Basic properties of Bonisan:
- Relief of symptoms of menopause in women, such as: hot flashes, sleep disturbances, increased night sweats, headaches, mood swings, irritability
- Prevention of osteoporosis (the process of “washing out” calcium from bone tissue)
- Reducing the risk of developing diseases of the cardiovascular system
- Improved skin appearance
- Slowing down the aging process of the body
Isoflavones are natural substances (phytoestrogens), whose molecules are similar in structure and action to female sex hormones (estrogens). The activity of such substances is significantly lower than that of their synthetic analogues.
Isoflavones, depending on the concentration of sex hormones in the bloodstream, exhibit dual activity: both estrogenic and antiestrogenic. If there is a deficiency of biologically active substances, they replace the existing deficiency, however, due to their mild natural action, they do not have the side effects that are characteristic of synthetic drugs.
Action
- Slows down the aging of the body;
- Improves skin condition;
- Relieves the characteristic symptoms of menopause (hot flashes, insomnia, night sweats, headaches and frequent mood swings);
- Prevents the occurrence of osteoporosis in women during menopause;
- Reduces the risk of cardiovascular diseases.
Recommended for maintaining the required level of hormones in a woman’s body. Does not cause side effects.
Isoflavones are natural phytoestrogens, the molecules of which are very similar, but not identical, to the molecules of female hormones - estrogens. As you know, hormone replacement therapy is often prescribed in connection with various diseases - for both men and women. However, the activity of natural isoflavones, in contrast to synthetic hormones, is tens of thousands of times lower. Isoflavones (daidzein, glycitein, genistein) have a hormone-like effect. They act selectively, exhibiting both estrogenic and antiestrogenic activity, depending on the amount of estrogens contained in the blood. Soy isoflavones exhibit effects similar to the action of the female body’s own estrogens, i.e. devoid of the side effects that synthetic estrogens have. Studies conducted in Japan, where residents consume isoflavones in large quantities of soy foods, have shown that they help reduce the risk of many human diseases. As you know, residents of Asian countries rarely suffer from excess weight, cardiovascular diseases, and symptoms associated with menopause in women. In Russia, due to the low consumption of legumes rich in isoflavones, it is necessary to compensate for their deficiency with the help of dietary supplements.
Menopause During menopause, estrogen secretion in women decreases significantly. Moreover, during menopause, the skin usually becomes thinner, loses its elasticity, and wrinkles appear. This occurs due to the loss of collagen and elastin, the main proteins that keep skin in good condition. Isoflavones help preserve collagen content, its elastic properties, reduce the depth of wrinkles and maintain skin hydration. As a result, the skin appears more radiant and smooth.
Osteoporosis Osteoporosis is a disease of the skeletal bones in which the structure of the bones changes and their strength decreases. In osteoporosis, bone fractures occur with minimal or even normal physical activity. The most susceptible bones to fracture are the femur at the femoral neck, the spine and the wrist. This is a very dangerous and worldwide problem, especially for women. 15 years after menopause, the incidence of fractures in women increases 10 times. Bonisan isoflavones in the diet significantly reduces the risk of osteoporosis. In addition, they help maintain calcium in the body. Recent research in this area has found that daily consumption of 1 capsule of the Bonisan increases skeletal bone density in the lumbar spine in postmenopausal women.
Cardiovascular diseases occupy a leading place in mortality cases. People with high blood cholesterol have an increased risk of heart disease. Recent studies have shown that the use of isoflavones reduces cholesterol levels in human blood.
Cancer Recently, tremendous interest has been generated by the apparent role of soy products in reducing the risk of cancer. Some isoflavones found in soy protein have been identified as anti-cancer. Scientists believe that isoflavones may inhibit the growth of cancer cells. Isoflavones help prevent breast cancer, acting in this case as weak estrogens. They interact with receptors on estrogen-sensitive cells and protect them from stronger female estrogen. As a result, estrogens produced by the female body do not interact with tissues and are released without causing the growth and development of cancer cells.
