De-Nol analogues: list of drugs where to buy at an affordable price

The drug "De-Nol" is used to treat ulcers and erosions of the digestive organs that form against the background of gastritis and other pathologies. The drug is expensive, but patients have the opportunity to buy similar drugs with the same or similar composition. The most popular medications are described below.

Brief description of the drug "De-Nol"

The drug "De-Nol" has an antiseptic astringent effect. It is used to treat ulcerative lesions of the digestive system. Available in tablet form, used orally. Admission is allowed to patients from 4 years of age.

The main active ingredient is the organic salt tripotassium bismuth dicitrate. Once in the stomach, it does not dissolve, but forms a protective film on the surface of ulcers and eroded areas. Thanks to this, the ulcers do not increase in size and gradually recover.

The product is effective and is good for treating ulcers. At the same time, it is produced in the Netherlands, so it is quite expensive (about 1000 rubles for a package of 112 tablets). Therefore, buyers are looking for more affordable analogues of both domestic and foreign production.

Discovery of Helicobacter pylori

The history of one of the greatest discoveries of the 20th century began in 1979, when ordinary doctor Barry Marshall received a position at the largest clinic in Western Australia - the Royal Perth Hospital. During one of the internal trainings organized by the clinic's management, Marshall met the talented pathologist Robin Warren. He was just studying the etiology of gastritis and managed to captivate his new friend. Already in 1981, the duo of Marshall and Warren discovered a spiral bacterium in the mucous membrane of patients with gastritis. It took researchers a year to develop a hypothesis linking the “newborn” Helicobacter pylori with strong ties to peptic ulcers and stomach cancer.

However, the road to success is rarely paved with roses and lilies. At first, the theory of Marshall and Warren met only grins from colleagues and skepticism from venerable scientists. In 1998, when the difficulties were over, Marshall wrote: “Everyone was against me then. But I knew I was right." Persistent Australians paved the way for their discovery, sparing neither time, nor strength, nor health.

After an unsuccessful attempt to infect piglets with Helicobacter pylori infection, Marshall decided on an experiment worthy of great researchers. He drank the contents of the Petri dish in which H. pylori was cultured and prepared to wait. The scientist hoped that in a year or a little more he would be diagnosed with a stomach ulcer, and he would finally prove an obvious cause-and-effect relationship. However, events were not long in coming.

Three days into the experiment, Marshall's mother noticed that her son's breath began to smell bad. Soon nausea and vomiting joined the symptoms, and just eight days after the desperate act, an endoscopic examination confirmed: acute gastritis had begun in the doctor’s stomach, and H. pylori was cultured from a smear of the mucous membrane. On the 14th day of the experiment, Marshall began taking antibiotics. After the course of treatment, complete recovery was recorded.

In 1985, details of the experiment appeared in the pages of the Medical Journal of Australia. By the way, this article soon gained worldwide fame and became the most cited in the entire history of the publication. It would seem that the evidence is obvious and the matter is small. However, full recognition was still almost a decade away.

Table 2.

Drugs for eradication therapy (international and trade names)

"Novobismol": analogue of "De-Nol"

The drug inhibits the bactericidal effect of Helicobacter - pathogenic microorganisms that lead to the development of gastritis. The active substance is the same component - tripotassium bismuth dicitrate. It acts as both an astringent and an anti-inflammatory agent.

The substance binds proteins that surround the affected parts of the stomach and intestines. They are covered with a protective film that stops the growth of the ulcer. The drug is domestically produced, you can buy it at a more affordable price of 700 rubles for a pack of 112 tablets.

The medicine is prescribed not only for ulcers, but for the treatment of such pathologies:

• gastritis (exacerbation stage);
• chronic gastroduodenitis;
• dyspepsia with functional disorder;
• irritable bowel syndrome.

The drug can be taken by patients over 4 years of age. Reception is carried out from 2 to 4 times a day while writing. In this case, the dosage and total duration of treatment is determined by the doctor. Typically the course lasts from 6 to 8 weeks.

Analogue of "De-Nol" drug "Venter": where to buy

Another Russian-made medicine. Used to treat gastritis and ulcerative lesions of the digestive system. It is also used for the prevention of erosions and ulcers, for the treatment of dyspepsia and gastritis in chronic form.

As part of complex treatment, it is used for gastritis with high acidity, gastrointestinal ulcers due to medications and digestive disorders. The medicine also gives good results in the treatment of reflux disease.

There are 2 active ingredients – sucrose sulfate and aluminum in the form of hydroxide. They interact with proteins and form a covering film on the affected area. It protects ulcers from further development and also serves as a preventive measure.

