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Manufacturers: Jenapharm Gmbh & Co.Kg
Active ingredients
- Norethisterone
- Ethinyl estradiol
Disease class
- Turner syndrome
- Monitoring contraceptive use
- Dysmenorrhea, unspecified
- Female infertility
Clinical and pharmacological group
- Not indicated. See instructions
Pharmacological action
- Contraceptive
Pharmacological group
- Estrogens, gestagens; their homologs and antagonists in combinations
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Combined progestogen-estrogen contraceptive drug with a predominant content of gestagen. It inhibits the gonadotropic function of the pituitary gland, blocks gonadotropin, as a result of which the egg does not mature.
Due to the content of estrogen with gestagen, this drug, with certain regimens of use, stimulates the onset of menstruation or delays it. Helps stop uterine bleeding. A higher than optimal dose of estrogen increases the risk of adverse reactions.
Pharmacokinetics
Ethinyl estradiol is absorbed in the small intestine. The maximum concentration in the blood is after 2 hours. Metabolized to hydroxyl derivatives. It is excreted in the form of metabolites by the kidneys (60%), the rest by the intestines.
Norethisterone acetate is completely absorbed. Its maximum concentration in the blood is determined after 0.5-4 hours. Metabolites are also excreted by the kidneys (60%) and intestines (40%).
Interaction of Non-Ovlon with other drugs
It is necessary to be responsible for the fact that when taking hormonal drugs, a restructuring of the entire hormonal system already occurs, and concomitant diseases can worsen this situation. First of all, before use, you need to inform your doctor about your past illnesses and your decision to use a hormonal-type drug.
Non-Ovlon is contraindicated for combined use with the following medications:
- drugs for the treatment of epilepsy (carbamazepine, topiramate, pyramidone, barbiturates);
- antibiotics (ciprofloxacin, tetracycline, ofloxacin, ampicillin);
- drugs for the treatment of tuberculosis (rifampicin, rifabutin, sodium para-aminosalicylate).
Particular attention should be paid to insulin-dependent people when taking it, since Non-Ovlon reduces the effect of insulin in the blood and can worsen the course of diabetes.
Contraindications
- severe liver disease;
- hormonal tumors (uterus, mammary glands);
- liver tumors;
- diabetes;
- hypercholesterolemia , hyperlipoproteinemia ;
- IHD;
- thromboembolic diseases , thrombosis of veins and arteries;
- phlebeurysm;
- phlebitis;
- cardiovascular diseases;
- hypertonic disease;
- epilepsy;
- sickle cell anemia;
- cerebral vascular diseases;
- otosclerosis;
- multiple sclerosis;
- pregnancy.
Impact on a woman’s body
The formula of the medical product is based on a combination of two female hormones. The medicine is a dark green pellet (21 pieces per package). This combination ensures leveling of the function of the pituitary gland (gland of the brain), which controls the functioning of each ovary. In the normal mode of activity of the pituitary gland, it produces hormones that stimulate the ovaries to form the corpus luteum in them and create eggs.
These pills can both delay menstruation and stimulate its onset. It all depends on the application scheme. They can be used:
- as hormonal contraception;
- to regulate the timing of the onset of menstruation;
- to eliminate uterine bleeding;
- to combat functional or psychological infertility;
- with uterine hypoplasia (its insufficient development);
- to eliminate painful menstruation.
This medical product can also help with irregular uterine bleeding following menstrual irregularities.
Non-Ovlon, instructions for use (Method and dosage)
Non-Ovlon tablets are taken orally for contraception every evening. Reception begins on the 5th day of menstruation and continues for 21 days. The level of hormones in the blood must be constant, so the interval between doses should be 22-26 hours. At the end of the tablets from one package, take a break of 7 days and begin the next cycle of administration (even if bleeding did not occur during the break).
In the treatment of gynecological diseases, the dose of the drug and dosage regimen are prescribed individually according to indications.
Side effects
Like all hormonal drugs, Non-Ovlon has a number of adverse reactions on the woman’s body. These include dizziness, upset stomach, the appearance of dark-colored bleeding between periods, weight gain, swelling and hardening of the mammary glands, increased blood pressure, vomiting, migraine headaches, candidiasis, and chlamydia.
In some cases, when using the medicine, blood counts change, which can give a misleading picture before the onset of some serious illness.
Analogs
Level 4 ATC code matches:
Ovidon
Rigevidon
Mercilon
Yarina Plus
Yarina
Miniziston 20 fem
Novinet
Microgynon
Janine
Lindineth
Cyclo-Proginova
Regulon
Logest
Midiana
Belara
Femoden
Jess Plus
Jess
Zoely
High-dose contraceptive Ovulen , low-dose Trisiston , Triquilar , Triminulet , Femoden , Triaden , Marvelon , Janine , Diane-35 and others.
