Pharmacological properties of the drug Zincteral
zinc is a trace element that is part of enzymes involved in various biochemical reactions and processes of hormone synthesis in the human body (zinc-dependent hormones are insulin, corticotropin, somatropin, gonadotropin); plays an important role in protein synthesis, carbohydrate metabolism, affects the growth and development of body cells, the functioning of the nervous system, the functioning of the immune system, maintaining normal levels of vitamin A in the blood, necessary for the normal course of pregnancy. The total amount of zinc in the adult human body is 1.4–2.3 g (21.4–35.1 mmol), of which 98% is intracellular zinc. The daily requirement for elemental zinc in adults and children aged 10–15 years is about 15 mg Zn2+; in young children - 5–10 mg Zn2+; during pregnancy and lactation - 15–19 mg Zn2+. Zinc sulfate, which is part of the drug, does not irritate the mucous membrane of the esophagus and stomach, since the protective shell of the Zincteral tablet ensures the release of the drug directly in the duodenum. Absorption of zinc occurs in the duodenum and small intestine. Its bioavailability is 20–30% of the dose taken. The maximum concentration of zinc in the blood plasma is observed 2 hours after administration. Its highest concentration is determined in red blood cells and leukocytes (75%), skin (20%), in small quantities - muscles, bones, kidneys, liver, pancreas, retina, prostate gland, sperm, hair. Zinc is excreted from the body mainly through feces (90%), in small quantities through urine and sweat.
Indications
The doctor prescribes “Zincit” in cases where the patient has a noticeable lack of zinc. Indications may vary:
- intestinal diseases in which zinc absorption is impaired;
- poor nutrition;
- prolonged fasting;
- strict diet;
- acne;
- skin diseases caused by zinc deficiency;
- dysplasia of joints, bones or connective tissue;
- active sports activities;
- smoking and alcoholism, in which zinc is intensively removed from the body.
Zinc is found in sunflower and pumpkin seeds, sesame seeds, almonds, pine nuts, oatmeal, raspberries, black currants, potatoes, oranges, bananas, legumes, cheese and chocolate.
Indications for use of the drug Zincteral
Acrodermatitis enteropathica, baldness and malignant alopecia; pustular and phlegmonous acne, prurigo, brittleness and flowering of nails; when discontinuing long-term corticosteroids; in complex therapy for long-term non-healing wounds (including ulcerative processes of the gastrointestinal tract); if necessary, improve the state of immunity in the treatment and prevention of viral, fungal and protozoal infections, allergic conditions; prevention of benign and malignant processes of the prostate gland; to enhance potency and libido, treatment of male infertility; prevention of blindness in old age; Wilson's disease; migraine.
Important to remember
Zincite is a dietary supplement, not a medicine. A visit to your doctor will allow you to anticipate possible allergic reactions and other complications that may arise from taking the drug. It is often drunk by athletes during long training sessions with heavy loads, as well as by people on a strict diet to lose weight. This remedy not only treats zinc deficiency, but also serves to prevent this condition.
Well-known analogues of “Zinkit” are “Zinketral”, “Tsinketral-teva”, “Roaccutane”, “Zinkorol”, “Sotret”, “Solgar zinc picolinate”.
All vitamins and minerals are beneficial to the body. Health deteriorates both with their deficiency and with their excess. Additional nutritional supplements will compensate for the lack of essential substances caused by poor nutrition or due to impaired absorption of zinc. You should take the pills only after visiting your doctor.
Use of the drug Zincteral
Orally before meals for adults and children - usually 0.4–1.2 g/day in 3 divided doses. For enteropathic acrodermatitis, alopecia areata and malignant alopecia in adults and children over 4 years of age - up to 4 tablets per day, when clinical improvement is achieved, the dose is reduced to 3 tablets per day, and then - 1-2 tablets per day. To improve wound healing - 1-2 tablets per day, treatment of erosions and ulcers of the digestive tract - 1-2 tablets 3 times a day. For pustular and phlegmonous acne, discontinuation of long-term corticosteroid therapy - 1-2 tablets 3 times a day. To increase immunity in the treatment and prevention of viral, fungal and protozoal infections - 2-3 tablets 2 times a day. To prevent the development of blindness in the elderly - 1-2 tablets 2 times a day. To enhance potency and libido, treat male infertility, prevent the development of benign and malignant processes in the prostate gland - 2-10 tablets per day, depending on the age and condition of the patient. For Wilson's disease - 1-2 tablets 3 times a day.