Oncological diseases
Recent studies have identified the role of soy products in reducing the risk of developing tumors. Presumably, this effect is achieved due to isoflavones. They are able to minimize the likelihood of developing breast cancer due to their estrogen-like effect. By binding to the receptors of female sex hormones, isoflavones protect the body from the influence of estrogens on tissues, eliminating the possibility of the appearance of cancer cells in the breast that are formed under their influence.
The fading of the ovaries brings with it a trail of changes in the female body. Menopause, or menopause. What every woman should know in order to enter this period as comfortably as possible.
We are talking with a gynecologist-endocrinologist at the Interdistrict Department of Family Health, Yulia Medvedeva.
- Yulia Gennadievna, the ovaries reduce the production of estrogen, but we say about this age “the woman’s berry again.” What good is it when this is the beginning of various problems?
— I wouldn’t say that there are no advantages. Age also has many advantages. A woman gains life experience, she looks at everyday troubles more calmly, and becomes wiser. Stage - this is how menopause is translated. We are simply moving to another level. But not all women have a negative experience of menopause; a certain percentage endure this period without pathological symptoms. They simply become amenorrheic. Apparently, these women are genetically programmed this way.
— Is the onset of menopause menopause?
— Menopause begins from the last menstruation and beyond. Menopause and menopause are synonyms.
How does menopause usually go? What is the woman experiencing?
— Menopause is a symptom complex that not only changes the female genital area, but also many other organs and systems. For example, if until the age of 40 a woman had no risk of myocardial infarction, now the risk increases significantly, and these diseases are more severe than in men. Immediately, as a rule, blood pressure rises and migraines occur. In women with low estrogen levels, the bone apparatus suffers: osteopenia develops, leaching of calcium from the bones. When we do densonometry at the age of 40-45, we see osteopenia in 70% of patients. Today it is osteopenia, and a year later osteoporosis, that is, the risks of fractures of the femoral neck and lumbar vertebrae increase. But the first thing that suffers, I repeat once again, is the cardiovascular system. As soon as estrogen levels drop, heart disease develops.
“Then every woman in our country would have a heart condition.”
— Our women are not examined. And after all, everyone has a different supply of estrogen, everything is individual. But the heart is the first to be hit; with the onset of menopause, the number of heart attacks increases significantly. Then there may be vegetative manifestations: hot flashes, fever. Menopause progresses in different directions. Some may experience hot flashes during a normal cycle, while others do not have periods, but do not have hot flashes. This is genetically determined. A woman can look at her mother or grandmother and expect the same in herself.
— If we talk about the naturalness of the process, but with the “treat” approach, this causes bewilderment. Is it necessary to treat what is natural?
- But there is a pathological menopause. It is called a “symptom of menopausal disorders,” that is, it has vegetative disorders and needs to be treated. But you should definitely check with a doctor, regardless of the presence of menopause symptoms.
— Why does the body react so sharply to a decrease in estrogen levels?
— Because throughout the body there are estrogen receptors that must receive this hormone. They are found in bones, joints, heart muscle, and blood vessels.
— They talk about the pathological and physiological course of menopause. What is the difference? And what is more natural: to experience a spectrum of vasomotor difficulties or to go through menopause unnoticed?
“I think it’s incorrect to ask that.”
- Why?
- Because it is genetically determined. How can we judge that one has crooked legs, the other has straight ones - which one is healthier and more genetically correct, if everyone in her family has crooked legs? All people are individual, and women cannot be approached with one standard. If she has vegetative symptoms, we must correct them. If they are not there, the woman will continue to live in peace, and we must examine her according to the standards and be calm if these indicators do not yet require correction. But examinations must be done annually. We cannot know what kind of health a woman will have next year.
