Oxolinic ointment: instructions for use, indications, price, reviews for papillomas, warts, stomatitis

pharmachologic effect

This product contains the active ingredient oxolin , which demonstrates antiviral activity against herpes , herpes zoster , and influenza (mainly type A2). Sensitivity to oxolin of adenoviruses, molluscum contagiosum and warts of infectious origin has been noted.

This remedy is used externally and has an antiviral effect. The mechanism of influence of the active substance is based on its ability to block the binding sites of the influenza virus with the cell membrane. The product blocks viruses on the surface of membranes, preventing the virus from entering cells.

Oksolin

Oxoline or oxolinic ointment (in “chemical” language the name of this substance sounds like dioxotetrahydroxytetrahydronaphthalene) is an antiviral drug for local and external use. It has a destructive effect on the influenza virus (the condition for this is direct “face-to-face” contact), inhibits reproduction - the formation of viral copies. Herpes simplex and herpes zoster viruses, infectious wart and molluscum contagiosum viruses, and adenoviruses are also not indifferent to the action of oxolin. But still, the main area of application of the drug is the prevention of influenza. Influenza is a type of acute respiratory viral infection, accompanied by high morbidity and the likelihood of complications that aggravate the course of the disease. Due to the fact that in the initial phase of the disease, patients walk around the street with might and main, including visiting public places, the infection spreads quickly. In this regard, the issue of protection against influenza during periods of epidemic trouble is more relevant than ever. One of the most accessible methods of preventing influenza should be considered the intranasal use of oxoline, which not only prevents the incorporation of viruses into epithelial cells of the respiratory tract, but also exhibits pronounced virucidal activity against influenza viruses of types A and B. “Oxolinka” is an antiviral drug familiar to most us since childhood. Long-term practice of using this drug has strengthened in the minds of many doctors and pharmacists the opinion that oxolin is more a tool of mechanical protection than a specific antiviral agent. However, the very fact of the presence of oxolinic ointment on pharmacy shelves for many years clearly testifies in its favor. Yes, and there is still some kind of evidence base for this drug. Oxolin was first synthesized in 1964 at the Moscow Scientific Research Chemical and Pharmaceutical Institute.

Clinical trials of the drug have confirmed its safety and effectiveness in the treatment of certain dermatological and ophthalmological viral infections. Subsequently, the activity of oxoline against the influenza virus was demonstrated. The effectiveness of the drug was assessed by the degree of its influence on the duration of the main clinical manifestations of the disease: febrile temperature, intoxication of the body, respiratory symptoms. As a result of scientific research, it was established for certain: local use of oxolinic ointment did not affect the duration of fever and symptoms of intoxication, but shortened the duration of a runny nose, reduced exudation and facilitated nasal breathing. In clinical trials of oxolin as a prophylactic during influenza epidemics, it was demonstrated that the effectiveness of the drug depends on the mode of its use. Irregular, sporadic use of oxolinic ointment was practically useless. Regular use of the drug with a frequency of at least 2 times a day for three weeks contributed to a milder course of the flu, which was manifested by a decrease in the duration of the temperature reaction. It is important that when oxolinic ointment is applied to the skin or mucous membranes, it does not have a locally irritating or resorptive toxic effect. Only 5% of oxoline is absorbed through the skin, about 20% through the mucous membranes. The drug does not accumulate in the body and leaves it completely within 24 hours, calling on the kidneys to help. To treat warts, they are lubricated with 3% ointment 2-3 times a day for 0.5-2 months. To prevent influenza, a 0.25% ointment is used, which is applied to the nasal mucosa 2-3 times a day during periods of epidemiological trouble or in case of direct contact with an infected person. Viral rhinitis is treated in the same way for 3-4 days.

Pharmacokinetics and pharmacodynamics

It is not toxic, there is no systemic effect if it is applied topically. The active substance does not accumulate in the body. If the drug is applied to the mucous membranes, only 20% of the drug is absorbed. After application to the skin, only 5% of the product is absorbed. It is not irritating if the required amount and concentration have been applied and the skin at the application site has not been damaged.

Does not accumulate. Excretion occurs through the kidneys within one day.

Composition and dosage forms

The ointment is a homogeneous viscous substance of yellowish or white color. Contains the active substance - oxolin. Its concentration in 1 g of the drug, depending on the purpose, is 0.25 or 3%.

The medicine is produced by the medical industry in two forms:

in plastic or metal tubes weighing 10 and 30 g containing a 3% drug: for the treatment of skin;
in tubes of 10 g containing ointment at a concentration of 0.25%: for the treatment of mucous membranes.

