PIOBACTERIOPHAGE COMPLEX solution for oral, local and external use 100ml bottle
Pyobacteriophage is intended for local and oral use, as well as for rectal administration. Treatment of purulent-inflammatory processes is recommended through simultaneous local and oral administration of the drug Piobacteriophage. Depending on the location of the infection, Pyobacteriophage is recommended for: 1. Local application in the form of lotions, irrigations, applications and tampons, moistened solutions. In this case, use the required amount of solution based on the size of the affected area. For abscesses, the solution should be injected into the cavity after removing the pus by puncture (the volume of the solution should be slightly less than the volume of the extracted pus). 2. Injection of the solution into the pleural, articular and other limited cavities. After administering the required amount of bacteriophage, capillary drainage is left, through which repeated doses of the drug are subsequently administered. 3. Injection of the solution into the drained cavity of the bladder and renal pelvis through a cystostomy or nephrostomy. 4. Introducing the solution into the uterine or vaginal cavity, including in the form of tampons soaked in the solution. 5. Instillation, washing and rinsing, as well as the introduction of turundas moistened with a solution, in otolaryngological practice. 6. Applications to the conjunctival sac in ophthalmological practice. 7. Insertion of moistened turundas into periodontal pockets in dental practice. 8. Introductions into the rectum in the form of enemas in gastroenterological practice. The dose of the drug Piobacteriophage and the duration of the course of therapy are determined by the doctor. A single dose recommended for children under 6 months is 5 ml when administered orally or 10 ml when administered rectally. A single dose recommended for children 6-12 months is 10 ml when administered orally and 20 ml when administered rectally. A single dose recommended for children 1-3 years old is 15 ml when administered orally and 30 ml when administered rectally. A single dose recommended for children 3-8 years old is 20 ml when administered orally and 40 ml when administered rectally. A single dose recommended for children over 8 years of age and adults is 30 ml when administered orally and 50 ml when administered rectally. In the treatment of purulent-inflammatory diseases and intestinal diseases, as a rule, the appropriate single dose is prescribed three times a day. If, when using a bacteriophage locally, the wound was pre-treated with an antiseptic, it is necessary to wash the wound with a 0.9% sodium chloride solution before using the Piobacteriophage solution. For children under 6 months of age with enterocolitis and sepsis, Piobacteriophage solution is administered in the form of high enemas twice or thrice a day. If the child does not develop regurgitation and vomiting, the drug can be given orally. The average duration of therapy is from 5 to 15 days. As a prophylaxis, the drug is prescribed in a single dose twice a day for 5-7 days.
Pyobacteriophage Complex solution for internal and local use 100ml
Compound
The solution contains:
Active substances: a mixture of sterile filtrates of phagolysates of staphylococci, streptococci, enterococci, Proteus, Klebsiella (pneumonia and oxytoca), Pseudomonas aeruginosa and Escherichia coli 100 ml.
Pharmacokinetics
Pyobacteriophage liquid complex is a preparation that has a specific selective antibacterial effect. Pyobacteriophage is active against strains of streptococci, Proteus, staphylococci, enterococci, oxytoca, Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli. Pyobacteriophage lyses sensitive bacteria due to the ability to attach to their membrane and penetrate into the cell. In a bacterial cell, phage particles multiply at the expense of the energy resources of microorganisms, which leads to their death. After the death of a bacterial cell, mature phage particles emerge that can infect other sensitive microorganisms. Pyobacteriophage does not affect other types of bacteria and does not cause disturbances in the natural microflora.
Indications for use
Treatment and prevention of purulent-inflammatory and intestinal diseases caused by staphylococci, enterococci, streptococci, Pseudomonas aeruginosa, Klebsiella, pathogenic Escherichia coli of various serogroups, Proteus for internal, rectal and external use:
- Diseases of the ear, throat, nose, respiratory tract and lungs: inflammation of the sinuses, middle ear, sore throat, pharyngitis, laryngitis, tracheitis, bronchitis, pneumonia, pleurisy.
- Surgical infections: wound suppuration, burns, abscess, phlegmon, boils, carbuncles, hydroadenitis, panaritium, paraproctitis, mastitis, bursitis, osteomyelitis.
- Urogenital infections: urethritis, cystitis, pyelonephritis, colpitis, endometritis, salpingoophoritis.
- Post-traumatic conjunctivitis, keratoconjunctivitis, purulent corneal ulcers and iridocyclitis.
- Enteral infections: gastroenterocolitis, cholecystitis, dysbacteriosis.
- Generalized septic diseases.
- Purulent-inflammatory diseases of newborns: omphalitis, pyoderma, conjunctivitis, gastroenterocolitis, sepsis, etc.
- Other diseases caused by bacteria: staphylococci, streptococci, enterococci, Proteus, Klebsiella pneumoniae and oxytoca, Pseudomonas aeruginosa and Escherichia coli.
For prophylactic purposes, the drug is used for the treatment of surgical and newly infected wounds, as well as for the prevention of nosocomial infections for epidemic indications.
An important condition for effective phage therapy is the preliminary determination of the phage sensitivity of the pathogen.
Contraindications
None.
