Instructions for use
pharmachologic effect
The therapeutic effect of Tribux is explained by the beneficial properties of its active component - trimebutine. This substance binds to opioid receptors and normalizes the motility of the digestive system. Trimebutine acts on the smooth muscles of the gastrointestinal tract, but has no effect on the central nervous system.
It is noteworthy that Tribux compares favorably with medications containing codeine and morphine. Unlike them, it affects muscles in two directions: it simultaneously stimulates and inhibits the peristalsis of the gastrointestinal tract. The product begins to act quite quickly: the effect becomes noticeable after 30 minutes. after taking the pill.
Indications for use
Before use, consult your doctor. In therapeutic practice, Tribux is prescribed quite often. The following problems may be the basis for prescribing this drug:
- irritable bowel syndrome, characterized by impaired gastrointestinal motility (the standard symptom is the appearance of pain before and during bowel movements);
- gastroesophageal reflux or, more simply, heartburn;
- various functional gastrointestinal disorders, such as constipation, diarrhea, stabbing pain in the intestines or stomach, etc.
Despite the listed indications, doctors recommend not taking the drug without consulting a doctor. Especially if the pain in the intestines or stomach is not one-time, but systematic. This symptom may indicate the presence of serious diseases of the gastrointestinal tract.
Mode of application
The drug Tribux is recommended for use in adult patients and children over the age of twelve. As for the dosage, it is determined by the age of the patient:
- Adults are recommended to take 1 tablet of Tribux (equivalent to 100 mg trimebutine) three times a day. In special cases, patients are transferred to taking 4-6 tablets per day at regular intervals (with the doctor’s permission).
- For children over 12, the dose is selected based on body weight. It is recommended to give no more than 6 mg of the drug per 1 kilogram of weight.
Tribux tablets are intended for oral use. They are swallowed whole, without chewing, and washed down with boiled water. The manufacturer of the drug emphasizes that before taking Tribux you should consult your doctor regarding the dose and duration of treatment. If you have any doubts, you should contact your doctor again.
Release form, composition
A drug intended to regulate the functioning of the muscles of the gastrointestinal tract, Tribux is supplied to pharmacies in the form of hard tablets of 100 mg. The manufacturer packages the tablets in blisters and cartons. One pack may contain 60, 30 or 20 tablets.
The active component of Tribux is trimebutine maleate. In addition to the active ingredient, the drug contains several auxiliary ingredients, namely: modified starch, microcrystalline cellulose, lactose monohydrate, magnesium stearate.
Interaction with other drugs
Tribux can actively interact with most medications, so before taking the pills, you must tell your doctor about all the medications you are currently taking (even those sold in pharmacies without a prescription).
Thus, parallel use of Zotepine may provoke an increase in anticholinergic effect. In turn, trimebutine is able to prolong the effect of d-tubocurarine.
All gastroenterology clinics and medical centers in your city. Tests and ultrasound. Consultation with a gastroenterologist. Diseases of the digestive system. Find out more: - In Kiev (Hertz, Ilaya, Euromed) - In St. Petersburg (SM-Clinic, Longevity, Allergomed, Doctor +, BaltZdrav, Professor) - In Moscow (SM-Clinic, Medlux, Onmed) - In Kharkov ( TsMEI, Olympic, Victoria, Fortis, Ecomed) - In Minsk (Belgirudo, Art-Med-Company, Sinlab, Mikosha, GrandMedica, MedClinic) - in Odessa (Medea, On Clinic, Into Sano, Venus) - In Razyan (Trust + , Polyclinic-Pesochnya, Evrikas +) - in Nizhny Novgorod (Only Clinic, Alpha Center, EuroClinic, SOLO, Altea) - gastroenterological clinics of Tyumen (Doctor A+, Clinic "Vera", Avicenna, Medis, Sibirina, Your Doctor)
Instructions for use Tribux tablets (tablets): description, composition, FTG, INN
Hypersensitivity to the active substance or any of the auxiliary components.
Cautions for use
Before you start taking TRIBUX®, you should discuss this with your doctor or pharmacist.
TRIBUX ®
contains lactose monohydrate.
If the patient has previously been diagnosed with intolerance to certain sugars, he should consult a doctor before taking this medicine.
Using the drug TRIBUX ®
with food and drink
Tablets should be taken before meals with a glass of boiled water.
Drug interactions and other types of interactions
It is important to inform the doctor or pharmacist about all medications you are currently taking, those you have recently taken, and those you plan to take.
The doctor should be especially informed if the patient is taking any of the following medications:
zotepine (an antipsychotic drug), d-tubocurarine (a muscle relaxant used for general anesthesia), cisapride (a medicine used for stomach problems), procainamide (a medicine used for heart problems), calcium channel antagonists (medicines used for hypertension and heart disease), captopril (a medicine used for hypertension), reserpine (a medicine used for hypertension), midazolam (a medicine used for sleep disorders).
