pharmachologic effect
The active ingredient of the drug is an amino acid, which is produced in the human body and helps regulate metabolism and normalizes the processes of protective inhibition in the central nervous system. Under its influence, the level of psycho-emotional stress in the body decreases, performance increases, and the severity of conflict and aggressiveness decreases. Taking the medicine, the patient notes normalization of falling asleep and improved mood. The substance reduces the severity of vegetative-vascular disorders, in particular during menopause . The condition of general cerebral disorders in people after a stroke or TBI improves. The product also reduces the toxic effects of alcohol on the body.
Vitamin B1 helps normalize the nervous system, stimulates mental performance and thinking processes.
Vitamin B6 normalizes brain functioning and helps overcome irritability and fatigue.
Vitamin B12 accelerates the processes of renewal of the structure of nervous tissue, improves attention and memory. This substance takes part in the production of acetylcholine, that is, a neurotransmitter that determines the processes of learning, memory, etc.
Glycine forte 500 mg lozenges 60 pcs. evalar
pharmachologic effect
Metabolic agent.
Composition and release form Glycine forte 500 mg lozenges 60 pcs. evalar
1 cheek tablet contains:
- active substance glycine - 500 mg;
- excipients: aspartame, croscarmellose sodium, copovidone, magnesium stearate, sorbitol.
Buccal tablets 500 mg. 10 or 30 tablets in a blister pack made of polyvinyl chloride film and printed varnished aluminum foil.
1, 2, 3, 5, 6, 9, 10 blister packs of 10 tablets or 1, 2, 3 blister packs of 30 tablets, together with instructions for use, are placed in a cardboard pack.
Characteristic
The life of a modern person is dynamic, eventful and, moreover, filled with mental and emotional stress. Work, study, preparation for exams, an upcoming conference, an important meeting - this is not the entire list of reasons that cause nervous tension and mental fatigue.
Normally, in a person, the influence of the parasympathetic nervous system (calm) predominates, but with prolonged nervous stress, the balance is disturbed and the sympathetic nervous system (activity) becomes more active. As a result, the increased activity that a person needs to solve specific problems becomes a predominant state of overexcitation, which is difficult to manage. At the same time, concentration decreases, a feeling of anxiety appears, and it becomes increasingly difficult to find a way out of a difficult situation. Mental stress, inability to sleep and relax lead to exhaustion of the nervous system. It is difficult to cope with a problem of this level on your own. Glycine is widely used throughout the world to solve these problems - as a non-drug that helps reduce stress and mental strain, and in significant quantities.
produces Glycine forte Evalar, similar to foreign ones - with a high glycine content, which has a positive effect on the activity of the nervous system: helps to equalize the processes of excitation and inhibition in the cerebral cortex, increase mental performance, reduce increased irritability, and normalize sleep.
For the first time, the effect of glycine is enhanced by the maximum dosage of vitamins B1, B6, B12 in the same ratio as they exist in nature. B vitamins have a beneficial effect on the nervous system and help counteract stress.
The combination of glycine and B vitamins in one tablet is necessary for our brain during increased mental and psycho-emotional stress.
Glycine forte Evalar tablets are easy to use and easily dissolve, which helps to achieve the effect more quickly - reducing nervous tension and increasing mental performance.
"Glycine forte Evalar" does not form dependence upon long-term use, since it contains active components natural to the body.
Directions for use and doses
Sublingual or buccal 250 mg (in tablets or in powder form after crushing the tablets).
For children, adolescents and adults with psycho-emotional stress, decreased memory, attention, mental performance, mental retardation, and deviant forms of behavior, glycine is prescribed ½ tablet 2-3 times a day for 14-30 days.
For functional and organic lesions of the nervous system, accompanied by increased excitability, emotional lability and sleep disturbances, children under 3 years of age are prescribed ¼ tablet 2-3 times a day for 7-14 days, then ¼ tablet 1 time per day for 7-10 days. Daily dose - 100-150 mg, course dose - 2-2.6 g.
