Hyaluronidase - how to eliminate the consequences of complications after using hyaluronic acid

Physiotherapeutic procedures are widely used as an additional method to the main treatment, as well as during rehabilitation. This group of methods includes electrophoresis with lidase.

This technique is used in the rehabilitation clinic of the Yusupov Hospital in the treatment of various diseases. The affordable cost of the procedure is combined with the professionalism of specialists and the friendly attitude of the staff, which makes a stay at the Yusupov Hospital not only comfortable, but also beneficial for the body.

What are adhesions in gynecology

Adhesive disease of the pelvic organs in women is a complication after which fibrinous connective tissue grows between the pelvic and abdominal organs.
In this way, the body tries to protect the source of inflammation - due to excess tissue, the fallopian tubes, uterus, ovary and intestinal loops stick together, pull tightly together, which disrupts their functions. Adhesive processes can be of several types, depending on the “neglect”:

  1. Formation of single thin adhesions (synechia).
  2. Synechiae become denser, covering up to 50% of the surface of the ovary.
  3. The adhesions are dense and numerous, changing the position of organs or causing their deformation.

Adhesions cause pain and disturbances in the functioning of the pelvic organs. They appear after gynecological diseases or operations and can lead to serious complications: ectopic pregnancy, infertility, frequent inflammation and more.

To prevent the occurrence of adhesions, avoid complications and prescribe competent treatment, make an appointment with the doctors of the Doctor A clinic. We employ gynecologists of the first and highest qualification categories

How quickly does hyaluronidase work?

The effect of hyaluronidase is immediate, but often causes swelling, so most often patients see the effect of complete dissolution of hyaluronidase only after 2-3 days.

  • If it is necessary to dissolve only part of the hyaluronic acid, small doses of the enzyme must be administered every 10-14 days.
  • If we are dealing with a serious complication and want to dissolve all the acid at once, large doses of the enzyme should be used.


Effect of hyaluronidase

What causes adhesions to form in the pelvis

Inflammation of the pelvic organs. The disease is diagnosed in women who have suffered acute inflammation or suffer from chronic:

  • colpitis;
  • endometritis;
  • andexite;
  • parametritis and other diseases.

Operations. Adhesive disease appears in 16% of those operated for the first time and in 96% of women after the third operation. The percentage is high for laparotomy operations:

  • appendectomy;
  • C-section;
  • removal of appendages;
  • hysterectomy;
  • supravaginal amputation.

Pelvic hemorrhages. The trigger is ovarian apoplexy, bleeding due to a ruptured tube during an ectopic pregnancy.

Endometriosis. The formation of fibrinous ties is provoked by endometrioid growths, which spread to the organs and peritoneum of the pelvis.

Pelvic injuries. Open and closed damage after accidents, falls from a height received at work are one of the reasons for the appearance of adhesions.

Predisposing factors. The occurrence and development of the disease is influenced by:

  • invasive gynecological interventions;
  • promiscuous sex life;
  • late visit to the clinic.

Indications for procedures

Electrophoresis is prescribed to all patients diagnosed with a hernia who experience severe pain - an inevitable companion to this disease. Other indications depend on the type of protrusion.

Each type of intervertebral hernia has serious complications, so you should not delay treatment.
See how easy it is to get rid of a hernia in 10 sessions

Indications for electrophoresis for cervical hernia

For herniated intervertebral discs in the cervical spine, electrophoresis is prescribed for:

  • dizziness and migraines;
  • surges in blood pressure;
  • weakness in the upper limbs;
  • loss of sensitivity in the limbs;
  • limitation of movement, muscle weakness.

Read more about cervical hernia in this article.

Indications for electrophoresis for thoracic hernia

For a thoracic hernia, electrophoresis is indicated for anyone who has:

  • numbness, tingling in the upper extremities;
  • limited mobility due to muscle hypertonicity.

Read more about the symptoms and treatment of thoracic intervertebral hernia here.

