Pilex - antihemorrhoidal combination drug


Pharmacological properties

Pilex ointment for the treatment of hemorrhoids and anal fissures for topical use

Combined herbal preparation. The composition of the active substances includes extracts and powders of medicinal plants: Mimosa pudica, Eclipta alba, Chinese twig, Calendula officinalis

which help reduce pain, bleeding and inflammation in the area of ​​hemorrhoids, and accelerate the healing process of anal fissures. Camphor improves microcirculation, thereby having an antiseptic, local analgesic and anti-inflammatory effect.

Pylex tablets are a multicomponent herbal remedy, the effectiveness of which is due to the complex action of its components. The medicinal plants that make up Pylex tablets have anti-inflammatory, decongestant, venotonic, wound-healing, membrane-stabilizing, antimicrobial and antioxidant effects. When using Pylex tablets, there is a decrease in venous stagnation, swelling, hyperemia and other signs of the inflammatory process in acute and chronic hemorrhoids in the acute stage. The drug helps improve microcirculation, accelerate the healing process, and reduce the likelihood of infection. Thanks to its calming and mild laxative effect, the use of the drug Pilex facilitates the process of defecation in case of chronic constipation accompanying hemorrhoids.

Instructions for use

Pilex as a drug containing a mixture of various herbal components in the form of active substances helps to increase the tone of the vein walls, significantly reduces swelling associated with venous insufficiency, and reduces pressure in the liver venous system.

When using the drug in the form of a topical ointment, the components contained in it have a local analgesic, anti-inflammatory, disinfectant and antiseptic effect.

Indications for use

Pilex in tablet form is used for the following diseases:


  • Hemorrhoids (inflammation and bulging of the veins in the rectum);

  • Cracks in the anus, proctitis;
  • Varicose veins (a pathology manifested in the formation of protrusions and an uneven increase in their lumen due to a malfunction of the valve apparatus);
  • Thrombophlebitis (vein blockage and inflammation).

Pilex in the form of an ointment is used in the following cases:

  • For hemorrhoids and proctitis;
  • When anal fissures occur.

Mode of application

Pylex tablets for hemorrhoids are taken 2 times a day. A single dose is 2 tablets. The standard course duration is 2-4 weeks. During an exacerbation of the disease, it is permissible to increase the dosage to 3 tablets 3 times a day.

This regimen is carried out for no longer than 1 week, after which they move on to the standard dosage regimen. The exact dosage and treatment period are determined by the doctor.

The tablets are taken in the morning and in the evening after meals. During an exacerbation, with an increase in the number of doses, the drug is taken 3 times, also after lunch. The tablets are swallowed whole or chewed, then washed down with the required amount of water. When used together with ointments and tablets, the therapeutic effect is enhanced.


Pylex ointment is applied using the applicator included with the drug 2 times a day (at the beginning and end of the day) with a course duration of 14 days.

The procedure is carried out before or after defecation and after hygiene procedures in the anal area. After applying the ointment, the applicator is thoroughly washed and stored dry until next use.

Release form, composition

Paylex in the form of tablets having a round biconvex shape and color from light to dark brown with inclusions, packaged in plastic bottles, contains the following components:

  • Extract of plant raw materials, processed with steam, containing Commelina loosefolia, seeds of Caesalpinia bonducova, Mimosa pudica, corms of Amorphophallus campanulata, resin of Blumea malaya;
  • Purified mumiyo powder (16 mg), commiphora mukul kamede resin (130 g), Indian azadirachta leaves (7 mg);
  • Extract of the fruits of Emblica officinalis and Cassia tubularis (16 mg each), barberry roots (32 mg), peel of the fruits of Terminalia ballerica and chibula (16 mg each), bark of Bauhinia variegata variegata (16 mg), flowers of Mesua ferruginosa (3 mg).

As auxiliary components, the tablets contain microcrystalline cellulose, magnesium sterol, copovidone, colloidal silicon dioxide, sodium carmellose.

Paylex in the form of an ointment is available in 30 g laminated foil tubes with an attached applicator, has a light gray or cream color, and has a camphor scent. Intended for topical use and consists of the following components (per 30 g):

  • Liquid extract, similar in composition to plant extract tablets (3.9 g);
  • Racemic camphor (0.368 g);
  • Zinc oxide and sodium tetraborate (0.3 g each);
  • Whole plants of white eclipta and Chinese twig (23% each);
  • Mimosa pudica (38%);
  • Calendula flowers (16%).

As excipients, the ointment contains: sodium methyl and propyl parahydroxybenzoate, propylene glycol, stearyl and cityl alcohol, cetomacrogol, petroleum jelly, liquid paraffin, purified water.

Interaction with other drugs

The activity of the drug is determined by the mutual combination of components. Since the medicine is of a plant nature and consists of many components that mutually influence each other, it is almost impossible to conduct a study of each of the components of the medicine with other substances and drugs.

In general, Pilex ointment and tablets can be used in a course of complex antihemorrhoidal treatment, enhancing the effect of other medications.

Directions for use and dosage

Pills:

Inside.

Adults: 2 tablets 2 times a day after meals.

The duration of the course of therapy is 14 days.

If necessary, the course of therapy can be extended.

Ointment:

Apply with an applicator before or after bowel movements and toilet in the anal area, 2 times a day (morning and evening). The duration of treatment is 14 days. The applicator is thoroughly washed with soap and warm water and kept dry until next use.

The simultaneous use of Pilex tablets increases the effectiveness of therapy.

Pilex ointment 30g No. 1

Name

Pylex.

