Fungoterbin, 1 piece, 15 g, 1%, cream for external use


Compound

The tablets contain 250 mg of the active substance terbinafine and additional elements (kollidon 30, benzoic acid, microcrystalline cellulose, kollidon CL-M, aerosil, magnesium stearate).
Cream (ointment) for external use contains 1 gram of the active ingredient - terbinafine hydrochloride per 100 grams of product. The medicine also contains: urea, cetostearyl alcohol, imidomerea, liquid paraffin, water, butylated hydroxytoluene, macrogol cetostearate, poloxamer, propylene glycol, petroleum jelly.

Spray (1 gram) contains: 10 mg of terbinafine hydrochloride, urea, ethyl alcohol, propylene glycol, dibunol, povidone.

Release form

Fungoterbin®

Tablets, 250 mg. In contour cell packaging made of PVC film and printed varnished aluminum foil 7 or 10 pcs. 1 or 2 blister packs in a cardboard pack.

Cream for external use, 1%. In aluminum or PE laminate tubes, 15 g. 1 tube in a cardboard pack.

Spray for external use, 1%. In polymer bottles with a dispenser pump, 15 or 30 ml. 1 fl. in a cardboard box.

Fungoterbin® Neo

Cream for external use. In aluminum tubes or PE laminate tubes, 10, 15, 20, 25, 30, 40, 50 or 100 g. 1 tube in a cardboard pack.

Gel for external use. In aluminum tubes or PE laminate tubes, 10, 15, 20, 25, 30, 40, 50 or 100 g. 1 tube in a cardboard pack.

Pharmacodynamics and pharmacokinetics

Active ingredient with a broad antifungal spectrum of action. Terbinafine stops the synthesis of ergosterol (inhibits the enzyme squalene epoxidase ), thereby disrupting the biosynthetic processes in fungal cells. The drug is active against dimorphic fungi, dermatophytes and various molds .

The medicine does not affect hormonal levels or the metabolism of other drugs. The urea contained in the product promotes better penetration of the product into cells and accelerates tissue repair processes in areas affected by the fungus.

After taking the tablets for 2 hours, the maximum is reached. concentration in blood plasma. About 90% of the substance binds to proteins in plasma.

The substance tends to accumulate in the sebaceous glands, hair follicles , hair, and after 7-14 days of regular use - in the nail plates and the stratum corneum of the skin .

The half-life is 16-19 hours, the drug is excreted through the kidneys (its inactive metabolites ) and with the stratum corneum of the skin. For persons with liver or kidney disease, the elimination period from the body may be prolonged.

When using cream and spray, approximately 5% of the active substance enters the blood plasma, which does not in any way affect the processes occurring in the body.

Directions for use and doses

Fungoterbin®

Pills

Inside, after eating.

The duration of treatment and dosage regimen are determined individually and depend on the location of the process and the severity of the disease.

Adults - usually 1 tablet. (250 mg) 1 time per day. Patients with liver and kidney failure - 1/2 table. (125 mg) 1 time per day.

Mycoses of the skin: recommended duration of treatment: dermatomycosis of the feet (interdigital, plantar or “sock” type) - 2–6 weeks; dermatomycosis of the trunk, limbs - 2–4 weeks; candidiasis of the skin and mucous membranes - 2–4 weeks. Complete disappearance of the clinical manifestations of the disease is usually observed several weeks after mycological cure.

Mycosis of the scalp: recommended duration of treatment: mycosis of the scalp - about 4 weeks. Mycoses of the scalp are observed mainly in children.

Onychomycosis: the duration of treatment with the drug in most patients is 6–12 weeks. For onychomycosis of the fingers, in most cases it is 6 weeks, and for onychomycosis of the toes - 12 weeks. Some patients who have a reduced rate of nail growth may require longer treatment. The optimal clinical effect is observed several months after mycological cure and cessation of therapy. This is determined by the period of time required for a healthy nail to grow back.

The drug is prescribed to children from 2 years of age. The dose depends on the child’s body weight: children weighing up to 20 kg - 62.5 mg/day (1/4 table); from 20 to 40 kg - 125 mg/day (1/2 table); more than 40 kg - 250 mg/day (1 table). There are no data on the use of the drug in children under 2 years of age (weight <12 kg).