Indications for electrophoresis for lumbar hernia

For a lumbar hernia, electrophoresis is prescribed if the following symptoms are present:

  • tingling sensation, numbness of the lower extremities;
  • problems with urination;
  • the feeling that “your legs won’t obey you.”

Read about other symptoms in the article “Intervertebral hernia of the lumbar spine.”

Adhesions in gynecology: symptoms

The adhesive process can be both acute and chronic, or have a periodic nature (with periodic exacerbation of symptoms). Often, women do not notice any symptoms of adhesions in the pelvis, and the disease is discovered only when examining the possible causes of infertility.

Signs of adhesions in the pelvic cavity:

  • Painful sensations in the lower abdomen, lower back, above the pubis or in the sacral area;
  • Discomfort during physical activity, before menstruation, after stressful situations;
  • Pain during sexual intercourse or urination;
  • Intestinal disorders: diarrhea, constipation, flatulence;
  • Periodic attacks of nausea and vomiting.

Symptoms may worsen when consuming foods that increase gas formation.

Lidase electrophoresis: mechanism of action

Specialists working in the field of aesthetic medicine are faced with solving various problems, the most labor-intensive of which is working with scars. Electrophoresis with lidase is used to treat keloid and hypertrophic scars. This procedure is also used to treat gynecological diseases.

The mechanism of action of electrophoresis is based on the effect on the affected tissues and organs of a low-level direct current, as a result of which metabolic processes in the body are accelerated and rapid cell regeneration occurs. Lidase is an enzyme that increases tissue permeability, improves blood circulation and reduces swelling. Electrophoresis allows the active ingredient lidase to be delivered through the skin. This method does not involve damaging the integrity of the skin, but it allows you to get a positive result.

Many women who are indicated for this procedure ask specialists whether electrophoresis with lidase is safe and effective during menstruation. During menstruation, this procedure can be used, but it is important that the area of ​​influence be clearly localized.

When performing electrophoresis with lidase, specialists at the Yusupov Hospital Rehabilitation Center use high-quality European equipment, which is safe and free of discomfort. An important advantage of visiting the Yusupov Hospital to undergo a course of procedures is the affordable cost of services, which is combined with the professionalism of doctors and the respectful attitude of the staff.

Diagnosis of the disease

Diagnosis of adhesions in the pelvis is carried out using various studies:

  • Diagnostic laparoscopy. This method can most accurately see adhesions and assess the severity of the process. Diagnosis is carried out under local (or general) anesthesia; a small incision is made through which a camera is inserted.
  • Ultrasound of the pelvic organs;
  • Hysterosalpingography (performed using X-rays or ultrasound and contrast agents);
  • MRI of the pelvic organs.

The necessary examination (or set of examinations) will be prescribed to you by your attending physician.

What medications are used for electrophoresis for hernia

Karipazim


Carazipam for electrophoresis

It is a solution for external use, which contains papain, a natural plant substance. The main effect of the drug is the breakdown of necrotic elements and the dilution of blood clots, viscous secretions and other protein compounds. Electrophoresis has a beneficial effect on cartilage tissue, stimulating its regeneration, and enhances the restoration of intervertebral disc tissue.

For external use only. Side effects include allergic reactions. Contraindications: pregnancy, breastfeeding and hypersensitivity to the main component. Does not have a systemic effect on the body.

No cases of drug overdose have been identified. There are no important clinically significant interactions with other drugs. Produced in Georgia and Russia. The price for one ampoule, on average, is from 60 rubles.

The course of treatment must be at least 14 procedures.

Karipain Plus


Karipain Plus for electrophoresis

The drug contains papain, bromelain (an enzyme isolated from pineapple pulp), lysozyme (an antibacterial agent), collagenase (an enzyme that breaks down collagen) and excipients (sodium chloride and lactose monohydrate). It relieves local inflammatory processes and reduces joint pain. Stimulates microcirculatory processes and restores skin elasticity. With the help of galvanization, it penetrates deep into the tissue, stimulates natural reconstructive processes, and softens the hernia. This helps relieve inflammation and reduce pain.

