols, the structural elements of membranes. As a result, the integrity of the entire cell is disrupted, so it quickly collapses.

Pimafucin is a broad-spectrum antimycotic agent. It is active against the following fungal species:

  • yeast-like fungi Candida - causative agents of oral candidiasis and thrush;
  • dermatophytes that cause severe skin lesions.

Pimafucin is one of the few antimycotics that are used throughout treatment. The fact is that fungi are not capable of developing resistance to natamycin.

Release form and composition

The Pimafucin therapeutic line includes three of its dosage forms. This is a cream for application to the skin and mucous membranes, vaginal suppositories and tablets for oral administration. All drugs contain one active substance with pronounced antifungal activity - natamycin.

The Italian manufacturer packages the cream in a plastic or aluminum tube of 30 g. The secondary packaging for the drug is a yellow cardboard box with attached instructions for use.

In addition to natamycin, Pimafucin cream contains the following auxiliary components:

  • macrogol;
  • cetostearyl alcohol;
  • sodium lauryl sulfate;
  • distilled water;
  • methylparaben;
  • propylparaben;
  • wax.

Additional ingredients ensure maximum absorption of the antibiotic into the mucous membranes and skin.

Many of them have weak antiseptic properties, which enhances the therapeutic effect of the drug. The components of the product form protective shells, preventing bacterial infection of tissues affected by inflammation.

Storage conditions and periods

The shelf life of the antimycotic drug is 24 months, after the seal of the tube is broken - 3-4 weeks. It should be stored at room temperature in a dark place out of reach of small children. Freezing Pimafucin cream is not allowed. If the consistency, color changes, or a rancid odor appears, the product is not suitable for treatment.

Standards for storage and sale

The drug is stored in dry, dark rooms at a temperature of up to 25 degrees. Tablets should be kept in a safe distance from children and pets. The medicine is valid for 4 years, after the expiration date written on the packaging, it is disposed of along with household waste.

You can buy Pimafucin at any of the available regular or online pharmacies. The average price for a medicine starts from 425 rubles, the final cost depends on the availability of discounts and promotions. Trading platforms deliver the drug to order.

Analogs

The average cost of Pimafucin cream in pharmacies is 350 rubles. Cheaper analogs are available in the form of vaginal suppositories - Clotrimazole, Nystatin ointment, Hexicon, Chlorhexidine.

In what cases can a doctor prescribe medication for a child?

The main range of use of the drug in children is thrush caused by pathogenic fungi of the genus Candida. These microorganisms constantly live in the human body and belong to opportunistic microflora. A child often becomes infected with them in the first days of life from his mother.

Fungi do not manifest themselves for a long time and do not have any adverse effects on the baby’s body. But with a sharp decrease in immunity or an unbalanced diet, Candida rapidly activates. Typically, fungi affect the skin and mucous membranes of the genital organs, causing redness and itching. Infants have many folds on their body, into which pathogenic microorganisms also penetrate.

Dermatologists prescribe Pimafucin when diagnosing the following symptoms:

  • discharge of a cheesy mass from the urethra in boys, indicating the development of balanoposthitis;
  • the appearance of thick whitish discharge in girls - the main sign of thrush, fungal vaginitis and vulvovaginitis.

These pathologies are always accompanied by burning, stinging and other uncomfortable sensations. The skin and mucous membranes of the genital organs look swollen, red and inflamed. Often pathological foci are localized in other parts of the epidermis. Doctors suspect a fungal skin infection when a small rash forms. If left untreated, blisters with liquid contents form on the child’s skin.

At what age is it allowed to take Pimafucin?

According to the instructions for use, Pimafucin ointment for children can be used from the first days of life. It does not contain aggressive chemical compounds that can harm the baby. Side effects are rare. As a rule, this happens when parents exceed dosages in the hope of speeding up recovery.

Treatment with cream always gives a quick positive result, so there is no need to violate the dosage regimen.

Redness and swelling of the skin often indicates the development of candidiasis. But using Pimafucin without a doctor’s prescription is strictly prohibited, and here’s why:

  • clinical manifestations of fungal diseases are similar to the symptoms of bacterial infections;
  • improper treatment will cause the pathology to progress and become chronic.

When diagnosing mild thrush, a dermatologist may include only antiseptics in the therapeutic regimen. Regular treatment of the skin with them and adherence to hygiene rules will allow you to do without antifungal agents. The Pimafucin therapeutic line also includes tablets and vaginal suppositories.

The tablet form is usually used in children from 3 years of age. The drug is enteric coated, so it cannot be crushed or dissolved in water. It is prescribed only if the child can swallow the whole tablet. Vaginal suppositories are rarely used in the treatment of children.

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