Omnadren 250: reviews, instructions for use, where to buy, price

pharmachologic effect

Omnadren 250 is an androgenic drug that contains a mixture of testosterone esters. This hormone is directly involved in the formation of the testicles, seminal vesicles, prostate gland, and is also involved in the development of secondary and tertiary sexual characteristics. In addition, testosterone determines the formation of the general constitution of the body, as well as a person’s sexual behavior, it helps to increase potency and sexual attraction, activates the process of spermatogenesis, and makes the symptoms of menopause less pronounced in a man.

Testosterone is an antagonist of estrogen , female sex hormones. Under its influence, inhibition of the gonadotropic function of the pituitary gland , and the function of the female mammary glands is suppressed. A patient who is taking a course of the drug may experience masculinization .

Testosterone acts as an anabolic: it accelerates the process of protein synthesis, enhances calcium retention in bone tissue, increases muscle mass, increases hemoglobin in the blood, and activates the production of Erythropoietin in the kidneys.

If exogenous testosterone is administered to a healthy man, he experiences inhibition of the production of endogenous, that is, his own testosterone, as there is a decrease in LH secretion. When high doses of the drug are administered, spermatogenesis is suppressed, since the drug has an effect on the reverse inhibition of FSH secretion .

When treated with testosterone in men who have functional pituitary , there is an increase in the symptoms of hypogonadism . However, if impotence develops due to other reasons other than hypogonadism, treatment with the drug does not eliminate the problem.

Pharmacodynamics

Stimulates protein synthesis, retaining the necessary potassium, sulfur, and phosphorus ions, enhances calcium fixation in bones, and increases muscle mass. Affects the development and function of the external genitalia, prostate gland, seminal vesicles, secondary sexual characteristics (voice, hair). Determines body constitution and sexual behavior, activates libido and potency, stimulates spermatogenesis. It is an antagonist of female sex hormones - estrogens. Reduces the negative manifestations of menopause.

Pharmacodynamics and pharmacokinetics

The testosterone esters contained in Omnadren 250 have different rates of absorption and rates of excretion from the body, due to which the rapid effect and long-lasting effect of the drug (about four weeks) are noted after its one-time administration. If the effect of testosterone propionate occurs during the first day after taking the drug, then testosterone phenylpropionate and isocapronate affect the body only 24 hours after its administration.

Testosterone capronate acts already during the period when the influence of testosterone isocapronate and phenylpropionate is no longer observed.

The drug binds to plasma proteins by 98%. Metabolism occurs in the liver, resulting in the appearance of 17-ketosteroids. After they combine with glucuronic or sulfuric acid, they are excreted from the body in the urine.

90% of the drug is excreted through the kidneys as a metabolite, 6% in an unbound form through the intestines.

The half-life of testosterone from the body is 10-100 minutes.

Indications for use

The drug is indicated for the treatment of men in the following cases:

for post-castration syndrome ;
with eunuchoidism ;
with oligospermia ;
with hypopituitarism ;
with manifestations of male menopause ;
with impotence ;
for infertility ;
with a lack of androgens (this condition is typical for pituitary dwarfism , Addison's disease , adipose-genital syndrome ).

For the treatment of women, the drug is used in the following cases:

with osteoporosis , which develops due to a lack of androgens;
for manifestations of breast cancer ;
for ovarian cancer ;
with hyperestrogenism , accompanied by dysfunctional uterine bleeding;
for endometriosis and uterine fibroids ;
with manifestations of premenstrual tension syndrome ;
for symptoms that accompany menopause ;
for the purpose of virilization of the external genitalia during hermaphroditism .

Contraindications

Treatment with Omnadren 250 should not be carried out if a person has the following diseases or conditions:

suspicion of prostate carcinoma or such an established diagnosis;
hypercalcemia and hypercalciuria ;
gynecomastia;
heart, kidney or liver failure;
asthenia;
use for the treatment of elderly men and prepubertal boys;
pregnancy and breastfeeding;
high level of sensitivity to the product.

Side effects

The following side effects may occur during treatment:

In the functions of the endocrine system: women may note the development of dysmenorrhea , masculinization , hirsutism , slowdown in gonadotropin secretion; men may notice impaired spermatogenesis , the development of oligospermia , gynecomastia , priapism ; When treating boys, puberty may be too active.
In the functions of the reproductive system: disturbance of human libido.
Skin reactions: the appearance of acne , male pattern baldness
In the functions of the digestive system: development of nausea , manifestation of liver tumors , cholestatic jaundice , hepatic purpura , impaired liver function.
In blood coagulation processes: slowing down the activity of a number of plasma coagulation factors, the manifestation of bleeding in people who take drugs with anticoagulant effects.
In the functions of the central and peripheral nervous system: manifestation of headaches, paresthesia, fear.
In the process of metabolism: an increase in the level of cholesterol in the blood plasma.
Local reactions and pain may occur in the area where the injection is given.

