pharmachologic effect
The drug is available with a prescription and is available in the form of ampoules for intravenous and intramuscular administration and an oral solution (disposable sachets or bottles). It and the analogue Ceraxon are based on a phospholipid precursor - citicoline. Has the following therapeutic effects:
- reduction of manifestations of amnesia;
- restoring damaged brain cells and preventing further death;
- reduces the volume of damaged tissue after strokes;
- reducing the duration of post-traumatic coma in traumatic brain injury (TBI);
- reduction of the recovery period and neurological manifestations after TBI;
- treatment of motor, sensory and cognitive (attention, memory) disorders;
- increasing indicators of consciousness and attention;
- combating difficulties in patients with self-care and performing simple functions, lack of initiative, memory impairment, forgetfulness;
- improving the quality of life in patients with vascular pathologies.
Recognan oral solution 100 mg/ml 10 ml N10 (Geropharm)
Clinical-pharmacological group: Nootropic drug Pharmaco-therapeutic group: Nootropic drug Pharmacological action Citicoline, being a precursor of key ultrastructural components of the cell membrane (mainly phospholipids), has a wide spectrum of action: promotes the restoration of damaged cell membranes, inhibits the action of phospholipases, preventing the excessive formation of free radicals , as well as preventing cell death by affecting the mechanisms of apoptosis. In the acute period of stroke, it reduces the volume of damaged tissue and improves cholinergic transmission. In case of traumatic brain injury, it reduces the duration of post-traumatic coma and the severity of neurological symptoms, in addition, it helps to reduce the duration of the recovery period. Citicoline is effective in the treatment of cognitive, sensory and motor neurological disorders of degenerative and vascular etiology. In chronic cerebral ischemia, citicoline is effective in treating disorders such as memory impairment, lack of initiative, and difficulties in performing daily activities and self-care. Increases the level of attention and consciousness, and also reduces the manifestation of amnesia. Pharmacokinetics Absorption Citicoline is well absorbed when taken orally. Absorption after oral administration is almost complete, and bioavailability is approximately the same as after intravenous administration. After oral and parenteral administration, the concentration of choline in the blood plasma increases significantly. Distribution Citicoline is widely distributed in brain structures, with rapid incorporation of choline fractions into structural phospholipids and cytidine fractions into cytidine nucleotides and nucleic acids. Citicoline penetrates the brain and is actively incorporated into cellular, cytoplasmic and mitochondrial membranes, forming part of the fraction of structural phospholipids. Metabolism When administered intravenously and intramuscularly, citicoline is metabolized in the liver to form choline and cytidine. Excretion Only 15% of the administered dose of citicoline is excreted from the human body: less than 3% by the kidneys and intestines and about 12% by exhaled air. The excretion of citicoline in urine can be divided into 2 phases: a first phase, lasting about 36 hours, during which the rate of excretion decreases rapidly, and a second phase, during which the rate of excretion decreases much more slowly. The same is observed in exhaled air - the rate of elimination decreases rapidly after approximately 15 hours and then decreases much more slowly.
Indications for use of Recognan
Recognan and analogues (Cerakson, Gliatilin and others) are prescribed in the form of ampoules or oral solution depending on the severity of the condition, indications, age of the patient and other characteristics:
- treatment of TBI in the acute and recovery period, reducing the risk of neurological symptoms;
- recovery and acute period of strokes (in particular, ischemic and hemorrhagic);
- treatment of behavioral abnormalities, decreased memory, memorization, attention, the ability to perform simple functions during self-care, mainly in older people, people with vascular and degenerative diseases of the brain.
Recognan
Nootropic drug. Citicoline, being a precursor of key ultrastructural components of the cell membrane (mainly phospholipids), has a wide spectrum of action: it promotes the restoration of damaged cell membranes, inhibits the action of phospholipases, preventing the excessive formation of free radicals, and also preventing cell death by affecting the mechanisms of apoptosis.
In the acute period of stroke, it reduces the volume of damaged tissue and improves cholinergic transmission.
In case of traumatic brain injury, it reduces the duration of post-traumatic coma and the severity of neurological symptoms, in addition, it helps to reduce the duration of the recovery period.
Citicoline improves the symptoms observed during hypoxia: memory impairment, emotional lability, lack of initiative, difficulties in performing daily activities and self-care. Effective in the treatment of cognitive, sensory and motor neurological disorders of degenerative and vascular etiology.