The ointment base contains petroleum jelly or paraffin. During long-term storage, the product may acquire a pink tint, which does not affect its pharmacological properties.

Indications for use of Oxolinic ointment

The following indications for the use of Oxolinic ointment are noted:

viral diseases of the skin and eyes;
rhinitis of viral origin (inflammatory processes of the nasal mucosa);
lichen squamosus , vesicular and herpes zoster ;
molluscum contagiosum;
the appearance of warts ;
Dühring's dermatitis herpetiformis .

It is also used to prevent influenza, for which oxolinic ointment is applied during epidemics to prevent infection with the virus.

0.25% Oxolin is also used for stomatitis . This remedy is effective for stomatitis of herpes origin.

Therapeutic effect

Oxolin has a local antimicrobial and antiviral effect. Weaken herpes simplex viruses, adenoviruses, influenza pathogens, molluscum contagiosum and some others.

The drug is easily applied, distributed over the skin and mucous membranes, forming a thin, breathable, transparent film.

Being on the surface, oxolinic ointment prevents the penetration of pathogens from the outside into the epithelial cells.
By acting on the membranes of viral shells, the drug destroys their nucleic acids, blocking functionality and accelerating the death of pathogens.
It has a softening effect, reduces irritation and pain in the affected areas.

After application, the drug is partially absorbed through capillary vessels into the bloodstream. Inside the body it is completely neutral. Does not have a systemic effect, does not cause intoxication, does not accumulate in the blood and tissues. Oxoline particles are metabolized by the liver and are completely excreted in intestinal contents and urine within 24 hours.

Oxolinic ointment, instructions for use (Method and dosage)

If Oxolinic ointment is used, the instructions for use must be followed.

When treating viral keratitis , as well as adenoviral keratoconjunctivitis, it is necessary to apply 0.25% ointment behind the eyelid 1-3 times a day. Treatment is carried out for 3-4 days. If treatment is necessary for infants, you should definitely consult a specialist.

In order to treat viral rhinitis, you need to thoroughly lubricate the nasal mucosa 2-3 times a day for 3-4 days. For this, 0.25% ointment is used. The ointment is used similarly for children and adults to prevent influenza and ARVI . During a flu epidemic, it is necessary to practice lubrication for several weeks, and be sure to use the ointment when in contact with someone who has the flu.

Patients with different types of lichen and molluscum contagiosum should use a 3 percent ointment, which is applied 2-3 times a day to the affected areas. Treatment lasts from 2 weeks to 2 months, depending on the patient’s condition. Use during pregnancy for treatment and prevention should only be carried out after a doctor's prescription.

Use 3% Oxolinic ointment for warts . Apply to skin affected by warts. Reviews indicate that the medicine sometimes allows you to completely get rid of warts.

Indications

The main indication of oxolinic ointment is the prevention of infection with influenza and other acute respiratory viral infections in case of probable contacts with sick people or during seasonal epidemics.

The medicine has proven itself in the complex treatment of the following infections:

viral rhinitis, acute respiratory infections;
inflammation of the eyelid mucosa, keratitis, conjunctivitis;
skin warts;
scaly, herpes zoster and vesicular lichen;
Dühring's dermatitis;
molluscum contagiosum;
stomatitis of herpes origin.

The therapeutic effect of the ointment is most pronounced in the initial stages of the disease.

Analogs

Level 4 ATC code matches:
Florenal

Oftalmoferon

Oksolin

Zirgan

Oftan I'm coming

Poludan

You can find many different drugs that have similar effects. Analogues of Oxolinic ointment 3 percent - Alpizarin , Atsigerpin , Vartek , Virolex , Amiksin , Gerperax , Vivorax , Zovirax and many others. At the same time, there are no medicines containing a similar active ingredient on the market.

Side effects and interactions

Oksolin is well tolerated when used by children and adults. Negative reactions are extremely rare. In the first days of applying the drug, there may be a slight burning sensation of the mucous membranes and skin, a short-term increase in nasal discharge, decreased visual acuity, and increased lacrimation. In most cases, the discomfort gradually disappears on its own. Sometimes the ointment causes a bluish coating to appear, which is easily washed off with water.

When used together, oxolinic ointment and intranasal vasoconstrictor drops are likely to increase dryness of the mucous membranes. The problem can be solved by additional use of moisturizers.

Treatment and prevention of diseases with ointment does not cause disturbances in the speed of psychomotor reactions, concentration of attention, and does not affect the emotional state of patients. Using the drug does not require giving up work with high mental stress or driving.