Cream

Externally. Before use, it is necessary to clean and dry the affected areas. Fungoterbin® is applied 1 or 2 times a day to the affected skin and adjacent areas. Apply the cream in a thin layer and rub in lightly. When applied to the area of ​​skin folds (groin area, intergluteal area, under the mammary glands), it is recommended to apply a gauze bandage/bandage.

Dermatomycosis of the trunk, large folds, legs: 1 time per day, duration of treatment - 1 week.

Dermatomycosis of the feet: 1 time per day, duration of treatment - 1 week.

Skin candidiasis: 1-2 times a day, duration of treatment - 1-2 weeks;

Lichen versicolor: 1-2 times a day, treatment duration - 1 week.

Spray

Externally. The drug is applied to the skin 1 or 2 times a day. Before applying the spray, it is necessary to clean and dry the affected areas. The drug is sprayed onto the affected areas in an amount sufficient to thoroughly moisturize them, and, in addition, applied to adjacent areas of both affected and intact skin.

Average duration and frequency of use

Dermatomycosis of the trunk, legs: 1 week, 1 time per day.

Ringworm of the feet: 1 week, 1 time per day.

Skin candidiasis: 1–2 weeks 1 or 2 times a day.

Tinea versicolor: 1 week 1 or 2 times a day.

Experience with the use of Fungoterbin® spray in children is limited, and therefore its use in children under 12 years of age is not recommended.

Fungoterbin® Neo

Cream

Externally. The drug is applied to the skin 1 or 2 times a day. Before applying the cream, it is necessary to clean and dry the affected areas. The cream is applied in a thin layer to the affected skin and lightly rubbed. To increase the effectiveness of treatment, it is possible to use occlusive dressings. For infections accompanied by diaper rash (under the mammary glands, in the spaces between the fingers, between the buttocks, in the groin area), the places where the cream is applied can be covered with gauze, especially at night.

The duration of treatment depends on the indication and severity of the disease.

Duration and frequency of use

Dermatomycosis of the trunk, legs: 1 time per day for 1 week.

Dermatomycosis of the feet: 1 time per day for 1 week.

Skin candidiasis: 1 or 2 times a day for 1–2 weeks.

Tinea versicolor: 1 or 2 times a day for 2 weeks.

Gel

Externally. The drug is applied to the skin 1 or 2 times a day. The gel is applied in a thin layer to the affected skin and lightly rubbed. To increase the effectiveness of treatment, it is possible to use occlusive dressings. For infections accompanied by diaper rash (under the mammary glands, in the spaces between the fingers, between the buttocks, in the groin area), the places where the gel is applied can be covered with gauze, especially at night.

Average duration and frequency of use

Dermatomycosis of the trunk, legs: 1 week, 1 time per day.

Ringworm of the feet: 1 week, 1 time per day.

Skin candidiasis: 1–2 weeks 1 or 2 times a day.

Tinea versicolor: 1 week 1 or 2 times a day.

Indications for use

Tablets are used:

  • for the treatment of fungal skin infections caused by Trichophyton spp. (Trichophyton rubrum, Trichophyton verrucosum, Microsporum canis, Trichophyton mentagrophytes, Trichophyton violaceum, Epidermophyton floccosum);
  • for candidiasis ;
  • for the treatment of lichen versicolor ;
  • for mycoses of the feet ;
  • when dermatophytes smooth skin or groin areas.

Fungoterbin ointment is prescribed for local treatment as part of complex therapy for the above diseases.

The spray is usually used to treat seborrhea that occurs on the hairy part of the scalp.

Contraindications

The drug is not prescribed:

  • children under 12 years old;
  • if you are allergic to its components;
  • pregnant and lactating women.

The tablet form should not be used by persons with kidney and liver or lactase deficiency .

Please be careful:

  • for tumors of various kinds;
  • for lupus erythematosus ;
  • alcoholics;
  • for problems with hematopoiesis;
  • with pathological processes in blood vessels;
  • for metabolic disorders.