In chronic cerebral ischemia, citicoline is effective in treating disorders such as memory impairment, lack of initiative, and difficulties in performing daily activities and self-care. Increases the level of attention and consciousness, and also reduces the manifestation of amnesia.
Pharmacokinetics
Suction
Citicoline is well absorbed when taken orally. Absorption after oral administration is almost complete, and bioavailability is approximately the same as after intravenous administration.
Distribution
Citicoline is widely distributed in brain structures, with rapid incorporation of choline fractions into structural phospholipids and cytidine fractions into cytidine nucleotides and nucleic acids. Citicoline penetrates into the brain and is actively integrated into cellular, cytoplasmic and mitochondrial membranes, forming part of the fraction of structural phospholipids
Metabolism
After oral administration, the drug is metabolized in the intestines and liver with the formation of choline and cytidine.
With IV and IM administration, citicoline is metabolized in the liver to form choline and cytidine.
After oral or parenteral (IV, IM) administration, the concentration of choline in the blood plasma increases significantly.
Removal
Only 15% of the administered dose of citicoline is excreted from the human body: less than 3% by the kidneys and through the intestines and about 12% by exhaled air.
The excretion of citicoline in urine can be divided into 2 phases: a first phase, lasting about 36 hours, during which the rate of excretion decreases rapidly, and a second phase, during which the rate of excretion decreases much more slowly. The same is observed in exhaled air - the rate of elimination decreases rapidly after approximately 15 hours and then decreases much more slowly.
Recognan - instructions for use
Before using the drug, it is important to consult a doctor, study the information about Recognan (instructions for use), possible limitations and features of the medication.
Note! The most effective and powerful form of release is ampoules used intravenously. In this case, it is important not to hit the same place when injecting.
The dosage and release form are selected by the doctor individually. It is possible to combine several forms for a stable, quick effect: after intravenous or intramuscular injections, start long-term oral administration of Recognan or analogues.
The solution, created for oral administration, is diluted in a small amount of water (half a glass) and drunk during meals or between meals. The frequency of use is individual: 1–2 times a day, the course lasts up to 6 weeks or more.
After using the medication, undesirable, transient reactions may occur. If they become stronger, you must inform your doctor:
- allergic manifestations;
- shortness of breath, swelling, feeling of heat (especially after injection forms immediately after administration);
- diarrhea, vomiting, nausea;
- dizziness, headache;
- short-term change in blood pressure.
Recognan and the analogue Ceraxon are not used in childhood, pregnancy and lactation due to insufficient knowledge of the effects on these individuals, possible benefits and harm.
Buy Recognan solution intravenously and intramuscularly 1000 mg/4 ml ampoules 4 ml No. 5 in pharmacies
MINISTRY OF HEALTH OF THE RUSSIAN FEDERATION
INSTRUCTIONS FOR USE OF THE MEDICINE FOR MEDICAL USE
RECOGNAN®
Read these instructions carefully before you start taking/using this medicine. Save the instructions, you may need them again. If you have any questions, consult your doctor. This medicine is prescribed for you personally and should not be given to others because it may harm them even if they have the same symptoms as you.
Trade name : RECOGNAN®
International nonproprietary name : Citicoline
Dosage form: Solution for intravenous and intramuscular administration
Composition One ampoule of 500 mg in 4 ml contains the active substance: citicoline monosodium salt (citicoline sodium) 522.5 mg (equivalent to 500.0 mg of citicoline), excipients: hydrochloric acid or sodium hydroxide to pH 6.5 - 7.5; water for injection up to 4.0 ml.
One ampoule of 1000 mg in 4 ml contains the active substance: citicoline monosodium salt (citicoline sodium) 1045.0 mg (equivalent to 1000.0 mg citicoline) excipients: hydrochloric acid or sodium hydroxide to pH 6.5 - 7.5; water for injection up to 4.0 ml.