Harm and benefits of omnadren in bodybuilding

Initially, the drug was invented for the treatment of “male diseases”, but athletes were interested in it for the following reasons:

The drug Omnadren 250 after administration has an anabolic and androgenic effect. That is, it helps to increase muscle mass, strength, endurance, reduce the amount of subcutaneous fat, increase the “hairiness” of the body, and generally improve the overall well-being of a man.
Like many steroids, this one has a side effect of flooding. Water acts as a lubricant for joints, reducing their “dry” friction. This effect will be appreciated by a good half of bodybuilders, lifters and weightlifters, since most athletes have problems with joints.
Like most anabolic steroids, Omnadren regenerates muscle tissue, which is useful for muscle injuries. Accelerates the body's recovery after heavy physical exercise. loads

The price of a prescription drug is 600 rubles, so many can purchase it and use it thoughtlessly and uncontrollably. Hence the possible side effects and harm to health.

Omnadren damage:

Omnadren 250 has an antagonistic effect on the female body: it inhibits the normal functioning of the pituitary gland and suppresses the development of the mammary glands. Regular use of the product causes masculinization in women. Whether this is good or bad is a questionable question.
Well-known side effects in the form of possible gynecomastia from aromatization of the test in estradiol, acne, increased blood pressure, hematocrit, liver enzymes are also present in Omnadren.
The introduction of an exogenous hormone very strongly, if not completely, inhibits the production of one’s own testosterone.
Deterioration of psycho-emotional state, manifestation of aggressiveness.
We consider pouring water to be a plus, but this effect can also bring negative effects in the form of hypertension, swelling, the appearance of bags under the eyes and overload of the kidneys.

Instructions for use of Omnadren 250 (Method and dosage)

The instructions for Omnadren 250 stipulate that the patient is prescribed 1 ml of the drug once every 28 days. You should ask your doctor in detail how to inject the drug, but according to the instructions it is injected intramuscularly, deep into the gluteal muscle. The dosage is determined by the attending physician; it depends on the indications, as well as the patient’s response to the administration of the drug.

Instructions for use of Omnadren 250 stipulate that for primary male hypogonadism, the drug is administered intramuscularly once every 7 or 14 or 21 days. The frequency of administration depends on the degree of insufficiency of the patient's gonads.

During menopause in men, it is practiced to administer Omnadren 250 once every 14 days; after the effect of treatment becomes noticeable, it is necessary to switch to administering the drug once every 21 days.

For male infertility, Omnadren 250 is administered in a dose of 2 ml once every 14 days. If a man experiences pain in the penis during erection during therapy, treatment should be stopped.

During menopause , a woman is prescribed 1 ml once every 14 days or 21 days.

For or breast cancer, 1-2 ml is administered once every 7 or 14 days for a long period.

Interaction

If patients receive oral anticoagulants in parallel with treatment with Omnadren 250, it is necessary to constantly carefully monitor blood clotting parameters.

In people suffering from diabetes , when taking androgen drugs, a decrease in blood glucose levels may also occur, and there may also be a need to use insulin.

If Omnadren 250 is used at the same time as ACTH or GCS, the risk of developing peripheral edema increases, in particular in those people who suffer from liver disease or diseases of the cardiovascular system.

The effects of testosterone may decrease when combined with the drug and taking drugs that provoke the induction of microsomal liver enzymes .

special instructions

The drug should not be administered intravenously.

During androgen treatment, patients with breast cancer may develop hypercalcemia due to stimulation of osteolysis . This may increase metastasis in the skeletal system. If treatment with Omnadren 250 is prescribed to a woman, it is necessary to monitor the concentration of calcium in the blood serum.

If androgen drugs are prescribed in large doses, it is necessary to constantly monitor the hemoglobin content and hematocrit.

If the patient shows signs of hepatitis, jaundice develops, liver function indicators change, the drug must be discontinued, the diagnosis and etiology of such changes must be established. It is important to carefully monitor liver function tests.

When treated with the drug in older men, the likelihood of developing prostate cancer and hypertrophy increases. It is important to conduct a prostate examination before starting treatment and during the treatment process, as well as monitoring PSA levels.

The drug should be discontinued if a person has kidney, liver, cardiovascular diseases, as well as peripheral edema.

Treatment with Omnadren is carefully prescribed to 250 patients who experience delayed puberty . In such people, it is important to monitor the condition of the skeletal system every six months.

When using Omnadren 250 as a doping, severe side effects may occur.

Treatment with the drug does not affect the ability to drive vehicles and operate serious machinery. Concentration may decrease if a person develops heart failure.

Dosages of Omnadren

Objectively, for constant positive dynamics in mass and strength, an average-level athlete will need 250 mg of the drug per week - this is one injection. Over time, it will be possible to increase the dosage to 500 mg per week.