You can buy the product at a price of 450 rubles per pack of 50 tablets. Use it 2-4 tablets per day. Single dose – 1 pc. half an hour before meals. The specific dosage and duration of therapy are determined by the attending physician.

However, the described medicine has several contraindications:

• dysphagia;
• kidney function disorders;
• intestinal obstruction;
• internal bleeding in the intestines.

"Ventrisol"

Another inexpensive analogue of “De Nola”, which can be purchased at a price of 200 rubles per pack. The drug is produced in Poland, so its price is much lower. It is indicated for the treatment of ulcerative and erosive lesions of the digestive organs.

The active ingredient is bismuth, which promotes the formation of a coating film on the mucous membrane of the stomach or intestines. The drug is produced in the form of tablets that need to be taken orally half an hour before meals. In this case, the total duration of the course and the maximum dosage are determined by the attending physician.

Prices for the drug and its main analogues, average in Russia

The pharmacy chain offers a sufficient number of De-Nol analogues.
These are both domestic and foreign drugs. They all belong to the same group of drugs, but have minor differences in the mechanism of action and price. The cost of the most common analogues in Russian pharmacies:

Analogue of "De-Nol" medicine "Vitridinol"

This drug is produced in the form of tablets, which contain the same component - the organic salt tripotassium bismuth dicitrate. You can buy it in pharmacies at a price of 730 rubles for the largest package of tablets, 112 pcs. or for 350 rubles (60 pcs.).

The drug acts as an anti-inflammatory with an astringent effect. It is used as a treatment for ulcers and other mucosal lesions. Suitable for adults and children over 4 years of age. The standard dosage is 2 to 4 times a day, half an hour before meals. The course lasts for 4-8 weeks. Next, you need to take a break and continue therapy in consultation with your doctor.

"Ulkavis"

The drug contains the same active ingredient - tripotassium bismuth dicitrate. Available in tablet form. Forms a protective film based on organic and inorganic salts - bismuth citrate and oxychloride. It protects the gastric mucosa from the harmful effects of hydrochloric acid.

Reception is carried out according to similar rules - 1 tablet 2, 3 or 4 times a day 30 minutes before meals. Therapy lasts from 4 to 8 weeks. However, in the next 2 months it is not recommended to take products that also contain bismuth.

You can buy “Ulkavis” in pharmacies at an affordable price of 600 rubles for a pack of 112 tablets, 400 rubles for 56 pieces. and 200 rubles for 28 pcs. It is not necessary to present a prescription - the drug is sold freely.

Cheaper similar products

Due to the fairly high cost of the main product, patients sometimes have to look for cheaper analogues of De-Nol. However, these drugs cannot be called less effective. Some of them are quite capable of competing with expensive products.

Venter

Produced in Slovenia. The international nonproprietary name is Sucralfate, according to the active component of the drug. The drug does not have a systemic effect. The active substance accumulates in the stomach during treatment, interacting with the protein structures of the necrotic ulcer. In this way, a quick cure for gastric ulcers is achieved. 10-15% of sucralfate is excreted unchanged by the kidneys.

Venter

It is rarely used as an independent remedy in gastroenterology, mainly as part of complex therapy. The medication has virtually no contraindications, with the exception of individual intolerance to the active substance.

Vikalin

A combined drug that is used for ulcerative colitis and gastroesophageal reflux disease. The product contains bismuth nitrate, magnesium carbonate, sodium bicarbonate, calamus rhizome powder, kellin, rutin.

Action of Vikalin

It has classic astringent, enveloping and antacid effects. When applied, the tongue may turn black. The main feature of the medication is the incompatibility of the main substance with fermented milk products, which should be excluded during treatment.

Omeprazole

The drug based on the substance of the same name, omeprazole, is an H2 receptor antagonist. Country of origin: India. Available in the form of capsules consisting of two halves, white and pink. The capsule is coated with an enteric-soluble coating.

The product blocks the operation of the ion pump and minimizes the release of HCl in the stomach. Thanks to this, the factor that irritates the damaged epigastric mucosa is eliminated. Take 1 capsule 2 times a day for 2-4 weeks. It has virtually no contraindications. The manufacturer has no information about the occurrence of overdoses.

Lancerol

Production facilities are located in Ukraine. Lansoprazole capsules are white and gelatin-coated. Lancerol affects the release of hydrochloric acid. Main indications for use:

• stomach ulcer;
• erosive gastritis;
• stress ulcers.

Erosive gastritis

The drug has a small clinical base for use in different categories of patients, so its use in children and pregnant women is highly not recommended.