Description Transparent colorless liquid
Pharmacotherapeutic group: nootropic agent
ATX code: N06BX06
Pharmacological properties Pharmacodynamics Citicoline, being a precursor of key ultrastructural components of the cell membrane (mainly phospholipids), has a wide spectrum of action - it promotes the restoration of damaged cell membranes, inhibits the action of phospholipases, preventing the excessive formation of free radicals, and also preventing cell death by affecting the mechanisms of apoptosis. In the acute period of stroke, citicoline reduces the volume of brain tissue damage and improves cholinergic transmission. In case of traumatic brain injury, it reduces the duration of post-traumatic coma and the severity of neurological symptoms, in addition, it helps to reduce the duration of the recovery period. Citicoline is effective in the treatment of cognitive, sensory and motor neurological disorders of degenerative and vascular etiology. In chronic cerebral ischemia, citicoline is effective in treating disorders such as memory impairment, lack of initiative, and difficulties in performing daily activities and self-care. Increases the level of attention and consciousness, and also reduces the manifestation of amnesia.
Pharmacokinetics Metabolism When administered intravenously and intramuscularly, citicoline is metabolized in the liver to form choline and cytidine. After administration, the concentration of choline in the blood plasma increases significantly. Distribution Citicoline is widely distributed in brain structures, with rapid incorporation of choline fractions into structural phospholipids and cytidine fractions into cytidine nucleotides and nucleic acids. Citicoline penetrates the brain and is actively incorporated into cellular, cytoplasmic and mitochondrial membranes, forming part of the fraction of structural phospholipids. Excretion Only 15% of the administered dose of citicoline is excreted from the human body: less than 3% by the kidneys and intestines and about 12% by exhaled air. The excretion of citicoline in urine can be divided into 2 phases: a first phase, lasting about 36 hours, during which the rate of excretion decreases rapidly, and a second phase, during which the rate of excretion decreases much more slowly. The same is observed in exhaled air - the rate of elimination decreases rapidly after about 15 hours, and then decreases much more slowly.
Indications for use Acute period of ischemic stroke (as part of complex therapy), Recovery period of ischemic and hemorrhagic strokes, Traumatic brain injury (TBI), acute (as part of complex therapy) and recovery period, Cognitive and behavioral disorders in degenerative and vascular diseases of the brain brain
Contraindications It should not be prescribed to patients with vagotonia (predominance of the tone of the parasympathetic part of the autonomic nervous system) or with hypersensitivity to any of the components of the drug. Due to the lack of sufficient clinical data, it is not recommended for use in children under 18 years of age.
Use during pregnancy and breastfeeding There are no sufficient data on the use of citicoline in pregnant women. Although animal studies have not revealed any negative effects, during pregnancy the drug Recognan ® is prescribed only in cases where the expected benefit to the mother outweighs the potential risk to the fetus. When prescribing Recognan® during lactation, women should stop breastfeeding, since there is no data on the excretion of citicoline in human milk.
Method of administration and dosage The drug is prescribed intravenously or intramuscularly. Intravenously is prescribed in the form of a slow intravenous injection (over 3-5 minutes, depending on the prescribed dose) or intravenous drip (4060 drops per minute). The intravenous route of administration is preferable to the intramuscular route. When administered intramuscularly, repeated administration of the drug in the same place should be avoided. Recommended dosage regimen Acute period of ischemic stroke and traumatic brain injury (TBI): 1000 mg every 12 hours from the first day after diagnosis. The duration of treatment is at least 6 weeks. 3-5 days after the start of treatment (if swallowing function is not impaired), it is possible to switch to oral forms of the drug Recognan®. Recovery period of ischemic and hemorrhagic strokes, recovery period of head injury, cognitive and behavioral disorders in degenerative and vascular diseases of the brain: 500-2000 mg per day. Dosage and duration of treatment depending on the severity of the symptoms of the disease. It is possible to use oral forms of the drug Recognan®. Elderly patients: When prescribing Recognan® to elderly patients, no correction is required. The solution in the ampoule is intended for single use. It must be used immediately after opening the ampoule. The drug is compatible with all types of intravenous isotonic solutions and dextrose solutions.
Side effect Frequency of adverse reactions Very rare (<1/10000) (including individual cases): Allergic reactions (rash, itching, anaphylactic shock), headache, dizziness, feeling of heat, tremor, nausea, vomiting, diarrhea, hallucinations, swelling , shortness of breath, insomnia, agitation, loss of appetite, numbness in paralyzed limbs, changes in the activity of liver enzymes. In some cases, the drug can stimulate the parasympathetic system and also temporarily change blood pressure. If any of the side effects indicated in the instructions get worse, or any other side effects not listed in the instructions are noticed, you should inform your doctor.