In addition, it should be borne in mind that Omnadren-250 is still not a drug for the “first course”. This is due to the fact that it is not very convenient to use alone due to the almost complete absence of a “smooth entry” into the course. At the first injection, a fairly large dose of the substance is introduced into the body, often excessive for the needs of a “freshman”.

And yet, if I had nothing in my nightstand other than Omnadren, I would use it as reflected in the table.
Regimen for taking Omnadren - 250 as the only drug in the course of AAS
At the dosages shown in the table, side effects are insignificant. But the results are quite acceptable. And after stopping the drug, there is a chance to save most of them. In addition, the relative “smoothness” of both the beginning of the course and the exit from it can be traced.

Analogues of Omnadren 250

Level 4 ATC code matches:
Methyltestosterone

Sustanon 250

Androgel

Nebido

Andriol

Testosterone Isocaproate

Testosterone Decanoate

Testosterone Phenylpropionate

Testosterone Cypionate

Testosterone Undecanoate

Testosterone Enanthate

In terms of active ingredients, analogues of Omnadren 250 are the drugs Sustanon-250 , Tetrasterone , Testenate . If we evaluate the mechanism of action, then analogues of the drug can be called Nebido , Andriol TK , Testosterone propionate , Methyltestosterone , Androgel . All of these drugs can be used to treat diseases only after approval by a doctor.

Which is better: Omnadren or Sustanon?

The drugs Sustanon and Omnadren are similar both in composition and in their effectiveness on the human body. However, patients note that Sustanon has a milder effect on the body. It is also noted that when treated with Sustanon, side effects are less pronounced.

conclusions

Omnadren - 250 is one of the most powerful drugs for gaining mass and strength in powerlifting and bodybuilding, but it is desirable that the benefits of taking it be greater than the harm:

Purchase the drug either from “trusted people” or in pharmacies.
Do not exceed reasonable dosages.
Since the drug aromatizes easily, take an antiestrogens (for example, Proviron) to reduce the associated unwanted side effects. This will also help reduce the accumulation of excess water.
Omnadren - 250 is absolutely contraindicated for women.

In conclusion, I would like to note that Omnadren - 250 is often considered an analogue of Sustanon - 250. We will try to figure out how similar these drugs are in the next article.

Reviews of Omnadren 250

There are different reviews about Omnadren 250 on the Internet. In particular, those patients who were treated with this drug note the manifestation of some side effects associated with the characteristics of the drug.

It is noted that with prolonged treatment, problems with liver function, water retention in the body, the appearance of severe acne on the skin, etc. were observed. In addition, due to the availability of this product (it is offered not only in regular pharmaceutical chains, but also sold by almost any online pharmacy ) some users inject large doses, trying to achieve results in actively building muscle mass. Due to serious excess of dosage, negative manifestations are observed.

Omnadren 250[edit | edit code]

Yuzhakov Anton Testosterone description of the drug

Omnadren 250 from Jelfa Ukrainian version Polish packaging

Omnadren 250

(Omnadren-250, “omka”) is an anabolic steroid from the Polish pharmaceutical company Jelfa SA

Since August 16, 2014, Omnadren has been banned

, since a new list of drugs for subject-quantitative accounting has come into force, [1] and unaccounted circulation is prohibited. To purchase it at a pharmacy, you need a prescription form, form N 148-1/у-88. Due to decreased availability, the price of Omnadren has increased more than 7 times. This is due to the fact that the sale of the drug has become much more difficult, the shortage of the product has sharply increased, so prices have increased in proportion to the risks and decreased availability. In 2021, the price is actually equal to Sustanon (about $4 per 1 ml ampoule). The fall in the ruble exchange rate was also reflected.

Omnadren 250 contains 4 testosterone esters of different duration of action:

Main substances:

testosterone propionate – 30 mg;
testosterone phenylpropionate – 60 mg;
testosterone isocapronate – 60 mg;
testosterone decanoate – 100 mg;

Result: total testosterone content 176 mg from 250 mg testosterone + ester tail.

Excipients :

Peanut oil - to dissolve testosterone crystals + ether tail in it.
Benzyl alcohol - disinfects the oil solution.
Nitrogen - to create an inert environment by displacing oxygen from the ampoule.

The price in European pharmacies for Sustanon 250 and Omnadren 250 is identical; in Russia, until the end of 2015, the Ministry of Health of the Russian Federation, at the expense of the budget, bought 80% of the cost of the drug.

Produced until the end of 2015 in cardboard packages of 5 ampoules. Since the end of 2015, it has been produced in cardboard packaging with one ampoule.

Omnadren 250 is absolutely identical to the drug Sustanon 250 (manufactured under license by the pharmaceutical company Jelfa SA - Poland).

