Beneficial bacteria constantly live inside the vagina, which form the internal environment and provide local immunity. Under the influence of infectious processes, hormonal imbalances, as well as after childbirth or operations, the use of antibiotics, the microflora is disrupted. Balance can be restored in a few days or weeks. One of the effective remedies is Acylact suppositories.
Composition and description of the drug "Acilact"
"Acylact" is a drug that is available in the form of powder, lyophilisate, tablets and vaginal suppositories. The composition includes live bacteria - lactobacilli acidophilus and additional (auxiliary) components.
The product has a probiotic effect. It normalizes the vital activity of bacterial colonies that constantly live in the female genitalia, ensures normal metabolism of glycogen with the formation of the final product - lactic acid.
The drug also allows you to normalize the acidity level (pH) of the internal environment of the genital organs. The action of lactobacilli leads to a decrease in pH - the environment becomes acidic, which leads to the death of pathogenic bacteria. Thanks to this, local immunity increases, the body better resists infections.
Important!
Candles should be stored in the refrigerator at a temperature range of 2-10 degrees. Access for children is prohibited. The shelf life is 1 year - the drug cannot be used after this time.
Femilex 100 mg supp vag No. 10
Dosage
100 mg
Active substance
Lactic acid
Manufacturer
NIZHFARM JSC (Russia)
Shelf life
5 years
Storage conditions
At a temperature not exceeding 25 °C
Registration certificate number
LP-001689 dated 01/14/2019
Compound
| Vaginal suppositories | 1 sup. |
| active substance: | |
| lactic acid | 100 mg |
| excipients: macrogol mixture: macrogol 1500 - 92–98%; macrogol 400 — 8–2% |
Characteristic
| Vaginal suppositories | 1 sup. |
| active substance: | |
| lactic acid | 100 mg |
| excipients: macrogol mixture: macrogol 1500 - 92–98%; macrogol 400 — 8–2% |
Description of the dosage form
Suppositories are white or white with a yellowish tint, torpedo-shaped. Marbling and the presence of an air core and a funnel-shaped depression on the cut are allowed.
Pharmacokinetics
There is no information on pharmacokinetics.
Pharmacodynamics
Lactic acid is a natural waste product of lactic acid bacteria in the vagina and provides a pH of vaginal secretions in the range of 3.5–4.5. Suppositories with lactic acid help restore and maintain normal pH and vaginal flora, suppress the growth of acid-sensitive pathogenic and conditionally pathogenic flora.
Lactic acid creates an acid reserve to correct the pH shift to the alkaline side observed during vaginal infections. Helps enhance the vagina's natural protection against genital infections.
Contraindications
hypersensitivity to the components of the drug;
vulvovaginal candidiasis;
children's age (up to 18 years).
Use during pregnancy and breastfeeding
No special studies of the drug Femilex® have been conducted during pregnancy and breastfeeding. In animal studies, there was no evidence of toxic effects of lactic acid on the fetus. In clinical studies of lactic acid in various dosage forms for intravaginal administration, no safety problems were identified. Considering the fact that lactic acid is an intermediate product of mammalian metabolism and is normally found in the human body, incl. in amniotic fluid, breast milk, the use of Femilex® during pregnancy and breastfeeding is possible after assessing the potential benefit to the mother and the risk to the fetus and breastfed infant.
Before use, you should consult your doctor.
Directions for use and doses
Intravaginally.
Before use, the suppository is released from the contour packaging.
1 vaginal suppository is inserted into the vagina (lying on your back with slightly bent legs) 1 time per day.
The course of treatment is 10 days.
If there is no improvement after treatment or new symptoms appear, you should consult your doctor.
The drug should be used only according to the indications, the method of administration and in the doses indicated in the description.
Side effects
Possible allergic reactions, itching, and in isolated cases, burning in the vagina, which disappear after discontinuation of the drug.
If any of the side effects listed in the description get worse or other side effects not listed in the description are noted, you should immediately consult a doctor.
Interaction
No information available.
Overdose
No cases of drug overdose have been reported.
special instructions
If burning and itching occurs, it is recommended to conduct an examination to exclude a fungal infection of the vagina.
Impact on the ability to drive vehicles and machinery.
Does not affect.
Conditions for dispensing from pharmacies
Over the counter.