Overdose Given the low toxicity of the drug, cases of overdose have not been described.
Interaction with other drugs Citicoline enhances the effects of levodopa. Should not be administered concomitantly with medicinal products containing meclofenoxate.
Special instructions Impact on the ability to drive vehicles and machinery During the treatment period, care should be taken when performing potentially hazardous activities that require increased special attention and speed of psychomotor reactions (driving a car and other vehicles, working with moving mechanisms, working as a dispatcher, operator, etc.) .P.).
Release forms Solution for intravenous and intramuscular administration 500 mg/4 ml, 1000 mg/4 ml. 4.0 ml in colorless glass ampoules of neutral glass (hydrolytic class I) with a stripe or break point. 5 ampoules per blister pack made of polyvinyl chloride film or polyvinyl chloride film and aluminum foil. One or two contour packages with instructions for use are placed in a box made of cardboard.
Storage conditions Store at a temperature not exceeding 25 0C. Keep out of the reach of children.
Shelf life: 3 years. Do not use after the expiration date indicated on the package.
Conditions of release Prescription release
Manufacturer 1. ALPHA WASSERMANN S.p.A., Italy, Pescara 2. FSUE "Moscow Endocrine Plant", Russia
Address of the manufacturer/place of production 1. 65020, Alanno Scano (Pescara), Via Enrico Fermi 1 2. 109052, Moscow, st. Novokhokhlovsksya, 25, building 1, building 2
Legal entity in whose name the registration certificate was issued/ Organization accepting claims GEROPHARM LLC, Russian Federation Legal address: 191119 St. Petersburg, st. Zvenigorodskaya, 9 Postal address: 191114, St. Petersburg, Degtyarny Lane, 11, lit. B Telephone (multi-channel), fax: (812) 103-79-76 Hotline telephone: 8-800-333-4376 (calls within Russia are free) www.geropharm.ru [email protected]
Recognan's analogs
Pharmacies offer analogues of Recognan based on the active substance:
- Ceraxon;
- Gliatilin;
- Naypilept;
- Neurocholine;
- Encetron;
- Proneuro;
- Citicoline, etc.
They differ in release form, bottle size for internal use, price, country of origin, supplier, degree of purification of raw materials, and technologies used. Imported analogues of the drug Recognan (Cerakson) have been studied and clinically tested on various categories of people and animals.
Prices for Recognan and analogues in Moscow. In regions, the cost may vary slightly.
A drug | Release form | Price , in rubles | Manufacturer country |
Recognan | sachet No. 10 | 1200-1450 | Russia/Spain |
ampoules 500 mg | 450-600 | Russia/Italy | |
ampoules 1000 mg | 830-970 | ||
bottle 30 ml | 370-500 | ||
Vinpotropil | capsules and tablets No. 30 | 150-250 | Russia |
№60 | 240-450 | ||
Cortexin | 5 mg vials | 750-900 | Russia |
10 mg | 1200-1450 | ||
Gliatilin | ampoules No. 3 | 540-670 | Italy |
capsules No. 14 | 750-900 | ||
Cerakson | ampoules 500 mg | 590-670 | Spain |
1000 mg | 970-1100 | ||
bottle 30 ml | 700-820 | ||
sachet | 1350-1500 | ||
Naypilept | solution 30 ml | 330-430 | Russia |
100 ml | 870-1100 | ||
ampoules 500 mg | 400-520 | ||
1000 mg | 700-830 | ||
Cavinton | tablets 5 mg | 210-260 | Hungary |
ampoules | 200-360 | ||
Cavinton forte | tablets 10 mg | 270-750 | |
comfort 10 mg | 240-600 | ||
Cerepro | ampoules No. 5 | 450-600 | Russia |
capsules No. 28 | 830-1000 |
Naypilept
Neupilept forms are cheap analogues of Recognan, produced in Russia. The cost of the medicine is 20% lower. A significant difference is that the manufacturer does not produce the medication for oral administration in the form of a sachet. A good and cost-effective alternative is a large 100 ml bottle, which is 40-50% lower than Recognan bags.
When choosing between Recognan or Neypilept, you can choose any analogue that is affordable. Both medications are produced by Russian pharmaceutical companies and differ in cost, supplier of raw materials, production technologies and excipients in the composition. The main substance that provides therapeutic effects is the same in Recognan and its analogue.
