Hexicon 05% 20g gel for local and external use

How to use the solution

The solution can be used externally and locally in the form of rinses and irrigations. Apply about 5-10 ml to the affected area. Repeat 2 times a day.

In order to prevent sexually transmitted infections, you should use the solution no later than 2 hours from the moment of unprotected intercourse.

A special nozzle in the package allows you to inject the solution into the urethra (up to 3 ml) or into the vagina (up to 10 ml). You need to hold the nozzle for a couple of minutes. The solution must be wiped over the inside of the thigh and genitals.

Hexicon for men

Some inflammatory diseases in men are also treated with Hexicon. Scheme of use of different forms of release of the drug:

1. Gel. When treating urological diseases, it is applied to the lesions twice a day for 7-10 days.
2. Solution. In order to prevent sexually transmitted infections, liquid is injected into the urethra in an amount of 2-3 ml. The nozzle should be held for 2-3 minutes. For inflammation of the urethra, including complicated by prostatitis, the solution is injected into the urethra for 10 days 1-2 times a day. The procedure is carried out with a break of 1 day.

Where to put Hexicon candles

The suppository is inserted into the vagina as deeply as possible. To prevent the contents from leaking out, it is better to take a lying position and spread your legs at the knees. If the candle is not inserted deeply enough, then when the girl gets up, it may fall out without completely dissolving.

Suppositories work in exactly the same way as vaginal baths. Hexicon must be administered several times a day, as a result of which the amount of discharge increases. That is why during therapy it is worth wearing a new panty liner as often as possible.

Hexicon 16 mg 10 pcs. vaginal tablets nizhpharm

pharmachologic effect

Chlorhexidine is an antiseptic drug for local intravaginal use, active against protozoa, gram-positive and gram-negative bacteria, viruses, including Treponema pallidum, Chlamydia spp., Ureaplasma spp., Neisseria gonorrhoeae, Trichomonas vaginalis, Gardnerella vaginalis, Bacteroides fragilis, Herpes simplex 2 type. Some strains of Pseudomonas spp., Proteus spp. are weakly sensitive to the drug, and acid-resistant forms of bacteria, bacterial spores, and fungi are also resistant. Chlorhexidine does not interfere with the functional activity of lactobacilli. Remains active (albeit somewhat reduced) in the presence of blood and pus.

Composition and release form Hexicon 16 mg 10 pcs. vaginal tablets nizhpharm

One tablet contains:

active ingredient - chlorhexidine bigluconate - 16.0 mg (in the form of chlorhexidine bigluconate solution 20% - 85.2 mg);

excipients: microcrystalline cellulose, pregelatinized corn starch, povidone K 17, stearic acid, lactose monohydrate. Vaginal tablets 16 mg. 5 or 10 tablets in a blister pack made of polyvinyl chloride film and printed varnished aluminum foil. 1, 2 blister packs of 5 tablets each or 1 blister pack of 10 tablets, together with instructions for use of the medicinal product, are placed in a cardboard pack.

Description of the dosage form

Vaginal tablets

Characteristic

Tablets are white or white with a yellowish tint, biconvex, oblong. Slight marbling of the surface is allowed.

Directions for use and doses

Intravaginally. Before use, it is recommended to moisten the tablet in water.

For treatment: 1 vaginal tablet 1-2 times a day for 7-10 days.

To prevent sexually transmitted infections: 1 vaginal tablet no later than 2 hours after unprotected intercourse.

If symptoms persist for more than 7 days, it is recommended to consult a doctor.

Use the drug only according to the method of use and in the doses indicated in the instructions for use. If necessary, please consult your doctor before using the medicine.

Pharmacodynamics

A local antiseptic with a predominantly bactericidal effect against gram-positive and gram-negative bacteria, and has a fungicidal and virucidal effect (against lipophilic viruses). Active against protozoa, gram-positive and gram-negative bacteria, viruses, including Treponema pallidum, Chlamydia spp., Ureaplasma spp., Neisseria gonorrhoeae, Trichomonas vaginalis, Gardnerella vaginalis, Bacteroides fragilis, Herpes simplex type 2. Some strains of Pseudomonas spp., Proteus spp. are weakly sensitive to the drug, and acid-resistant forms of bacteria and bacterial spores are also resistant. Chlorhexidine does not interfere with the functional activity of lactobacilli. Remains active (albeit somewhat reduced) in the presence of blood and pus.

Pharmacokinetics

Systemic absorption after intravaginal use is negligible.

Indications for use Hexicon 16 mg 10 pcs. vaginal tablets nizhpharm

Treatment of bacterial vaginosis, colpitis (including nonspecific, mixed, trichomonas).

Prevention of infectious and inflammatory complications in obstetrics and gynecology (before surgical treatment of gynecological diseases, before childbirth and abortion, before and after installation of an intrauterine device (IUD), before and after diathermocoagulation of the cervix, before intrauterine examinations).

Prevention of sexually transmitted infections (chlamydia, ureaplasmosis, trichomoniasis, gonorrhea, syphilis, genital herpes) - use no later than 2 hours after sexual intercourse.