Pharmgroups
Antiacidotic agent (Antiseptics and disinfectants)
"Acilact" suppositories: indications for use
Vaginal suppositories are used as a primary or additional means of therapy to treat a number of pathologies:
- gynecological diseases that are accompanied by disturbances in the microflora of the female genitalia;
- vaginal dysbiosis;
- nonspecific colpitis;
- inflammatory pathologies of the genital organs in subacute and chronic forms;
- colpitis is atrophic and hormone-dependent.
The product is also used to prevent dysbacteriosis and complications of infectious processes during operations or childbirth.
Contraindications and side effects
There are not many contraindications for use. The product should not be used if you have diagnosed vaginal candidiasis. In these cases, a separate course of treatment is first carried out, after which the doctor may prescribe Acylact suppositories to restore normal vaginal microflora.
Also, the drug is not used in the presence of individual intolerance to the active or auxiliary components. If allergic reactions occur, treatment is stopped. It is recommended to consult a doctor - you may need to change therapy.
No side effects have been reported to date. Suppositories are safe when used in certain dosages specified in the instructions. No cases of overdose have been identified either.
Vaginal microflora
Vaginal microflora smear
The study of vaginal microflora consists of three stages:
- Exclusion of sexually transmitted infections.
- Microscopic examination of a Gram-stained smear.
- Sowing on flora.
The main indicative test for vaginal microflora is a smear.
Under the magnification of a microscope, the doctor can immediately see some microorganisms.
These are the causative agents of sexually transmitted infections: Trichomonas and gonococci.
And also candida - opportunistic fungi.
Their detection in a smear indicates an excessive increase in the population.
This condition is called candidiasis or thrush.
Also, microscopy evaluates:
- state of the epithelium;
- number of white blood cells (inflammatory cells);
- the presence and completeness of phagocytosis reactions (absorption and dissolution of bacteria by leukocytes);
- the presence of individual representatives of microflora (cocci, rods, leptothrix, etc.).
Contamination of the vagina with microbes is assessed in points.
In the analysis results you will see from one to four advantages:
- 1 – less than 10 microbial cells in the field of view.
- 2 – up to 100 cells.
- 3 – up to 1000 cells.
- 4 – more than 1000 cells.
Sowing of vaginal microflora
Another informative research method is microflora culture.
Currently, it has become possible to determine not only the species of certain microorganisms, but also their quantity in the material under study.
Culture allows you to assess the ratio of lactobacilli and opportunistic flora.
Normally, there should be more lactobacilli.
If there are fewer of them than other bacteria, then the vaginal microbiocenosis is considered disturbed.
This condition requires treatment.
Pathogenic microflora of the vagina
Sometimes microscopic examination reveals pathogenic microflora of the vagina.
It could be gonococci or trichomonas.
In addition, in women at risk, it is necessary to exclude STIs in all cases where symptoms of vaginitis are observed.
For this purpose, PCR is used for the most common sexually transmitted diseases.
The clinical material that is used is a urethral swab.
Chlamydia, Trichomonas, gonococci and other STI pathogens may be detected in the test material.
How to restore vaginal microflora?
Restoration of the vaginal microflora occurs in 2 stages.
- 1 – destruction of “bad” microbes.
- 2 – restoration of “good” microbes.
The drugs used in the first stage of treatment may be different.
The choice depends on the results of research - microscopy and flora culture.
Antimicrobial agents are prescribed based on which microorganisms predominate in the vaginal microbiocenosis.
Clindamycin, metronidazole, chlorhexidine can be used.
Lactic acid is used to increase vaginal pH.
If there are problems with the immune system, immunomodulators are used.
In case of estrogen deficiency (for example, in postmenopause), hormonal replacement therapy is indicated.
In some situations, prostaglandins and antihistamines may be used.
For severe itching or pain, suppositories with local anesthetics (benzocaine) are prescribed.
Suppositories for vaginal microflora
At the second stage of normalizing the vaginal microflora, suppositories with lactobacilli (eubiotics) are used.
They allow you to “populate” a woman’s reproductive tract with “useful” microbes.
In the future, this reduces the risk of relapse of bacterial vaginosis or nonspecific vaginitis.
Names of drugs: Acipol, Acylact, Lactobacterin.
As a rule, treatment with eubiotics begins 3 days after the end of antibacterial therapy.
During this time, they are usually eliminated from the body.
Therefore, a situation will not arise when lactobacilli “settled” in the vagina are immediately destroyed by antibiotics.
If you experience symptoms of vaginitis or bacterial vaginosis, contact our clinic.
With us you can quickly get all the necessary tests and receive adequate treatment.
Instructions for use of "Acilact" suppositories
Suppositories are used intravaginally, i.e. inserted directly into the vagina. The instructions are:
- Rinse the genitals thoroughly.
- Wash your hands with soap and dry.
- Remove the packaging from the suppository (only before administration).
- Lie on your back and insert the suppository as deeply as possible.
Take 1 or 2 suppositories per day, and the duration is 10 days. Then a break is taken for 10 or 20 days, after which the cycle is repeated if necessary. It is recommended to discuss the dosage and duration of therapy with your doctor.
Instructions for medical use of the drug Femilex®
Trade name of the drug:
Femilex®
International nonproprietary or chemical name:
lactic acid
Dosage form:
vaginal suppositories
Compound:
One suppository contains: active ingredient: lactic acid – 100 mg; excipients: macrogol mixture: macrogol 1500 – (92–98)%, macrogol 400 – (8–2)%.
Description:
Suppositories are torpedo-shaped, white or white with a yellowish tint. Marbling and the presence of an air core and a funnel-shaped depression on the cut are allowed.
Pharmacotherapeutic group:
antiseptic
ATX code:
G01AD01
pharmachologic effect
Pharmacodynamics
Lactic acid is a natural waste product of lactic acid bacteria in the vagina and provides a pH of vaginal secretions in the range of 3.5-4.5. Suppositories with lactic acid help restore and maintain normal pH and vaginal flora, suppress the growth of acid-sensitive pathogenic and conditionally pathogenic flora. Lactic acid creates an acid reserve to correct the pH shift to the alkaline side observed during vaginal infections. Helps enhance the vagina's natural protection against genital infections.
Pharmacokinetics
There is no information on pharmacokinetics.
Indications for use
Normalization of disturbed microflora and vaginal pH, including bacterial vaginosis (as part of complex therapy).
Contraindications
Hypersensitivity to the components of the drug, vulvovaginal candidiasis, children (up to 18 years).
Use during pregnancy and breastfeeding
No special studies of the drug Femilex® have been conducted during pregnancy and breastfeeding. In animal studies, there was no evidence of toxic effects of lactic acid on the fetus. In clinical studies of lactic acid in various dosage forms for intravaginal administration, no safety problems were identified. Considering the fact that lactic acid is an intermediate product of mammalian metabolism and is normally found in the human body, including in amniotic fluid and breast milk, the use of Femilex® during pregnancy and breastfeeding is possible after assessing the potential benefits for the mother and risk to the fetus and breastfed infant. Before use, you should consult your doctor.
Directions for use and doses
Intravaginally. Before use, the suppository is released from the contour packaging. One vaginal suppository is inserted into the vagina (lying on your back with slightly bent legs) once a day. The course of treatment is 10 days. If there is no improvement after treatment or new symptoms appear, you should consult your doctor. Use the drug only according to the indications, method of administration and in the doses indicated in the instructions.
Side effect
Allergic reactions, itching, and in isolated cases, burning in the vagina, which disappear after discontinuation of the drug, are possible. If any of the side effects indicated in the instructions worsen or other side effects not listed in the instructions are noted, you should immediately consult a doctor.
Overdose
No cases of drug overdose have been reported.
Interaction with other drugs
No information available.
special instructions
If burning and itching occurs, it is recommended to conduct an examination to exclude a fungal infection of the vagina.
Impact on the ability to drive vehicles and machinery
Does not affect.
Release form
Vaginal suppositories 100 mg. 5 suppositories in a blister pack made of polyvinyl chloride film laminated with polyethylene. 1 or 2 blisters along with instructions for medical use of the medicinal product in a cardboard pack.
Storage conditions
At a temperature not higher than 25°C. Keep out of the reach of children.
Best before date
5 years. Do not use after expiration date.
Vacation conditions
Available without a prescription.
Manufacturer/organization accepting claims:
JSC "NIZHFARM", Russia 603950, Nizhny Novgorod, st. Salganskaya, 7 Tel. Fax E-mail:
