Indications for use
The drug is used to treat psychiatric, neurological, and drug-related diseases. It is prescribed in the presence of such pathologies and disorders:
- Alzheimer's disease;
- deterioration of memory and other intellectual functions;
- intoxication;
- various brain injuries;
- headaches;
- dizziness;
- speech problems;
- comatose states;
- pathology of cerebral vessels;
- period of convalescence;
- defective conditions, including schizophrenia;
- nephrotic syndrome;
- lethargy;
- hypochondria;
- depressive states;
- withdrawal syndrome due to alcoholism;
- acute poisoning with certain drugs (including when using barbiturates, morphine);
- sickle cell anemia (as an additional therapy);
- perinatal brain damage (including mental retardation in children, cerebral palsy).
Nootropil is often used in cases of intolerance to antipsychotic drugs. It is used to overcome side effects associated with somatovegetative and neurological complications.
Buy Nootropil solution for internal use 20% 125ml No. 1 in pharmacies
Nootropil Buy Nootropil in pharmacies Nootropil in the drug directory DOSAGE FORMS solution for internal use 20% oral solution 200 mg/ml
MANUFACTURERS NextPharma S.a.S (France) USB S.A. Pharma Sector (Belgium)
GROUP Nootropic drugs
COMPOSITION Active substance - piracetam.
INTERNATIONAL NON-PROPENTED NAME Piracetam
SYNONYMS Lucetam, Memotropil, Nootobril, Noocetam, Piratropil, Piracetam, Piracetam MS, Piracetam Obolenskoe, Piracetam-Akos, Piracetam-Vial, Piracetam-Ratiopharm, Piracetam-Richter, Piracetam-Rusfar, Piracetam-Ferein, Piracetam-E scom, Cerebril, Escotropil
PHARMACOLOGICAL ACTION Pharmacological action is nootropic. Activates associative processes of the brain, improves memory, mood and mentality in healthy and sick people. Increases integrative brain activity and intellectual activity, stimulates learning processes, restores and stabilizes impaired brain functions. Increases the resistance of brain tissue to hypoxia and toxic influences, enhances the synthesis of nuclear RNA in the brain. Improves microcirculation (without vasodilation), blocks platelet aggregation, optimizes the conformational properties of the erythrocyte membrane and the ability of erythrocytes to pass through microvessels. In patients with dementia due to repeated cerebrovascular accidents, it improves the local uptake of oxygen and glucose by brain tissue, and in patients with functional disorders of the central nervous system, it increases the level of wakefulness. Due to its antihypoxic effect, it is effective in complex therapy of myocardial infarction. Reduces the severity of vestibular nystagmus. It is quickly and almost completely absorbed when taken orally. Bioavailability is 100%. Does not bind to plasma proteins. The maximum concentration in the liquor is created after 2-8 hours. Penetrates all organs and tissues, passes the placental barrier. Selectively accumulates in the cerebral cortex, mainly in the frontal, parietal and occipital lobes, cerebellum and basal ganglia. Practically not metabolized. The plasma half-life is 4-5 hours; cerebrospinal fluid - 6-8 hours. Excreted by the kidneys. In patients with renal failure, the half-life is prolonged.
INDICATIONS FOR USE Psychoorganic disorders of vascular, traumatic and toxic origin (comata, acute phase of traumatic brain injury, etc.), psychoorganic syndromes with a predominance of asthenia, decreased attention and thinking abilities (cerebral atherosclerosis, intoxication, alcoholism, etc.), alcohol withdrawal and relief of alcoholic delirium, acute poisoning with morphine and barbiturates, psychosis and asthenodepressive states (complex therapy), flaccid apathetic defective states in schizophrenia, depressive states resistant to antidepressants; in gerontology: memory impairment, dizziness, changes in personality traits, Alzheimer's disease, atherosclerotic discirculatory encephalopathy, post-stroke mental and physical defects; in pediatrics - prevention and treatment of newborn asphyxia, birth trauma and its consequences, the period of convalescence after meningitis, encephalitis, traumatic brain injury, mental retardation, learning difficulties, memory disorders and intellectual disability; correction of side effects and complications of therapy with psychotropic drugs (asthenia, adynamia, neuroleptic crises with hyperkinesis), cortical myoclonus, sickle cell anemia (complex therapy), viral neuroinfections (to reduce the phenomena of hypoxia and cerebral ischemia).
CONTRAINDICATIONS Hypersensitivity, including to pyrrolidone derivatives; hemorrhagic stroke, severe renal dysfunction, pregnancy, breastfeeding, infancy up to 1 year.
SIDE EFFECTS: Dizziness, tremor, nervousness, agitation, incl. sexual, irritability, anxiety, sleep disturbance, weakness, drowsiness, nausea, vomiting, diarrhea, abdominal pain, increased frequency of attacks of coronary insufficiency.
INTERACTION Increases the effectiveness of antidepressants. In old and senile age, it enhances the effect of antianginal drugs and reduces the need for nitroglycerin.
OVERDOSE Symptoms: more pronounced symptoms of side effects. Treatment: symptomatic.
SPECIAL INSTRUCTIONS Caution is required when prescribing to patients with impaired hemostasis, during major surgical operations or patients with symptoms of severe bleeding. When treating patients with cortical myoclonus, abrupt cessation of treatment should be avoided. Exacerbation of coronary insufficiency occurs in elderly patients; in these cases, it is necessary to reduce the dose or discontinue therapy. If sleep disturbances occur, it is recommended to cancel the evening dose and increase the daytime dose. Use with caution while working for vehicle drivers and people whose profession involves increased concentration. Penetrates through the filter membranes of hemodialysis machines.
STORAGE CONDITIONS Store at room temperature, in a dry place.
Contraindications and side effects
The product has few contraindications. Taking Nootropil is completely excluded only in the presence of hemorrhagic stroke and severe kidney pathologies or acute failure. Another indicator of absolute contraindications is individual intolerance to piracetam or other substances included in the tablets, capsules or solution.
Pregnant and lactating women (at any stage) should use Nootropil with caution. Also, careful use is carried out in the presence of chronic diseases, acute conditions that disrupt homeostasis.
In some cases (especially often when the daily norm exceeds 5 g), taking Nootropil gives a number of side effects:
- nausea;
- vomit;
- deterioration in concentration;
- mood swings;
- retardation of movements;
- mental overexcitation;
- sleep problems;
- high level of anxiety;
- appetite disorders;
- gastralgia;
- increased sexual desire;
- headaches;
- tremor;
- dizziness.
Attention!
Taking the medicine may make your angina worse. Patients suffering from this disease should take the drug only under the supervision of a doctor and in accordance with the dosage.
Instructions for use "Nootropil"
The drug is used intravenously (dropper), intramuscularly (injection) and orally. Instructions for using the solution:
- Intravenous injection in the amount of 10 g per day.
- Severe pathology - increase the dosage to 12 g;
- The duration of the droppers is no more than 30 minutes.
- After achieving a stable result, they switch to taking Nootropil tablets or other medications.
Instructions for use of tablets depend on the type of disease and patient’s condition:
- As a general rule, tablets are taken 2 times a day, calculating the dosage in an amount of 30 to 160 g per 1 kg of body weight.
- Memory and attention disorders - 3 times a day, single dose of 1600 mg, then the dosage is reduced by 2 times.
- Cerebrovascular pathologies in the acute stage - initial dosage 12 g per day, after 14 days - 6 g.
- Cortical myoclonus - daily dose is 7.2 g, then daily it is increased by 4.8 g, if necessary, reaching a maximum of 24 g.
- Sickle cell anemia - the dosage is calculated based on the ratio of 160 mg per 1 kg of body weight, taken 4 times a day. The maximum amount is 300 mg per 1 kg of weight.
Attention!
In case of overdose, seek emergency help. The patient is given gastric lavage, vomiting is induced, and hemodialysis is performed if necessary.
