Magnelis B6 Forte film-coated tablets. 100mg+10mg 60 pcs

Magnelis B6 forte tablets 100 mg + 10 mg No. 30

A country

Russia
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Active substance

Magnesium citrate + Pyridoxine

Compound

Active ingredients: magnesium citrate, pyridoxine hydrochloride.

pharmachologic effect

Pharmacodynamics. Magnesium is a vital element that is necessary for the normal functioning of cells and is involved in most metabolic reactions. In particular, it is involved in the regulation of the transmission of nerve impulses and muscle contraction. 50% of the amount of magnesium contained in the body accumulates in bone tissue. Pyridoxine (vitamin B6) is involved in many metabolic processes, helps improve the absorption of magnesium from the gastrointestinal tract and its penetration into cells. Serum magnesium concentration: between 12 and 17 mg/l (1 - 1.4 mEq/l or 0. 5 - 0.7 mmol/l): indicates moderate magnesium deficiency; Below 12 mg/L (1 mEq/L or 0.5 mmol/L): indicates severe magnesium deficiency. The body receives magnesium through food. A lack of magnesium in the body can occur with a deficiency in intake or with an increase in the need for magnesium. Pharmacokinetics: Gastrointestinal absorption of magnesium salts occurs partially through a passive mechanism in which the solubility of the salt plays a decisive role. The degree of this absorption does not exceed 50%. Excretion occurs primarily by the kidneys.

Indications for use

Established magnesium deficiency, isolated or associated with other deficiency conditions, accompanied by symptoms such as increased irritability, minor sleep disturbances, gastrointestinal cramps, rapid heartbeat, increased fatigue, muscle pain and spasms, and a tingling sensation in the muscles. If after a month of treatment there is no improvement in these symptoms, continuing treatment is not advisable.

Mode of application

The tablets should be taken whole with a glass of water. Adults: 3-4 tablets per day, divided into 2-3 doses, with meals. Children over 12 years of age: 2-4 tablets per day, divided into 2-3 doses. during meals.Usually the duration of treatment is one month.

Interaction

Before prescribing other medications, you should consult with your doctor about the possibility of taking them simultaneously with the drug. Contraindicated combinations: With levodopa: the activity of lsvodone is inhibited by lyridoxine (if this drug is not combined with the use of peripheral aromatic L-amino acid decarboxylase inhibitors). Any amount of pyridoxine should be avoided unless levodopa is taken in combination with peripheral aromatic L-amino acid decarboxylase inhibitors. Combinations not recommended: Concomitant use of drugs containing phosphates or calcium salts may impair intestinal absorption of magnesium. Combinations to consider. When prescribing tracyclines orally, it is necessary to maintain an interval of at least three hours between ingestion of tetracycline and Magnelis B6 forte, since magnesium preparations reduce the absorption of tetracyclines.

Side effect

Immune system disorders: Very rare: allergic reactions, including skin reactions; Gastrointestinal disorders: Unknown frequency: diarrhea, abdominal pain, nausea, vomiting, flatulence.

Contraindications

Hypersensitivity to any of the components of the drug; severe renal failure (creatinine clearance less than 30 ml/min); age under 12 years (efficacy and safety have not been established); hereditary galactosemia, glucose and galactose malabsorption syndrome or lactase deficiency (due to the presence of composition of the drug lactose monohydrate); simultaneous administration of levodopa.

Overdose

Symptoms: With normal kidney function, an overdose of magnesium when taken orally usually does not lead to toxic reactions. However, in case of renal failure, magnesium poisoning may develop. Symptoms of overdose, the severity of which depends on the concentration of magnesium in the blood: decreased blood pressure; nausea, vomiting; depression of the central nervous system, decreased reflexes; changes in the electrocardiogram; respiratory depression, coma, cardiac arrest and respiratory paralysis; anuric syndrome. Treatment. Rehydration, forced diuresis. In case of renal failure, hemodialysis or peritoneal dialysis is necessary.

special instructions

With caution. Moderate renal failure (risk of developing hypermagnesemia). Use during pregnancy and lactation. Pregnancy. Clinical experience with the use of a combination of magnesium citrate and pyridoxine hydrochloride in a sufficient number of pregnant women did not reveal any adverse effects on the occurrence of fetal malformations or fetotoxic effect. The drug can be used during pregnancy only if necessary, on the recommendation of a doctor. Breastfeeding period. Taking into account that magnesium passes into breast milk, if it is necessary to take the drug, it is recommended to stop breastfeeding. The drug is intended only for adults and children over 12 years of age. The drug contains lactose monohydrate, therefore its use is not recommended for patients with hereditary galactosemia, glucose-galactose malabsorption syndrome or lactase deficiency. In case of moderate renal failure, the drug should be taken with caution due to the risk of developing hypermagnesemia. With simultaneous deficiency of calcium and magnesium, magnesium deficiency should be replenished before starting to take calcium supplements or dietary supplements containing calcium. When pyridoxine is used in high doses (more than 200 mg per day) for a long time (over several months or in some cases years), sensory axonal neuropathy may develop, which is accompanied by such symptoms such as numbness and impaired proprioceptive sensitivity, tremor of the distal limbs and gradually developing sensory ataxia (impaired coordination of movements). These disorders are usually reversible and disappear after stopping taking vitamin B6.

Magnelis B6

Magnesium is involved in ensuring the most important biochemical and physiological processes in the body, affects energy, plastic, electrolyte metabolism, and is involved in the work of about 300 enzymes. Magnesium deficiency increases the risk of developing cardiovascular, neurological, gastroenterological diseases, and diabetes. Frequent manifestations of Magnesium deficiency are: irritability, anxiety, chronic fatigue, sleep disturbances, headaches, spasms and muscle pain.

A good supply of Magnesium to the body protects it from destructive stress. In just 10 minutes of stress, the daily requirement of Magnesium is burned. And in pregnant women, Magnesium deficiency aggravates the risk of miscarriage, therefore magnesium and vitamin B6 preparations are widely used in obstetric and gynecological practice (in the complex therapy of miscarriage, for the prevention of preeclampsia).

• Magnelis B6 contains a complex of Magnesium lactate and vitamin B6, which ensures their easy absorption.
• Vitamin B6 increases the absorption of Magnesium in the intestines, improves its entry into cells and accumulation in them.

Magnesium is involved in the activation of pyridoxine in the liver.

Composition: Magnesium lactate 470 mg (equivalent to magnesium content 48 mg) + pyridoxine 5 mg

Indications for use

established magnesium deficiency, isolated or associated with other deficiency conditions.

Question answer

Is it possible to take magnesium supplement (Magnelis B6) during pregnancy?

According to the instructions for medical use, pregnancy is not a contraindication to the use of magnesium preparations. The decision on the duration of taking a drug containing magnesium lactate 470 mg and pyridoxine hydrochloride 5 mg should be made by the attending obstetrician-gynecologist based on an assessment of your condition (for example, if there is increased uterine tone in the early stages of pregnancy, higher doses are usually prescribed than in later stages , if magnesium preparations are prescribed to prevent gestosis).

I am pregnant, and the gynecologist prescribed me a magnesium supplement. Magnesium is known to relieve spasms, does this affect overall blood pressure? Is it possible to use magnesium with initially low blood pressure if it was prescribed by a gynecologist?

Magnesium does not have a direct hypotensive effect, so it is not contraindicated in the presence of low blood pressure. The need to take magnesium or other medications should be decided by the attending physician, obstetrician-gynecologist and therapist after additional examination.

During pregnancy I have been experiencing leg cramps. Is this related to magnesium deficiency?

Clinical manifestations of magnesium are often increased anxiety, irritability, increased uterine tone, leg cramps, sleep disturbances and many others. The phenomenon you describe may be due to magnesium deficiency, and taking magnesium supplements can help eliminate it. The question of the advisability of using magnesium preparations and dosages can be decided by your attending physician.

Hello. Will a magnesium supplement help you carry out a pregnancy? The last 2 pregnancies ended in birth at 36 and 38 weeks.

Due to the fact that magnesium is involved in the regulation of neuromuscular transmission, taking magnesium preparations helps normalize muscle tone, including magnesium preparations used for increased uterine tone. However, in the later stages of pregnancy, the use of complex therapy is indicated to prevent premature birth, and in some cases hospitalization in a hospital is indicated. In each case, the prescription of therapy is individual, so I recommend that you discuss this issue again with your obstetrician-gynecologist.

Good afternoon The period is 23 weeks, from the first weeks I have been taking Magnelis B6. Now I wanted to start taking calcium. They say it doesn't mix well with magnesium. At what interval is it better to take these drugs?

To avoid interactions between calcium and magnesium preparations, it is advisable to maintain an interval between their doses of at least 6 hours; the optimal regimen is the following: magnesium preparations in the morning, and calcium preparations in the evening, before bedtime.

Can I take magnesium supplements during lactation?

According to the instructions for medical use of the drug Magnelis B6, magnesium passes into breast milk, so use of the drug should be avoided during lactation and breastfeeding.

Is there a need for a time interval between taking Magnelis and taking iron supplements?

To avoid interactions between iron and magnesium preparations (Magnelis B6), it is advisable to maintain an interval between their doses of at least 2 hours.

How can an overdose of magnesium affect the condition of the fetus?

Magnesium supplements during pregnancy are prescribed by your doctor. When prescribing them, the clinical manifestations of a deficiency of this microelement and the characteristics of the course of your pregnancy should be taken into account, which allows you to avoid an overdose of magnesium. Typically, magnesium preparations are prescribed in prophylactic or therapeutic doses that do not exceed the daily requirement for magnesium (it is 400 mg, and increases significantly during pregnancy).

The new formula Magnelis® B6 forte (Magnesium + Vitamin B6) contains 2 times more magnesium and vitamin B61.

• The first Russian analogue of the French drug with the highest concentration of Magnesium + B6!2
• The only 3 large package No. 60*! It lasts a long time!
• Affordable price!

The optimal formula for better absorption of the mineral and convenient administration!

Compound

Magnesium citrate 618.43 mg (equivalent to magnesium content 100 mg) + pyridoxine 10 mg.

Indications

established magnesium deficiency, isolated or associated with other deficiency conditions, accompanied by symptoms such as increased irritability, minor sleep disturbances, gastrointestinal cramps, rapid heartbeat, increased fatigue, pain and muscle spasms, tingling sensation in the muscles. If after a month of treatment there is no improvement in the symptoms of magnesium deficiency, continuing treatment is not advisable.