Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Intellan is a preparation containing plant components rich in active substances: alkaloids, flavonoids, glycosides, amino acids, saponins, vitamins and microelements. Stimulates metabolic processes in the brain and its activity, helps improve memory and attention. Improves blood circulation and supply of nutrients to the brain, promotes the removal of metabolic products. These effects are manifested by a decrease in general fatigue. Its neurostimulating effect is used in the treatment of depressive conditions.
Ginkgo biloba extract has a vasodilating effect and improves cerebral circulation, normalizes metabolic processes in tissues, prevents the formation of free radicals, and has an antihypoxic and pronounced decongestant effect.
Centella asiatica is called the “memory herb” because its main property is to improve blood circulation in the brain and supply it with oxygen. Has a calming effect on stress and anxiety. Improves mental activity, memory and thinking processes, increases learning ability. As a result of taking it, general well-being improves, fatigue is eliminated, and sleep improves.
Herpestis monniera contains amino acids and alkaloids that indirectly affect the synthesis of GABA in brain neurons. It has a stimulating, antioxidant and anticonvulsant effect.
Coriander has antioxidant, moderate hypotensive and anticonvulsant effects. It is also used to impart taste and smell to the drug.
Essential oils of Amomum subulate have a stimulating effect.
Emblica officinalis is rich in vitamins (C, B1, B2), microelements, phosphorus, iron, calcium. Its antioxidant effect is due to its high content of vitamin C. Thanks to the presence of pectins, it reduces cholesterol . Improves the function of the cardiovascular system.
Pharmacokinetics
Due to the complex, multicomponent composition, studying pharmacokinetics is impossible.
Intellan 90 ml syrup
Instructions for use of the drug for specialists INTELLAN Trade name INTELLAN International nonproprietary name No Dosage form Syrup Composition 10 ml of syrup contain thick extracts of: Ginko biloba leaves - 50.0 mg Centella of Asian grass - 100.0 mg Herpestis monniera grass - 10.0 mg Coriander sativum – 30.0 mg Amomum subulate fruit – 30.0 mg Emblica medicinal fruit – 40.0 mg excipients: sugar, anhydrous citric acid, glycerin, sodium methyl paraben, sodium propyl paraben, sweet orange essence, tutti-frutti essence , propylene glycol, distilled water. Description Brown syrupy liquid with a characteristic aromatic odor and a specific sour-sweet, bitter taste. Pharmacotherapeutic group Other drugs for the treatment of diseases of the nervous system. ATC code N07 Pharmacological properties Pharmacokinetics: The effect of the drug is the cumulative effect of its components; all the components together cannot be traced using markers or bioresearch, so kinetic observations are not possible. Pharmacokinetic studies were carried out only for individual bioactive components. Pharmacodynamics INTELLAN is the drug of choice among brain activity stimulants. Contains pharmacologically active plants that act as stimulating nerve-transmission substances. Ginko biloba – contains flavonol glycosides and terpene lactones. Improves cerebral circulation and supply of oxygen and glucose to the brain. It has a vasodilating effect and prevents platelet aggregation. Normalizes metabolic processes and has an antihypoxic effect on tissues. Prevents lipid peroxidation and the formation of free radicals in cell membranes. It has a pronounced anti-edematous effect on brain tissue and peripheral tissues. Centella asiatica – contains triterpene glycosides, bacosides, flavonoids. Improves capillary permeability in venous insufficiency. Herpestis monniera – contains alkaloids (brahmin, herpestine), glycosides, saponins, amino acids (aspartic, glutamic, serine, terionine, alanine, glycine, leucine). Has a stimulating, anticonvulsant effect. Coriander sativum - contains essential oil, borneol, thymol, camphene, betapinene, citronellol, nerol. It is used as a means of correcting taste and smell. Amomum subulate - contains essential oils (a-terpineol, myrcine, limonin, sabinin, b-felladrin, borneol). Has a stimulating effect. Emblica officinalis – contains a large amount of vitamin C, vitamins B1, B2, trace elements, calcium, phosphorus, iron, pectin. Reduces blood cholesterol levels with pectin. The high content of biologically active, natural, easily digestible vitamin C causes an antioxidant effect. Stimulates erythropoiesis, protein biosynthesis, promotes proper reproduction of tissues of mesenchymal origin - bone dentin and collagen. INTELLAN acts as a neurohumoral transmission modifier and has a stimulating effect on the metabolism of the cerebral cortex, stimulates brain activity and memory development. INTELLAN improves blood circulation in the brain, increases the supply of nutrition to nerve cells, and removes metabolic products. The mild neurostimulating effect reduces anxiety and helps in the treatment of subacute depressive conditions. Indications for use - cerebrovascular accidents - attention and (or) memory disorders - decreased