Description of drugs
Release form: ointment for external use. Available in metal tubes. The packaging is made of cardboard. Each one comes with instructions for use. One of the main differences is the composition. Levomekoli contains the following components:
- Levomycetin
. This is a broad-spectrum antibiotic. The substance destroys harmful microorganisms that provoke the development of a purulent, inflammatory process. Immunity to such an antibiotic occurs, but only with long-term use. - Methyluracil
. Promotes healing of injured epidermis, stops the inflammatory process, increases the body's defenses. The substance also improves cellular metabolism.
In addition to the indicated elements, Levosin contains two more elements:
- Sulfadimethoxine
. This is a substance that destroys most pathogenic microorganisms. This component also stops the inflammatory process occurring in soft tissues. - Trimekain
. Has an anesthetic effect. Thanks to this component, Levosin relieves pain.
The main active ingredients of Levomicon TFF are Levomycetin, dioxomethyltetrahydropyrimidine. Both elements stop the inflammatory process, promote wound healing, and destroy pathogenic microorganisms that provoke the formation of pus.
Levomicon-TFF
Dosage form:
Ointment for external use
Ingredients: active ingredients
: Dioxomethyltetrahydropyrimidine (methyluracil) – 4.0 g, chloramphenicol – 0.75 mg;
Excipients
: macrogol 1500 – 19.05 mg, macrogol 400 – 76.2 g.
Description
The ointment is white or white with a yellowish tint.
Pharmacotherapeutic group
Combined antimicrobial agent.
ATX code: D06С
Pharmacological properties
A combined preparation for external use that has anti-inflammatory (dehydrating) and antimicrobial effects. Chloramphenicol disrupts the process of protein synthesis in the microbial cell and is a bacteriostatic antibiotic.
Active against gram-positive and gram-negative microorganisms (staphylococci, Pseudomonas aeruginosa and Escherichia coli, etc.). Easily penetrates deep into tissues without damaging biological membranes. In the presence of pus and necrotic masses, the antibacterial effect remains. Dioxomethyltetrahydropyrimidine, normalizing nucleic acid metabolism, stimulates regeneration processes in wounds, growth and granulation maturation of tissue, epithelization, and has an anti-inflammatory (dehydrating) effect.
Indications for use
Purulent wounds (including those infected with mixed microflora) in the first (purulent-necrotic) phase of the wound process. If necessary, please consult your doctor before using the medicine.
Contraindications
Hypersensitivity to the components of the drug, children under one year of age (in newborns, the biotransformation of chloramphenicol occurs more slowly than in adults).
Carefully
Pregnancy, lactation period.
Use during pregnancy and breastfeeding
Use during pregnancy is possible only if the benefit to the mother outweighs the risk to the fetus.
During lactation, you should either stop using the drug or breastfeeding.
Directions for use and doses
Externally. The drug is impregnated with sterile gauze pads, which are used to loosely clean the wound. It is possible to administer the drug into purulent cavities through a catheter (drainage tube) using a syringe. In this case, the ointment is preheated to 35-36 °C. Dressings are performed daily, once a day, until the wound is completely cleansed of purulent-necrotic masses. For large wound surfaces, the daily dose of ointment in terms of chloramphenicol should not exceed 3 g. The duration of treatment depends on the severity and course of the disease. If there is no improvement after treatment or new symptoms appear, you should consult your doctor. Use the drug only according to the method of use and in the doses indicated in the instructions. If necessary, please consult your doctor before using the medicine.
Side effect
Allergic reactions (skin rashes). In this case, you should stop using the drug and consult a doctor. If any of the side effects indicated in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.
Overdose
No cases of overdose have been reported.
Drug interactions
Cases of interaction or incompatibility with other drugs have not been described.
special instructions
When applied to large areas of skin and long-term courses of treatment, it is necessary to conduct a clinical blood test.
Impact on the ability to drive vehicles and machinery
Does not affect the ability to drive vehicles and other mechanisms.
Release form
Ointment for external use.
20, 25, 30, 40, 50, 60, 70, 80, 100 g in orange glass jars with a triangular rim with a pull-on lid with a sealing element.
20, 25, 30, 40, 50, 60, 70, 80, 100 g in polymer jars complete with lids and polyethylene terephthalate jars with closures.
20, 25, 30, 40, 50, 60, 70, 80, 100 g in aluminum tubes, coated with BF-2 varnish, with caps made of high-density polyethylene or in polymer tubes with polyethylene screw caps.
Each jar and tube, along with instructions for use, is placed in a cardboard pack.
Storage conditions
At a temperature not exceeding 20 °C.
Keep out of the reach of children.
Best before date
3 years 6 months. Do not use after the expiration date stated on the label.
Vacation conditions
Available without a prescription.
Indications and contraindications
Indications for use:
- damage to the epidermis - cuts, scratches, other similar injuries;
- wounds in which a purulent process occurs;
- cuts, scratches, abrasions, and other injuries that do not heal for a long time;
- thermal, sunburn;
- boils and other purulent rashes;
- necrosis of soft tissues, which occurs due to constant exposure to a supine position, which entails disturbances in local blood circulation and nerve trophism;
- purulent inflammatory process on the fingers;
- hemorrhoids, anal fissures;
- for healing postoperative sutures.
There is also no difference in contraindications. It is not recommended to use if you have subjective intolerance to any component. Use with caution during pregnancy and lactation. The fact is that any hormonal ointment is harmful for a baby, as well as any product that contains antibiotics, since such drugs can negatively affect the health or development of the child. During pregnancy and breastfeeding, medications should be used only as prescribed by a doctor. However, experts most often prescribe analogues without antibiotics on a non-hormonal basis - these are Bepanten or Vishnevsky ointment.
