Cerucal in ampoules for children with vomiting dosage

When not to

The medicine has contraindications, so giving it to a child without a doctor’s prescription is dangerous. Children who have:

epilepsy;
glaucoma;
bleeding from the gastrointestinal tract;
intestinal obstruction;
pheochromocytoma (a tumor that activates excessive production of adrenaline or norepinephrine);
extrapyramidal (motor) disorders;
gastric perforation (for example, with peptic ulcer);
peritonitis.

And, of course, patients with hypersensitivity to any of its components should not take the medicine. The drug is not prescribed to children under 2 years of age.

With caution, only under the supervision of a doctor and careful monitoring of changes in the child’s condition, the drug is indicated for patients with certain pathologies:

liver and/or kidney dysfunction;
bronchial asthma;
hypertonic disease.

Actually, childhood itself is the reason for a particularly attentive attitude towards the patient who is prescribed Cerucal. These factors increase the risk of side effects.

No amateur performances! Only a doctor can prescribe the drug for your child.

Contraindications

For asthma, hypertension and problems with the kidneys and liver, the drug should be taken with caution and under the supervision of a doctor. It is also worth seeing a doctor when young children take the drug due to the high risk of dyskinetic syndrome.

In older people, with long-term use of Cerucal in large dosages, extrapyramidal disorder may be a side effect.

During the period of use, you should avoid activities that require concentration and rapid psychomotor reactions.

Among the contraindications it is also worth noting the following:

hemorrhages in the gastrointestinal tract;
obstruction in the intestines;
epilepsy;
breast-feeding;
glaucoma;
Parkinson's disease;
high sensitivity and intolerance to metoclopramide.

For a more complete understanding of the application features, you should read the instructions.

What does it treat indications for use?

nausea and vomiting;
prolonged and frequent hiccups;
bile duct dyskinesia;
gastric pyloric stenosis;
duodenal stenosis;
gastric paresis (relevant for those suffering from diabetes);
decreased tone of the gastrointestinal tract elements (intestines, stomach);
flatulence.

Pediatricians often recommend taking the drug on the eve of diagnostic studies of the stomach and/or intestines. The use of Cerucal for nausea and vomiting caused by disorders of the vestibular apparatus or psychogenic factors is often ineffective.

The indication for use of the medicine is uncontrollable vomiting.

Interaction with other drugs

When taking other medications with Cerucal, it is important to know that this drug:

incompatible with alkaline solutions for infusion;
together with antipsychotics can aggravate movement disorders;
in combination with sedatives increases the likelihood of Parkinson's syndrome;
accelerates the absorption of antibiotics;
quickly destroys vitamin B1;
enhances hepatotoxicity (effect on the liver) of drugs with this property.

Such opportunities to change the effect of other medications are another reason for the danger of self-medication with Cerucal.

At what age is it prescribed?

In the form of injections, Cerucal can be used in children over 2 years of age, since the liquid form allows you to accurately dose the active substance of the drug. In this case, for children aged two to 14 years, injections are used only as prescribed by a doctor, and if any side effects occur, the medication is immediately discontinued. Most often, such injections are used as an emergency remedy that helps stop vomiting, hiccups or nausea of various origins.

The tablet drug is not used in the treatment of patients under 14 years of age. This is due not only to the solid form (problems with swallowing), but also to a greater risk of overdose.

Compatibility with other drugs

"Cerucal" in solution should not be mixed with drugs for infusions that have an alkaline environment. Under the influence of "Cerucal", the effect of anticholinesterase drugs is reduced, and the absorption of cimetidine, paracetamol, some antibiotics, digoxin, levodopa and lithium preparations is enhanced. When combined with drugs that depress the central nervous system, their effect on the brain will be stronger.

If Cerucal is prescribed together with antipsychotics, the risk of extrapyramidal disorders will increase. When treated with Cerucal, the effectiveness of antihistamines may decrease. If this medicine is used with hepatotoxic drugs, the likelihood of liver damage increases. When used simultaneously with vitamin B1, a rapid breakdown of thiamine is observed.

Combination of Cerucal with other medications

Cerucal, when administered intravenously, improves the absorption of Diazepam and increases its content in plasma.

Use with:

anticholinergic drugs - weakens the effect of both drugs;
neuroleptics - increases the risk of extrapyramidal reactions;
Ethanol, Paracetamol and Aspirin - improves their absorption;
Zopiclone - improves the absorption of this drug;
Mexiletine and Mefloquine - improves their absorption and increases their content in the blood plasma.

When using Cerucal, before using Propofol and Thiopental, you will need to reduce their induction dosages.

More information about release forms and packaging

Cerucal is available in the form:

tablets;
solution for injection.

The solution in ampoules is administered intravenously or intramuscularly.

Blisters with white tablets are packed in cardboard boxes (50 tablets per package). Each tablet contains 10 mg of the active substance - metoclopramide hydrochloride. The solution for intramuscular and intravenous injection is sold in two-milligram ampoules with the same content of the active ingredient as in tablets - 10 mg (5 mg of metoclopramide per 1 ml of medicine).

Both forms of Cerucal provide the same therapeutic effect. The tablets have a prolonged effect (up to 6 hours), and therefore they are often prescribed in the complex treatment of chronic pathologies of the gastrointestinal tract. But the drug administered intramuscularly or intravenously does not act for so long - only about 2 hours. But the effect after the injection occurs much faster than after taking the pill.

