pharmachologic effect
Persen Forte is a sedative medicine that is of plant origin.
Valerian extract contains a number of components that effectively act on the body during high nervous excitability and produce an antispasmodic and sedative effect.
Melissa extract also has an antispasmodic and calming effect, since they contain a number of essential oils, as well as glucosides, eflavonoids, monoterpenes, etc.
Peppermint has an antispasmodic effect on the smooth muscles of the digestive system, and also provides a carminative and choleretic effect. Mint contains essential oil, triterpene and phenolic acids, flavonoids.
Indications for use
Traditional medicine consists entirely of natural ingredients. The drug contains valerian root, mint and lemon balm leaves.
It has the following indications for use:
- Nervous conditions (neuroses), which are often accompanied by agitation, anxiety, and sleepless nights. However, these symptoms do not require the use of potent drugs;
- The period of time after stopping the use of potent drugs with a sedative effect;
- Hypertension and cardiac pathologies (tachycardia);
- Unreasonable restlessness and anxiety;
- Suppression of psychosomatic manifestations as a result of periodic stress.
Contraindications
It is contraindicated to take Persen Forte in the following cases:
- high sensitivity to any of the ingredients of this drug;
- fructose intolerance, deficiency of isomaltase and sucrase;
- lactose intolerance, lactase deficiency, glucose-galactose malabsorption;
- cholelithiasis , cholangitis , as well as other diseases of the biliary tract;
- arterial hypotension;
- period of pregnancy and breastfeeding;
- age up to 12 years.
People suffering from gastroesophageal reflux disease should take the capsules with caution.
Directions for use and doses
The instructions for use do not recommend giving Persen to children under 12 years of age, since there is no information on safety testing of the drug for this age group.
For persons over 12 years of age, the following dosage is recommended:
- For manifestations of irritability or increased nervous excitability, as well as under the influence of other negative factors - 3 tablets, 3 times a day, regardless of meal time;
- Persen Night for insomnia and other sleep disorders - 3 tablets 30 minutes before bedtime.
The medicine should be taken with warm water, regardless of the time of meal. The duration of treatment is determined by the doctor and depends on the patient’s condition and his personal tolerance to the drug. The recommended duration of use is at least two weeks and no more than two months. The daily dosage should not exceed 12 tablets.
Analogs
Level 4 ATC code matches: Alora
Motherwort extract
Novo-Passit
Cardiovalen
Liked
Carmolis
Valerian tincture
Lotusonic
Relaxil
Persen
Phytosed
Sedavit
Motherwort Forte Evalar
Dormiplant
Sondox
Sedafiton
Peony tincture
Menovalen
Bromcamphor
Valerian rhizomes with roots
Currently, there are no complete analogues of this medicine. Valdispert , Validol , Valeriana Forte , Glycine , Melison , Doppelhertz Nervotonic , Neurobutal , NovoPassit , etc. have a similar effect on the body
Compound
The composition of Persen and Persen Forte tablets is as follows:
- Dry valerian extract - 50 mg;
- Dry lemon balm extract - 25 mg;
- Dry peppermint extract – 25 mg.
Excipients: talc, magnesium stearate, crospovidone, corn starch, colloidal silicon dioxide, microcrystalline cellulose, lactose.
Use of the drug Persen
Indications
Persen, Persen Forte are prescribed for neuroses accompanied by the following symptoms:
- nervous excitement;
- anxiety;
- tension caused by stress;
- sleep disorders.
Persen cardio: temporary mild forms of mental stress, anxiety and excitability. Functional disorders of the heart and circulatory system associated with stress (for example, a feeling of increased heartbeat).
Persen Knight is prescribed as a sleeping pill.
Overdose
Symptoms A dose of about 20 g of valerian root, equivalent to approximately 103 tablets of Persen and 42 capsules of Persen Forte, may cause minor symptoms such as fatigue, cramps, chest tightness, dizziness, hand tremors, dilated pupils. these symptoms disappear within 24 hours. With an overdose of drugs containing valerian, headache, drowsiness, lethargy, general weakness, abdominal pain, nausea, decreased hearing and visual acuity, bradycardia/tachycardia, decreased concentration, increased sedation may also occur. effect.
There are no reports of cases of overdose of lemon balm leaves and peppermint.
Treatment is symptomatic (gastric lavage, taking activated charcoal).
Pharmacological properties
Pharmacodynamics.
Persen, Persen Forte are herbal preparations with a mild sedative effect. The combination of substances exhibits a weak sedative effect and is indicated for the elimination of mild transient nervous tension (as a daily sedative for mental stress, agitation, irritability).
Valerian has a sedative effect. It has a positive effect on well-being in cases of irritability symptoms such as restlessness, agitation and tension due to nervous overload. For insomnia, it helps you fall asleep faster. Melissa also has a sedative and antispasmodic effect.
Peppermint is traditionally used in combination with valerian in sedative preparations.
Persen, Persen forte are used for neuroses when taking potent sedatives is inappropriate. Indications for use are determined solely on the basis of long-term experience.
Persen Cardio is a herbal preparation with a mild sedative effect.
The drug contains dry extracts of passionflower herb and hawthorn leaves and flowers.
Preparations containing passionflower herb are used for temporary mental overload, agitation and insomnia.