Reviews of Oxolinic ointment

As a rule, users leave positive reviews about this product. Basically, the ointment is considered to be a good preventive measure, as well as an effective drug for the treatment of the common cold.

If Oxolinic ointment is used for papillomas , the reviews are also in most cases positive, but there are not so many such opinions. Sometimes they say that with long-term use the drug actually helps get rid of warts. As a positive point, the low price of the product is noted. The lack of a pronounced effect of treatment is mentioned as a negative.

Application

In the treatment of eye pathologies, lesions of the mucous membranes of the nasal cavity and mouth, as well as for the prevention of influenza, the drug is used in a concentration of 0.25%:

for keratitis and conjunctivitis, a thin strip of ointment is placed behind the lower eyelids 1–3 times a day;
intranasally: for the treatment of rhinitis and for the prevention of viral respiratory infections, a thin layer of the drug is lubricated in the nasal cavity;
for stomatitis: a small amount of ointment is distributed onto the affected areas, covering them from saliva with cotton swabs.

The drug in a 3% concentration is used in the treatment of skin diseases. It is applied in a thin layer or pointwise to areas affected by lichen, dermatitis or warts up to 4 times a day. If necessary, the skin is covered with sterile fabric breathable bandages.

The medicinal product does not require subsequent special rinsing from the skin and mucous membranes. The course of treatment depends on the severity of the disease and lasts from 2 to 10 weeks. For prevention, the product can be used once or periodically.

Oxolinic ointment is approved for use in children over 2 years of age. In some cases, in low concentrations under the supervision of a pediatrician, it can be used before this age.

Since a small part of the drug penetrates into the body, exceeding doses for external use does not lead to negative health consequences. If the ointment is accidentally swallowed, life-threatening situations also do not arise. To avoid disturbances from the digestive system, it is recommended to rinse the stomach with plenty of water and take enterosorbents. No antidotes are required.

Price of Oxolinic ointment, where to buy

The price of Oxolinic ointment 3% ranges from 30 to 90 rubles per tube, depending on the manufacturer. You can buy Oxolinic ointment 3 percent at any pharmacy. Oksolin 0.25% costs approximately 30-40 rubles. for 10 g

Online pharmacies in RussiaRussia
Online pharmacies in UkraineUkraine

ZdravCity

Oxolinic ointment 0.25% 10g OzonOzon LLC
73 RUR order

Pharmacy Dialogue

Oxolinic ointment 0.25% 10gGreen oak grove
32 RUR order
Oxolinic ointment 0.25% 10gNizhpharm JSC
65 rub. order
Oxolinic ointment 0.25% 10g Sintez (Kurgan) OJSC
58 RUR order
Oxolinic ointment 0.25% 10g Altaivitamins
15 rub. order
Oxolinic ointment 0.25% 10gOzon LLC
81 RUR order

An old, proven and effective remedy. Oxolinic ointment - what does it help with?

What does oxolinic ointment help with?

The main use is in the treatment and prevention of influenza.

In addition to treating a runny nose, oxolinic ointment helps with the following conditions:

• rhinitis of viral etiology, sores of the nasal cavity after a runny nose, acute respiratory infections, ARVI, chickenpox;

• in dermatology: lichen vulgaris, herpes zoster and blisters, psoriasis, herpes, candilomas, warts, spinules, dermatitis caused by herpes, molluscum contagiosum;

• in ophthalmology for inflammation of the eyeball, damage to the mucous membrane of the eyes with herpes, keratitis, conjunctivitis.

Important. Due to the absence of accumulation of the drug and systemic effect on the body, oxolinic ointment allows you to treat diseases that require the long-term influence of an antiviral drug without harm to health.

Before starting treatment, it is important to consult with a specialist, because with a bacterial infection there may be similar symptoms, but the ointment has no effect.

Prevention of flu and colds

Oxaline ointment helps in the early stages of acute respiratory infections, and is also effective as a preventive agent during quarantine for a viral infection.

How to use:

• using a cotton swab, apply a thin layer of ointment along the inner surface of the nose 1-2 times a day for prevention and 3-4 times if infection has already occurred;

• before applying a new portion of the drug, be sure to rinse the nasal cavity with saline solution (you can dilute ½ teaspoon in a mug of water at room temperature yourself or take a ready-made isotonic solution);

• if there is a high risk of infection, you can enhance protection by applying oxolinic ointment to the oral cavity. It is used more often in young children. For young children, you can lubricate the pacifier or apply it to the root of the tongue using a cotton swab.