Among the contraindications:

  • pregnancy period;
  • acute inflammatory processes;
  • tissue necrosis;
  • disintegration of the intervertebral disc;
  • allergic reactions.

No cases of overdose have been identified. There are no important clinically significant interactions with other drugs. Produced in Georgia and Russia. The price for one ampoule, on average, is from 210 rubles.

The number of sessions is individual, on average 10-20 sessions.

Novocaine


Novocaine for electrophoresis

The main active ingredient of the drug is procaine hydrochloride 5 mg or 20 mg. Auxiliary ingredients: sodium chloride, water for injection. The drug is available in the form of an injection solution. Has a local anesthetic effect. Therefore, it is prescribed mainly to patients with pronounced pain syndrome due to a hernia.

Contraindications include hypersensitivity to the main active ingredient, progressive cardiovascular disorders, and pregnancy.

Side effects include:

  • headache;
  • drowsiness, weakness;
  • blood pressure surges;
  • tachycardia;
  • nervous excitement.

Novocaine enhances the effect of sedatives, anesthetics and muscle relaxants. Therefore, it must be used for electrophoresis strictly as prescribed by the attending physician.

They mainly use a drug of Russian origin. The price for 10 ampoules of 0.5% 10 ml starts from 50 rubles. The duration of the course and dosage are regulated by the doctor.

Eufillin


Eufillin for electrophoresis

The active ingredient of the drug is aminophylline. The effect of the drug leads to a decrease in muscle contractile activity. Eufillin is mainly used in pulmonology. In the treatment of hernias, it is used to dilate blood vessels, which improves blood flow in the lesion and stimulates venous outflow. Due to this, pain is reduced and swelling in the area of ​​inflammation is resolved. Thanks to galvanization, the drug has a targeted effect without having a systemic effect.

Local application reduces the occurrence of side effects. A slight drop in blood pressure, dizziness, and tachycardia may occur. Contraindications: allergic reactions, convulsions, severe liver or kidney failure.

Eufillin increases the effect of glucocorticoids, drugs that excite the central nervous system. Reduces the activity of lithium salts. The country of manufacture of the drug is Russia. A box of 10 ampoules will cost 40-60 rubles.

Trypsin


Trypsion for electrophoresis

Trypsin is an enzyme of the hydrolase class that breaks down peptides and proteins. Therefore, its pharmacological effect is regenerative and anti-inflammatory. The main function is the disposal of half-life products.

Contraindications: tumor processes, pregnancy, allergic reactions. Side effects include: tachycardia, allergies.

There are no important clinically significant interactions with other drugs. Trypsin is produced in Russia. The price for trypsin 10 ampoules of 10 mg each starts at an average of 500 rubles.

The duration of the course and dosage are prescribed by the attending physician.

We use non-surgical hernia treatment techniques
Read more about our unique technique

How to treat adhesions in the pelvis

What to do if adhesions are found in the pelvis? Depending on the severity of the adhesive process, the doctor will select the appropriate treatment for you.

To treat single thin adhesions in the pelvis in women, drug therapy is used. What is usually prescribed:

  • Antibiotics and antimicrobial agents (to relieve inflammation);
  • Non-steroidal anti-inflammatory drugs (as a pain reliever);
  • Fibrinolytic agents (for resorption of adhesions);
  • Vitamins and immune system regulators (to restore immune balance);
  • Hormonal drugs (in cases where adhesions are caused by endometriosis).

Additionally, physiotherapy, balneotherapy and mud therapy may be prescribed as auxiliary measures.

In more severe forms of adhesive disease, a surgical method is used to treat adhesions in the pelvis, i.e. their dissection. The most gentle surgical procedure is manipulative laparoscopy. To prevent re-formation of adhesions, hyaluronic acid is injected into the surgical area.