Children over 3 years of age and adults are prescribed ½ tablet 2-3 times a day, the course of treatment is 7-14 days, it can be increased to 30 days, if necessary, the course is repeated after 30 days.
For sleep disorders, ¼-½ tablets are prescribed 20 minutes before bedtime or immediately before bedtime (depending on age).
For ischemic cerebral stroke: during the first 3-6 hours from the onset of stroke, 1 g (4 tablets) is prescribed buccally or sublingually with 1 teaspoon of water, then for 1-5 days, 1 g / day (4 tablets), then over the next 30 days, ½-1 tablet 3 times a day.
In narcology - ½ tablet 2-3 times a day for 14-30 days. If necessary, courses are repeated 4-6 times a year.
Pharmacodynamics
A non-essential amino acid, a central inhibitory neurotransmitter. Improves metabolic processes in brain tissue, has an antidepressant and sedative effect. It has glycine- and GABA-ergic, alpha1-adrenergic blocking, antioxidant and antitoxic effects; regulates the activity of glutamate (NMDA) receptors, thereby reducing psycho-emotional stress, aggressiveness and conflict; improves social adaptation and mood; makes it easier to fall asleep and normalizes sleep; increases mental performance; reduces the severity of vegetative-vascular disorders (including during menopause) and cerebral disorders in ischemic stroke and traumatic brain injury, the toxic effect of ethanol on the central nervous system.
Pharmacokinetics
Easily penetrates into most biological fluids and body tissues, including the brain, and does not accumulate. It is quickly destroyed in the liver by glycine oxidase to water and carbon dioxide.
Indications for use Glycine forte 500 mg lozenges 60 pcs. evalar
Stressful conditions (including psycho-emotional stress), decreased mental performance, deviant forms of behavior in children and adolescents, various functional and organic diseases of the nervous system, accompanied by increased excitability, emotional instability, decreased mental performance and sleep disturbances: neuroses, neurosis-like conditions, consequences of neuroinfections and traumatic brain injury, perinatal and other forms of encephalopathies (including alcoholic origin).
Ischemic stroke.
In narcology - as medicines that increase mental performance and reduce psycho-emotional stress during the period of remission in cases of encephalopathy, organic lesions of the central and peripheral nervous system.
Contraindications
Hypersensitivity.
With caution: arterial hypotension.
Effect on the body
- increases mental performance and resistance to stress;
- reduces nervous and mental tension;
- improves sleep.
special instructions
In patients with a tendency to arterial hypotension, the prescription is made in smaller doses and with blood pressure under control; when it decreases below the usual level, the intake is stopped.
Side effects Glycine forte 500 mg lozenges 60 pcs. evalar
Allergic reactions.
Drug interactions
Reduces the severity of side effects of antipsychotic drugs (neuroleptics), anxiolytics, antidepressants, hypnotics and anticonvulsants.
Indications for use
Glycine Forte Evalar is used as a dietary supplement, providing an additional source of glycine for the body. It is recommended to take tablets during periods of severe stress, to overcome the symptoms of neuroses , vegetative-vascular dystonia , and severe excitability. Also indicated for use is the condition after TBI, stroke, various forms of encephalopathies . Used to treat adolescents with deviant behavior.
special instructions
Before using this remedy, the patient should consult a specialist.
With prolonged use of Glycine Forte Evalar, the patient does not develop dependence on the drug, since it contains components that are natural to the body.
People with a tendency to arterial hypotension should take smaller doses of Glycine Forte and at the same time control blood pressure levels. If your blood pressure drops to a lower level than normal, you should stop taking the tablets.
All about the dosage form
Unfortunately, not all people carefully study the instructions for the drug when purchasing medications. But in vain. Even when products have the same active substance, their indications and method of use can be very different. And a clear example of this is the drug Glycine, which is produced by the company BIOTICS. The peculiarity of the amino acid is that it is poorly absorbed by the digestive system. If you take the drug by swallowing it with water, it will not have any effect. Glycine, which is produced by the BIOTICS company, is significantly different from other products. It's all about microencapsulation technology, which was developed and patented by the company (the RF patent number is indicated on each package).