In case of symptoms of sore throat, it is allowed to use ointment after gargling with antiseptic drugs or decoctions of anti-inflammatory herbs.

Oxolinic ointment for eye inflammation

For keratoconjunctivitis caused by a viral infection (usually adenovirus), 0.25% oxolinic ointment helps well. A course of treatment of 5-7 days consists of applying the product over the centuries up to 3 times a day.

It is important to remember that in case of eye inflammation caused by a bacterial infection, the effectiveness of oxolin is zero; the drug is prescribed only when a viral infection is specified. With a bacterial infection, purulent discharge is pronounced; with a viral infection, itching and burning of the eyes comes to the fore with minor discharge from the affected eye without any admixture of pus.

Oxolinic ointment helps with viral stomatitis

For the treatment of stomatitis of viral origin, the drug 0.25% is used. Each ulcer is carefully coated with ointment and a thin layer is applied to the entire oral cavity in order to prevent the formation of new aphthae.

Important. Before each application of the ointment, the oral cavity must be thoroughly cleaned:

• brushing teeth during stomatitis should be gentle, without excessive mechanical impact on the affected gums.

• Remove the resulting crusts using a cotton swab soaked in sterile oil. You cannot pick or pick out ulcers;

• Rinse your mouth with a decoction of chamomile, sage or a ready-made pharmaceutical antiseptic (furacilin, chlorhexidine).

• Lubricate the oral cavity with oxolin, paying special attention to ulcers. The course of treatment depends on the course of the disease and is carried out until the oral mucosa is completely healed. Important. When applying the drug, movements should be light and wet. Rubbing the product is not allowed.

• Solcoseryl is used at night.

Oxolinic ointment helps with warts

Treatment of warts with oxolinic ointment takes from 3 to 7 months. A 3% ointment solution is applied to the affected area.

Method of treatment

• Rinse the skin and wart thoroughly and dry with a towel;

• Apply ointment directly to the wart and the skin around it in a thin but dense layer;

• place a sterile gauze pad on top;

• place wax paper or polyethylene on a napkin;

• bandage well.

The procedure is carried out at least 2 times a day until the problem is completely eliminated.

Oxolinic ointment helps with herpes

The herpes virus affects 80% of the population. When the disease worsens, itching, burning, and pain are felt in the area of the rash; blisters appear, which subsequently burst, forming ulcers.

Therapy for herpetic rash is carried out with 3% ointment. Apply directly to the affected area 3-4 times a day. For mild forms of pathology, the course does not exceed 2 weeks. In case of a complicated course of the disease, oxolinic ointment is applied until the wounds are completely healed. If necessary, oral antiviral drugs are added.

Does oxolinic ointment help with chickenpox and lichen?

Treatment of chickenpox with oxolinic ointment is not welcomed by every pediatrician.

To treat chickenpox, 3% ointment should be used to treat skin rashes; if blisters and ulcers are localized on the mucous membrane, 0.25% ointment should be used.

Apply a thin layer 2-3 times a day to each element. The course of therapy is up to a week.

Oxolinic ointment prevents the spread of infection throughout the body and accelerates the healing of inflammatory elements.

When a diagnosis is made: herpes zoster or lichen simplex, the instructions for use correspond to the described actions for chickenpox.

Molluscum contagiosum and oxolin

Damage to the skin by the smallpox virus - molluscum contagiosum - is treated with oxolinic ointment. For treatment, 3% or 0.25% of the drug is used, depending on the location of the damaging element. If the mucous membrane is damaged, a less concentrated drug is used. The course of application is from 2 - 6 weeks to six months.

Contraindications for use

Treatment of pregnant and nursing mothers is possible only after consultation with a doctor; studies of the effect of oxolinic ointment during lactation have not been conducted.

In case of an allergic reaction to the components of the ointment, treatment with the drug is not permissible.

In addition, the development of adverse reactions may prohibit treatment with the drug:

• feeling of burning and irritation when applying the product;

• profuse nasal discharge (rhinorrhea) after applying the ointment;

• skin irritation - contact dermatitis.

If minor reactions to treatment develop, the question of further use should be considered by a doctor; in case of serious complications, the drug should be discontinued.

Analogs

There are no preparations containing oxolin, however, many antiviral agents in external and tablet forms have similar properties.

Preparations for external use:

• Acyclovir gel and ointment form;

• Vartek;

• Zovirax;

• Fenistil

• Lomargepan.

For a systemic effect on the virus, tablets and capsules are used:

• Arbidol;

• Amiksin;

• Kagocel;