Fungoterbin, 1 piece, 30 ml, 1%, spray for external use

Fungoterbin®

Pills

Inside,

after meal.

The duration of treatment and dosage regimen are determined individually and depend on the location of the process and the severity of the disease.

Adults - usually 1 tablet. (250 mg) 1 time per day. Patients with liver and kidney failure - 1/2 table. (125 mg) 1 time per day.

Mycoses of the skin:

Recommended duration of treatment: tinea pedis (interdigital, plantar or sock-type) - 2-6 weeks; dermatomycosis of the trunk, limbs - 2–4 weeks; candidiasis of the skin and mucous membranes - 2–4 weeks. Complete disappearance of the clinical manifestations of the disease is usually observed several weeks after mycological cure.

Mycoses of the scalp:

Recommended duration of treatment: mycosis of the scalp - about 4 weeks. Mycoses of the scalp are observed mainly in children.

Onychomycosis:

The duration of treatment with the drug in most patients is 6–12 weeks. For onychomycosis of the fingers, in most cases it is 6 weeks, and for onychomycosis of the toes - 12 weeks. Some patients who have a reduced rate of nail growth may require longer treatment. The optimal clinical effect is observed several months after mycological cure and cessation of therapy. This is determined by the period of time required for a healthy nail to grow back.

The drug is prescribed to children from 2 years of age. The dose depends on the child’s body weight: children weighing up to 20 kg - 62.5 mg/day (1/4 table); from 20 to 40 kg - 125 mg/day (1/2 table); more than 40 kg - 250 mg/day (1 table). There are no data on the use of the drug in children under 2 years of age (weight <12 kg).

Cream

Externally.

Before use, it is necessary to clean and dry the affected areas. Fungoterbin® is applied 1 or 2 times a day to the affected skin and adjacent areas. Apply the cream in a thin layer and rub in lightly. When applied to the area of ​​skin folds (groin area, intergluteal area, under the mammary glands), it is recommended to apply a gauze bandage/bandage.

Dermatomycosis of the trunk, large folds, legs:

1 time per day, duration of treatment - 1 week.

Ringworm of the feet:

1 time per day, duration of treatment - 1 week.

Skin candidiasis:

1-2 times a day, duration of treatment - 1-2 weeks;

Tinea versicolor:

1-2 times a day, duration of treatment - 1 week.

Spray

Externally.

The drug is applied to the skin 1 or 2 times a day. Before applying the spray, it is necessary to clean and dry the affected areas. The drug is sprayed onto the affected areas in an amount sufficient to thoroughly moisturize them, and, in addition, applied to adjacent areas of both affected and intact skin.

Average duration and frequency of use

Dermatomycosis of the trunk, legs:

1 week 1 time per day.

Ringworm of the feet:

1 week 1 time per day.

Skin candidiasis:

1–2 weeks 1 or 2 times a day.

Tinea versicolor:

1 week 1 or 2 times a day.

Experience with the use of Fungoterbin® spray in children is limited, and therefore its use in children under 12 years of age is not recommended.

Fungoterbin® Neo

Cream

Externally.

The drug is applied to the skin 1 or 2 times a day. Before applying the cream, it is necessary to clean and dry the affected areas. The cream is applied in a thin layer to the affected skin and lightly rubbed. To increase the effectiveness of treatment, it is possible to use occlusive dressings. For infections accompanied by diaper rash (under the mammary glands, in the spaces between the fingers, between the buttocks, in the groin area), the places where the cream is applied can be covered with gauze, especially at night.

The duration of treatment depends on the indication and severity of the disease.

Duration and frequency of use

Dermatomycosis of the trunk, legs:

1 time per day 1 week.

Ringworm of the feet:

1 time per day 1 week.

Skin candidiasis:

1 or 2 times a day for 1–2 weeks.

Tinea versicolor:

1 or 2 times a day for 2 weeks.

Gel

Externally.

The drug is applied to the skin 1 or 2 times a day. The gel is applied in a thin layer to the affected skin and lightly rubbed. To increase the effectiveness of treatment, it is possible to use occlusive dressings. For infections accompanied by diaper rash (under the mammary glands, in the spaces between the fingers, between the buttocks, in the groin area), the places where the gel is applied can be covered with gauze, especially at night.