Description[edit | edit code]

Omnadren is testosterone combined with four different esters, the resorption time of which explains the fact that the drug tends to linger in the body for a long period after administration. The drug Sustanon-250, with which Omnadren is often compared, also has similar properties.

The scope of application of Omnadren is primarily bodybuilding and powerlifting, where the drug provides athletes with the necessary increase in muscle mass and strength. Omnadren, due to the accumulation of water in the body, ensures a rapid and high-quality increase in body weight, which, however, is also characteristic of other testosterones. Athletes who have been taking Omnadren for a long time are already familiar with pumping during training. Due to the strong anabolic and androgenic effects of the drug, not only the accumulation of water in the body, which alleviates joint pain, and an increase in strength are achieved, but also increased appetite, higher tissue regeneration and the “pump effect”, well known to athletes.

Contraindicated in liver failure, renal failure, hypercalciuria, blood and cardiovascular diseases. Quite often, swelling, acne, inflammation at injection sites, prostate hypertrophy, and gynecomastia develop. In rare cases, symptoms of hepatitis, development of jaundice, and decreased blood clotting may occur. Liver function should be monitored. Before prescribing, consultation with a doctor is required.

Scheme of application and dose:

Despite the fact that Omnadren 250 lingers in the body for a long time, athletes prefer to inject it weekly. The dosage of the drug can be different; Omnadren is one of the few injectable steroids, the dosage of which can be either 250 mg of the drug per week or 1000 mg per day. Although, as practice shows, the optimal dosage of the drug will be 500 mg of Omnadren per week, intramuscularly. To achieve more noticeable and faster results, athletes sometimes combine this drug with Deca Durabolin, Methandrostenolone or Anadrol. A good result is obtained by the combination of Omnadren and Methandrostenolone, which is not only effective and provides a rapid increase in muscle and strength with a minimum of energy costs, but also has a low price, which makes it accessible to most athletes. One of the few disadvantages of Omnadren is, perhaps, the fact that after stopping taking the drug, the volume of muscle mass and the achieved strength gain decline.

It is worth paying attention to the fact that the composition of Omnadren in Russia and Ukraine has a difference, which is the fourth ester of testosterone (information as of 2017). On the territory of Ukraine, Omnadren has the following composition: propionate, phenylpropionate, isocapronate and caproate, while on the territory of the Russian Federation - propionate, phenylpropionate, isocapronate and decanoate. Caproate and decanoate have different half-lives, which fundamentally affects the interval between injections[2].

Due to pronounced aromatization (conversion into estrogens), it is necessary to use aromatase inhibitors throughout the entire course (to prevent edema and gynecomastia).

More details:

Side effects of steroids and how to reduce the harm of steroids

Price Omnadren 250, where to buy

You can buy Omnadren 250 in Moscow pharmacies or order the drug in other cities at a price of 500 to 600 rubles per package of 5 ampoules. If you order the product from an online pharmacy, the price of Omnadren with delivery will be slightly higher. But this is the easiest way to purchase this medicine in Perm, as well as in other cities of Russia (Ekaterinburg, Chelyabinsk, etc.). Where to buy Omnadren 250 in St. Petersburg, you should find out on the websites of specific pharmaceutical chains, as well as at retail pharmacy outlets.

Online pharmacies in UkraineUkraine
Online pharmacies in KazakhstanKazakhstan

Pharmacy24

Omnadren 250 1 ml N5 solution Pharmaceutical plant Elfa A.T., Polshcha
641 UAH. order

Cons of Omnadren

Firstly, these are the side effects, the same as those of testosterone propionate:

Liver problems;
Acne;
Increased pressure;
Gynecomastia, aggressiveness;
Water retention;
Significant suppression of the production of own testosterone.

Secondly , the price and availability of Omnadren – 250. Yes, it is the price and availability that are the main disadvantages of this drug. The fact is that Omnadren is on the list of vital drugs, and even in our difficult times it can be easily purchased in pharmacies. Especially in private ones. The cost of a standard (5 ampoules) ranges from 500 to 700 rubles.

Needless to say, with such a price and “easily accessible”, Omnadren is poured in liters. Some people inject 8-10 ampoules a day, which is 2000-3000 mg. active substance.

It is the excess of all reasonable dosage limits that causes those monstrous acne that covers Omnadern users almost from head to toe with a single crust. And it is from such doses that a person “floods with water” to the point of swelling of the face and bags under the eyes.

What if other AAS are taken in parallel with Omnadren? So it turns out that after using a cocktail of androgenic-anabolic steroids in a very high dosage and receiving a whole “bouquet” of side effects, the user begins to criticize Omnadren. Because they produce it in Poland, without proper quality control, and they counterfeit it all and sundry. You might think that in Pakistan or India, production is sterile, and there is nothing fake...