Cerucal injections are usually prescribed in cases of urgent need to relieve symptoms of indigestion, as well as in case of vomiting, which does not allow the tablet to stay in the stomach for at least 20 minutes.

Instructions for use

The drug in tablets should be taken before meals (about half an hour) and washed down with 100-200 ml of water. It is not recommended to bite the medicine or crush it in any other way. "Cerucal" injections can be administered in two ways:

Intramuscularly. With this method, the injection is performed in a place where muscle tissue is well developed (shoulder, thigh, buttock). In addition, the injection site is periodically changed to prevent local adverse reactions.
Into a vein. Usually, the drug is administered in a stream using this method, but the injection should be performed slowly. Droppers are also sometimes prescribed for 15 minutes. To do this, the required dose of Cerucal is dissolved in 50 ml of a 5% glucose solution or 0.9% sodium chloride solution.

The permissible dosage of Cerucal for children under fourteen years of age is calculated based on body weight. Typically, children are prescribed medication in solution at a rate of 0.1 mg/kg. Injections are given 1 to 4 times a day, and the maximum dosage can be 0.5 mg/kg. For example, a child’s weight is 20 kg, then for one dose he needs 2 mg of metoclopramide (0.1x20), which corresponds to 0.4 ml of solution, and per day such a patient can be given 10 mg of the drug (0.5x20), that is one ampoule.

Dosages of Cerucal for a teenager over 14 years of age will be slightly higher, but they differ from adult doses. If injections are used, then such a patient is given 10 mg of the active substance at a time, which corresponds to 1 ampoule. Such injections are given one to three times a day.

When a solid form is prescribed in adolescence, a single dosage can be either half a tablet (it is carefully divided according to risk) or a whole tablet. The frequency of administration, unlike for adults, is no more than 3 times a day. The maximum single dosage for a teenager 14-18 years old is 10 mg (one tablet or one ampoule), and the daily dosage is 30 mg (three tablets or 6 ml of solution).

If the drug is prescribed before examining the upper digestive tract, it is used once - 10 minutes before the procedure. A child 2-13 years old is given a slow intravenous injection (the solution is administered over one to two minutes) at a dose of 0.1 mg/kg, and a teenager over 14 years old is slowly injected into a vein with mg of the active substance - a solution from one or two ampoules.

Cerucal indications for use

Indications for the use of the drug include nausea and vomiting caused by various reasons:

radio and chemotherapy;
liver dysfunction;
migraine;
toxicosis (except for late pregnancy).

The drug also effectively copes with nausea caused by taking medications. It is prescribed as a prophylaxis against vomiting before medical diagnostics, often before gastroscopy (swallowing “guts”).

However, it does not have proven effectiveness and is not used to reduce nausea of vestibular origin.

There is no need to use Cerucal for gastric paresis, dyspepsia, or overeating.

How to take Cerucal for vomiting

Adults - 5-10 mg 3-4 times a day. For vomiting and severe nausea, the drug is administered intramuscularly or intravenously at a dose of 10 mg. It is also possible to use the solution intranasally - 10-20 mg in both nostrils 2-3 times a day.

Limit doses:

single dose orally - 20 mg;
daily - 60 mg for any methods of administration.

For children over 6 years of age, the average dose is 2.5–5 mg 1–3 times a day. For children under 6 years of age, the daily dose is no more than 1 mg/kg 1–3 times a day.

How does it work

The main active ingredient in Cerucal is metoclopramide hydrochloride. It blocks the functioning of receptors through which impulses from irritated areas of the gastrointestinal tract (stomach and duodenal mucosa) are transmitted to the vomiting center of the brain. As a result, the gag reflex is suppressed.

Another direction of action of the drug is to increase the tone of the smooth muscles of the stomach. This helps to increase the speed at which food enters the intestines. At the same time, the drug stimulates the protection of the esophagus from the reflux of stomach contents into it, and the stomach from the entry of bile into it. That is, the medicine prevents such unpleasant symptoms as belching and heartburn. At the same time, Cerucal has a positive effect on intestinal motility, which ensures timely emptying and eliminates another common childhood (and not only) problem - constipation.

The drug helps overcome nausea and revitalizes the gastrointestinal tract.

Note!

The description of the drug Cerucal on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.

Side effects

The likelihood of an overdose and the occurrence of adverse reactions after using the medicine depends on the age of the patient. If the instructions and doctor's recommendations are not followed, pathological changes are possible in:

Nervous system. Increased fatigue, weakness, dizziness, drowsiness, tics of the facial and neck muscles, speech disorders.
Blood supply. Decrease in the content of granulocytes in the leukocyte formula.
Gastrointestinal tract. Defecation disorders (constipation or diarrhea), dry mouth.
Cardiovascular system. Changes in blood pressure, increased heart rate.
Hormonal background. Gynecomastia in boys or menstrual irregularities in girls during puberty.
Immunity. Allergic reactions in the form of skin rash or bronchial asthma.

Most often, adverse reactions affect the central and peripheral nervous systems in childhood. The child develops manifestations of phobias, increased anxiety, and mood swings. In case of kidney and liver diseases, injections provoke an increase in the production of ALT and AST enzymes and increase the synthesis of bilirubin.

Young children may respond to treatment with Cerucal with dyskinetic syndrome. This condition is characterized by uncontrolled contraction of the muscles of the face, shoulders and neck. The pathology does not pose a threat to the baby’s life, but interferes with normal social adaptation in the team.