Reviews of Glycine Forte Evalar
In most cases, patients leave positive reviews about Glycine Forte online, noting its positive effect on the nervous system, as well as on the human body in general. There are many reviews from students that these tablets help to activate mental abilities and cope with mental stress more effectively. Some reviews note that the drug is more effective than regular Glycine. Reviews from doctors about this medicine are also mostly positive.
GLYCINE FORTE reviews
Greetings to all readers of the review about the dubious drug GLYCINE FORTE!
For a long time, I didn’t go into detail at all about what kind of drug this Glycine is sometimes prescribed to us by doctors, what its main components are, and whether it even works. Since the doctor prescribed it, it means it’s necessary. He knows better, he’s a doctor! I remember that during my school or student years I took Glycine, supposedly to calm and improve brain activity. Well, why not “treat yourself” with this remedy? The tablets are small, sweet, easy and safe to take.
Yes, today everywhere both old and young people are prescribed this mysterious Glycine so that they can “sleep better,” but is there a real need for it and does it work at all? I asked myself these questions not so long ago, when I myself began to have serious nervous problems.
I don’t remember exactly why and when I took this supplement in my youth, but several years ago a pediatric neurologist prescribed Glycine to my two-year-old son. He had increased excitability, according to the doctor, he often cried, and sometimes he could hit me. The neurologist characterized this manifestation of herself and her character as “hyperactivity” and prescribed Glycine with other medications.
There was an effect, but it was delayed and I do not exclude that it was from other drugs that were not dietary supplements, but worked specifically to calm the nervous system. I didn’t see Glycine’s great merit in this. And with age, the child’s worries went away, so maybe there was no need to panic?
For the second time in recent years I took Glycine two months ago. I have already written many times that due to nervousness, I began to have difficulties with cerebral circulation, and my cervical osteochondrosis worsened. Plus, all these ailments increased my irritability even more. While studying material about my illnesses, I remembered about Glycine, that it seems to calm and improve metabolism in the brain. So maybe it will be useful for me too? At the pharmacy I bought not just Glycine, but Glycine Forte from Evalar. So that immediately and for sure))) That’s naive.
Glycine Forte costs three times more than regular Glycine. I paid 156 rubles for a pack of 60 tablets. Loud and positive promises are already written on the box:
- increased mental performance
- reduction of nervous and mental tension
- improved sleep
- improvement of blood circulation in the vessels of the brain
However, I would like to note right away that Glycine Forte is a dietary supplement, and not a medicine or a drug whose effect has not been scientifically proven. Okay, so what? I started taking 1 tablet 2 or even 3 times a day. This is not difficult to do, because each tablet is round in shape and sweet. It is advisable to dissolve Glycine Forte under the tongue. Since the supplement also contains vitamins B1, B6, B12, which supposedly help glycine to be absorbed better, each tablet has a specific smell)
Unfortunately, I didn’t notice any effect on myself either after a week or two. I slept well before the appointment, but my nerves and general emotional state did not stabilize. There is nothing at all to say about improving cerebral circulation; I am still undergoing treatment and am far from being treated with Glitsinchik.
Later, I came across a consultation with a neurologist, a scientist. So he spoke in detail and honestly about the substance glycine. It turns out that it is already produced in our brain. Some people just don't have enough of it. But no pill can increase its level in our body! And all because of some barrier in the brain. That is, if we ate Glycine and it entered the blood through the gastrointestinal tract, then it will not be delivered further to the brain.
But on the contrary, it can go from the brain into the blood, but this does not affect our well-being in any way. Some people say that Glycine helped them and they began to feel better. The doctor also comments on this - the placebo effect is triggered, that is, self-hypnosis. “I’m being treated, I’m taking a magic pill, so it will help.” No more. From a scientific and medical point of view, Glycine from a tablet cannot get into our brain. Then everything fell into place.
So I conclude that regular Glycine, and even more so Forte from Evalar, are absolute dummies on which the manufacturer makes a lot of money. After all, it turns out that I paid 150 rubles for a sweetener with some additives.
Do you believe in the action of Glycine?