Nootropil injection solution 20% 5ml No. 12
Nootropil injection solution 20% 5ml No. 12
Instructions for use Nootropil solution d/in. 20% 15ml No. 12
Dosage forms solution d/in 20% 15ml
Synonyms Lucetam Memotropil Piracetam Group Nootropic drugs International nonproprietary name Piracetam Composition Active substance - piracetam. Manufacturers Krakow Pharmaceutical Plant Polfa (Poland), Pliwa Krakow, Pharmaceutical Plant A.O. (Poland), Polpharma Pharmaceutical Plant (Poland), YUSB S.A. (Belgium), YUSB S.A. Pharma Sector (Belgium) Pharmacological action Pharmacological action - nootropic. Activates associative processes of the brain, improves memory, mood and mentality in healthy and sick people. Increases integrative brain activity and intellectual activity, stimulates learning processes, restores and stabilizes impaired brain functions. Increases the resistance of brain tissue to hypoxia and toxic influences, enhances the synthesis of nuclear RNA in the brain. Improves microcirculation (without vasodilation), blocks platelet aggregation, optimizes the conformational properties of the erythrocyte membrane and the ability of erythrocytes to pass through microvessels. In patients with dementia due to repeated cerebrovascular accidents, it improves the local uptake of oxygen and glucose by brain tissue, and in patients with functional disorders of the central nervous system, it increases the level of wakefulness. Due to its antihypoxic effect, it is effective in complex therapy of myocardial infarction. Reduces the severity of vestibular nystagmus. It is quickly and almost completely absorbed when taken orally. Bioavailability is 100%. Does not bind to plasma proteins. The maximum concentration in the liquor is created after 2-8 hours. Penetrates all organs and tissues, passes the placental barrier. Selectively accumulates in the cerebral cortex, mainly in the frontal, parietal and occipital lobes, cerebellum and basal ganglia. Practically not metabolized. The plasma half-life is 4-5 hours; cerebrospinal fluid - 6-8 hours. Excreted by the kidneys. In patients with renal failure, the half-life is prolonged. Side effects: Dizziness, tremor, nervousness, agitation, incl. sexual, irritability, anxiety, sleep disturbance, weakness, drowsiness, nausea, vomiting, diarrhea, abdominal pain, increased frequency of attacks of coronary insufficiency. Indications for use Psychoorganic disorders of vascular, traumatic and toxic origin (comatose states, acute phase of traumatic brain injury, etc.), psychoorganic syndromes with a predominance of asthenia, decreased attention and thinking abilities (cerebral atherosclerosis, intoxication, alcoholism, etc.), alcohol withdrawal and relief of alcoholic delirium, acute poisoning with morphine and barbiturates, psychosis and asthenodepressive states (complex therapy), flaccid apathetic defective states in schizophrenia, depressive states resistant to antidepressants; in gerontology: memory impairment, dizziness, changes in personality traits, Alzheimer's disease, atherosclerotic discirculatory encephalopathy, post-stroke mental and physical defects; in pediatrics - prevention and treatment of newborn asphyxia, birth trauma and its consequences, the period of convalescence after meningitis, encephalitis, traumatic brain injury, mental retardation, learning difficulties, memory disorders and intellectual disability; correction of side effects and complications of therapy with psychotropic drugs (asthenia, adynamia, neuroleptic crises with hyperkinesis), cortical myoclonus, sickle cell anemia (complex therapy), viral neuroinfections (to reduce the phenomena of hypoxia and cerebral ischemia). Contraindications Hypersensitivity, including to pyrrolidone derivatives; hemorrhagic stroke, severe renal dysfunction, pregnancy, breastfeeding, infancy up to 1 year. Method of administration and dosage : Intravenously. Adults: 1 g 3 times a day, in acute cases - IV or IM up to 10 g/day, gradually reducing the dose. Children 30-50 mg/kg/day in equal doses in several divided doses. The duration of treatment is individual. Overdose Symptoms: more pronounced symptoms of side effects. Treatment: symptomatic. Interaction Increases the effectiveness of antidepressants. In elderly and senile age, enhances the effect of antianginal drugs, reduces the need for nitroglycerin. Special instructions Caution is required when prescribing to patients with impaired hemostasis, during major surgical operations or patients with symptoms of severe bleeding. When treating patients with cortical myoclonus, abrupt cessation of treatment should be avoided. Exacerbation of coronary insufficiency occurs in elderly patients; in these cases, it is necessary to reduce the dose or discontinue therapy. If sleep disturbances occur, it is recommended to cancel the evening dose and increase the daytime dose. Use with caution while working for vehicle drivers and people whose profession involves increased concentration. Penetrates through the filter membranes of hemodialysis machines. Storage conditions Store at room temperature, in a dry place.