Hawthorn leaf and flower extract increases cardiac conductivity, improves coronary blood flow and vascular circulation, prevents cardiac arrhythmia and moderately reduces blood pressure.
The effectiveness of the combination of these plants is based on their traditional use. The effects of medicinal plants are mutually complementary. The combination exhibits moderate sedative and cardiotonic activity.
Persen Knight. Valerian and passionflower roots have a calming effect in cases of minor anxiety and tension caused by moderate stress, and also make it easier to fall asleep.
Pharmacokinetics. No data.
Interactions
Data on interactions with other drugs are limited. Before using the drug simultaneously with other medications, you should consult your doctor.
No clinically significant interactions have been identified with active substances that are metabolized by CYP 2D6, CYP 3A4/5, CYP 1A2 or CYP 2E1.
Concomitant use with synthetic sedatives (benzodiazepines) is not recommended without consulting a doctor.
With simultaneous use, it is possible to enhance the effect of other sedatives and hypnotics, antispasmodics, analgesics, anxiolytic drugs, and alcohol.
Persen forte capsules No. 10x2
Name
Persen forte caps. in blister pack No. 10x2
Description
The capsules (body and cap) are red-brown in color, the contents of the capsule are brown granules with inclusions.
Main active ingredient
Valerian rhizome extract + lemon balm extract + mint extract
Release form
Capsules
Pharmacological properties
The drug has a calming and antispasmodic effect. Rhizome extract with valerian roots has a calming effect. Melissa leaf extract has a calming and antispasmodic effect. Peppermint leaf extract has an antispasmodic, moderate sedative effect.
Indications for use
In the complex treatment of mild functional disorders of the central nervous system (neurasthenia and sleep disorders). The use of the drug is based solely on the experience of traditional long-term use.
Directions for use and doses
Adults and children over 12 years old For increased nervous excitability, irritability - 2 capsules 2 times a day; for sleep disorders, it is recommended to take 1 capsule half an hour to 1 hour before bedtime. Capsules should be taken with a small amount of boiled water at room temperature (1/4 cup), regardless of meals. The effect of taking the drug Persen Forte develops gradually. To achieve optimal effect, it is recommended to take the drug for at least 14 days. The duration of the course of treatment is determined by the doctor taking into account the disease, tolerability of the drug and the achieved effect. If symptoms persist while taking the drug for fourteen days or the condition worsens, you should consult a doctor. Use in children Due to the lack of data on safety and effectiveness, the use of the drug Persen Forte by children under the age of 12 years is not recommended.
Use during pregnancy and lactation
Safety of use during pregnancy and lactation has not been established. Due to the lack of sufficient data, use during pregnancy and lactation is not recommended.
Precautionary measures
Patients with gastroesophageal reflux (heartburn) should avoid taking medications containing mint due to the potential for worsening heartburn. Patients with cholelithiasis or other diseases of the gallbladder and biliary tract should not take peppermint leaf preparations without medical supervision. One capsule contains 85.5 mg of lactose monohydrate and 35 mg of liquid glucose. Glucose levels must be taken into account in patients with diabetes. Due to the lactose monohydrate content, patients with galactose intolerance, lactase deficiency or glucose/galactose malabsorption syndrome should not take Persen Forte. Due to the glucose content, patients with glucose/galactose malabsorption syndrome should not take Persen forte. If symptoms persist while taking the drug or the condition worsens, you should consult a doctor.
Interaction with other drugs
Information on interactions between Persen and other medicinal products is limited. Before taking other medications, the patient should consult a doctor. Clinically significant interactions with substances that are metabolized by CYP 2D6, CYP 3A4/5, CYP 1A2 and CYP 2E1 were not observed. Concomitant use of the drug Persen with synthetic sedatives (for example, benzodiazepines) is not recommended and is allowed only under medical supervision.
Contraindications
Hypersensitivity to the components of the drug, children under 12 years of age, arterial hypotension, pregnancy, lactation.
Compound
One capsule contains: - 87.5 mg of dry hydroalcoholic extract of valerian roots (Valeriana officinalis L.) (4-7:1); extractant: ethanol 70% (v/v); — 17.5 mg dry extract of lemon balm leaves (Melissa officinalis L.) (3-6:1); extractant: ethanol 50% (v/v); — 17.5 mg of dry extract of peppermint leaves (Mentha piperita L.) (3-6:1); extractant: ethanol 40% (v/v). Excipients: lactose monohydrate, magnesium oxide, talc, maltodextrin, liquid glucose, powdered peppermint flavor, colloidal anhydrous silicon dioxide, magnesium stearate; titanium dioxide (E171), iron oxide yellow (E172); iron oxide red (E172), gelatin.
Overdose
A single dose of 20 g of rhizome extract with valerian roots (approximately 103 Persen tablets) can cause general weakness, spastic abdominal pain, chest tightness, dizziness, hand tremors and dilated pupils. If symptoms of overdose occur, consult a doctor. Treatment is symptomatic.
Side effect
The frequency of adverse reactions listed below: very often (≥1/10), often (≥1/100 to
Storage conditions
At a temperature not exceeding 25°C, out of the reach of children.
Buy Persen forte caps. in blister pack No. 10x2 in the pharmacy
Price for Persen forte caps. in blister pack No. 10x2
Instructions for use for Persen forte caps. in blister pack No. 10x2
Note!
Description of the drug Persen forte caps. No. 20 on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.
