Calcium gluconate, solution 100 mg/ml, ampoules 10 ml, 10 pcs.

Calcium gluconate: what is it and what is it for?

This drug is a dietary supplement that compensates for the lack of calcium in the body. This macronutrient performs a number of important functions:

• promotes the transmission of nerve impulses;
• ensures normal muscle function, and, in particular, the heart muscle;
• part of bones and teeth;
• participates in the process of blood clotting.

Calcium deficiency in the body can lead to a condition such as tetany.

In addition, due to the effect of calcium, such as reducing the permeability of the vascular wall, this drug has an anti-inflammatory and antiallergic effect.

Analogs

The attending physician may prescribe a similar drug that is similar in action instead. Calcium gluconate analogues include:

• “Calcium lactate.”
• “Additive calcium.”
• “CalViv.”
• Hydroxyapatite paste.
• “Calcium-Sandoz forte.”
• “Hydroxyapatite.”

Sources

• https://medside.ru/kaltsiya-glyukonat
• https://gorzdrav.org/p/kalcija-gljukonatsolof-rdi-1010ml10-198432/
• https://Ukol.expert/preparatyi/ukoly-glyukonat-kaltsiya-pokazaniya-k-primeneniyu
• https://lor.guru/procedury/ukoly-glyukonata-kalciya-dlya-chego-naznachayut-vnutrimyshechno.html
• https://oVakcine.ru/inekciya/pokazaniya-k-primeneniyu-ukolov-glyukonata-kaltsiya
• https://uteka.ru/product/kalciya-glyukonat-38943/
• https://apteka.103.by/kaltciya-glyukonat-stabilizirovannij-instruktsiya/
• https://www.rlsnet.ru/tn_index_id_9556.htm
• https://WebApteka.info/kalciya-glukonat-instrukciya-po-primeneniyu/
• https://druggist.ru/431337a-glyukonat-kaltsiya-instruktsiya-po-primeneniyu-v-ampulah-sostav-analogi-i-otzyivyi

When is the drug prescribed?

Experts recommend using this drug for:

• osteoporosis;
• rickets and osteomalacia - conditions in which vitamin D metabolism is impaired;
• increased levels of phosphates in the blood in patients with renal failure;
• presence of high calcium needs: during pregnancy and lactation;
• poor diet;
• bone fractures;
• postmenopausal calcium deficiency;
• chronic diarrhea.

In addition, the drug as a component of complex therapy is used in dermatovenerology for the treatment of itchy dermatoses, urticaria, and angioedema. It is also used for the treatment of bleeding of various etiologies and nutritional dystrophy.

Release form

• tablets 10 pcs. in cell-free contour packages, 1, 2 or 10 packages in a cardboard box;
• chewable tablets 10 pcs. in cell-free contour packages, 1, 2 or 10 packages in a cardboard box;
• solution for intravenous and intramuscular administration. Ampoules 1, 2, 3, 5 and 10 ml, package No. 10.

What is Calcium Gluconate tablets for?

Tablets are recommended for conditions accompanied by hypocalcemia, increased permeability of cell membranes, and disturbances in the conduction of nerve impulses in muscle tissue.

Doctors answer the question “what is calcium gluconate used for?” answer that the use of the drug is advisable for:

• hypoparathyroidism ( osteoporosis , latent tetany);
• vitamin D metabolism ( spasmophilia , rickets , osteomalacia );
• hyperphosphatemia in patients with chronic renal failure;
• increased need for Ca ( pregnancy , breastfeeding , periods of intensive growth in children/adolescents);
• insufficient Ca content in the diet;
• bone fractures;
• Ca metabolism disorders in the postmenopausal period;
• conditions that are accompanied by increased excretion of calcium (chronic diarrhea , prolonged bed rest; long-term treatment with diuretics , corticosteroids or antiepileptic drugs >);
• poisoning with oxalic acid, Mg salts, soluble salts of fluoric acid (the advisability of using the product as an antidote is due to the fact that, interacting with these substances, Ca gluconate forms non-toxic Ca oxalate and Ca fluoride).

As an addition to the main treatment, calcium gluconate tablets are used as a remedy for allergies in pruritic dermatoses , febrile syndrome , urticaria , , , nutritional dystrophy , bronchial asthma , pulmonary tuberculosis , parenchymal hepatitis , eclampsia , nephritis , toxic lesions liver _

Why are calcium gluconate injections used?

Calcium gluconate in ampoules is prescribed for certain pathologies of the parathyroid glands , conditions that are accompanied by increased excretion of Ca from the body, as an adjuvant for allergies , as well as for allergic complications of treatment with other drugs, to reduce vascular permeability in various types of pathological processes, for nephritis , eclampsia , liver intoxication , hyperkalemia , parenchymal hepatitis , hyperkalemic form of periodic paralysis ( paroxysmal myoplegia ), as a hemostatic agent.