Cavinton
Hungarian drug for infusion and oral administration in the form of tablets with a dosage of 5 mg. The company also produces a strengthened formula of Cavinton Forte and tablets for active people or patients with swallowing difficulties. The latter form can be absorbed, the effect is achieved faster, and another advantage is the lower price.
The analogue improves metabolic or metabolic processes in the brain, increases blood supply to the affected areas, relieves patients from tinnitus, dizziness, and unsteadiness in gait. The recommended dose is 10 mg up to 3 times a day.
Cerepro
The Russian substitute is cheaper and is available in ampoules and capsules for long-term oral use. The therapeutic effects of the analogue are based on the substance included in the composition - choline alfoscerate. The analogue is prescribed for head injury, cognitive disorders, vascular disorders in elderly patients, and chronic cerebral circulatory failure. Has positive reviews from neurologists. Improves brain functionality, increases behavioral and cognitive reactions (memory, attention) in people with brain disorders and pathologies.
Vinpotropil
A combined analogue based on two components - vinpocetine and piracetam in the form of ampoules, tablets and capsules. Thanks to its complex composition, the medication improves cerebral circulation, slightly lowers blood pressure, and increases mental performance. Taken in periodic courses for up to 3 months, preferably in spring and autumn. Also prescribed for tinnitus and dizziness due to pathologies of the vascular system.
Cortexin
Analogue for injection use from polypeptides of the cerebral cortex of livestock. Indications for the drug are the same as for Recognan: impaired cerebral circulation, consequences of head injury, cognitive impairment. It is also used in children’s practice for speech delay and psychomotor development.
Nootropic drug Geropharm Recognan - reviews
RIMM
https://otzyvy.pro/reviews/otzyvy-rekognan-183290.html
The doctor prescribed Recognan because of psycho-emotional stress: I was working and studying at the same time, and somehow everything came together. I took the prescribed course and probably felt improvements towards the end of the first week of taking it. The condition changed just before our eyes. A good drug, but take it, of course, after consulting a doctor and strictly according to indications.
Nyusha
https://ru.otzyv.com/rekognan
After the injury, memory problems also began. Nootropics in this case are of course a salvation, various medications were prescribed, but Recognan is best suited, plus it is convenient to drink and the course is the simplest.
Marya
https://ru.otzyv.com/rekognan
I don’t see any difference between these drugs, so I act on the principle that if the effect is the same, why pay more? I take Recognan, it helps me well.
Lisa
https://www.otzyvua.net/rekognan.html
I drink Recognan, it contains the active ingredient citicoline, it works gently but is very effective. I feel a surge of strength, activity, improved memory. I’m as focused as possible, I get a lot done, I’m less tired and nervous - I really like this effect.
Vlad
https://otzyvy.pro/reviews/otzyvy-rekognan-183290.html
For a student (especially during a session), nootropics are a salvation, which is why I buy Recognan. With him, the brain really clears up and begins to think better.
Elena_Recommends
https://irecommend.ru/content/moi-otzyv-o-rekognane-io-tom-kak-vernul-mne-sily
When I started having memory problems, I decided that I was just tired. When the situation began to worsen, I went to the doctor, where they told me that my cerebral circulation was impaired. I’ll tell you this, if you see that you’ve begun to think poorly, you’ve become slow, you constantly have a loss of strength, don’t expect it to go away on its own. It may not pass! It definitely wouldn’t go away for me, but it would only get worse. In general, the doctor made a diagnosis and prescribed treatment, which included nootropics on the list. The word nootropic itself sounds scary, but, in essence, these drugs help our brain work better. I was prescribed Recognan, which is a nootropic containing citicoline.
Recognan is an expensive drug, but I’m used to the fact that good drugs cannot be cheap. Recognan is available in sachets, each containing 10 ml of solution, ready for use.
The solution can be drunk immediately, or it can be diluted with water and taken in diluted form.
In both cases, the drug is taken without problems, and the taste is quite tolerable (strawberry). I took it once a day, as prescribed. The course is not difficult, the results are gradual, and most importantly, long-lasting. Now my memory works well, I concentrate easily, my performance is excellent and I don’t suffer from stress. Even after stopping taking the drug, the result is still there.
PS/ Nootropics are not prescribed for nothing, so you should always consult a doctor before using them.
