Orvis immuno 125 mg 12 pcs. film-coated tablets
pharmachologic effect
Antiviral immunostimulating agent and inducer of interferon formation.
Composition and release form Orvis immuno 125 mg 12 pcs. film-coated tablets
1 tablet contains:.
- Active substance: tilorone dihydrochloride (tilorone) - 125.00 mg.
- Excipients: calcium hydrogen phosphate (disubstituted calcium phosphate anhydrous) - 78.00 mg. microcrystalline cellulose - 76.00 mg, croscarmellose sodium - 15.00 mg. povidone K-30 - 3.00 mg. magnesium stearate - 1.50 mg, stearic acid -1.50 mg.
- Excipients of the shell: hypromellose (hydroxypropyl methylcellulose) - 6.17 mg, titanium dioxide - 1.85 mg, macrogol 4000 (polyethylene glycol 4000) - 1.24 mg. polysorbate 80 - 0.62 mg, sunset yellow dye - 0.12 mg.
6 tablets per blister pack made of polyvinyl chloride film and flexible packaging made on the basis of aluminum foil. .
1 blister pack along with instructions for use is placed in a cardboard pack.
Description of the dosage form
The tablets are round, biconvex, orange film-coated; on a cross section, the core is orange interspersed with white and orange.
Directions for use and doses
The drug is taken orally after meals. .
For the treatment of influenza and other acute respiratory viral infections - 125 mg per day for the first 2 days of treatment, then 125 mg after 48 hours. Per course - 750 mg (6 tablets). .
For the prevention of influenza and other acute respiratory viral infections - 125 mg once a week for 6 weeks. Per course - 750 mg (6 tablets). .
For the treatment of herpes infection - the first two days, 125 mg, then after 48 hours, 125 mg. The course dose is 1.25-2.5 g (10-20 tablets). .
When treating influenza and other acute respiratory viral infections, if symptoms of the disease persist for more than 4 days, you should consult a doctor.
Pharmacodynamics
Low molecular weight synthetic interferon inducer that stimulates the formation of all types of interferons in the body (alpha, beta, gamma and lambda). The main producers of interferon in response to the administration of tilorone are intestinal epithelial cells and hepatocytes. T lymphocytes, neutrophils and granulocytes. After oral administration, the maximum production of interferon is determined in the sequence intestine-liver-blood after 4-24 hours. Tiloron has an immunomodulatory and antiviral effect. .
Induces the synthesis of interferon in human leukocytes. Stimulates bone marrow stem cells, depending on the dose, enhances antibody formation, reduces the degree of immunosuppression. restores the ratio of T-suppressors and T-helpers. Effective against various viral infections, including influenza viruses, other acute respiratory viral infections, hepatitis viruses and herpes viruses. The mechanism of antiviral action is associated with inhibition of the translation of virus-specific proteins in infected cells, as a result of which viral reproduction is suppressed.
Pharmacokinetics
After oral administration, it is quickly absorbed from the gastrointestinal tract. Bioavailability - 60%. About 80% of the drug binds to plasma proteins. The drug is excreted almost unchanged through the intestines (70%) and through the kidneys (9%). Half-life (T½) - 48 hours.
The drug does not undergo biotransformation and does not accumulate in the body.
Indications for use Orvis immuno 125 mg 12 pcs. film-coated tablets
As part of complex therapy in adults: treatment of influenza and other acute respiratory viral infections; treatment of herpes infection. Prevention of influenza and ARVI in adults.
Contraindications
- hypersensitivity to tilorone and other components of the drug;
- pregnancy and breastfeeding;
- children under 18 years of age.
Application of Orvis immuno 125 mg 12 pcs. film-coated tablets during pregnancy and breastfeeding
The use of the drug during pregnancy is contraindicated. If it is necessary to use the drug during lactation, breastfeeding should be discontinued.
special instructions
The drug does not have a negative effect on the ability to perform potentially hazardous activities that require increased attention and speed of psychomotor reactions (driving a car and other vehicles, working with driving mechanisms, working as a dispatcher, operator, etc.).
Overdose
There are no known cases of drug overdose.
Side effects Orvis immuno 125 mg 12 pcs. film-coated tablets
Allergic reactions, dyspepsia, short-term chills are possible. If any of the side effects indicated in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.