Indications (intravenously/intramuscularly) for administration of the drug are also poisoning with soluble salts of fluoric acid, oxalic acid or Mg salts, for skin diseases ( psoriasis, itching, eczema ).

In some cases, Calcium gluconate is used during autohemotherapy . This method of treatment has proven itself well for skin diseases, furunculosis , recurrent colds , diabetes , rheumatism , allergies , and during the recovery period after serious illnesses.

10 ml of calcium gluconate solution is injected into the patient's vein, and then blood is immediately taken from the vein and transferred back in the form of a subcutaneous injection or injection into the gluteal muscle.

Calcium gluconate: intravenous injections

What are the indications for intravenous injection ? The injection is given for certain diseases of the thyroid gland, allergies, liver intoxication, nephritis. Injections are prescribed for hepatitis, vascular permeability, myoplegia and as a hemostatic agent. Intravenous injections are necessary for psoriasis, poisoning, eczema and itching.

The drug helps get rid of boils, skin diseases, diabetes, and chronic colds. For rheumatism, the postoperative period or long-term illnesses, 10 ml of the drug is injected into a vein, then the blood is collected and a subcutaneous injection is performed into the buttock muscle. Children are allowed only intravenous administration, since intramuscular administration causes tissue necrosis.

Calcium gluconate intramuscularly

The doctor may also prescribe intramuscular injections of the drug. The procedure is carried out in the gluteal muscle , because the pain there after the injection is not felt so much. The advantage of intramuscular administration of this drug is the absence of bruises and bumps, rapid penetration into the blood. This method is contraindicated in cases of renal failure, excess calcium in the body, or failure of the lungs and heart.

What is a hot shot?

Injections of the drug are also known as “hot injections of calcium gluconate.” In fact, the solution is administered heated only to body temperature.

A hot injection is called a hot injection because of the subjective sensations that arise in the patient: after the injection, there is usually a feeling of warmth spreading throughout the body, and sometimes a fairly strong burning sensation.

What does a calcium gluconate injection do?

Calcium gluconate injections are best known as an adjuvant treatment for allergic diseases. However, they are also used to treat pathology of the parathyroid gland, in which there is an increased excretion of calcium from the body.

In addition, injections are also prescribed for conditions such as:

• eclampsia;
• nephritis;
• hyperkalemia;
• liver intoxication.

Injections of calcium gluconate help reduce the intensity of itching in atopic dermatitis, psoriasis and eczematous rashes.

Chemical properties

Sodium Gluconate, what is it? It is a salt formed by gluconic acid and sodium. In order to more accurately understand what it is, consider the formula of Sodium Gluconate. Chemical formula of the substance: NaC6H11O7, racemic formula: HOCH2(CHOH)4COONa. The product is highly soluble in ethyl alcohol and water. It is synthesized in the form of transparent small crystals. Molecular mass of chemical compound = 218.1 grams per mole. The product is obtained by the reaction of alkaline fermentation of cellulose.

Sodium Gluconate is used:

• in the manufacture of industrial alkaline detergent compositions as complexing agents;
• in construction to slow down the hardening of concrete and other building mixtures, improve the plasticity of the compositions;
• in the oil industry for cementing, protecting drilling rigs from corrosion and excessive pressure, and loss of moisture;
• in the production of aluminum and steel in the metallurgical industry;
• as a complexing agent and flavor enhancer in the food industry under code E576 .

Using the drug for allergies

If allergic reactions occur, calcium gluconate is a safe and effective remedy, the use of which practically cannot lead to an overdose. When the drug enters the body, the permeability of the vascular wall decreases and the allergen practically does not penetrate into the bloodstream. Thus, the development of an allergic reaction is inhibited. Calcium gluconate can be taken for preventive purposes.

The duration of the course depends on the characteristics of the disease. Calcium gluconate is prescribed by specialists together with antihistamines.

Doses

The daily or monthly dosage of the drug is selected individually for each patient. Only an experienced doctor can correctly determine the required amount of solution, so it is not recommended to self-medicate. The dosage of the solution depends on the following parameters:

• degree of danger of the disease;
• patient's gender;
• age;
• body mass;
• stage of disease development.

Most often, doctors prescribe 5 to 10 ml of solution for adults and 1-5 ml for children. In both cases, only 1 injection per day is allowed. If gluconate is used to maintain Ca levels in the blood, then the frequency of injections is once every 2 or 3 days.

How to give calcium gluconate to children

The drug can be given to children from the first year of life if indicated. At the age of up to 12 months, the optimal daily dose is 3 tablets. Children 1-4 years old are recommended to take 6 tablets per day. Children under 9 years of age can take from 6 to 12 tablets per day, depending on the doctor’s recommendations. Adolescents under 14 years of age can take 12-18 tablets per day.

