Normobakt por for internal solution 2g plus 3.89g sachet N8 aquabalance

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

The main active ingredient of the drug, lactulose, is a synthetic derivative of lactose. It is practically not absorbed in the stomach and small intestine due to the lack of necessary enzymes. In the large intestine, its breakdown into low molecular weight organic acids occurs under the influence of intestinal microflora, as a result of which the pH and the osmotic pressure increases, which stimulates intestinal motility. As a result of this, the consistency of stool is normalized and its volume increases, which normalizes the process of defecation and intestinal function in general.

The drug stimulates the growth of bifidobacteria , while the process of development of pathological microflora in the large intestine is inhibited and intoxication by their waste products is reduced, since the bacteria of the large intestine in the presence of lactulose do not decompose amino acids , which reduces the accumulation of toxic products of protein decomposition. Normolact inhibits the growth and development of salmonella in the colon.

The drug is not addictive and does not reduce the absorption of vitamins . The effect of the drug occurs 1-2 days after taking it, which is due to the duration of the process of lactulose through the gastrointestinal tract .

Pharmacokinetics

Lactulose, when ingested, passes into the large intestine, where bacteria that break down sugar metabolize it mainly to lactic acid and, to a lesser extent, to formic and acetic acids. The components of lactulose are practically not absorbed into the blood and are excreted in small quantities through the kidneys.

Normobact - L powder sachet 3g No. 10 for children from 1 month

Compound

For 1 sachet (3 g): maltodextrin, lyophilized lactic acid bacteria Lactobacillus rhamnosus GG - 4×109 CFU, fructooligosaccharides, mono- and diglycerides of fatty acids (E471) - a substance that prevents caking.

Indications for use

As a biologically active food supplement - a source of probiotic microorganisms and fructooligosaccharides that contribute to:

• improving bowel function;
• restoring the balance of intestinal microflora;
• strengthening the immune system and accelerating the body’s adaptation processes.

Possible applications:

• taking antibiotics;
• intestinal infections and poisoning;
• stool disorders (diarrhea, constipation);
• food allergies, atopic dermatitis;
• change of diet and diet (travel);
• decrease in the body's defenses;
• imbalance of microflora.

Contraindications

Individual intolerance to dietary supplement components

Directions for use and doses

Take orally during meals, immediately after dissolution in liquid.

Infants over 1 month and children under 3 years of age are prescribed 1 sachet/day. For children under 3 years of age, the contents of the sachet should be dissolved in a sufficient amount of liquid before use; For breastfed children, the contents of the sachet should be dissolved in expressed breast milk before use.

Children over 3 years of age and adults are prescribed 1-2 sachets/day. The contents of the sachet should be dissolved in water, yogurt or milk before use.

Do not exceed the recommended daily dose.

The average duration of use is 10-14 days. During and after the end of antibiotic treatment, the duration of use of Normobact L can be 2-3 weeks.

Storage conditions

Store in a dry place, protected from light, at a temperature not exceeding 25°C. Keep out of the reach of children.

Best before date

2 years. Do not use after the expiration date stated on the packaging.

special instructions

A dietary supplement to food, it is not a medicine.

Before use, you should consult your doctor.

Normobact L is not intended for parenteral use.

Normobact L has not been treated with ionizing radiation.

In the dietary supplement Normobakt L, the Lactobacillus rhamnosus GG (LGG®) strain is of natural origin and is not subject to any genetic changes.

Normobakt L does not contain cow's milk proteins, lactose, gluten and sucrose, so it can be used in people who are intolerant to these substances.

Normobact L should not be used as the main source of nutrition.

Description

Dietary supplement - synbiotic (probiotic + prebiotic).

Action

Normobact L is a biologically active food supplement that combines probiotics (live lactic acid bacteria Lactobacillus rhamnosus GG) and prebiotics (fructooligosaccharides). This combination prolongs the life of “good” bacteria and significantly increases their number in the intestines; restores the body's immune resistance.

Fructooligosaccharides (prebiotics) are dietary fibers that belong to the class of low-calorie indigestible carbohydrates. Necessary for normal intestinal function and are a source of nutrition for intestinal microflora.

Maltodextrin is a product of incomplete hydrolysis of starch and is non-toxic. It is an auxiliary component of the dietary supplement Normobakt L, neutral for the baby’s digestion.

Mono- and diglycerides of fatty acids (E471) are a food additive of natural origin, classified as harmless. Widely used as a stabilizer and emulsifier in the production of baby food, confectionery and baking.

LGG® - Lactobacillus rhamnosus, isolated by Professors Gorbach and Goldin.

1. LGG® Safety:

• LGG® belongs to the normal microbiota of the gastrointestinal tract and is a natural part of the intestinal barrier;
• LGG® is the most studied strain of probiotic microorganisms;
• LGG® has been in use since 1990;
• LGG® has been described in more than 1000 scientific publications;
• More than 300 clinical studies have been conducted with LGG® in all age groups (from newborns to adults, including pregnant women) on all continents (Asia, Australia, Africa, Europe, North and South America);
• LGG® has been awarded GRAS status “Generally Recognized as Safe” by the FDA (US Food and Drug Administration (2007);
• LGG® has been awarded QPS status “Qualified Presumption of Safety” by the European Food Safety Authority (EFSA).

