Vizarsin: instructions for use, reviews from men, how long does the tablet last?

Composition and pharmacological action of Vizarsin

The active component of the drug is sildenafil citrate. Additionally, the medication contains form- and volume-forming substances.

Auxiliary connections are:

• microcrystalline cellulose – Avicel RN102;
• calcium dihydrogen phosphate;
• microcrystalline cellulose - Avicel PH101;
• croscarmellose sodium;
• magnesium stearate;
• hypromellose.

The film shell contains titanium dioxide, lactose monohydrate, triacetin and hypromellose as components.

The active component, being a strong selective inhibitor of cGMP-specific phosphodiesterase type 5, has a powerful vasodilating effect and restores erectile function.

The mechanism of action of sildenafil is due to the release of NO in the corpus cavernosum. During sexual stimulation, which leads to an increase in cGMP levels with subsequent relaxation of the smooth muscle tissue of the corpus cavernosum, blood flow to it increases. For the development of the therapeutic effect of sildenafil and the onset of erection, sexual stimulation is necessary.

After taking the Vizarsin tablet orally, the active substance is absorbed from the gastrointestinal tract into the blood within 20-30 minutes. The maximum concentration is reached after 60 minutes.

Metabolization of the compound is carried out by liver tissue cells with the formation of breakdown products, which are mostly excreted from the body with feces and partly by the kidneys in urine.

pros

• High efficiency of the drug
• Possibility of obtaining a rapid therapeutic effect
• Convenient dosage form of the drug
• The product has a fairly affordable price compared to analogues

Minuses

• Dispensing medication according to a doctor's prescription
• The presence of a large number of contraindications and side effects
• High likelihood of side effects and adverse reactions
• The presence of side effects that prevent you from driving a vehicle
• May interact with many medications
• Incompatible with drinking alcoholic beverages

Consequences of an overdose of Vizarsin

In case of an overdose of Vizarsin, various symptoms characteristic of this drug, associated with its mechanism of action, may be observed. consequences may occur :

• collapse (acute disruption of the blood supply to vital organs);
• deafness;
• retinal damage or blindness;
• damage to the penis due to prolonged erection;
• heart attack (myocardial infarction).

To avoid the above health effects, you should always consult a medical professional before taking Visarsin. You also need to follow all the doctor’s instructions and read the instructions for the drug.

Instructions for use of the drug

Before using the drug, it is advisable to consult a urologist or sexologist to find out the causes of erectile dysfunction.

The instructions for use of Vizarsin recommend using only as prescribed by the attending physician and in strict accordance with his recommendations. Independent use of the drug for self-medication is strictly prohibited.

Indications for use

According to the instructions, Visarsin is recommended to be prescribed for drug correction of erectile dysfunction, which is characterized by the inability to achieve or maintain an erection of the penis sufficient for full sexual intercourse.

Method of use

The Vizarsin tablet is taken orally, as a whole. It is advisable to take on an empty stomach, as in this case the absorption of the active substance increases. After taking the drug, it is recommended to take the tablet with a sufficient amount of liquid.

In accordance with the annotation for the drug, the recommended dosage is 50 mg once a day. A larger number of doses of the drug is not permissible. If necessary, the daily dose can be increased to 100 mg, which are also taken at a time. To obtain a sufficient therapeutic effect, sexual stimulation is necessary, otherwise an erection will not develop.

When conducting therapy in elderly patients, no adjustment of the recommended dose is required. If the patient has pathologies in the liver and kidneys, the dosage is reduced to 25 mg per day.

Contraindications of the drug

When using Vizarsin for drug therapy, it is necessary to take into account the possible presence of contraindications for the patient.

The use of tablets is contraindicated in certain pathological and physiological conditions of the body.

It is prohibited to use the drug for:

1. Individual hypersensitivity or intolerance to sildenafil or auxiliary components of the tablets.
2. Simultaneous use of Vizarsin with drugs that act as nitric oxide donors or nitrates. This combination provokes a pronounced decrease in blood pressure.
3. The presence of pathology of the retina, which is manifested by its ischemia due to disruption of blood supply processes.
4. Arterial hypotension.
5. Brain stroke and myocardial infarction.
6. Coronary heart disease, severe atherosclerosis, hypertension, when taking the drug and sexual activity increase the risk of developing a vascular accident.
7. Any pathology of the liver, accompanied by its severe functional failure.
8. Congenital angiopathy.
9. Under 18 years of age.