Svetlana Uspechna
https://otzovik.com/review_7602649.html
Advantages:
There is improvement after treatment
Flaws:
A bit expensive
Recognan injections were prescribed to my mother by a neurologist. The course of treatment is 10 days. There are 5 ampoules of 4 ml in a box. You will need 2 boxes for a course of treatment. All this cost 2048 rubles. A little expensive, but worth buying. Mom felt better, but during treatment there was skin itching for 2 days. This is indicated in the instructions that there may be an allergic reaction. There were no other side effects. I recommend Recognan because my mother’s condition has improved: her attention has increased and her memory has improved. I would also like to note that during treatment you should lead a calm lifestyle and not physically strain yourself. This is also mentioned in the instructions: be careful when performing hazardous activities.
Faith
https://otzyvy.pro/reviews/otzyvy-rekognan-183290.html
Thanks to Recognan, I passed the test with flying colors. Everything became so overwhelming that my head stopped working completely. Everything I study and read flies past my head, but nothing lingers at all. There is “jelly” in the head in the full sense of the word. I went to the doctor to consult about nootropics. He prescribed Recognan. Within a week the situation changed for the better. I passed the session perfectly, and my brain fell into place)) It’s a good drug, but you can only buy it with a prescription and in online pharmacies.
marialunegova
https://irecommend.ru/content/sposoben-vernut-k-polnotsennoi-zhizni
Not long ago I started having health problems. My left hand began to go numb and I felt a tingling sensation. I contacted a neurologist and even had to go to the hospital for examination. And when I was discharged, they recommended that I take Ceraxon for 3 months.
I calculated the cost - I had to pay 15 thousand for all this! But a doctor I know recommended an analogue of Ceraxon - Recognan.
I was confused by the fact that it is made in Russia, well, I don’t trust Russian medicines! But they considered the benefits and decided.
The very first doses of Recognan showed that this drug is not inferior to Ceraxon at all, supporting the body in the same way! I began to feel much better after the first 2-3 uses! And, you know, this is real happiness!
In addition, we really saved money: in 3 months of treatment we spent about 9.5 thousand rubles! The difference is obvious - 5 thousand.
The drug is available in a bottle in the form of a liquid, or in separate sachets - and this, it seems to us, is very convenient.
In general, I recommend it to everyone!
Lucky-Smile
https://otzovik.com/review_9985694.html
Advantages:
Availability, clinically proven effectiveness
Flaws:
Side effects, price
Good day, dear readers! The neurologist prescribed a rather serious drug for my daughter, Recognan, since she is 2 years old and does not speak. The drug has clinical effectiveness, but after 18 years and is aimed at improving brain performance. I took it in liquid form with a measuring syringe, it’s very convenient for us, transparent, slightly sweet in taste. This “pleasure” costs around 1000 rubles, this bottle should be enough for us for a month, but the course was prescribed for 2 months. Unfortunately, we have side effects - tearfulness, poor appetite, but I hope it’s not in vain and this drug will help us. If there are side effects, then there must be an effective result. Summarizing all of the above, I still recommend purchasing it AS PRESCRIBED BY A DOCTOR. Thank you for your attention to my review, Your Lucky_Smile.
Chepus
https://otzovik.com/review_7401530.html
Advantages:
900 rubles for 5 injections, fairly quick effect
Flaws:
cannot be placed in the afternoon.
I take a course of nootropics/vascular drugs once a year. This year the hospital prescribed Recognan. Based on the domestic manufacturer, one might think that the product is ineffective. I thought so myself at the beginning of the therapy, but no - there is an effect, after the 3rd injection my head became clearer, but there was also a little anxiety. I do not exclude that this is possible due to simultaneous therapy with pentoxifylline. Or there may be an insufficiently pronounced effect due to intramuscular use. The price is not much cheaper than Ceraxon. I think there is no point in saving if Cerakson suits you. Apparently, I was lucky - both drugs are suitable. In general, I recommend it - the drug works well and justifies the described indications for use.
Marina2979
https://irecommend.ru/content/ne-khuzhe-tseraksona
This is not the first time I have taken Recognan. I switched to it from Ceraxon when it was not available in the pharmacy and I think that this transition was very successful.