intellectual abilities - asthenic conditions (psychogenic or neurotic) - overstrain and fatigue - neurosensory disorders (dizziness, tinnitus) - delayed mental and physical development of children - subacute depression and increased anxiety. Directions for use and dosage Adults – 2 teaspoons, 2 times a day. Children from 3 to 15 years old – 1 teaspoon 2 times a day. The drug is taken after meals. Side effects - possible allergic reaction to the components of the drug - sleep disturbance if the drug is taken at night Contraindications - increased individual sensitivity to the components of the drug - diabetes mellitus - exudative diathesis Drug interactions Not identified Special instructions The syrup contains sucrose, which must be taken into account by patients with diabetes mellitus, exudative diathesis, as well as with a hypocaloric diet. Use during pregnancy and lactation is not recommended, since there are no clinical data on the use of the drug during this period. Overdose Not identified Release form and packaging Syrup 90 ml in dark glass bottles, in cardboard packaging. Storage conditions Store at a temperature not exceeding +25ºС. Keep out of the reach of children! Shelf life: 3 years Do not use after the expiration date indicated on the package. Conditions for dispensing from pharmacies Without a prescription Manufacturer Herbion Pakistan Pvt Ltd 75400, Pakistan, Karachi Korangi Industrial Area, 30/28
Indications for use
- chronic stressful situations , overexertion and fatigue;
- cerebrovascular accidents;
- attention disorders, memory loss, forgetfulness;
- decreased intellectual capabilities;
- neurosensory disorders;
- subacute depressive states (in the form of auxiliary treatment);
- increased anxiety ;
- astheno-neurotic conditions in somatic diseases .
Instructions for use of Intellan (Method and dosage)
Capsules and syrup are taken orally. Dose for adults - 1 capsule or 2 tsp. syrup 2 times a day after meals. In the evening, take capsules or syrup 3-4 hours before bedtime. Duration of treatment is from 1 to 3 months. The course can be repeated after a 3-week break.
Intellan syrup is preferable for children from 3 to 15 years old, it is prescribed 1 tsp. 2 times a day.
The instructions for use of Intellan contain a warning that the syrup contains sucrose , so it should not be taken by patients with diabetes .
special instructions
The drug contains sucrose, which should be taken into account by patients with diabetes mellitus, as well as people on a low-calorie diet.
Use during pregnancy and lactation. The use of the drug during pregnancy or breastfeeding is not recommended.
The ability to influence reaction speed when driving vehicles or working with other mechanisms. Taking the drug affects the reaction rate when driving vehicles or working with other mechanisms (possible decrease in attention), so you should avoid driving vehicles or working with other mechanisms.
Children. The drug is not prescribed to children under 2 years of age.
Analogs
Level 4 ATX code matches:
Ginos
Akatinol Memantine
Tanakan
Noodzheron
Ginkgo biloba
Bilobil
Memantine
Memoplant
Ginkum
Vitrum Memory
Namenda
There are no structural analogues. Preparations containing ginkgo biloba : Ginos , Bilobil , Memoplant , Tanakan , Gingium .
Reviews about Intellan
Analyzing reviews of Intellan, we can conclude that the drug is used not only to treat adults, but also children with functional and organic lesions of the central nervous system. It is prescribed to children, starting from 2 years of age, with psycho-speech-motor developmental delay. Taking the drug improved psycho-speech development: speech, auditory perception and cognitive activity of children improved. Fine motor skills have also improved.
There is no addiction to the drug, so it can be taken for a long time as prescribed by a doctor.
“I’m giving the child Intellan for the second year. The drug helps, the benefits for the child are tangible.”
“We took the course for 3 months. Very good results: my thinking has improved, I began to invent, compose and reflect a lot.”
“We are taking Intellan for the second time, a course of 2 months. We are pleased with the results."
“We’ve only been drinking for a week, but the child has perked up and is trying to repeat words.”
Many people note excessive excitability and sleep disturbance in adults and children if the drug is taken at night. In isolated cases, stool upset was observed after taking the drug.
Note!
Description of the drug Intellan syrup fl. 120ml on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.
Intellan price, where to buy
You can buy it in many pharmacies in Moscow and other Russian cities. The price of Intellan in capsules No. 20 is 185 - 227 rubles. Intellan syrup is currently not available in the pharmacy chain.
- Online pharmacies in RussiaRussia
- Online pharmacies in KazakhstanKazakhstan
LuxPharma* special offer
- Intellan syrup bottle 120ml
RUR 1,880 order
ZdravCity
- Intellan capsules 20 pcs.Herbion Pakistan (PVT) Ltd
RUB 238 order
- Intellan syrup 90mlHerbion Pakistan PVT Ltd
RUB 192 order
Pharmacy Dialogue
- Intellan capsules No. 20Herbion
RUB 183 order
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