The medicine is also not used for women. Before prescribing the drug, you must ensure that there are no contraindications to its use.

Side effects

In the process of drug therapy, the patient may develop undesirable reactions from various organs and their systems.

Side effects of therapy are:

• attacks of nausea and vomiting, dry mouth, dyspepsia, manifested by bloating and unstable stools;
• a feeling of flushing in the face, less often an increase in the number of heart contractions with a corresponding sensation of palpitations, pressing pain in the heart area due to insufficient blood supply to the myocardium;
• priapism;
• blurred vision, transient changes in color perception, narrowing of visual fields, circulatory disorders of the retina, tinnitus;
• headache, attacks of dizziness, drowsiness during the day, insomnia at night, in rare cases, fainting, transient ischemic attack;
• runny nose, feeling of nasal congestion, in rare cases, nosebleeds;
• muscle pain;
• allergic reactions in the form of a skin rash, itching, a characteristic rash and swelling of the skin, reminiscent of a nettle burn.

When the first signs of side effects or adverse reactions are detected in the patient, the drug is stopped.

If the recommended dosage is exceeded, the patient experiences characteristic symptoms.

An overdose of the drug is manifested:

1. nausea;
2. vomiting;
3. dizziness;
4. flushes of blood to the skin of the face;
5. nasal congestion;
6. dysfunctions of the visual organs.

To eliminate the consequences of the harmful effects of an overdose, gastric and intestinal lavage is used, as well as methods of symptomatic therapy. The use of hemodialysis is ineffective.

What you need to know before you start taking Vizarsin

Do not take Vizarsin if you have an allergic reaction to it or if you are taking medications to treat pulmonary hypertension (for example, Adempas is an antihypertensive drug that stimulates the enzyme guanylate cyclase).

You should also not take Vizarsin if you are taking nitrate drugs (for example, nitroglycerin, isosorbide dinitrate) to treat heart pain, since the mechanism of action of the latter is also associated with the release of the NO factor. As a result of this combined interaction, vasodilation may increase and this will lead to a sharp drop in blood pressure with possible loss of consciousness.

Before taking Vizarsin, you should consult a doctor to take your medical history to make sure you do not have conditions such as:

• problems with the cardiovascular system (arrhythmia, arterial hypo- or hypertension);
• problems with blood circulation;
• retinitis pigmentosa (hereditary eye disease);
• visual impairment;
• blood diseases (for example, anemia, leukemia);
• pulmonary veno-occlusive disease (complications of pulmonary hypertension, which affects small pulmonary veins);
• liver and/or kidney diseases;
• physical deformation of the penis (for example, Peyronie's disease).

This medicine is only for men.

Vizarsin is approved for use from 18 years of age.

Drug interactions and special instructions

When using Vizarsin in combination with other drugs, the compatibility of the drugs should be taken into account.

When prescribing the drug with:

• inhibitors of cytochrome P450 isoenzymes - CYP3A4 may reduce drug clearance;
• Ritonavir increases the concentration of sildenafil in plasma by an order of magnitude;
• with grapefruit juice a moderate increase in the plasma concentration of Vizarsin is recorded;
• There are no changes in the bioavailability of the drug with antacids;
• inhibitors of the isoenzyme CYP2C9, CYP2D6, thiazide and similar diuretics, potassium-sparing and loop diuretics, angiotensin-converting enzyme inhibitors, calcium channel blockers, beta-blockers, inducers of the CYP450 isoenzyme do not affect the pharmacokinetics of sildenafil;
• Nicorandil may experience undesirable interactions with the drug due to the presence of a nitrate component in the composition;
• donors of nitric oxide, nitrates in any dosage form have a negative effect in the form of an increase in the hypotensive effect;
• alpha-blockers may cause symptomatic hypotension in susceptible patients.

The drug is prescribed only after a clinical examination to diagnose and identify possible causes of decreased potency. The state of the cardiovascular system is also assessed, since sexual activity in the presence of pathologies in the functioning of the heart and blood vessels may pose a certain risk.

The systemic vasodilating effect of sildenafil causes a slight transient decrease in blood pressure, so patients with relevant pathologies should take into account the risk of developing possible undesirable vasodilatory effects against the background of sexual activity before taking Visarsin.