2. LGG® properties:

• resistance to the effects of hydrochloric acid of gastric juice and bile, therefore, when passing through the gastrointestinal tract, LGG® remains viable;
• maximum adhesive ability - LGG® effectively attach to the epithelium of the intestinal mucosa, colonize it and displace pathogenic flora.

3. LGG® contributes to:

• synthesis of compounds that inhibit the growth of pathogenic microorganisms;
• synthesis of lactic acid, beneficially affecting the development of bifidobacteria;
• reducing the risk of developing microflora imbalance;
• increasing nonspecific resistance of the body;
• increasing the activity of phagocytes;
• increasing the level of immunoglobulins (IgA), anti-inflammatory cytokines, 1L-6,1L-10 (interleukins 6 and 10).

4. Studied effects of LGG® on the human body:

Normolakt, instructions for use (Method and dosage)

Normolakt syrup is taken orally. The dosage of the drug is selected individually. Treatment begins with a higher dose, which is reduced 2-3 times after achieving the effect. When treating hepatic encephalopathy, the dose is from 30 to 50 ml two to three times a day.

For constipation , in the first days of treatment, take 15-45 ml of the drug, and then reduce the dose to 10 to 25 ml. If there is no effect after 2-3 days of use, the initial dose should be increased. It is recommended to take the daily dose of the drug during breakfast in one dose. Normolact can be mixed with food mixtures, vegetable and fruit juices.

Normolact for children under one year of age is measured using a scale on the dosing device provided with the drug. For older children and adults, the drug can be dosed with spoons (teaspoon - 5 ml), (dessert spoon - 10 ml or table spoon - 5 ml. The effect of the drug occurs in 1-2 days.

Indications for use of the drug Normolakt

• constipation (including chronic);
• intestinal dysbiosis;
• intoxication of various origins;
• hypercholesterolemia;
• hepatic encephalopathy;
• liver failure;
• hepatic precoma and coma;
• liver cirrhosis with a tendency to hyperammonemia.

It is also prescribed for putrefactive dyspepsia syndrome in young children, pain syndrome after removal of hemorrhoids; for softening stool in case of hemorrhoids, if surgical intervention on the colon/anus is necessary.

Normolakt's analogs

Level 4 ATC code matches:
Romphalac

Transipeg

Medulak

Fortrans

Exportal

Fleet Phospho-Soda

Good luck

Lactulose

Sorbitol

Duphalac

Normaze

Forlax

Lactulose , Bioflorax , Dufulak , Medulak , Lactuvit , Depurax , Portalak , Normaze and others.

Reviews about Normolakt

Reviews about the drug are overwhelmingly favorable. Patients note its high effectiveness.

• “... Due to a sedentary lifestyle, my grandmother began to experience regular constipation, and it is very difficult to persuade her to take a pill. The use of Normolakt practically solved this problem. Add it to compote or juice.”
• “... Our six-month-old son began to have constipation, we gave enemas, it helped for a while, and then it started again. The doctor recommended Normolact syrup, a day later stool appeared and then everything returned to normal.”

Side effects

In most cases, Normolact is well tolerated by the body and does not cause side effects. A negative reaction of the body can occur in the presence of hypersensitivity to the substances included in the drug or as a result of taking it while ignoring contraindications.

If side effects appear, the use of the drug is discontinued. To adjust the further course of treatment, you should consult your doctor.

Possible side effects:

• diarrhea (may be accompanied by painful sensations in the abdomen);
• headache or dizziness;
• general weakness of the body and drowsiness;
• flatulence (bloating);
• arrhythmia and myalgia (in rare cases);
• attacks of nausea (vomiting in rare cases);
• excessive fatigue of the body.

Overdose

The drug is usually well tolerated, however, in extremely rare cases, diarrhea may occur. If the recommended dosage of syrup is regularly exceeded, diarrhea may occur in combination with pain in the abdominal area. The intensity of pain and the frequency of attacks depend on the individual characteristics of the body.

Taking the drug for too long can cause disturbances in water and electrolyte metabolism. If such symptoms occur, it is necessary to reduce the dosage of Normolact or stop taking it. Treatment of signs of overdose is carried out symptomatically and under the supervision of a specialist.

Contraindications

The presence of gastrocardial syndrome in a patient is the basis for a gradual increase in Normolact dosages. For diabetes mellitus, the drug should be taken only on the basis of doctor’s testimony. For very weak and elderly people, dosages are calculated individually. Self-administration of syrup in the presence of such factors is prohibited. Some conditions are grounds for excluding Normolact from the course of therapy.

It is prohibited to take the drug if you have the following conditions:

• individual intolerance to individual components of the medication;
• increased sensitivity to lactose;
• presence of intestinal obstruction;
• galactosemia.

During pregnancy

Taking Normolact is permitted during pregnancy and lactation. The components included in the drug do not have a negative effect on the fetus and its development. The syrup is also harmless for infants (if ingested through breast milk). This factor does not exclude the need for a pregnant or lactating woman to first consult with a doctor before starting a course of treatment with the drug.

Video on the topic: Constipation during pregnancy. How to help yourself

Normolakt price, where to buy

The price of Normolakt syrup in a 100 ml bottle varies from 126 to 177 rubles per package; in a 200 ml bottle - from 228 to 344 rubles. You can purchase the drug without problems in most pharmacies in Moscow.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine

LuxPharma* special offer

• Normolact syrup bottle 200ml
  1490 rub. order

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