Average duration and frequency of use

Dermatomycosis of the trunk, legs:

1 week 1 time per day.

Ringworm of the feet:

1 week 1 time per day.

Skin candidiasis:

1–2 weeks 1 or 2 times a day.

Tinea versicolor:

1 week 1 or 2 times a day.

Side effects

hypersensitivity on the skin, itching , burning sensation, rashes, even urticaria and Quincke's edema may occur . It is necessary to distinguish between different types of adverse reactions.

Also, when taking the pills, the following were observed:

  • arthralgia or agranulocytosis ;
  • pain in the epigastric region;
  • indigestion;
  • lymphopenia;
  • anorexia;
  • distortion of taste;
  • thrombocytopenia;
  • neutropenia;
  • myalgia;
  • Steven-Johnson syndrome.

Instructions for use (Method and dosage)

Depending on the disease and its severity, different dosages and dosage forms of the drug are recommended.

Instructions for Fungoterbin tablets

The tablets are taken orally, preferably after meals.

Adults are prescribed 250 mg of the drug per day, once.

For mycoses on the skin, the recommended course of treatment is from 2 to 6 weeks. For mycoses of the scalp, the course of treatment is one month.

For onychomycosis, the duration of taking tablets is from 6 to 12 weeks, depending on the location of the fungus.

Improvements in the appearance of the skin or nails occur a couple of weeks or even months after treatment.

For children over 2 years of age, the daily dosage is calculated from the ratio of 0.32 mg per kg of weight. Accordingly, if a child weighs up to 20 kg, the daily dosage is a quarter of a tablet, up to 40 - half, more than 40 - a whole tablet.

The recommended dosage for patients with renal failure and liver disease is 125 mg per day.

Fungoterbin cream, instructions for use

The ointment is used exclusively externally. The affected area should be cleaned and dried before use.

The cream is applied 1-2 times a day, depending on the disease, to the affected areas and rubbed in a little. Sometimes it becomes necessary to apply a gauze bandage.

For dermatomycosis of the skin, legs, folds of the skin and feet, the drug is applied once a day for a week.

For candidiasis – 2 times a day, 7 days.

For lichen versicolor, the duration of treatment is a week, the frequency of application is 1 or 2 times a day.

Instructions for the spray

For external use. The product is also applied to previously cleaned and dried areas. After application, the skin should become evenly moist. In addition to the affected areas, it is recommended to treat the adjacent skin.

The frequency of administration is the same as for the cream.

Fungoterbin, 1 piece, 15 g, 1%, cream for external use

Fungoterbin®

Pills

Inside,

after meal.

The duration of treatment and dosage regimen are determined individually and depend on the location of the process and the severity of the disease.

Adults - usually 1 tablet. (250 mg) 1 time per day. Patients with liver and kidney failure - 1/2 table. (125 mg) 1 time per day.

Mycoses of the skin:

Recommended duration of treatment: tinea pedis (interdigital, plantar or sock-type) - 2-6 weeks; dermatomycosis of the trunk, limbs - 2–4 weeks; candidiasis of the skin and mucous membranes - 2–4 weeks. Complete disappearance of the clinical manifestations of the disease is usually observed several weeks after mycological cure.

Mycoses of the scalp:

Recommended duration of treatment: mycosis of the scalp - about 4 weeks. Mycoses of the scalp are observed mainly in children.

Onychomycosis:

The duration of treatment with the drug in most patients is 6–12 weeks. For onychomycosis of the fingers, in most cases it is 6 weeks, and for onychomycosis of the toes - 12 weeks. Some patients who have a reduced rate of nail growth may require longer treatment. The optimal clinical effect is observed several months after mycological cure and cessation of therapy. This is determined by the period of time required for a healthy nail to grow back.

The drug is prescribed to children from 2 years of age. The dose depends on the child’s body weight: children weighing up to 20 kg - 62.5 mg/day (1/4 table); from 20 to 40 kg - 125 mg/day (1/2 table); more than 40 kg - 250 mg/day (1 table). There are no data on the use of the drug in children under 2 years of age (weight <12 kg).