Pregnancy and lactation period
If you are pregnant or breastfeeding, think you may be pregnant, or are planning to become pregnant, you should consult your doctor or pharmacist before using this medicine.
Pregnancy
There is not enough data on the use of trimebutine during pregnancy, so the use of TRIBUX® in the first trimester of pregnancy is not recommended. The medicine can be used in the second and third trimesters of pregnancy only if absolutely necessary.
Lactation
TRIBUX® can be used by breastfeeding women only when absolutely necessary.
Use of the drug TRIBUX ®
in children and adolescents
The use of the drug TRIBUX ® in children under 12 years of age is not recommended, since the available form of the drug (tablets) does not allow choosing the appropriate dose.
Impact on the ability to drive vehicles and control moving mechanisms
The drug TRIBUX®, taken in accordance with the recommended dosage, does not affect the ability to drive vehicles, maintain machines and does not reduce psychophysical activity. However, given the possibility that, at the beginning of treatment, some patients may develop adverse reactions such as drowsiness and dizziness, which may affect the ability to carry out activities requiring concentration, caution should be exercised when driving vehicles and engaging in other potentially hazardous activities.
Directions for use and dosage
TRIBUX® should be taken as recommended by your doctor. If in doubt, consult your doctor or pharmacist.
Adults
1
tablet 3 times a day
before meals.
In exceptional cases, the doctor may increase the dose to 6 tablets per day,
dividing them into doses.
Use in children and adolescents
Children and adolescents over 12 years of age
TRIBUX® can be used in children at a dose not exceeding 6 mg/kg body weight per day.
Children under 12 years old
The use of TRIBUX® in this age group is not recommended (see section “Use of TRIBUX® in children and adolescents”)
Mode of application
The tablets should be swallowed whole, without chewing,
with a glass of boiled water.
Duration of treatment
The doctor determines individually.
Overdose
If you take more than the recommended dose, you should immediately contact your doctor, pharmacist or the nearest hospital.
If you miss the next dose of TRIBUX medication®
Do not take a double dose to make up for a missed dose.
If you miss the next dose, you must take the next dose of the medicine at the prescribed time.
Interruption of taking the drug TRIBUX®
If you have any further doubts regarding the use of the medicine, you should consult your doctor or pharmacist.
Side effects
Among the side effects observed during treatment with Tribux are the following adverse reactions:
- Digestive system: poor taste discrimination, indigestion, nausea, dry mouth, stomach pain, constipation, diarrhea.
- Nervous system: dizziness, drowsiness, fever or chills, headaches.
- Allergic reactions: skin rashes.
Problems associated with urination (delay), menstrual irregularities, temporary hearing impairment, anxiety, swelling and tenderness of the breasts in women were extremely rarely observed.
Overdose
As for an overdose, the same side effects appear, but more pronounced. Patients who notice symptoms of overdose should immediately contact their doctor or pharmacist. Therapy in this case is aimed at removing the drug from the stomach (using lavage), as well as eliminating the side effects that appear (symptomatic therapy).
To avoid an accidental overdose, it is worth understanding one important thing: making up for a missed dose with a double dose is strictly prohibited. You can take the pill only if there is enough time left before the next dose.
If you take more than the recommended dose of the medicine, you should immediately consult your doctor or pharmacist, or go to the nearest hospital
Contraindications
There are practically no contraindications to taking Tribux. Like other drugs, it is prohibited for people with intolerance to certain components of the drug (especially trimebutine), as well as a predisposition to allergic reactions.
Due to the lack of sufficient data on the use of trimebutine during pregnancy, it is not recommended to take the drug
During pregnancy
Independent use of Tribux (without consulting a doctor) during pregnancy is contraindicated, because this may negatively affect the child's health. In the first trimester, the drug is completely prohibited for use.
It is sometimes prescribed in the third and second trimesters, but in small doses and in cases of extreme need. These recommendations should be followed despite the fact that animal studies have not revealed embryotoxic, teratogenic or mutagenic effects of Tribux on the embryo.
As for nursing mothers, they also try to protect them from taking Tribux, because the effect of the drug on nursing patients and their children has not been fully studied. It follows from this that during lactation the drug is prescribed in cases of extreme necessity.
Tribux tablets 100 mg No. 10x3
Name
Tribux
Description
Round biconvex tablets of white or almost white color, with acceptable inclusions.
Main active ingredient
Trimebutine
Release form
A cardboard pack containing 2, 3 or 6 blisters of 10 tablets, along with an insert.
Dosage
100 mg
Indications for use
— Irritable bowel syndrome. — Functional disorders of the digestive tract, accompanied by abdominal pain, cramps, a feeling of fullness, flatulence, constipation or diarrhea.