Contraindications
Hypersensitivity to the components of the drug, children under 1 year of age (in newborns, the biotransformation of chloramphenicol occurs more slowly than in adults).
With caution: pregnancy, lactation period.
Use during pregnancy and breastfeeding
Use during pregnancy is possible only if the benefit to the mother outweighs the risk to the fetus.
During lactation, you should either stop using the drug or breastfeeding.
Instructions for use
Instructions for using medications are no different. They are used in two ways:
- The medicine is used to treat the injured epidermis and a sterile gauze pad. The bandage is fixed on the problem area of the skin. The napkin is changed every 12 hours. The procedure is carried out until the injury heals.
- Injected into an open wound with a syringe through a catheter. The medication is pre-warmed to body temperature. The duration of therapy is until the wound heals.
A positive result is achieved 2-3 days after the start of therapy.
When granulation appears, treatment is stopped. After this, the wound heals itself. To ensure that there is no scar left on the skin, other drugs without antibiotics are used. The dosage and duration of treatment is determined by a specialist.
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Directions for use and doses
Externally.
The drug is impregnated with sterile gauze pads, which are used to loosely clean the wound. It is possible to administer the drug into purulent cavities through a catheter (drainage tube) using a syringe. In this case, the ointment is preheated to 35-36 °C. Dressings are performed daily, once a day, until the wound is completely cleansed of purulent-necrotic masses.
For large wound surfaces, the daily dose of ointment in terms of chloramphenicol should not exceed 3 g.
The duration of treatment depends on the severity and course of the disease.
If there is no improvement after treatment or new symptoms appear, you should consult your doctor.
Use the drug only according to the method of use and in the doses indicated in the instructions.
If necessary, please consult your doctor before using the medicine.
Side effects
Such medications rarely cause side effects. Usually their appearance is associated with subjective intolerance to any component present in the medicine. After applying the product, atypical reactions of the body appear:
- rashes;
- itching;
- burning;
- swelling of soft tissues;
- redness.
If side effects occur, stop therapy and consult a doctor. The specialist helps you get rid of the problem and prescribes other medications.
Comparison of drugs
Despite the fact that the drugs have similar properties, it cannot be said that they are the same products. They differ primarily in composition.
Since Levosin contains an additional component, it begins to act faster than others. Otherwise, the drugs are similar in both indications for use, contraindications and even side effects.
Which remedy is better?
It is impossible to say for sure which remedy is better. Much depends on the body's reaction. The products have proven their effectiveness, however, Levosin is in great demand among users. This is due to the following factors:
- a more reasonable price, which is about 50 rubles;
- the presence of an additional component in the composition;
- higher content of main active ingredients;
- additional anesthetic properties.
However, this medicine more often than others provokes an atypical reaction of the body due to the high concentration of the component and the double antibiotic. Despite this, it is best to use Levosin.
Analogues of funds
On the pharmacological market, not only Levosin, Levomekol and Levomicon TFF have anti-inflammatory and antimicrobial properties. You can purchase analogues that are also used to heal injured epidermis.
Drug name | Active substance | Manufacturer | Approximate cost, rub. |
Baneocin | Bacitracin, neomycin | Pharmaceuticals Fabrik Montavit GmbH, Austria | 160 |
Betadine | Povidone-iodine | CJSC Pharmaceutical Plant EGIS, Hungary | 150 |
Heparin ointment | Sodium heparin, benzocaine, benzyl nicotinate | JSC Nizhpharm, Russia | 40 |
Ichthyolka | Ichthammol | Russian companies | 60 |
Solcoseryl | Deproteinized hemoderivative | MEDA PHARMACEUTICALS SWITZERLAND GmbH, Switzerland | 190 |
Syntomycin ointment or Syntomycin | D, L-chloramphenicol | Federal State Unitary Enterprise "Murom Instrument-Making Plant", Russia | 50 |
Stellanin | Diethylbenzimidazolium triiodite | Pharmpreparat, Russia | 390 |
Streptocide | Sulfanilamide | Lumi LLC, Russia | 15 |
Tetracycline ointment | Tetracycline | Russian companies | 40 |
Oflomelid | Ofloxacin, methyluracil, lidocaine hydrochloride | Sintez AKO OJSC, Russia | 95 |
Panthenol | Dexpanthenol | Russian and foreign companies | 100 |
Levomethyl | Dioxomethyltetrahydropyrimidine, chloramphenicol | CJSC "Green Dubrava", Russia | 28 |
When choosing from the drugs Levosin, Levomekol and Levomikon TFF, it is recommended to use the first remedy. This is due to its greater effectiveness and analgesic properties. The product quickly relieves the problem and rarely causes side effects.
pharmachologic effect
A combined preparation for external use that has anti-inflammatory (dehydrating) and antimicrobial effects. Chloramphenicol disrupts the process of protein synthesis in the microbial cell and is a bacteriostatic antibiotic.
Active against gram-positive and gram-negative microorganisms (staphylococci, Pseudomonas aeruginosa and Escherichia coli, etc.). Easily penetrates deep into tissues without damaging biological membranes. In the presence of pus and necrotic masses, the antibacterial effect remains. Dioxomethyltetrahydropyrimidine, normalizing nucleic acid metabolism, stimulates regeneration processes in wounds, growth and granulation maturation of tissue, epithelization, and has an anti-inflammatory (dehydrating) effect.