- Let's be honest. When a woman comes to the gynecologist for MHT (menopausal hormone therapy), she is very often not prescribed any tests.
- How so? There is an order from the Ministry of Health - screening before prescribing HRT. There should be a mammogram with a shelf life of no more than a year, cytology with a shelf life of a year, biochemistry with the lipid spectrum of the blood, a coagulogram and blood insulin, it is advisable to look at it. This is what will determine whether hormone therapy is allowed. But if a woman does not really ask for hormonal drugs, then there is no need to persuade her, because the risk of negative manifestations from the female reproductive system for some is very high.
— There are studies that claim that hormone therapy during menopause in some cases increases the risk of cancer in women.
“But there are other studies, the statistics are still controversial. There is no clear data yet. But our Ministry of Health has included hereditary cancer in the list of contraindications. If a woman has a history of surgery for cervical cancer, or close relatives have had it, this is an absolute contraindication. No need to invent anything, we work according to orders.
— Does hormone therapy always solve problems?
- The doctor must decide this one-on-one. There is a whole range of contraindications to hormonal therapy.
- But in other cases, HRT solves the problems of women in menopause?
- Yes.
— How long can hormone therapy last without harm to health?
— This is all decided by the doctor during individual observation. The safe duration of use is considered to be 5 years. And then the cards will fall. Ideally, of course, the longer, the better, because you maintain youth. There are women who have been taking synthetic drugs for 7-8 years. And there are those in whom you see bad mastopathy, hyperplasia, which means you need to cancel it right away. That's what observation is for.
— How often should a woman undergoing MHT see a doctor?
- At the first appointment in a month and then once every six months.
— What is your opinion about the fact that hormone therapy should be started in advance, without waiting for the unpleasant manifestations of menopause?
- Now, according to the latest recommendations, only during the period when the last menstruation ends, and not earlier than a year later. It is hormonal therapy.
— What if a woman begins to experience negative feelings?
— Herbal medicines exist.
— They may not relieve symptoms or help the woman, but you do not recommend taking hormones, what should I do?
— We need to select herbal medicines; there is a wide range of them now. Someone will help.
— Are synthetic hormones and their plant forms, herbal medicine in the form of dietary supplements, equally effective? Are there any studies confirming the effectiveness of herbal remedies in menopause?
- These are phytoestrogens and it doesn’t matter what they are called. There are many studies that show their effectiveness. When they give lectures on menopause, no one calls them dietary supplements. Their effect is still hormone-like, but not all dietary supplements have such an effect. Phytoestrogens do not have the same obvious side effects as hormones. They will suit a wider range of women and are the place to start.
— If a woman is not worried about anything, is it really necessary to go to the gynecologist because her period is over?
— According to the orders, once a year a woman must come to the gynecologist, undergo cytology and have a mammogram or ultrasound of the mammary glands, depending on her age. But in general, people come to us mainly with complaints about pathological manifestations of perimenopause, and then we understand where to go next and how to help. As a rule, when the cycle is disrupted, their manifestations immediately begin. This happens simultaneously.
— Does this mean that from now on you can not use protection?
- No, it doesn’t mean that. A disruption of the cycle does not mean that independent ovulation cannot occur; contraception for women 45+ must be considered. The doctor picks her up.
- But can you live without hormone therapy?
- Can.
- Sometimes hormones are not allowed. What to do then?
— There are microdoses, but they, as a rule, do not remove hot flashes, they are only to maintain the cardiovascular system. And then there is a placebo effect, and the woman feels better. Often hot flashes subside over time.
— Give general advice to women who have entered or who are yet to enter the mature stage of life.
- Come and talk to the doctor. Everyone is individual, you can’t buy a drug like from a friend. Sometimes these symptoms mask other endocrine problems, such as thyroid disease. There are vegetative problems: memory loss, cycle disorders, so I prescribe TSH to my patients, and some are diagnosed with thyroid disease. Therefore, you cannot independently treat menopause with female hormones; it could be other endocrine diseases. Such cases happen in practice.