Recognan is available in sachets, each of which contains a single dose of the drug. One sachet contains 10 ml of solution. There are 10 sachets in one package. Active ingredient: citicoline, dosage 100 mg/ml. I take 1 sachet once a day, that’s enough for me. When I have time to tinker, I dissolve the contents of the bag in 1/2 glass of water and drink it. The taste of the drug is pleasant, sweet, not disgusting. Although there is no difference in the active ingredient and dosage, there is a difference in sensations and side effects. On Recognan there are no problems with sleep, no overexcitation, all reactions are smooth. With the original it was a little worse, I couldn’t sleep, plus after the course there was a setback, which I didn’t like either.
During treatment, of course, there are positive changes, for example, you become more focused, attentive, and balanced. After finishing taking the drug, the result also remains, which is important. I had a chance to try a lot of nootropics and have something to compare with, so I realized for myself that Recognan was the best option.
Karavaeva Natalya
https://irecommend.ru/content/realno-deistvennoe-sredstvo-uluchshayushchee-rabotu-mozga
The drug "Recognan" is an oral medication that improves brain function.
Pharmacotherapeutic group: nootropic agent.
I take this drug to improve memory and cerebral circulation. For many years I have been suffering from migraine-like headaches; after examination, I was diagnosed with a cerebrovascular accident due to congenital narrowing of the carotid artery. At a young age, I did not complain about my memory, but now I began to notice that it began to decline and remembering something was becoming more difficult. In addition, periodic dizziness and drowsiness occurred, and visual acuity began to deteriorate. I began to react sensitively with headaches to weather changes.
To stop these symptoms, I found this drug and began taking it 3 ml per day every day. Within a couple of days I noticed an improvement. Efficiency and vigor appeared, as if out of a fog - the clarity of thinking was simply pleasing. For the first time in a long time, I did not react to a sudden change in weather from above-zero to below-zero temperatures. Intense headaches that were resistant to painkillers have subsided, which is good news. I plan to take this drug in courses and repeat them every quarter for now, and then, perhaps, I will no longer need to do this.
The product is very easy to use - it comes in a bottle and has a transparent color. A measuring syringe is included with the product. I take the amount of product I need from the bottle and dissolve it in a quarter glass of boiled water, and then drink it. The taste is vaguely reminiscent of strawberries, so there is no need to wash down the medicine with anything.
Recognan helped me and I am very happy about it. I did not find any side effects, and the positive results were obvious. Before using this medicine, you should read the instructions and consult with your doctor. There are contraindications.
Klava71
https://irecommend.ru/content/preparat-stoit-svoikh-deneg
Hello, I want to tell you about the modern nootropic drug Recognan. I was diagnosed with multiple sclerosis. In addition to all the symptoms, one of the most pronounced was cognitive pathology. Serious memory problems greatly interfered with everyday life. I could forget a bag of groceries in the store, turn off the gas, iron, water. I was afraid to stay at home alone, something irreparable could happen. The neurologist prescribed Recognan and Neurobion vitamins. After a month of treatment, my memory has noticeably improved. I can’t say that I don’t forget anything, but I began to remember what I did. This is great progress. I come home from the store with some shopping, remember that I forgot the package and come back! She didn’t burn the kettle, she also caught it in time. Although multiple sclerosis is an incurable disease, it can be alleviated with the help of medications. Recognan contains citicoline, a component of the cell membrane, it helps restore brain cells. Increases attention and reduces irritability. I bought this medicine in sachet form, small sealed bags, easy to open and use. You can immediately put the contents into your mouth or dilute it with water, as you like. The drug is wonderful, I will continue to be treated.
Zhanna
https://www.otzyvru.com/rekognan
My grandmother takes Recognan; due to her old age, she has poor memory and attention span. So the neurologist discharged him. A very convenient once-a-day regimen; these are not tablets, but a solution in an individual sachet. Grandma doesn’t miss an appointment, there is a result. She remembers more and feels better.
Lisa
https://www.otzyvru.com/rekognan
Of all the noorops, I like Recognan for its mild action and good results. Helps your head turn on and start working better. It’s also easy to take and has a pleasant taste.