Hormonal drug analogues
The German company Schering AG stopped producing the hormonal contraceptive Non-Ovlon due to numerous side effects. But reviews from past years indicate that this drug was reliable, potent and loved by the fair sex. It is for this reason that women and girls who previously took it are looking for analogues.
The hormonal contraceptives listed below are analogs of the drug mentioned and have the same ATC code (international nonproprietary name).
Analogues of the drug:
- Jazz.
- Logest.
- Janine.
- Ovidon.
- Minute.
- Diana is 35.
- Noretin.
- Belara.
- Marvelon.
- Miness.
- Novinet.
- Ovosept.
- Rigevidon.
- Femoden.
- Yarina.
They have similar effects and do not cause any particular inconvenience when taken. The regimens for taking the tablets are absolutely identical to those described above, since both the composition and the method of release are similar to the first drug.
Reviews of Non-Ovlon
This drug belongs to monophasic high-dose oral contraceptives, since the content of ethinyl estradiol in one tablet is 50 mcg. In monophasic preparations, the tablets in the package have a constant composition, so when taking them, a woman will have the same estrogen and gestagen content throughout the entire cycle, which is not physiological. In addition, when taking the drug there is a high risk of side effects, especially thrombotic complications, and cholestasis is often observed. Therefore, recently it has not been used for permanent contraception. According to WHO recommendations, low-dose COCs should be used for this purpose, but some doctors “the old fashioned way” recommend Non-Ovlon.
The drug is widely used for the treatment of gynecological diseases: endometriosis, uterine fibroids, polycystic ovary syndrome, dysfunctional uterine bleeding (DUB). This is evidenced by reviews from patients, which state that the drug was prescribed for therapeutic purposes for glandular cystic endometrial hyperplasia, intermenstrual DUB and juvenile uterine bleeding. The treatment lasted 2-3 months and some women noted weight gain, depressed mood, and pain in the right hypochondrium.
The drug, on the recommendation of a doctor, was also used for emergency contraception during unprotected sexual intercourse. In this case, take 2 tablets no later than 72 hours after intercourse and again 2 tablets after 12 hours. Emergency contraception is an alternative to abortion, but it cannot be used permanently.
Many women take Non-Ovlon when their periods are late and possible pregnancy. Most people prefer not to see a doctor; they forget that taking hormonal drugs that can cause spontaneous abortion can lead to bleeding and other complications, including problems with conception in the future. Take 2 tablets every 12 hours until your period appears, which comes in 1-3 days.
When taking Non-Ovlon if your period is late, you should remember that the method is non-physiological and cannot be used more than 1-2 times a year. After taking the drug for this purpose, the menstrual cycle may be disrupted for a long time, and during subsequent periods the discharge may be more abundant.
Similar drugs:
- Midiana Oral tablets
- Diane-35 (Diane-35) Dragee
- Regulon Oral tablets
- Marvelon Oral tablets
- Mirena Intrauterine therapeutic system
- Jeanine (Jeanine) Dragee
- Levonorgestrel Substance-powder
- Lindynette 30 Oral tablets
- Yarina Oral tablets
- Medroxyprogesterone acetate Substance-powder
** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use the drug Non-Ovlon, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.
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** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Non-Ovlon is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!
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Cases in which taking the medicine is not permissible
You should avoid this type of treatment if:
- there are tumors in the area of the mammary glands and uterus;
- there are problems with the functioning of the liver;
- previous pregnancy was accompanied by dermatological problems;
- there is a tendency to cardiovascular diseases;
- disturbances in the functioning of arteries and veins were identified.
In this regard, only after examination by a gynecologist, mammologist, blood tests, and blood pressure monitoring can you, with medical assistance, make a decision on the advisability of using Non-Ovlon. People prone to problems with blood vessels should be careful. Since the medication can aggravate the predisposition to stroke or heart attack, which will be preceded by blockage of blood vessels. This danger increases when:
- smoking abuse;
- overweight;
- high blood pressure;
- blood clotting disorder.
Increased caution should also be present in the case of people with:
- diabetes mellitus;
- epilepsy;
- multiple sclerosis;
- varicose veins;
- diseases affecting the liver.
This medication also tends to negatively affect the condition of the vocal cords. Therefore, it makes sense to refrain from using it for ladies who are:
- singers;
- announcers;
- lecturers;
- teachers.
A decrease in the contraceptive effect of the drug may be preceded by alcohol abuse and illnesses that will accompany vomiting and diarrhea.