Description

The ointment is yellowish-gray in color, uniform in consistency with dark inclusions, and has the smell of camphor.

Release form

Ointment.

Dosage

30 g.

pharmachologic effect

Other remedies for the treatment of hemorrhoids and anal fissures for external use. ATX code: C05AX.

Pharmacodynamics

Multi-component Ayurvedic remedy. Pilex ointment has an anti-inflammatory and astringent effect.

Pharmacokinetics

There are no data on the pharmacokinetics of the multicomponent Ayurvedic drug Pilex in ointment dosage form. The activity is due to the combined action of its components. Since the activity of the drug cannot be completely attributed to any one substance, pharmacokinetic studies of Pilex ointment are not feasible.

Indications for use

As part of the complex treatment of stage I-II hemorrhoids and anal fissures.

Directions for use and doses

Locally, for adults 2 times a day (morning and evening), as well as before and after each act of defecation. Apply using an applicator to the mucous membrane of the rectum and hemorrhoids, including inflamed, reddened and hardened areas. The duration of treatment is determined individually depending on the severity of the pathological process. The minimum duration of treatment is 14-28 days. If necessary, the course of therapy can be extended after consultation with a doctor.

Precautionary measures

There may be a short-term burning sensation at the application site, which goes away on its own after a few minutes. The therapeutic effect of the drug Pilex develops gradually. However, if you do not feel any improvement when using the product, or if your symptoms worsen, consult your doctor. You should also consult a doctor if you have severe pain or bleeding. Pilex ointment contains sodium methyl parahydroxybenzoate and sodium propyl parahydroxybenzoate, which can cause allergic reactions (delayed reactions may develop). Pilex ointment contains cetostearyl alcohol, which may cause local skin reactions (eg, contact dermatitis). Pilex ointment also contains propylene glycol, which may cause skin irritation. Pregnancy and breastfeeding The drug Pilex ointment is not used in pregnant women and during breastfeeding, since there is no clinical experience and the safety profile has not been studied. Check with your doctor before taking any medicine if you are pregnant or breastfeeding. Use in children The safety and effectiveness of using the drug Pilex ointment in children have not been established, therefore it is not recommended to prescribe it to children and adolescents under 18 years of age. Use in the elderly and patients with impaired renal or liver function No data available.

Interaction with other drugs

No incompatibility with other drugs has been identified; however, the simultaneous use of other antihemorrhoidal drugs for topical use is not recommended. Effect on the ability to drive vehicles or potentially dangerous machinery The drug Pilex does not affect the ability to drive vehicles, use machinery, or perform other work that requires attention and good coordination.

Contraindications

Individual hypersensitivity to the components of the drug. Pregnancy and breastfeeding. Massive bleeding from hemorrhoids, acute thrombosis of hemorrhoids. Children under 18 years of age.

Compound

Active components: in 1 g of ointment Liquid extract combined 130.0 mg*

Mimosa pudica herb (11:1)50 mg

eclipta white herb (Eclipta alba) (6.66:1) 30 mg Chinese twig aerial part (Vitex negundo) (10:1) 30 mg calendula officinalis flowers (Calendula officinalis) (5:1) 20 mg Powders: camphor 12.25 mg sodium tetraborate 10.0 mg zinc oxide 10.0 mg * - which is steamed with an extract of a mixture (in a ratio of 1:10 to water) of the following plant materials: Indian azadirachta seeds and leaves (Melia azadirachta), Ailanthus excelsa bark, Blumea resiniferous resin (Blumea balsamifera), eclipta grass (Eclipta alba), shallot leaves (Allium ascalonicum), calamus rhizome (Acorns calamus), black nightshade grass (Solanum nigrum), mimosa pudica grass (Mimosa pudica). The extractant is water. Excipients: propylene glycol (E 1520), cetostearyl alcohol, yellow petrolatum, petroleum jelly, macrogol cetostearyl ether (cetomacrogol 1000), sodium methyl parahydroxybenzoate (E 219), sodium propyl parahydroxybenzoate (E 217), purified water.

Overdose

Cases of drug overdose have not been described.

Side effect

Allergic reactions are possible. After applying the ointment, a slight burning sensation and tingling around the anus may occur for 10-15 minutes. Local reactions may develop: irritation of the skin and mucous membranes, contact dermatitis. If these or other reactions occur, you should consult a doctor.

Storage conditions

Store at temperatures from + 10 to + 30 ° C in a place protected from moisture. Keep out of the reach of children.

Buy Pilex ointment in tubes 30g in pack No. 1 in the pharmacy

Price for Pilex ointment in tubes 30g in pack No. 1

Instructions for use for Pilex ointment in tubes 30g in pack No. 1

Side effects

When using the drug, allergies may occur. After applying the ointment, a burning sensation is sometimes observed in the anus, which is acceptable and is not a signal to cancel the course of treatment.

Rarely, while taking tablets, dyspeptic symptoms (stomach upset, nausea and vomiting) occur, which stop after discontinuation of use. If these side effects worsen or new ones not listed in the description occur, it is recommended to immediately notify a specialist.

Contraindications

Pilex is contraindicated for use in the following cases:


  • Allergic reaction to individual components of the drug;

  • Massive bleeding of hemorrhoids;
  • Erosion and ulcers of the gastrointestinal tract during exacerbation;
  • Acute thrombosis of hemorrhoids;
  • Children under 18 years of age (since there are no safety data available yet).

During pregnancy

No studies have been conducted on the effects of Pilex on the body of pregnant women and the fetus, as well as its presence in breast milk. For this reason, its use is undesirable during pregnancy and lactation .

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