What is Lazolvan
A medicine based on the active substance ambroxol hydrochloride. Designed to liquefy viscous mucous secretions and remove them from the lungs. The product is produced in several forms:
- inhalation solution: transparent light brown liquid containing 7.5 mg of ambroxol, in 100 ml bottles with dispensers and measuring cups;
- tablets for oral administration: round, yellowish, 30 mg each, in blisters with cells of 10 pcs.;
- children's syrup: viscous transparent liquid of a sweetish taste containing 15 mg of ambroxol, bottles of 100–200 ml;
- medicinal lozenges for resorption: brown, mint-scented, contain 15 mg of active ingredient.
Analogues: Ambrobene, Berodual
Most often, an analogy is drawn between medications such as:
- Ambrobene
- Berodual.
The difference between Lazolvan and Ambrobene is that they are produced by different manufacturers.
The birthplace of the first drug is Italy, but the second is Germany, but Lazolvan or Ambrobene for inhalation is better, you will have to decide for yourself. Exactly the same as when choosing Berodual, since which is better Lazolvan or Berodual for inhalation, as in the first case, can only be done by trying it. Ambrohexal solution is often recommended.
Recipes for inhalation with a runny nose using a nebulizer can be found at the link.
In addition, the analogue (substitute, replace) of Ambrobene has more release forms than Lazolvan. But after taking Ambromene, patients often experience side effects and many contraindications. As for Lazolvan, absolutely everyone can use it, even small children. This drug is well tolerated by the body.
How Lazolvan works
The medicine increases the volume and production of secretions, promoting its liquefaction, stimulates the work of epithelial cilia, helping to move phlegm out. The effect of aerosol particles of the drug begins 20–30 minutes after inhalation. After oral administration, the active substance begins to function within 2–3 hours.
The therapeutic effect lasts from 6 to 12 hours. The components of the drug are metabolized in the liver and leave the body within 10–15 hours. They do not accumulate in blood and tissues.
How to prepare a solution: ratio and proportions
It is known that the presented drug is actively used in the treatment of wet and dry cough using inhalation. To prepare a solution, you need to take x and send ½ of its contents into saline solution.
The resulting effect from inhalation of the solution lasts for 6-10 hours.
The proportion of Lazolvan and saline solution is 1:3. After this, the solution is sent to a nebulizer or other container for inhalation. Sometimes doctors prescribe a different dosage - 1:2 or 1:1. The role of saline solution is to achieve optimal humidification of the air in the respirator.
Read about inhalation for dry cough with a nebulizer in this article.
For what diseases is Lazolvan needed?
The medicine is indicated for use:
- for pneumonia;
- acute and chronic bronchitis;
- asthma with difficulty producing sputum;
- bronchial obstruction;
- respiratory distress syndrome;
- other pathologies of the respiratory tract, accompanied by excessive secretion synthesis.
Lazolvan improves well-being and makes breathing easier, but does not affect pathogens. It can only be used as a symptomatic remedy.
Action and ingredients: syrup, drops, tablets
Lazolvan is actively used in therapy for various pathologies, which are characterized by a wet cough with viscous sputum. Such diseases include:
- Chronical bronchitis;
- pneumonia;
- chronic lung disease;
- bronchial asthma;
- bronchiectasis.
We recommend reading about inhalations for laryngitis in this article.
Lazolvan is also actively used as a prophylactic agent and for the treatment of postpartum respiratory syndrome in infants and premature babies.
How to properly do inhalations for laryngitis with a nebulizer in this material.
Lazolvan belongs to the group of mucolytic drugs.
It contains ambroxol, which helps increase the secretion of mucus in the lungs. After this treatment, the patient’s symptoms of dry cough improve, sputum begins to be expectorated and its viscosity decreases.
If Lazolvan is used orally, a positive effect can be observed after 30 minutes. But the fastest results can only be achieved if the medicine is administered by injection.
But Lazolvan has its positive effect due to the components it contains. The main ingredient is ambroxol. Additional substances include sodium chloride, pure water and citric acid.
We recommend that you read about how to take chamomile for a cough.
How to use Lazolvan to treat children
For coughs and other respiratory tract lesions in children under 6 years of age, use the drug in syrup:
- children under 2 years of age: 2–2.5 ml twice a day;
- at 3–6 years: 3 ml, repeating the dose twice;
- from 6 to 12 years: 5 ml up to three times a day.
Adolescents over 12 years of age are allowed to consume 10 ml of syrup 2-3 times a day.
From the age of 6, you can give children lozenges: 1–2 pieces. three times a day. All forms of Lazolvan are compatible with food. Gastric juice does not affect the effect of the drug. During treatment, it is important to give your child plenty of fluids to drink. It is necessary for better separation of sputum.
Buy Lazolvan solution for internal use and for inhalation 7.5 mg/ml 100 ml in pharmacies
Brief description Lazolvan is a secretomotor, secretolytic, expectorant.
Pharmacological action Mucolytic and expectorant drug. Studies have shown that ambroxol, the active ingredient in Lazolvan®, increases secretion in the respiratory tract. Enhances the production of pulmonary surfactant and stimulates ciliary activity. These effects lead to increased mucus flow and transport (mucociliary clearance). Increasing mucociliary clearance improves sputum discharge and relieves cough. In patients with COPD, long-term therapy with Lazolvan® (for at least 2 months) led to a significant reduction in the number of exacerbations. There was a significant decrease in the duration of exacerbations and the number of days of antibiotic therapy.