Drug interactions
Compatible with antibiotics and drugs for traditional treatment of viral and bacterial diseases. No clinically significant interaction of tilorone with antibiotics and traditional treatments for viral and bacterial diseases, or alcohol was detected.
Orvis Broncho
Release form
The solution for oral administration and inhalation is transparent, colorless to brown, with a slight characteristic odor.
Compound
Active ingredient : ambroxol hydrochloride (7.5 mg/1 ml).
Excipients : sodium chloride, sodium hydrogen phosphate dihydrate, citric acid monohydrate, benzalkonium chloride, purified water.
Pharmacological group
Mucolytic and expectorant drug. Secretolytics and stimulants of motor function of the respiratory tract.
Action
Mucolytic agent with expectorant action. Ambroxol increases the secretion of the glands of the respiratory tract, stimulates the activity of the villi of the respiratory tract, and enhances the formation of surfactant in the lungs. Ambroxol is a metabolite of bromhexine.
Ambroxol - description of the substance
The effect occurs 30 minutes after administration and lasts 6-12 hours.
Indications
Diseases of the respiratory tract, accompanied by the production of viscous sputum and difficulty in sputum discharge:
- acute and chronic bronchitis;
- pneumonia;
- bronchial asthma;
- bronchiectasis;
- COPD
Contraindications and restrictions
- I trimester of pregnancy, hypersensitivity to ambroxol.
Carefully
- Impaired bronchial motility and increased mucus secretion (for example, with rare immotile cilia syndrome);
- renal failure and/or severe liver failure;
- peptic ulcer of the stomach and duodenum (including a history);
- II and III trimesters of pregnancy;
- children under 2 years of age (oral solution; only as prescribed by a doctor).
Application and dosage
Inside
The drug is taken after meals, added to water, tea, milk or fruit juice. During treatment, it is necessary to drink plenty of fluids (water, tea, juice) to enhance the mucolytic effect of the drug.
- Adults and children over 12 years of age : the first 2-3 days, 4 ml (100 drops) 3 times a day (which corresponds to 90 mg of ambroxol per day), then 4 ml 2 times a day (which corresponds to 60 mg of ambroxol per day) .
- Children from 6 to 12 years old : 2 ml (50 drops) 2-3 times a day (which corresponds to 30 or 45 mg of ambroxol per day).
- Children from 2 to 6 years old : 1 ml (25 drops) 3 times a day (which corresponds to 22.5 mg of ambroxol per day).
- Children under 2 years : 1 ml (25 drops) 2 times a day (which corresponds to 15 mg of ambroxol per day).
- For children under 2 years of age, the drug is prescribed only under the supervision of a doctor.
Maximum daily dose when taken orally: for adults - 90 mg; for children 6–12 years old - 45 mg; for children 2–6 years old - 22.5 mg; for children under 2 years old - 15 mg.
Inhalations
- Adults and children over 6 years of age : 1-2 inhalations of 2-3 ml (50-75 drops) of solution per day (which corresponds to 15-45 mg of ambroxol per day).
- Children under 6 years of age : 1-2 inhalations of 2 ml (50 drops) of solution per day (which corresponds to 15-30 mg of ambroxol per day).
The drug can be used using any modern equipment for inhalation (except steam inhalers). To achieve optimal hydration during inhalation, the drug is mixed with 0.9% sodium chloride solution in a ratio of 1: 1. Since during inhalation therapy, a deep breath can provoke a cough, inhalation should be carried out in normal breathing mode. Before inhalation, it is usually recommended to warm the inhalation solution to body temperature. Patients with bronchial asthma are recommended to carry out inhalation after taking bronchodilators to avoid nonspecific irritation of the respiratory tract and their spasm.
If symptoms of the disease persist within 4-5 days from the start of treatment, it is recommended to consult a doctor.
Storage
Store in a dry place, protected from light, at a temperature not exceeding 25 °C. Shelf life - 3 years, after opening - 6 months.
Production
JSC "EVALAR" (Russia)
Package
50 or 100 ml in an orange glass bottle, bottle in a cardboard pack complete with a measuring cup.
Recipe
Available without a prescription.
The drug Evalar Orvis Immuno - reviews
Milena Lapina
https://otzyvy.pro/reviews/otzyvy-orvis-immuno-316847.html
I also take it for prevention and when I am sick. Although with this medicine this now rarely happens. Inexpensive and quite effective. I often travel on business trips, and I always have to be on my feet, there’s no time to get sick.
Love
https://www.otzyvua.net/orvis-immuno-evalar
Now I use this medicine for prevention, I only need to take 1 tablet per week, but the benefits are great, the package is enough for the full course. In a pandemic, I consider medicine generally necessary
Alina Bashkova
https://otzovik.com/review_8398355.html
Advantages:
the price for an immunomodulator is small - 500 rubles
Flaws:
No
My body itself has been weak since childhood, I was constantly sick and as an adult I also suffered constantly, I took sick leave because of which I changed more than one job. Orvis immuno attracted with its inexpensive price (relative to antiviral drugs, it costs 500 rubles). I use it regularly, even if the course falls during warm weather, I don’t neglect it, the fact is that, as you know, you need to prepare a sled in the summer, the same with immunity, the body must be prepared before the cold, and not during it, then you will get sick less . I know what I’m talking about, thanks to Orvis, I get sick at most once a year and not severely, mainly during the flu period, when everyone infects each other... and this is me, a person who has never left the hospital before!
CoughChehe
https://otzovik.com/review_9205988.html
Advantages:
convenient to use
Flaws:
No
I used to pass by antiviral drugs, but recently I started thinking about it. My work involves constant business trips and I have to change my plans very drastically when I get sick. Now I take antiviral drugs without waiting for the disease itself, so to speak, in courses, for prevention. And these are not necessarily the autumn-winter periods with outbreaks of influenza and ARVI, but in the summer I maintain my immunity at its best. Evalar’s Orvis Immuno helps me with this. They are sold in many pharmacies in the city, and I have never had to go somewhere special to buy them. A pack of six tablets costs about 500 rubles. Not cheap on the one hand, but if you get sick you will have to shell out more money and spend a lot of time on recovery. One course lasts six weeks. During this time you need to take only one tablet per week. I try to do this on the same day. For me it's Monday. Over the entire period of use, which is two years of use, I began to get sick much less, and the disease does not proceed as “vigorously” as before. I think this is the merit of these tablets; antiviral tablets perfectly protect our body.
Victoria
https://otzyvy.pro/reviews/otzyvy-orvis-immuno-316847.html
A doctor once told me that if at the beginning of the season of high incidence of acute respiratory viral infections I take an antiviral drug, it will act as a vaccination against acute respiratory viral infections and influenza as well. This year I found Orvis Immuno Evalara and I was attracted by the fact that it is a medicine, and not just a dietary supplement, like many antiviral drugs, it has a normal price and is convenient to take - only 6 tablets are needed per course. I can say that the medicine showed its effectiveness, I didn’t get particularly sick all winter, a slight runny nose doesn’t count.
Yulia1207
https://otzovik.com/review_7875031.html
Advantages:
Quick effect
Flaws:
A bit expensive
I took it for my husband, the temperature subsided after the first dose of the drug. The next day I began to feel much better, it is convenient to take it once a day. Large list of indications. I gave it to the children once a week as a preventive measure, and during the winter they never got sick. I really liked it.
Chamomile-
https://otzovik.com/review_7246859.html
Advantages:
low price, you need to take it once a week
Flaws:
everyone has their own vision. There are no cons for me
I have been actively using antiviral drugs for a long time, I used to use them only when I was sick, in order to recover faster, now I have become smarter and drink for prevention, this helps to avoid a lot of problems, since I can’t get sick at all! I found Orvis Immuno in a pharmacy, bought it for 400 rubles, before that I tried to take Kogacel, but it was a bit expensive, and it was inconvenient to constantly think about pills, I often forgot to take it. With Orvis, the intake is much simpler - once a week. There are 6 tablets in a package, enough for a course of 6 weeks. While I was using it, I didn’t get sick and now I feel great. I bought it for my husband and eldest daughter as a preventive measure so that they wouldn’t bring the infection into the house from their robots! The main active ingredient in these tablets is tiloron; this substance induces the production of interoferons (the body's defense against viruses), and Kogacel also has the same properties. The only difference is in price and ease of use. Orvis may not be suitable for some, since taking it once a week may not be very convenient, but it’s more convenient to take it every day... see for yourself. antivirals, especially in the autumn-winter period, you need to drink, since there are a lot of viruses now, as soon as you go to the shopping center, you immediately catch something if the body is not protected.