The use of Vizarsin in combination with other drugs for the treatment of erectile dysfunction is not recommended. Caution should be exercised in patients with anatomical deformation of the genital organ.

Visual disturbances are possible during the use of Vizarsin. Due to the possible development of dizziness and visual impairment, caution should be exercised when operating machinery or vehicles.

For active peptic ulcers or bleeding, the potential risks and expected benefits of using the drug should be weighed before starting therapy.

Taking the drug is incompatible with drinking alcohol; therefore, it is recommended to abstain from alcoholic beverages throughout the entire period of drug therapy.

Symptoms of Vizarsin overdose

When taking Vizarsin in the above prescribed dosages prescribed by a doctor, or in a dose exceeding the daily dose, symptoms of an overdose of this medicine may be observed:

• chest pain, which can radiate (give) to other parts of the body;
• dyspnea;
• painful erection that does not go away for more than 4 hours;
• tinnitus;
• interruptions in heart rhythm;
• orthostatic hypotension (a sharp drop in blood pressure);
• visual impairment.

If you observe such symptoms, you must stop subsequent use of Vizarsin and seek help from a specialist.

Reviews about Vizarsin

Vizarsin, according to reviews from men who used it to improve potency, is an excellent drug. Positive feedback about the effect of the drug is left not only by men, but also by their sexual partners.

Patient review

The drug can really significantly improve erection. Patients testify that the medication begins to exhibit its therapeutic effect within an hour after taking it and helps ensure a stable and long-lasting erection, which is necessary for full sexual intercourse.

The vast majority of patients recommend that before using the medicine, consult a doctor about its use, which is due to the presence of quite serious contraindications for the medicine and a high probability of developing side effects and unwanted reactions.

As advantages of the drug, users cite its affordable cost compared to, for example, Viagra and the possibility of obtaining a quick therapeutic effect.

Many men consider the disadvantage that the drug has a large number of contraindications and side effects, as well as the possibility of purchasing the drug only with a prescription from the attending physician.

What are the side effects of Vizarsin?

Common side effects from Visarsin include:

• dizziness, headache, fog;
• heartburn, nausea, indigestion;
• abnormal vision (blurry vision, changes in color vision)
• runny nose and/or nasal congestion, nosebleeds;
• problems sleeping (insomnia);
• muscle pain, back pain.

If you experience any of the following conditions after taking Visarsin, you should immediately seek medical help :

• pressing pain in the heart, which can radiate to the arm, shoulder, jaw;
• hard breath;
• changes in vision or sudden loss of vision;
• painful erection that lasts more than 4 hours (prolonged erection can damage the penis);
• ringing in the ears or sudden hearing loss;
• arrhythmia (pulse changes);
• swelling of the arms, ankles, or feet;
• convulsions;
• feeling like you might lose consciousness.

Analogues of the drug

If side effects occur during the use of Visarsin or if the patient has contraindications to its use, the doctor may suggest the use of drug analogues that have a similar therapeutic effect on the body.

Common substitutes are:

1. Sildenafil is a drug for the treatment of erectile dysfunction. The medication is available in the form of film-coated tablets with a biconvex, diamond-shaped shape. The medicine has a blue outer color and a white inner color. The active compound in the medication is sildenafil citrate. Microcrystalline cellulose, anhydrous calcium hydrogen phosphate, croscarmellose sodium, magnesium stearate, opadry II blue and opadry transparent are used as auxiliary components. The shelf life of the drug is 3 years. The medicine must be stored at a temperature not exceeding 25 degrees Celsius. Dispensing is carried out by prescription. The cost of the medicine is about 530 rubles per package, which contains 10 tablets.
2. Maxigra is a drug used in the treatment of erectile dysfunction. Available in tablet form. The active ingredient is sildenafil. Excipients include sodium lauryl sulfate, colloidal silicon dioxide, magnesium stearate, mannitol, corn starch, crospovidone and povidone. The medicine is available by prescription. The shelf life is 4 years. The medication should be stored at a temperature not exceeding 30 degrees. The price of the drug in pharmacies ranges from 297 to 774 rubles, depending on the dosage and number of tablets in the package.

Additionally, Viagra, Dynamico and Cialis can be used as substitutes with similar effects.