Directions for use and doses
Pyobacteriophage is intended for local and oral use, as well as for rectal administration. Treatment of purulent-inflammatory processes is recommended through simultaneous local and oral administration of the drug Piobacteriophage. Depending on the location of the infection, Pyobacteriophage is recommended for: 1. Local application in the form of lotions, irrigations, applications and tampons, moistened solutions. In this case, use the required amount of solution based on the size of the affected area. For abscesses, the solution should be injected into the cavity after removing the pus by puncture (the volume of the solution should be slightly less than the volume of the extracted pus). 2. Injection of the solution into the pleural, articular and other limited cavities. After administering the required amount of bacteriophage, capillary drainage is left, through which repeated doses of the drug are subsequently administered. 3. Injection of the solution into the drained cavity of the bladder and renal pelvis through a cystostomy or nephrostomy. 4. Introducing the solution into the uterine or vaginal cavity, including in the form of tampons soaked in the solution. 5. Instillation, washing and rinsing, as well as the introduction of turundas moistened with a solution, in otolaryngological practice. 6. Applications to the conjunctival sac in ophthalmological practice. 7. Insertion of moistened turundas into periodontal pockets in dental practice. 8. Introductions into the rectum in the form of enemas in gastroenterological practice. The dose of the drug Piobacteriophage and the duration of the course of therapy are determined by the doctor. A single dose recommended for children under 6 months is 5 ml when administered orally or 10 ml when administered rectally. A single dose recommended for children 6-12 months is 10 ml when administered orally and 20 ml when administered rectally. A single dose recommended for children 1-3 years old is 15 ml when administered orally and 30 ml when administered rectally. A single dose recommended for children 3-8 years old is 20 ml when administered orally and 40 ml when administered rectally. A single dose recommended for children over 8 years of age and adults is 30 ml when administered orally and 50 ml when administered rectally. In the treatment of purulent-inflammatory diseases and intestinal diseases, as a rule, the appropriate single dose is prescribed three times a day. If, when using a bacteriophage locally, the wound was pre-treated with an antiseptic, it is necessary to wash the wound with a 0.9% sodium chloride solution before using the Piobacteriophage solution. For children under 6 months of age with enterocolitis and sepsis, Piobacteriophage solution is administered in the form of high enemas twice or thrice a day. If the child does not develop regurgitation and vomiting, the drug can be given orally. The average duration of therapy is from 5 to 15 days. As a prophylaxis, the drug is prescribed in a single dose twice a day for 5-7 days.
Storage conditions
In a dry place, protected from light, at a temperature of 28 C
Best before date
2 years
special instructions
Before use, the bottle with liquid bacteriophage must be shaken. If cloudy, do not use!
Conditions for dispensing from pharmacies
Available with prescription
Side effects
No undesirable effects were observed when using the drug Piobacteriophage.
Use during pregnancy and breastfeeding
During pregnancy and breastfeeding, the drug Piobacteriophage can be prescribed by your doctor.
Interaction
The use of the drug is possible in combination with other drugs, incl. with antibiotics.
Overdose
Measures to assist in case of overdose have not been established.
Pyobacteriophage complete liquid 100ml (Microgen)
Pyobacteriophage is intended for local and oral use, as well as for rectal administration. Treatment of purulent-inflammatory processes is recommended through simultaneous local and oral administration of the drug Piobacteriophage. Depending on the location of the infection, Pyobacteriophage is recommended for: 1. Local application in the form of lotions, irrigations, applications and tampons, moistened solutions. In this case, use the required amount of solution based on the size of the affected area. For abscesses, the solution should be injected into the cavity after removing the pus by puncture (the volume of the solution should be slightly less than the volume of the extracted pus). 2. Injection of the solution into the pleural, articular and other limited cavities. After administering the required amount of bacteriophage, capillary drainage is left, through which repeated doses of the drug are subsequently administered. 3. Injection of the solution into the drained cavity of the bladder and renal pelvis through a cystostomy or nephrostomy. 4. Introducing the solution into the uterine or vaginal cavity, including in the form of tampons soaked in the solution. 5. Instillation, washing and rinsing, as well as the introduction of turundas moistened with a solution, in otolaryngological practice. 6. Applications to the conjunctival sac in ophthalmological practice. 7. Insertion of moistened turundas into periodontal pockets in dental practice. 8. Introductions into the rectum in the form of enemas in gastroenterological practice. The dose of the drug Piobacteriophage and the duration of the course of therapy are determined by the doctor. A single dose recommended for children under 6 months is 5 ml when administered orally or 10 ml when administered rectally. A single dose recommended for children 6-12 months is 10 ml when administered orally and 20 ml when administered rectally. A single dose recommended for children 1-3 years old is 15 ml when administered orally and 30 ml when administered rectally. A single dose recommended for children 3-8 years old is 20 ml when administered orally and 40 ml when administered rectally. A single dose recommended for children over 8 years of age and adults is 30 ml when administered orally and 50 ml when administered rectally. In the treatment of purulent-inflammatory diseases and intestinal diseases, as a rule, the appropriate single dose is prescribed three times a day. If, when using a bacteriophage locally, the wound was pre-treated with an antiseptic, it is necessary to wash the wound with a 0.9% sodium chloride solution before using the Piobacteriophage solution. For children under 6 months of age with enterocolitis and sepsis, Piobacteriophage solution is administered in the form of high enemas twice or thrice a day. If the child does not develop regurgitation and vomiting, the drug can be given orally. The average duration of therapy is from 5 to 15 days. As a prophylaxis, the drug is prescribed in a single dose twice a day for 5-7 days.