Contraindications

Hypersensitivity to chlorhexidine and other components of the drug, children under 18 years of age.

Application Hexicon 16 mg 10 pcs. Nizhpharm vaginal tablets during pregnancy and breastfeeding

The use of the drug during pregnancy and breastfeeding is possible only after a careful assessment of the expected benefit to the mother and the risk to the fetus and child.

special instructions

In childhood, it is recommended to use the drug Hexicon® D.

Overdose

Cases of overdose are unknown. When using the drug in accordance with the instructions for use, an overdose is unlikely.

Side effects Hexicon 16 mg 10 pcs. vaginal tablets nizhpharm

Allergic reactions and vaginal itching are possible, which disappear after discontinuation of the drug.

Severe allergic reactions, including anaphylaxis.

If any of the side effects indicated in the instructions get worse or you notice any other side effects not listed in the instructions, tell your doctor.

Drug interactions

Concomitant use with iodine-containing drugs used intravaginally is not recommended.

Chlorhexidine is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps if they are administered intravaginally.

Compatible with drugs containing a cationic group (benzalkonium chloride, cetrimonium bromide).

Can Hexicon be used by pregnant women?

The drug Hexicon in any form (except vaginal tablets) can be given during pregnancy. The drug does not pose any threat to the fetus and the expectant mother.

During pregnancy, if there are gynecological problems, women are more often prescribed suppositories. The harmlessness of the drug is explained by its local action. This is evidenced by many years of experience. The active components do not enter the blood, which does not pose a threat to the developing fetus. Candles can be used at any month of pregnancy.

special instructions

Hygiene procedures do not affect the effectiveness of therapy with suppositories or vaginal tablets. It is important to avoid getting the solution into the wound in patients with brain or spinal cord injuries or perforation of the eardrum. In case of accidental contact with the mucous membrane of the eye, immediate rinsing is required. During treatment, it is recommended to avoid sexual intercourse. Regular sex life reduces the effectiveness of therapy. The result may be re-infection, which will require the use of not only local drugs, but also systemic ones.

Is it possible to use Hexicon while breastfeeding?

The medication in any form (with the exception of vaginal tablets) can be given during lactation.

The active ingredients do not enter the blood or milk, so they do not pose any threat to the baby.

A specialist may prescribe vaginal tablets during pregnancy and breastfeeding in rare cases, if the expected benefit is several times greater than the possible risk.

Under no circumstances should you self-medicate while pregnant. Before taking it, be sure to consult a specialist.

During pregnancy

Each dosage form of the antiseptic is approved for use during pregnancy and lactation. It is not only effective during this period, but also completely safe for both mother and fetus. The exception is vaginal tablets. They are used only when the expected benefit outweighs the potential harm. In the 1st and 2nd trimester of pregnancy, indications for use are:

• ureaplasmos;
• gonorrhea;
• chlamydia;
• trichomoniasis;
• genital herpes;
• exocervicitis;
• bacterial vaginosis;
• colpitis;
• vaginitis

Although the drug is ineffective against Candida fungi, it is still prescribed for the treatment of thrush in pregnant women. The reason is that more often a fungal infection during this period in women is provoked by gonococci, Trichomonas and other bacteria. With a mixed fungal-bacterial nature of thrush, Hexicon is able to relieve signs of inflammation, reduce swelling and significantly reduce the severity of signs of the disease.

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Side effects

The most common reaction to the use of suppositories is a local allergic reaction in the form of burning and itching in the vagina. When these symptoms appear, there is no need for specific treatment. They go away on their own after completing the course of therapy. Very rarely, adverse reactions occur after using the solution. It could be allergies and itching. Judging by patient reviews, other undesirable reactions may occur:

• dermatitis;
• dry skin of hands;
• sticky hands;
• photosensitivity;
• Tartar deposits;
• staining of tooth enamel;
• taste disturbance.

Drug interactions

If ethanol is used simultaneously, the effectiveness of the drug will increase. It is not recommended to be treated with Hexicon together with products containing iodine. Other features of the interaction of this medication with other drugs:

• since suppositories are administered intravaginally, their tolerability and effectiveness are not affected by the sanitation of the external genitalia;
• incompatible with anionic detergents and soap, in the presence of which chlorhexidine is inactivated;
• approved for use with drugs containing a cationic group.

Analogue of Hexicon

Complete analogues of the medication are Chlorhexidine solution and Amident. If we compare the mechanisms of action, then Depantol, Bepanten, Citeal, Lavasept are closer. The list of analogues can include the following drugs:

• Iodoxide;
• Trichomonacid;
• Dafnedjin;
• Lactozhinal;
• McMiror;
• Betadine;
• Vagiflor;
• Iodovidone;
• Hyposol;
• Furazolidone.

Hexicon price

If you study drug catalogs in several online pharmacies, you will see different prices for Hexicon. This is due to the large number of manufacturers and forms of release of the drug. The table describes approximate prices: