pharmachologic effect
Lavomax tablets have an immunomodulatory and antiviral effect.
The active component stimulates the production of interferons in the body. After the administration of Lavomax, interferon is produced mainly by hepatocytes, intestinal epithelial cells, neutrophils, and T-lymphocytes.
After the antiviral drug Lavomax has been taken orally, the highest degree of interferon production occurs as follows: intestines-liver-blood. This process begins after 4-24 hours. Under its influence, brain stem cells are stimulated, antibodies , and the degree of immunosuppression is reduced. There is also a restoration of the T-helper/T-suppressor ratio.
Wikipedia shows that the medicine demonstrates effectiveness against a variety of viruses, including influenza , hepatitis , herpes , neurotropic viruses, and cytomegaloviruses .
The mechanism of its influence is associated with the process of inhibiting the translation of virus-specific proteins in those cells that have been infected. As a result, viral reproduction is suppressed.
Pharmacology
The medication has an antiviral and immunomodulatory effect. After oral administration, interferon is produced to a greater extent as follows: intestines-liver-blood. The process starts after 5-22 hours.
Doctors assure that the drug is effective against various microorganisms.
The active substance is quickly absorbed from the stomach. Bioavailability approximately 55%. To a greater extent, it comes out together with feces in its original form. A small part is excreted in the urine. The half-life is two days.
Indications for use
The instructions for the drug define the following indications for the use of Lavomax in adult patients:
- viral hepatitis A, B, C;
- cytomegalovirus infection;
- herpetic infection;
- viral and infectious-allergic encephalomyelitis
- tuberculosis ;
- nongonococcal urethritis;
- respiratory and urogenital chlamydia ;
- influenza and ARVI .
Lavomax is used as part of complex treatment.
additional information
Shelf life is 24 months from the date of release of the drug. It should be stored at room temperature, in a dry and dark place out of reach of small children.
Lavomax does not affect the ability to drive a vehicle or operate other mechanisms that require increased concentration.
The product is not an antibiotic, it only has an antiviral effect.
Interactions with other drugs have not been determined.
You should not take Lavomax in parallel with alcoholic drinks, since the interaction of ethanol and the drug may cause asthenia, and your health will deteriorate greatly. This may lead to allergic reactions. In addition, the effect on immunity will be negative.
Lavomax tablets, instructions for use
According to the instructions for use of Lavomax, the tablets should be taken after meals.
Patients with influenza and ARVI are prescribed 125 mg of Lavomax in the first 2 days, then 125 mg every other day. A total dose of 750 mg is used throughout the course of treatment.
To prevent influenza and ARVI, you need to take 125 mg of Lavomax once a week for six weeks.
For the treatment of viral hepatitis A, 125 mg of the drug is prescribed twice a day, after which you need to take 125 mg of the drug every other day. The total dose per course is 1.25 g.
For the treatment of hepatitis B in acute form, a dose of 125 mg of drugs is prescribed in the first two days, then 125 mg every other day. The total dose per course is 2 g. If the disease is protracted, then the total dose per course is 2.5 g (that is, 20 tablets)
If a patient is diagnosed with chronic hepatitis B The total dose of Lavomax per course is 3.75-5 g. The duration of therapy can be up to 6 months. In this case, the doctor takes into account the results of laboratory tests that characterize the activity of the pathological process in the patient.
For hepatitis C in acute form, 125 mg of Lavomax is prescribed in the first 2 days, then 125 mg every other day. The total dose per course is 2.5 g. In the case of chronic hepatitis C, 250 mg is prescribed in the first two days, then 125 mg every other day. The total dose per course is 5 g. The duration of administration is determined by the doctor, taking into account laboratory parameters. Therapy can last up to 6 months.
When treating cytomegalovirus or herpetic infections, 125 mg of Lavomax is prescribed in the first 2 days, then in the same dose every other day. The total dose per course is 2.5 g. Treatment of genital herpes involves a similar dosage regimen.
Patients with non-gonococcal urethritis , respiratory and urogenital chlamydia are prescribed 125 mg in the first 2 days, then in the same dose every other day. The total dose per course is 1.25 g.
The complex treatment of pulmonary tuberculosis includes taking 250 mg of Lavomax in the first 2 days, then 125 mg every other day. The dose per course is 2.5 g.
In the complex treatment of neuroviral infections, the dosage is determined by the doctor on an individual basis. Treatment lasts 4 weeks.
Contraindications
The medication should not be taken in the following cases:
- pregnancy period;
- during breastfeeding;
- lack of sucrose and fructose, allergies to these components;
- personal intolerance to the constituent ingredients of the drug;
- children under 18 years of age.
The medicine is not recommended to be taken during puberty. In case of urgent need, no more than 125 mg can be given per day.
Lavomax's analogues
Level 4 ATC code matches:
Vekluri
Remdeform
Areplivir
Coronavirus
Avifavir
Triazavirin
Arpeflu
Yodantipyrine
Flavoside
Amizon
Altabor
Hyporamine
Anaferon for children
Anaferon
Amiksin
Arbidol
Ferrovir
Tiloron
Kagocel
Isoprinosine
Those who are interested in whether cheaper analogs of Lavomax are available for sale should be aware of the existence of drugs with similar effects, such as Amiksin and Tiloron . These drugs are produced by Russian pharmaceutical companies, so their cost is lower.
Actaviron , Tiloram and Tilaxin have a similar effect on the body .
Nosological classification (ICD-10)
- A16.2 Pulmonary tuberculosis without mention of bacteriological or histological confirmation
- A56 Other chlamydial sexually transmitted diseases
- A56.2 Chlamydial infection of the genitourinary tract, unspecified
- A56.4 Chlamydial pharyngitis
- B00 Infections caused by herpes simplex virus
- B15 Acute hepatitis A
- B16 Acute hepatitis B
- B17.1 Acute hepatitis C
- B25 Cytomegalovirus disease
- G04.8 Other encephalitis, myelitis and encephalomyelitis
- G35 Multiple sclerosis
- J06 Acute upper respiratory tract infections of multiple and unspecified localization
- J11 Influenza, virus not identified
- N34.1 Nonspecific urethritis
Lavomax price, where to buy
How much the medicine costs depends on the packaging of the drug. The price of Lavomax tablets (6 pieces) is about 500 rubles. Packaging cost is 10 pcs. – about 850 rub.
The price of Lavomax in Ukraine is about 100 hryvnia per pack of 3 pieces. Buy medicine in a package of 10 pcs. possible for about 400 hryvnia.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Lavomax tablets p.p.o.
125 mg 6 pcs. Nizhpharm OJSC 484 rub. order - Lavomax tablets p.p.o. 125 mg 10 pcs. JSC "Nizhpharm"
RUR 819 order
- Lavomax tablets p.p.o. 125 mg 3 pcs. Nizhpharm OJSC
RUB 251 order
Pharmacy Dialogue
- Lavomax tablets 125 mg No. 10Nizhpharm JSC
RUB 671 order
- Lavomax tablets 125 mg No. 6Nizhpharm JSC
RUB 506 order
- Lavomax tablets 125 mg No. 10Nizhpharm JSC
RUB 889 order
- Lavomax tablets 125 mg No. 6Nizhpharm JSC
RUB 511 order
- Lavomax tablets 125 mg No. 3Nizhpharm JSC
RUB 274 order
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Pharmacy24
- Lavomax 125 mg N3 tablets VAT "Nizhpharm", Nizhny Novgorod, Russian Federation
103 UAH. order - Lavomax 125 mg N10 tablets AT "Nizhpharm", Nizhny Novgorod, Russian Federation
390 UAH. order
PaniPharmacy
- Lavomax tablets Lavomax tablets 125 mg No. 3 Russia, Nizhpharm
112 UAH order
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Compound
Film-coated tablets | 1 table |
active substance: | |
tilorone dihydrochloride | 125 mg |
excipients: magnesium hydroxycarbonate pentahydrate - 69 mg; povidone - 4 mg; calcium stearate – 2 mg | |
shell: sucrose (sugar) - 158.2 mg; povidone - 5.56 mg; copovidone - 0.44 mg; magnesium hydroxycarbonate pentahydrate - 25.7 mg; titanium dioxide - 1.2 mg; colloidal silicon dioxide (Aerosil A380) - 1 mg; dye tropeolin O - 0.1 mg; macrogol 6000 - 6 mg; beeswax - 0.15 mg; liquid paraffin - 0.15 mg; talc - 1.5 mg |
Comparison of addiction between Ingavirin and Lavomax
Like safety, addiction also involves many factors that must be considered when evaluating a drug.
So, the totality of the values of such parameters as “o syndrome” in Ingavirin is quite similar to the similar values in Lavomax. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, Ingavirin has a fairly low “syndrome” value, just like Lavomax.
Lavomax against COVID-19 (COVID-19)
Today, most patients suffer from mild or moderate COVID-19, so they are allowed outpatient treatment with self-isolation. The prescription of medications is based on the patient’s personal characteristics (objective health, age and premorbid background).
It has been proven that interferon preparations and agents that activate its natural production can prevent the development of covid pneumonia. Currently, a number of antiviral medications are used in outpatient treatment of mild forms of COVID-19 to help avoid complications:
- Cycloferon;
- Galavit;
- Nobasite;
- Ergoferon;
- Amiksin;
- Ingavirin;
- Interferon in the form of a nasal spray (pharmacy name - Gippferon).
The prescribed Amiksin is a structural analogue of Lavomax, that is, it is made on the basis of tilorone. The drugs are interchangeable, but only with the permission of the attending physician. Self-medication can provoke unpredictable behavior of the virus in the body.
Important! There are no drugs that reduce the risk of infection with the new strain of coronavirus. Anyone can become infected. Risks can only be reduced by following the rules of prevention (distancing, wearing masks and gloves, thoroughly washing hands, treating surfaces with antiseptics).
The cost of the drug is from 235 rubles
Tips for antiviral treatment
Tip #1
You should not take antiviral drugs on your own. The doctor should choose the appropriate treatment based on your general health.
Tip #2
You must not deviate from the treatment regimen presented in the instructions. Proper administration of the medication ensures the result of therapy.
Tip #3
You cannot increase the dosage with the hope of a speedy recovery. The dose of the drug is set taking into account its pharmacodynamics and pharmacokinetics.