pharmachologic effect
Stellanin-PEG ointment should be used for “weeping” wounds with purulent contents (1,3-Diethylbenzimidazolium triiodide provides antimicrobial, anti-inflammatory and regenerative effects necessary for rapid and successful wound healing)
The mechanism of pharmacological activity of the drug is the antibacterial effect of 1.3-diethylbenzimidazolium. Active iodine, which is part of 1.3-diethylbenzimidazolium triiodide, inactivates bacterial wall proteins and bacterial enzyme proteins, thereby exerting a bactericidal effect on microorganisms. The pronounced antimicrobial effect of the drug prevents wound infection.
Along with antibacterial and anti-inflammatory effects, the ointment has a high osmotic potential, which is especially important in the treatment of purulent wounds, because promotes the evacuation of purulent discharge from the wound defect.
The most significant feature of the use of Stelanin preparations is their ability to significantly reduce the healing time of a wound and prevent the formation of scars in its place.
Stellanin-Peg ointment for external use 3% 20g
Compound
Active substance: 1,3-Diethylbenzimidazolium triiodide - 3 g.
Excipients: povidone K17 (low molecular weight polyvinylpyrrolidone) - 2 g, dimethyl sulfoxide (dimexide) - 5 g, macrogol 1500 (polyethylene oxide 1500, polyethylene glycol 1500) - 25 g, macrogol 400 ( polyethylene oxide 400, polyethylene glycol 400) - 65 g.
Pharmacokinetics
Systemic absorption of the active substance is absent even with damaged skin, however, therapeutic concentrations of the drug are present in the wound.
Indications for use
- Treatment of acute purulent processes (wounds) of the skin and soft tissues (boils, carbuncles, hydroadenitis, phlegmon, abscesses);
- additional treatment of purulent complications of postoperative wounds (after excision, coagulation, episiotomy, for the treatment of skin cracks, wounds and sutures);
- thermal lesions of the skin and soft tissues of I-III degrees, complicated by an infectious process;
- trophic ulcers, bedsores complicated by an infectious process;
- abrasions, cuts, scratches, cracks, scratches.
Contraindications
- Hypersensitivity to the components of the drug;
- thyrotoxicosis;
- thyroid adenoma;
- severe renal failure;
- simultaneous therapy with radioactive iodine;
- children under 18 years of age;
- I trimester of pregnancy.
With caution: chronic renal failure, II and III trimesters of pregnancy, lactation period.
Directions for use and doses
The ointment is applied in a thin layer of about 1.5-2 mm directly to the wound surface, after which a sterile gauze bandage is applied or the drug is applied to the dressing material and then to the wound. The ointment layer should exceed the circumference of the wound by at least 5 mm. Tampons soaked in ointment are loosely filled into the cavities of purulent wounds after surgical treatment, and gauze turundas with the drug are injected into the fistulous tracts. If the wound is localized in a place that is inconvenient for bandaging, it is permissible to use an adhesive bandage or adhesive bandage.
The dressings are changed 1-2 times a day.
The daily dose should not exceed 10 g. The duration of treatment is on average 5 - 15 days.
For minor skin damage (abrasions, cuts, scratches, cracks, scratches), the drug is applied in a thin layer to the affected surface 2 times a day.
Storage conditions
The drug should be stored in a dry place, protected from light, at a temperature of 0-25 ° C. Keep out of the reach of children.
Best before date
2 years. Do not use after the expiration date stated on the packaging.
special instructions
Avoid getting the ointment in your eyes. If the drug gets into your eyes, rinse with warm water.
Description
Tissue regeneration stimulator.
Pharmacodynamics
The mechanism of pharmacological activity of the drug is the antibacterial effect of 1.3-diethylbenzimidazolium. Active iodine, which is part of 1.3-diethylbenzimidazolium triiodide, inactivates bacterial wall proteins and bacterial enzyme proteins, thereby exerting a bactericidal effect on microorganisms. The pronounced antimicrobial effect of the drug prevents wound infection.
Along with antibacterial and anti-inflammatory effects, the ointment has a high osmotic potential, which is especially important in the treatment of purulent wounds, because promotes the evacuation of purulent discharge from the wound defect.
Side effects
In rare cases, allergic skin reactions (itching, skin hyperemia) are possible, and if they occur, you should stop using the drug.
Use during pregnancy and breastfeeding
It is forbidden to take the drug in the first trimester of pregnancy.
Take with caution in the 2nd and 3rd trimesters of pregnancy and lactation.
Interaction
The drug should not be used in combination with other antiseptics containing mercury, oxidizing agents, alkalis and cationic surfactants. An alkaline or acidic environment, the presence of fat, pus, and blood weaken the antiseptic activity.
Overdose
Cases of overdose have not been described. If the drug is accidentally taken orally, nausea and vomiting may occur. It is necessary to rinse the stomach and consult a doctor; if necessary, carry out symptomatic treatment.
Indications for use
- treatment of acute purulent processes (wounds) of the skin and soft tissues (boils, carbuncles, hydroadenitis, phlegmon, abscesses);
- additional treatment of purulent complications of postoperative wounds (after excision, coagulation, episiotomy, for the treatment of cracks in the skin, wounds and sutures);
— thermal damage to the skin and soft tissues of I-III degrees, complicated by an infectious process;
- trophic ulcers, bedsores, complicated by an infectious process.
—- abrasions, cuts, scratches, cracks, scratches.