Cream

Externally.

Before use, it is necessary to clean and dry the affected areas. Fungoterbin® is applied 1 or 2 times a day to the affected skin and adjacent areas. Apply the cream in a thin layer and rub in lightly. When applied to the area of ​​skin folds (groin area, intergluteal area, under the mammary glands), it is recommended to apply a gauze bandage/bandage.

Dermatomycosis of the trunk, large folds, legs:

1 time per day, duration of treatment - 1 week.

Ringworm of the feet:

1 time per day, duration of treatment - 1 week.

Skin candidiasis:

1-2 times a day, duration of treatment - 1-2 weeks;

Tinea versicolor:

1-2 times a day, duration of treatment - 1 week.

Spray

Externally.

The drug is applied to the skin 1 or 2 times a day. Before applying the spray, it is necessary to clean and dry the affected areas. The drug is sprayed onto the affected areas in an amount sufficient to thoroughly moisturize them, and, in addition, applied to adjacent areas of both affected and intact skin.

Average duration and frequency of use

Dermatomycosis of the trunk, legs:

1 week 1 time per day.

Ringworm of the feet:

1 week 1 time per day.

Skin candidiasis:

1–2 weeks 1 or 2 times a day.

Tinea versicolor:

1 week 1 or 2 times a day.

Experience with the use of Fungoterbin® spray in children is limited, and therefore its use in children under 12 years of age is not recommended.

Fungoterbin® Neo

Cream

Externally.

The drug is applied to the skin 1 or 2 times a day. Before applying the cream, it is necessary to clean and dry the affected areas. The cream is applied in a thin layer to the affected skin and lightly rubbed. To increase the effectiveness of treatment, it is possible to use occlusive dressings. For infections accompanied by diaper rash (under the mammary glands, in the spaces between the fingers, between the buttocks, in the groin area), the places where the cream is applied can be covered with gauze, especially at night.

The duration of treatment depends on the indication and severity of the disease.

Duration and frequency of use

Dermatomycosis of the trunk, legs:

1 time per day 1 week.

Ringworm of the feet:

1 time per day 1 week.

Skin candidiasis:

1 or 2 times a day for 1–2 weeks.

Tinea versicolor:

1 or 2 times a day for 2 weeks.

Gel

Externally.

The drug is applied to the skin 1 or 2 times a day. The gel is applied in a thin layer to the affected skin and lightly rubbed. To increase the effectiveness of treatment, it is possible to use occlusive dressings. For infections accompanied by diaper rash (under the mammary glands, in the spaces between the fingers, between the buttocks, in the groin area), the places where the gel is applied can be covered with gauze, especially at night.

Average duration and frequency of use

Dermatomycosis of the trunk, legs:

1 week 1 time per day.

Ringworm of the feet:

1 week 1 time per day.

Skin candidiasis:

1–2 weeks 1 or 2 times a day.

Tinea versicolor:

1 week 1 or 2 times a day.

Analogs

Level 4 ATX code matches:
Mikonorm

Undecin

Gentian violet

Zinkundan

Exoderil

Exiter

Batrafen

Lotseril

Lamisil Dermgel

Lamisil Uno

Lamisil

Salicylic acid

Salicylic ointment

Keto Plus

Exifin

Mycoseptin

Thermikon

Nitrofungin

Sulsena

Baziron AS

The closest analogues: Fungoterbin Neo, Binafin, Lamisil, Lamifast, Terbizil, Lamicon, Mikofin, Exifin, Atifin, Terbinafine, Terbix, Terbifin .

Fungoterbin price

The price of Fungoterbin tablets is 274 rubles for 10 tablets.

How much does the ointment cost? The price of Fungoterbin cream 1% (15 grams) is 250 rubles.

The cost of the spray is approximately 247 rubles per 30 ml.

  • Online pharmacies in RussiaRussia

ZdravCity

  • Fungoterbin cream 1% 15 gAO "Nizhpharm"
    RUR 342 order
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