Interdistrict Family Health Department
Consultations, diagnosis and treatment for women in menopause.
Make an appointment by phone; 8 (3519) 34 - 04 - 23.
Address: Southern complex of the State Autonomous Institution "City Hospital No. 2", st. Truda, 36.
Cherepanova N.S., press service of the State Autonomous Institution "City Hospital No. 2 of Magnitogorsk"
special instructions
- There is not enough data on alcohol intake during Bonisan therapy
- Bonisan is intended for sale in pharmacy chains without a doctor's prescription
- Bonisan is not addictive
Storage conditions for Bonisan
Bonisan should be stored out of the reach of small children. Shelf life 2.5 years
* Isoflavones are natural phytoestrogens compounds from soybeans. Taking isoflavones reduces the risk of osteoporosis in women over 40 years of age. Soy isoflavones help reduce the risk of osteoporosis by preventing thinning and fragility of skeletal bones. In addition, they help maintain calcium in the body. Soy isoflavones block excess enzymes that promote the growth of tumor cells in hormone-dependent tumors, thereby reducing the likelihood of developing an oncological process. The active components of Bonisan help prevent strokes and heart attacks: they prevent the development of vascular atherosclerosis.
In addition, soy isoflavones can delay the onset of menopause. They help get rid of nervous tension, slow down aging, and improve skin condition. Other drugs from the group Hormone replacement therapy drugs, phytoestrogens Other drugs from the ANTI-AGE group drugs used in preventive medicine and
Instructions for use Bonisan
Prevention of osteoporosis in women after 50-55 years. 1 capsule Bonisan 2 times a day for 3-6 months. Prevention of cardiovascular diseases. 1 capsule Bonisan 2 times a day for 2 months / 1 month break / 2 months. Or 4 months in a row (if atherosclerosis is detected). Prevention of hot flashes. 1 capsule Bonisan 1 time per day for 2-3 months. Prevention of osteoporosis in women after 40 years. 1 capsule Bonisan 1 time per day 1 month / 1 week break / 1 month. Prevention of memory loss and attention. 1 capsule Bonisan 1 time per day for 4-6 months.
Bonisan should be taken 1 capsule after meals, once a day, with a sufficient amount of water. The course of treatment is 30 days. Repeat course in a week.
You can drink Bonisan no more than twice a year.
How many courses to take the drug and its dosage will be determined solely by the attending physician.
Menopause
Menopause is a time in a woman's life that signals the end of her menstrual period and her ability to bear children. A woman officially enters menopause without a period after a full year.
Perimenopause and menopause symptoms, including uncomfortable bloating, can begin up to 4 years before menopause as hormone levels drop. Luckily, there are ways to relieve menopausal bloating and discomfort.
- What is bloating?
- Causes
- Water retention versus gas retention
- Prevention and relief
- Bloating or weight gain?
- When to see a doctor
- What is bloating?
Bloating is uncomfortable pressure in the abdominal area caused by extra air or fluid in the gastrointestinal tract. It may feel like fullness or tightness.
In some cases, bloating can cause a person's stomach to swell. A person may also experience temporary weight gain from bloating.
Causes
Water retention and gas retention can be the cause of menopausal bloating.
Menopausal bloating usually has one of two main causes: water retention or gas retention. Both can cause bloating during menopause.
A woman's hormone levels often fluctuate during perimenopause, which is the time leading up to menopause when a woman's hormone levels decline. Elevated estrogen levels can cause water retention, which in turn can cause bloating.
Unfortunately, estrogen is not the only cause of menopause bloat. During and after menopause, bloating can also be associated with changes in the gastrointestinal tract. These changes can be caused by many things, including:
- changes in diet or appetite
- slow digestion
- stress associated with menopause
- swallowing air
- other health conditions
Any of the above can lead to bloating due to excess gas.