Directions for use and doses
The ointment is applied in a thin layer of about 1.5-2 mm directly to the wound surface, after which a sterile gauze bandage is applied or the drug is applied to the dressing material and then to the wound. The ointment layer should exceed the circumference of the wound by at least 5 mm. Tampons soaked in ointment are loosely filled into the cavities of purulent wounds after surgical treatment, and gauze turundas with the drug are injected into the fistulous tracts. If the wound is localized in a place that is inconvenient for bandaging, it is permissible to use an adhesive bandage or adhesive bandage.
Dressings are changed 1-2 times per
The daily dose should not exceed 10 g. The duration of treatment is on average 5 - 15 days.
For minor skin damage (abrasions, cuts, scratches, cracks, scratches), the drug is applied in a thin layer to the affected surface 2 times a day.
Stellanin-PEG ointment 3%
Features of the use of the drug Stellanin®-PEG In the first phase of the wound process (in purulent wounds with a sluggish ongoing chronic inflammatory process), the drug "Stellanin®-PEG ointment for external use 3%" has a pronounced antibacterial effect on infectious agents and, having high osmotic activity, ensures intensive outflow of exudate from the depths of the wound, rejection and melting of necrotic tissue and evacuation of wound contents. The 1,3-Diethylbenzimidazolium triiodide used in the preparation “Stellanin®-PEG ointment for external use 3%” provides antimicrobial, anti-inflammatory and regenerative effects necessary for rapid and successful wound healing.
Instructions for medical use of the drug Stellanin®-PEG
Trade name: Stellanin®-PEG
Chemical name: 1,3-diethylbenzimidazolium triiodide
Dosage form: Ointment for external use
Composition of 100 g of ointment: Active substance: 1,3-diethylbenzimidazolium triiodide - 3.0 g Excipients: povidone (low molecular weight polyvinylpyrrolidone), dimexide, polyethylene oxide 1500 (polyethylene glycol 1500), polyethylene oxide 400 (polyethylene glycol 400).
Description: The ointment is dark brown in color with a weak characteristic odor.
Pharmacotherapeutic group Antiseptic
ATX code: D08AG
Pharmacological properties: Pharmacodynamics The mechanism of pharmacological activity of the drug is the antibacterial effect of 1,3-diethylbenzimidazolium. Active iodine, which is part of 1,3-diethylbenzimidazolium triiodide, inactivates bacterial wall proteins and bacterial enzyme proteins, thereby exerting a bactericidal effect on microorganisms. The pronounced antimicrobial effect of the drug prevents wound infection. Along with antibacterial and anti-inflammatory effects, the ointment has a high osmotic potential, which is especially important in the treatment of purulent wounds, because promotes the evacuation of purulent discharge from the wound defect. Pharmacokinetics: Systemic absorption of the active substance is absent even with damaged skin, however, therapeutic concentrations of the drug are present in the wound.
Indications for use:
- Treatment of acute purulent processes (wounds) of the skin and soft tissues (boils, carbuncles, hydroadenitis, phlegmon, abscesses).
- Additional treatment of purulent complications of postoperative wounds (after excision, coagulation, episiotomy, for the treatment of skin cracks, wounds and sutures).
- Thermal lesions of the skin and soft tissues of I-III degrees, complicated by an infectious process.
- Trophic ulcers, bedsores, complicated by an infectious process.
- Abrasions, cuts, scratches, cracks, scratches.
Contraindications: Hypersensitivity to the components of the drug, thyrotoxicosis, thyroid adenoma, severe renal failure, simultaneous therapy with radioactive iodine, children under 18 years of age, first trimester of pregnancy.
With caution: Chronic renal failure, II and III trimesters of pregnancy, lactation period.
Method of administration and dosage: The ointment is applied in a thin layer of about 1.5-2 mm directly to the wound surface, after which a sterile gauze bandage is applied or the drug is applied to the dressing material and then to the wound. The ointment layer should exceed the circumference of the wound by at least 5 mm. Tampons soaked in ointment are loosely filled into the cavities of purulent wounds after their surgical treatment, and gauze turundas with the drug are inserted into the fistula tracts. Dressings are changed 1-2 times a day when treating wounds and trophic ulcers. If the wound is localized in a place that is inconvenient for bandaging, it is permissible to use an adhesive bandage or adhesive bandage. The daily dose should not exceed 10 g. The duration of treatment is on average 5 - 15 days. For minor skin damage (abrasions, cuts, scratches, cracks, scratches), the drug is applied in a thin layer to the affected surface twice a day.
Side effects: In rare cases, allergic skin reactions (itching, skin flushing) are possible, if they occur, you should stop using the drug.
Overdose : Cases of overdose have not been described. If the drug is accidentally taken orally, nausea and vomiting may occur. It is necessary to rinse the stomach and consult a doctor; if necessary, carry out symptomatic treatment.
Interaction with other drugs: The drug should not be used in combination with other antiseptics containing mercury, oxidizing agents, alkalis and cationic surfactants. An alkaline or acidic environment, the presence of fat, pus, and blood weaken the antiseptic activity.
Special instructions: Avoid getting the ointment in the eyes. If the drug gets into your eyes, rinse with warm water.
Release form: Ointment for external use 3%. 20 g in aluminum tubes along with instructions for use in cardboard packs.
Storage conditions: In a dry place, protected from light, at a temperature of 0-25 ° C. Keep out of the reach of children.
Shelf life: 2 years. Do not use after the expiration date stated on the packaging.
Dispensing conditions: Without a prescription.
Manufacturer/Enterprise accepting quality claims: Pharmpreparat LLC 346780 Russian Federation, Rostov region, Azov, st. Kalinina, 2 Tel. (86342) 5-26-39