The daily dose of the drug is divided into 2-4 doses.

Calcium gluconate in the form of a solution is used to treat children of any age as an emergency treatment for severe allergic reactions and the development of bleeding.

Interaction

A drug:

• slows down the absorption of etidronate , estramustine , bisphosphonates , tetracycline antibiotics , quinolones , fluoride and iron preparations for oral administration (an interval of at least 3 hours should be maintained between their doses).
• reduces the bioavailability of phenytoin >;
• enhances the cardiotoxicity of cardiac glycosides >;
• in patients with hypercalcemia , reduces the effectiveness of calcitonin >;
• reduces the effects of calcium channel blockers;
• increases the toxicity of quinidine .

In combination with quinidine, it provokes a slowdown in intraventricular conduction; in combination with thiazide diuretics hypercalcemia increases . Vitamin D and its derivatives help increase calcium absorption. Cholestyramine reduces Ca absorption in the gastrointestinal tract.

Forms insoluble or slightly soluble Ca salts with salicylates, carbonates, and sulfates.

Certain foods (for example, rhubarb, bran, spinach, cereals) can reduce the absorption of Ca from the digestive tract.

Not compatible with the solution:

• carbonates;
• sulfates;
• salicylates;
• ethanol.

For whom the drug is contraindicated

The drug is not used in patients with:

• intolerance to any of the components;
• increased calcium levels in the blood;
• tendency to form blood clots;
• sarcoidosis;
• severe atherosclerosis;
• urolithiasis with the formation of calcium stones.

Calcium gluconate is also not prescribed to patients taking cardiac glycosides.

Contraindications

Hypersensitivity to calcium gluconate and other components of the drug, hypercalcemia (including in patients with hyperparathyroidism, hypervitaminosis D, decalcifying malignancies, renal failure, osteoporosis associated with immobilization, sarcoidosis, milk-alkali syndrome (Burnett's syndrome), hypercalciuria, intoxication cardiac glycosides, simultaneous treatment with cardiac glycosides; for intramuscular administration - children's age.

Carefully:

dehydration, electrolyte disturbances (risk of developing hypercalcemia), diarrhea, malabsorption syndrome, calcium nephrolithiasis (history), slight hypercalciuria, moderate chronic renal failure, widespread atherosclerosis, hypercoagulability, in elderly patients, especially in the presence of one or more of the above conditions, nephrocalcinosis , sarcoidosis, chronic heart failure, simultaneous treatment with epinephrine.

Calcium gluconate solution, packaged in glass ampoules, should not be used for repeated or long-term treatment, including intravenous injection in children under 18 years of age or in persons with impaired renal function.

It is not recommended to use calcium gluconate solution, packaged in glass ampoules, for the preparation of solutions for parenteral nutrition.

Calcium gluconate injections should not be administered concomitantly with ceftriaxone in preterm neonates up to 41 weeks (weeks of gestation + weeks of life) and in full-term neonates (up to 28 days of age) due to the risk of deposition of calcium ceftriaxone in the lungs and kidneys.

Overdose symptoms

With prolonged use of the drug, accumulation of calcium salts in the body is possible. In case of overdose, the following manifestations are observed:

• dyspeptic disorders: constipation, nausea and vomiting;
• increased fatigue and irritability;
• abdominal pain;
• constant thirst;
• muscle weakness and decreased blood pressure.

If these symptoms appear, you must stop taking the drug. Particularly severe cases may require intravenous calcitonin.

Side effect

The incidence of side effects is directly related to the rate of administration and dose of calcium gluconate. When administered correctly, their incidence is less than 1:1000.

From
the cardiovascular system:
decreased blood pressure, bradycardia, arrhythmia, vasodilation, circulatory collapse (including fatal), “flushes” of blood, most often with rapid administration.

From the digestive system:

nausea, vomiting, diarrhea.

General violations:

feeling of warmth, sweating.

Disturbances at the
injection site:
with intramuscular injection - pain or erythema (≤ 1:10, ≥ 1:100), if the intramuscular injection technique is violated - infiltration into adipose tissue with subsequent abscess formation, tissue compaction and necrosis; with intravenous administration - skin hyperemia, burning sensation or pain with the possible development of tissue necrosis (in case of accidental perivascular injection).

Cases of soft tissue calcification with subsequent possible skin lesions and necrosis due to the release of calcium from the vessel into the tissue have been reported.

Best before date

24 months

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The description of vitamin Potassium Gluconate is intended for informational purposes only. Before starting to use any drug, it is recommended to consult a doctor and read the instructions for use. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the project does not replace consultation with a specialist and cannot be a guarantee of the positive effect of the drug you use. The opinions of EUROLAB portal users may not coincide with the opinions of the site Administration.

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