Indications Acute and chronic diseases of the respiratory tract, accompanied by the release of viscous sputum and impaired mucociliary clearance: - acute and chronic bronchitis; - pneumonia; - COPD; - bronchial asthma with difficulty in sputum discharge; - bronchiectasis.
Directions for use and dosage: Oral administration (1 ml = 25 drops). Drops can be diluted in water, tea, juice or milk. The solution can be used regardless of meals. Adults and children over 12 years old - 4 ml (100 drops) 3 times a day; children aged 6 to 12 years - 2 ml (50 drops) 2-3 times a day; children aged 2 to 6 years - 1 ml (25 drops) 3 times a day; children under 2 years of age - 1 ml (25 drops) 2 times a day. Inhalations Adults and children over 6 years old - 1-2 inhalations of 2-3 ml of solution/day. Children under 6 years of age: 1-2 inhalations of 2 ml of solution/day. Lazolvan® solution for inhalation can be used using any modern equipment for inhalation (except steam inhalers). To achieve optimal hydration during inhalation, the drug is mixed with 0.9% sodium chloride solution in a 1:1 ratio. Since during inhalation therapy a deep breath can provoke a cough, inhalations should be carried out in normal breathing mode. Before inhalation, it is usually recommended to warm the inhalation solution to body temperature. Patients with bronchial asthma are recommended to carry out inhalation after taking bronchodilators to avoid nonspecific irritation of the respiratory tract and their spasm. If symptoms of the disease persist within 4-5 days from the start of using the drug, it is recommended to consult a doctor.
Side effects From the digestive system: often (1-10%) - dysgeusia (impaired sense of taste), nausea, decreased sensitivity in the oral cavity or pharynx; infrequently (0.1-1%) - dyspepsia, vomiting, diarrhea, abdominal pain, dry mouth; rarely (0.01-0.1%) - dry throat. From the skin and subcutaneous tissues: rarely (0.01-0.1%) - rash, itching*. Allergic reactions: rarely (0.01-0.1%) - urticaria; anaphylactic reactions (including anaphylactic shock)*, angioedema*, hypersensitivity*. * - these adverse reactions were observed with widespread use of the drug; with a 95% probability, the frequency of these adverse reactions is uncommon (0.1%-1%), but possibly lower; the exact frequency is difficult to estimate, because they were not noted in clinical studies.
Contraindications - first trimester of pregnancy; - lactation period (breastfeeding); - hypersensitivity to ambroxol or other components of the drug. Caution should be used in the second and third trimesters of pregnancy, in patients with renal and/or liver failure. Overdose Specific symptoms of overdose in humans have not been described. There have been reports of accidental overdose and/or medical error resulting in symptoms of known side effects of Lazolvan®: nausea, dyspepsia, vomiting, diarrhea, abdominal pain. Treatment: provocation of vomiting, gastric lavage in the first 1-2 hours after taking the drug, symptomatic therapy.
Special instructions Should not be used in combination with antitussives that impede the removal of sputum. The solution contains the preservative benzalkonium chloride, which, when inhaled, may cause bronchospasm in sensitive patients with increased respiratory tract reactivity. Lazolvan® solution for oral administration and inhalation is not recommended to be mixed with cromoglycic acid and alkaline solutions. An increase in the pH value of the solution above 6.3 may cause precipitation of ambroxol hydrochloride or the appearance of opalescence. Patients on a low-sodium diet should take into account that Lazolvan® solution for oral administration and inhalation contains 42.8 mg of sodium in the recommended daily dose (12 ml) for adults and children over 12 years of age. There are isolated reports of severe skin lesions (Stevens-Johnson syndrome and toxic epidermal necrolysis) that coincided with the use of expectorants such as ambroxol hydrochloride. In most cases, they are explained by the severity of the underlying disease and/or concomitant therapy. Patients with Stevens-Johnson syndrome or toxic epidermal necrolysis may present with fever, body aches, rhinitis, cough, and sore throat in the early phase. With symptomatic treatment, it is possible to erroneously prescribe anti-cold medications. If new lesions of the skin and mucous membranes develop, the patient should stop treatment with ambroxol and immediately seek medical help. If renal function is impaired, Lazolvan® should be used only on the recommendation of a doctor. Effect on the ability to drive vehicles and operate machinery. There were no cases of the drug influencing the ability to drive vehicles or operate machinery. Studies on the effect of the drug on the ability to drive vehicles and engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions have not been conducted.
Interaction with other drugs No clinically significant, undesirable interactions with other drugs have been reported. Ambroxol increases the penetration of amoxicillin, cefuroxime, and erythromycin into the bronchial secretions.
Storage conditions The drug should be stored out of the reach of children, protected from light at a temperature not exceeding 25°C. Shelf life: 5 years.
Video: instructions for using Lazolvan for an inhaler for a child
This video will tell you how to inhale Lazolvan to a child.
Lazolvan is an excellent medicine that helps overcome such a symptom of a cold as cough. Thanks to the natural components it contains, the drug is suitable for the treatment of cough in adults, children, infants and pregnant women. Only a doctor can determine the dosage (at what ratio/dose the drug should be diluted) and the method of application and use of Lazolvan; amateur activity in this case is not acceptable. Find out how to properly inhale saline solution when coughing here.