Solnishk0
https://irecommend.ru/content/otlichnyi-preparat-173
For the second year now I have been trying to combine work and study at the institute. This year has been more difficult in all directions, I’m probably tired. It’s hard to remember large volumes, I’m very absent-minded, I can’t concentrate, in general, I have no strength for anything. I went to the doctor, hoping that they would prescribe me vitamins and that they would help. But the doctor had a different opinion on this matter, she said that the problem will not be solved just like that, it is more effective to take a course of the nootropic Recognan, take it once a day, but this is no longer just taking vitamins. After thinking about it, I decided to undergo a course of treatment, it was very important to improve my memory, to unlearn it efficiently, not just for show. In fact, nootropics improve blood circulation in the head and the condition of blood vessels. Which gives the memory more room to work. The result was assessed after several weeks of taking the nootropic. My head has really begun to work faster, I can easily remember new information, I can understand, think, and react faster. The result is very good! Having received it, I decided to further pump up my memory, now I do exercises every day to train my brain. Of course, nothing would have worked without good blood circulation in the head. Therefore, the solution to the issue must always be comprehensive and nothing else.
Recognan or Cerakson - which is better?
Ceraxon is an imported original drug based on citicoline (Spain), available in ampoules, a solution for internal use in disposable sachets and a 30 ml bottle.
When choosing between Ceraxon or Recognan, if you have the necessary funds, it is better to choose the first drug. It was he who was studied on categories of patients, during the course of which undesirable reactions were identified, and detailed instructions were drawn up.
Recognan uses different production technologies and excipients, which may affect the incidence of side effects.
The price of the analogue Ceraxon is approximately 15-20% higher compared to Recognan.
Gliatilin or Recognan - which is better?
Gliatilin is an original drug based on choline alfoscerate, offered in pharmacies in capsules and ampoules. Its analogue for the active substance is Cerepro. It allows you to restore and improve brain function, overcome cognitive and behavioral disorders.
In terms of their action, Recognan and Gliatilin are almost identical, they have similar indications and restrictions for use. The difference is in price, active ingredient, and manufacturer. Both drugs have proven themselves among doctors and patients. The choice in favor of one or the other should be made by the doctor based on the individual characteristics of the patient.
Recognan is a prescription drug for cerebral blood vessels. It is preferable to replace it with analogues (Cerakson, Gliatilin, etc.) with a neurologist, neurologist or therapist.
Recognan, 1000 mg/4 ml, solution for intravenous and intramuscular administration, 4 ml, 5 pcs.
Clinical and pharmacological group: Nootropic drug
Pharmacotherapeutic group: Nootropic drug
pharmachologic effect
Citicoline, being a precursor of key ultrastructural components of the cell membrane (mainly phospholipids), has a wide spectrum of action: it promotes the restoration of damaged cell membranes, inhibits the action of phospholipases, preventing the excessive formation of free radicals, and also preventing cell death by affecting the mechanisms of apoptosis.
In the acute period of stroke, it reduces the volume of damaged tissue and improves cholinergic transmission.
In case of traumatic brain injury, it reduces the duration of post-traumatic coma and the severity of neurological symptoms, in addition, it helps to reduce the duration of the recovery period.
Citicoline is effective in the treatment of cognitive, sensory and motor neurological disorders of degenerative and vascular etiology.
In chronic cerebral ischemia, citicoline is effective in treating disorders such as memory impairment, lack of initiative, and difficulties in performing daily activities and self-care. Increases the level of attention and consciousness, and also reduces the manifestation of amnesia.
Pharmacokinetics
Suction
Citicoline is well absorbed when taken orally. Absorption after oral administration is almost complete, and bioavailability is approximately the same as after intravenous administration. After oral and parenteral administration, the concentration of choline in the blood plasma increases significantly.
Distribution
Citicoline is widely distributed in brain structures, with rapid incorporation of choline fractions into structural phospholipids and cytidine fractions into cytidine nucleotides and nucleic acids. Citicoline penetrates the brain and is actively incorporated into cellular, cytoplasmic and mitochondrial membranes, forming part of the fraction of structural phospholipids.
Metabolism
With IV and IM administration, citicoline is metabolized in the liver to form choline and cytidine.
Removal
Only 15% of the administered dose of citicoline is excreted from the human body: less than 3% by the kidneys and through the intestines and about 12% by exhaled air.
The excretion of citicoline in urine can be divided into 2 phases: a first phase, lasting about 36 hours, during which the rate of excretion decreases rapidly, and a second phase, during which the rate of excretion decreases much more slowly. The same is observed in exhaled air - the rate of elimination decreases rapidly after approximately 15 hours and then decreases much more slowly.