What complications after the injection of hyaluronic acid will hyaluronidase help with?

If you contact an experienced cosmetologist-dermatologist in a timely manner, he will be able to help in any situation, except blindness and skin necrosis. Of course, the introduction of hyaluronidase will not give anything if it was not hyaluronic acid that was used, but some other drug of unknown origin. Hyaluronidase acts on any cross-linked hyaluronic acid that is approved for injection in the European Union.


Hyaluronidase

Is it possible to get pregnant during adhesions?

Adhesions disrupt the proper functionality of the reproductive organs, which greatly reduces the chance of getting pregnant. There is a chance of pregnancy and its successful gestation, especially in cases where the adhesive process affected only one tube. But the likelihood of conception decreases, and the risk of ectopic pregnancy and miscarriage also increases.

In this case, IVF may help. The fallopian tubes are not involved in such fertilization, and a 3-5-day-old embryo is immediately implanted into the uterine cavity.

Carrying out at home

Before starting self-medication, it is imperative to consult a doctor. He will prescribe a course of treatment and the necessary medications. The wrong dosage or medication may cause more harm than good. Also, if you are not sure that you will do everything correctly during the first procedure, it is better to have a medical professional nearby and show everything.

For galvanization, many doctors advise purchasing the Potok-1 or Elfor device. They have simple controls, different modes with different current strengths. The price of the device varies from 5,000 to 12,000 rubles. You will also need pads made of gauze or fabric.

Scheme:

  1. Prepare a working solution. Attention, you can only use freshly prepared mixture.
  2. The electrodes are fixed exclusively on napkins moistened with a solution, otherwise a chemical burn is possible.
  3. Remove clothing from the required area of ​​the body to apply electrodes.
  4. Secure the electrodes and place bags of salt, sand, etc. on top of them for a tighter fit.
  5. At the end of the procedure, gradually reduce the current supply, turn off the device and only then remove the electrodes.
  6. Stay calm for 10-15 minutes.

If all prescribed doctor's recommendations are followed, electrophoresis performed at home is in no way inferior in effectiveness. However, it is still worth visiting a doctor in the middle and at the end of the course so that he can determine how much the treatment has helped and whether it is worth adjusting. If pain occurs, the procedure should be stopped immediately and consult a specialist.

Prevention of adhesions

For the prevention and treatment of adhesions, enzyme preparations based on hyaluronidase are used. Perhaps the most popular drug for the treatment of adhesions in gynecology is Longidaza suppositories.

Prevention is mostly aimed at preventing relapses of the disease or before an upcoming operation (since adhesions often appear after them).

Remember that the best prevention is regular visits to the doctor and timely diagnosis. Don’t delay until later and sign up for a pelvic ultrasound or a consultation with a gynecologist.

If you feel acute pain in the abdominal cavity or pelvic organs, do not delay visiting a doctor - prevent the development of the disease. Doctors at the Doctor A clinic will conduct an expert examination and prescribe competent treatment. Call or make an appointment online.

Electrophoresis with lidase: contraindications

Before performing electrophoresis with lidase, specialists from the Yusupov Hospital Rehabilitation Center carry out a comprehensive diagnosis aimed at identifying possible contraindications.

The main contraindications for electrophoresis with lidase:

  • diseases and damage to the skin;
  • malignant formations;
  • increased body temperature;
  • allergic reaction to lidase;
  • diseases of the heart and blood vessels;
  • bronchial asthma;
  • diseases of the endocrine system;
  • pulmonary tuberculosis;
  • high sensitivity to electrical discharges.

During pregnancy and lactation, the use of this procedure should also be limited. Lidase for electrophoresis, the price of which is affordable, does not cause unpleasant sensations, nor does exposure to electric current, but during this period the woman is the most sensitive and vulnerable.

The Yusupov Hospital employs experienced physiotherapists who regularly improve their skills, so when contacting the rehabilitation center, patients can be confident that the services provided meet international quality standards.

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