Directions for use and doses
TRIBUX® should be taken as recommended by your doctor. If in doubt, consult your doctor or pharmacist. Adults 1 tablet 3 times a day before meals. In exceptional cases, the doctor may increase the dose to 6 tablets per day, dividing them into doses. Use in children and adolescents Children and adolescents over 12 years of age TRIBUX® can be used in children at a dose not exceeding 6 mg/kg body weight per day. Children under 12 years of age The use of TRIBUX® in this age group is not recommended (see section “Use of TRIBUX® in children and adolescents”) Method of administration The tablets should be swallowed whole, without chewing, with a glass of boiled water. The duration of treatment is determined by the doctor individually. If you miss the next dose of TRIBUX®, you should not take a double dose to make up for the missed dose. If you miss the next dose, you must take the next dose of the medicine at the prescribed time. Interruption of taking TRIBUX® If you have any further doubts regarding the use of the medicine, you should consult your doctor or pharmacist.
Use during pregnancy and lactation
If you are pregnant or breastfeeding, think you may be pregnant, or are planning to become pregnant, you should consult your doctor or pharmacist before using this medicine. Pregnancy There is not enough data on the use of trimebutine during pregnancy, therefore the use of TRIBUX® in the first trimester of pregnancy is not recommended. The medicine can be used in the second and third trimesters of pregnancy only if absolutely necessary. Breastfeeding TRIBUX® can be used by breastfeeding women only when absolutely necessary.
Precautionary measures
Before you start taking TRIBUX®, you should discuss this with your doctor or pharmacist. TRIBUX® contains lactose monohydrate. If the patient has previously been diagnosed with intolerance to certain sugars, he should consult a doctor before taking this medicine. Using TRIBUX® with food and drink Tablets should be taken before meals with a glass of boiled water. Use of the drug TRIBUX® in children and adolescents The use of the drug TRIBUX® in children under 12 years of age is not recommended, since the available form of the drug (tablets) does not allow choosing the appropriate dose. The drug TRIBUX®, taken in accordance with the recommended dosage, does not affect the ability to drive vehicles, maintain machines and does not reduce psychophysical activity. However, given the possibility that, at the beginning of treatment, some patients may develop adverse reactions such as drowsiness and dizziness, which may affect the ability to carry out activities requiring concentration, caution should be exercised when driving vehicles and engaging in other potentially hazardous activities.
Interaction with other drugs
It is important to inform the doctor or pharmacist about all medications you are currently taking, those you have recently taken, and those you plan to take. The doctor should especially be informed if the patient is taking any of the following drugs: • zotepine (an antipsychotic drug), • d-tubocurarine (a muscle relaxant used for general anesthesia), • cisapride (a medicine used for stomach problems), • procainamide (a medicine , used for heart problems), • calcium channel antagonists (medicines used for hypertension and heart disease), • captopril (medicine used for hypertension), • reserpine (medicine used for hypertension), • midazolam (medicine , used for sleep disorders).
Contraindications
Hypersensitivity to the active substance or any of the auxiliary components.
Compound
Active ingredient: one tablet contains 100 mg of trimebutine maleate. Excipients: lactose monohydrate, microcrystalline cellulose, povidone, crospovidone, magnesium stearate.
Overdose
If you take more than the recommended dose, you should immediately contact your doctor, pharmacist or the nearest hospital.
Side effect
Like all medicines, TRIBUX® can cause side effects, although not everyone gets them. The following side effects may occur when taking TRIBUX®: Often (in 1 to 10 per 100 people) • drowsiness, lethargy, • feeling tired, • dizziness, • feeling warm or cold, • headache, • apathy, • dry mouth. , • taste disturbance, • diarrhea, • indigestion, • pain in the epigastric region, • numbness of the lips, • nausea, • vomiting, • constipation, • thirst. Uncommon (1 to 10 per 1,000 people) • rash. Rarely (in 1 to 10 per 10,000 people) • heart rhythm disturbances, • liver dysfunction, including an increase in the activity of the liver enzymes ALT and AspAT in the blood. Very rare (less than 1 in 10,000 people, including isolated cases) • restlessness, • hearing loss, • hepatitis, • skin changes (itching, urticaria, redness, blisters, papules, exudation, erythema), • delay urination, • menstruation disorder, • painful breast enlargement in women, • breast enlargement in men (gynecomastia), • pain in the chest area.
Storage conditions
Do not take the drug after the expiration date. Keep the drug out of the reach of children. Store at a temperature of 15°C - 25°C. Shelf life is three years from the date of production.
Buy Tribux tablet 100 mg in bl. in pack No. 10x3 in the pharmacy
Price for Tribux tablet 100 mg in bl. in pack №10x3
Instructions for use for Tribux tablet 100 mg in bl. in pack №10x3
Reviews
Most Tribux reviews found on medical forums are positive. Patients claim that the effect of the drug is felt almost immediately, and there are no side effects when using the medication. According to doctors who prescribed Tribux to their patients, taking the drug led to the rapid elimination of symptoms of impaired gastrointestinal motility. The only drawback of the drug is its rather high price. In addition, many people complain that finding medicine in Russian and Ukrainian pharmacies is quite problematic.
Real reviews of Tribux are at the end of the article. Add your own to the existing reviews if you have ever taken this product. Believe me: the readers of our resource will thank you for this.