Zincteral 124 mg tbl p/p about N25
Zincteral-Teva - instructions for use
Trade name of the drug: Zincteral-Teva
INN or group name: zinc sulfate
Dosage form: film-coated tablets
Compound
Active substance: zinc sulfate heptahydrate (in terms of zinc sulfate monohydrate) - 124 mg Excipients: potato starch, povidone, talc, magnesium stearate, lactose monohydrate.
Shell: hypromellose (hydroxypropyl methylcellulose), macrogol (polyoxyethylene glycol), titanium dioxide, azorubic varnish E122. * 124 mg of zinc sulfate monohydrate corresponds to 45 mg of zinc ion. Description Round, biconvex, pink-violet film-coated tablets.
Pharmacological group: zinc preparation
ATX code: A12SV01
Pharmacological properties Zinc is one of the most important microelements.
It is part of almost |
200 enzymes that determine the course of various metabolic processes, including protein synthesis and carbohydrate metabolism. Zinc stimulates the synthesis of collagen and protein in regenerating tissue, has a drying and astringent effect; stimulates insulin synthesis. Activates carbonic anhydrases and superoxide dismutases of erythrocytes, cytosolic superoxide dismutases, glutamate dehydrogenases; alkaline phosphatase hydrolase, aminopeptidase, neutral protease. Indications for use Prevention and treatment of zinc deficiency caused by inadequate and unbalanced nutrition, malabsorption and other conditions that impair the absorption of zinc and increase its loss by the body.
Acrodermatitis enteropathica (enteropathic acrodermatitis), acne pustulosa and acne phlegmonosa (purulent and phlegmonous acne).
With long-term treatment with corticosteroids, especially at the time of drug withdrawal. As an auxiliary treatment of difficult-to-heal wounds. Contraindications Hypersensitivity to the components of the drug, children under 4 years of age.
Directions for use and dosage: Inside.
The tablets should not be split or chewed.
Zincteral-Teva should be taken on the recommendation of a doctor. Enteropathic acrodermatitis Adults: 1 tablet 3 times a day 1 hour before or 2 hours after meals. Children over 4 years old: 1 tablet per day. Upon achieving clinical improvement, the dose is reduced to 1 tablet 2 times a day, and then 1 tablet per day until the symptoms of the disease completely disappear. Purulent and phlegmonous acne Adults: 1-2 tablets per day; Children over 4 years old: 1 tablet per day. For zinc deficiency: Adults: 1-2 tablets per day. Children over 4 years old: 1 tablet per day. The drug is used 1 hour before or 2 hours after meals, since many foods can interfere with the absorption of zinc. If symptoms of gastrointestinal irritation occur, the drug can be used immediately before or during meals, which, in turn, may reduce absorption and weaken the effect of the drug. Side effects Allergic reactions.
Copper deficiency.
Gastrointestinal disorders (nausea, diarrhea, heartburn), hematological disorders caused by zinc-induced copper deficiency, including leukopenia, accompanied by fever, chills, sore throat, neutropenia, accompanied by the formation of ulcers in the oral cavity and pharynx, sideroblastic anemia, accompanied by a feeling of fatigue and weakness. A headache and a metallic taste in the mouth may occur. If the above symptoms occur, stop using the drug and consult a doctor immediately. Overdose Symptoms of overdose: burning pain in the mouth and throat, watery or bloody diarrhea, belching, vomiting, decreased blood pressure, pulmonary edema, jaundice.
The following may also be observed: hematuria, anuria, collapse, convulsions, hemolysis.
Treatment: Take plenty of milk or water, contact your doctor or seek medical help if necessary. It may be necessary to use intramuscularly or intravenously calcium - disodium salt of ethylenediaminetetraacetic acid (Edetic acid) at a dose of 50-75 mg/kg body weight per day in 3-6 fractional doses for no more than 5 days. Interaction with other drugs Zinc salts reduce the absorption of tetracyclines and copper (the drug should be used no earlier than 2 hours after taking these drugs).
Thiazide diuretics increase the excretion of zinc in the urine.
Folic acid may interfere with the absorption of zinc to a small extent. High doses of iron, penicillamine and other complexing agents significantly reduce the absorption of zinc (should be used no earlier than 2 hours after taking these drugs). Combination medications (eg, multivitamin and mineral supplements containing zinc)—Concomitant use of multiple medications containing zinc may result in high plasma zinc concentrations. A diet rich in phosphates (eg dairy products), grain baked goods or vegetables - limit the absorption of zinc by binding into non-absorbable complexes; This kind of food can be taken at least 2 hours after using zinc salts. Special instructions If you miss a dose of Zincteral-Teva, you should take the next dose at the usual time.
Do not take a double dose to make up for a missed dose.
With long-term use of zinc preparations, the risk of copper deficiency should be taken into account. The drug does not affect the ability to drive vehicles. During treatment you should avoid drinking alcohol. Release form Film-coated tablets 124 mg.
25 tablets per blister (A1/RUS).
1 blister is placed in a cardboard box along with instructions for use. 150 tablets per polymer jar. Each jar is placed in a cardboard box along with instructions for use. Storage conditions Store in a dry place at a temperature of 15 to 25 C.
Keep out of the reach of children.
Shelf life: 3 years.
Do not use after the expiration date stated on the package.
Conditions for dispensing from pharmacies Without a prescription.
Manufacturer Teva Kutno S.A., Poland 25, st.
Sienkiewicz, 99-300 Kutno, Poland
Legal entity in whose name the RU was issued: Teva Pharmaceutical Enterprises Ltd.,
Israel.
Send consumer complaints to the address: 119049, Moscow, st.
Shabolovka, 10, building 1. September 9, 2021
The appearance of the product may differ from the photographs on the website.
Information about medications posted on the site is intended for specialists and includes materials from publications from different years. The information provided on the site is general and is presented for informational purposes only, does not replace consultation with a doctor and cannot serve as a guarantee of the positive effect of the drug. Tvoyaapteka.rf warns you about possible negative consequences that may arise as a result of incorrect use of the information presented on the site and strongly recommends that you consult with a specialist before choosing a drug.
You can find detailed and up-to-date instructions for the drug on the website of the State Register of Medicines www.grls.rosminzdrav.ru.
Special instructions for the use of the drug Zincteral
If dyspeptic disorders occur during the use of the drug, its use should be combined with food intake. Dairy products, baked goods, foods rich in fibrin (for example, bran) inhibit the absorption of zinc salts in the digestive tract (the time between the consumption of these products and the use of zinc preparations should be at least 2 hours). During treatment with Zincteral you should avoid drinking alcohol. With long-term use of Zincteral, copper preparations should be taken (with the exception of Wilson's disease). The drug does not affect the ability to drive vehicles or operate moving machinery. The effect of Zincteral during pregnancy and lactation has not been studied.
Contraindications
If there are cases when it is impossible to take Zincit, then the doctor prescribes another drug. Zinkit has very few contraindications:
- severe diseases and kidney damage;
- allergy to the components of the product, high sensitivity to them;
- acute renal failure;
- immune encephalitis;
- autoimmune diseases and active processes.
A doctor's consultation is required. The doctor must examine the patient and either allow him to take this medicine or prescribe another remedy.
Interactions of the drug Zincteral
If you are taking Zincteral and other medications at the same time, you must inform your doctor about this. Zincteral reduces the absorption of tetracycline drugs and those containing copper in the digestive tract, so it should be used no earlier than 2 hours after taking these drugs. Iron supplements and penicillamine impair the absorption of zinc (the interval between the use of these drugs and Zincteral should be at least 2 hours), folic acid also slightly impairs the absorption of zinc. Thiazide diuretics increase the excretion of zinc in the urine. When taking Zincteral in combination with multivitamin preparations with minerals that contain zinc, signs of overdose may occur.
Overdose
Excessive consumption of Zincite causes the same symptoms of overdose that occur with excess zinc in the body:
- rapid pulse;
- vomiting, diarrhea, nausea;
- dizziness;
- pain in the head and lower back;
- ulcers in the mouth and throat;
- fever and other flu-like symptoms;
- the level of “good” cholesterol drops sharply;
- taste sensations change or disappear completely;
- immunity decreases;
- the amount of copper in the body also decreases sharply.
Zinc overdose is very dangerous. It is necessary to consult a doctor so that he can relieve the symptoms and prescribe a different, more strict dose. You will need to be hospitalized in the toxicology department of the hospital. As a diet, the patient is prescribed milk and given activated charcoal. All doctor's recommendations must be followed.
