Pharmacodynamics and pharmacokinetics
Breast Elixir is a combined action expectorant, the effectiveness of which is due to the action of its active ingredients.
Thick licorice extract is characterized by its expectorant and anti-inflammatory effects, due to the presence of glycyrrhizin , which has a stimulating effect in the bronchi and trachea on the function of ciliated epithelial , as well as increasing the secretion of the mucous membrane of the upper respiratory tract.
The irritating effect of an aqueous solution of ammonia in the upper respiratory tract triggers the excitatory mechanisms of sensitive nerve cells and reflex stimulation of the respiratory center .
Thanks to anethole , contained in anise oil , its expectorant effect is manifested, as well as the effects of reflex stimulation of breathing , increased activity of ciliated epithelial and increased secretion of the mucous membrane of the trachea , larynx and bronchi .
Compound
Elixir | 100 ml |
active substances: | |
licorice extract thick | 20.7 g |
(with glycyrrhizic acid content 14%) | |
anise oil | 0.34 g |
ammonia solution concentrated 25% | 1.38 g |
(equivalent to 0.345 g of ammonia) | |
excipients: ethyl alcohol (ethanol) 90% - 20.41 ml; purified water - up to 100 ml |
Analogs
Level 4 ATX code matches:
Cashnol
Anise oil
Bronchophyte
Pine buds
Pertussin
Bronchosan
Gedelix
Mixture for inhalation
Herbion ivy syrup
Herbion plantain syrup
Herbion primrose syrup
Mukaltin
Sinupret Forte
Dr. Theiss syrup with plantain
Bronchosept
Joset
Thermopsol
Tussamag
Marshmallow syrup
Dry cough syrup
- Marshmallow syrup;
- Bronchicum;
- Gedelix;
- Bronchipret;
- Gerbion;
- Doctor Mom;
- Chest collection;
- Linkas;
- Mukaltin;
- Pertussin;
- overslept;
- Licorice syrup;
- Eucabalus , etc.
special instructions
The drug contains 90% ethyl alcohol. The content of absolute ethyl alcohol in one drop of the drug is 0.0075 g, in the maximum single dose for adults - up to 0.3 g, in the maximum daily dose - up to 1.2 g.
Impact on the ability to drive vehicles and engage in other potentially hazardous activities. During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
Pharmacological properties:
The expectorant effect of the breast elixir is due to the action of its constituent components:
— thick licorice extract has anti-inflammatory and expectorant properties, which are associated with the content of glycyrrhizin in the roots, which stimulates the activity of the ciliated epithelium in the trachea and bronchi, as well as enhancing the secretory function of the mucous membranes of the upper respiratory tract;
— anise oil has an expectorant effect due to the content of anethole in the oil, which promotes reflex stimulation of breathing, increased activity of the ciliated epithelium of the respiratory tract and increased secretion of the mucous membranes of the larynx, trachea and bronchi;
- ammonia has an irritating effect, which leads to excitation of the endings of the sensory nerves of the upper respiratory tract and reflex stimulation of the respiratory center.
Pharmacokinetics. No data available.
Package:
25 ml
Indications for use:
As an expectorant for infectious and inflammatory diseases of the respiratory tract, accompanied by a cough with difficult to separate sputum (including tracheitis, tracheobronchitis, bronchitis).
Contraindications:
Hypersensitivity to the components of the drug, bronchial asthma, gastritis, peptic ulcer of the stomach and duodenum during exacerbation, pregnancy, breastfeeding. With caution: Liver disease, alcoholism, traumatic brain injury, brain disease, childhood.
Directions for use and dosage:
Orally 3-4 times a day. Adults take 20-40 drops; children are prescribed as many drops as the child’s age. Before use, it should be diluted in a small amount of water.
,The course of treatment is 7-10 days. Increasing the duration and conducting repeated courses of treatment is possible on the recommendation of a doctor.
Side effects:
Allergic reactions are possible, and in some cases diarrhea may occur.
Overdose:
With long-term use in excess of the specified dosages, hypokalemia, increased blood pressure, and the appearance of peripheral edema are possible due to impaired water-salt metabolism.
Treatment: symptomatic.
Interaction with drugs:
If necessary, can be used in combination with antibiotics and other drugs. It should not be used simultaneously with antitussive drugs, as this makes it difficult to cough up liquefied sputum.
Special instructions:
The drug contains 90% ethyl alcohol. The content of absolute ethyl alcohol in one drop is 0.0075 g, in the maximum single dose for adults - up to 0.3 g, in the maximum daily dose - up to 1.2 g.
During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
Release form:
Elixir.
25 ml in orange glass bottles, sealed with polyethylene stoppers; plastic screw-on caps and caps made of polymer materials.
Each bottle, along with instructions for medical use, is placed in a cardboard pack.
The text of the instructions for medical use is allowed to be applied to the cardboard box.
25 ml bottles with the appropriate number of instructions for medical use are placed in group containers.
Labels made of label or writing paper or a self-adhesive label are glued onto bottles and canisters.
Storage conditions:
At a temperature not higher than 20 ºС. Keep out of the reach of children.
Best before date:
3 years. Do not use after the expiration date stated on the package.
Conditions for dispensing from pharmacies:
Over the counter.
Manufacturer/Organization accepting complaints
JSC "Kirov Pharmaceutical Factory" Russia, 610000, Kirov, st. Moskovskaya, 27 a Tel./fax, 65-35-10 E-mail www.k-ff.ru
Breast Elixir
Dosage form
Oral solution.
Compound
Active ingredients:
Licorice root extract (Licorice extract thick)
with glycyrrhizic acid content 14% – 20.7 g
Anise fruit oil (Anise oil) – 0.34 g
Concentrated ammonia aqueous 25% [equiv. 345 mg ammonia] – 1.38 g
Excipients
:
Ethanol (ethyl alcohol) 90% – 20.41 ml,
Purified water – up to 100 ml.
Description
Brown liquid with a characteristic odor. Precipitation may occur during storage.
Pharmacotherapeutic group
Expectorant of plant origin.
ATX code : R05CA10
pharmachologic effect
The expectorant effect of the breast elixir is due to the action of its constituent components:
— thick licorice extract has anti-inflammatory and expectorant properties, which are associated with the content of glycyrrhizin in the roots, which stimulates the activity of the ciliated epithelium in the trachea and bronchi, as well as enhancing the secretory function of the mucous membranes of the upper respiratory tract;
— anise oil has an expectorant effect due to the content of anethole in the oil, which promotes reflex stimulation of breathing, increased activity of the ciliated epithelium of the respiratory tract and increased secretion of the mucous membranes of the larynx, trachea, and bronchi;
- ammonia has an irritating effect, which leads to excitation of the endings of the sensory nerves of the upper respiratory tract and reflex stimulation of the respiratory center.
Indications for use
As an expectorant for infectious and inflammatory diseases of the respiratory tract, accompanied by the formation of difficult to separate sputum (including tracheitis, tracheobronchitis, bronchitis).
Contraindications
Hypersensitivity to the components of the drug, bronchial asthma, gastritis, peptic ulcer of the stomach and duodenum during exacerbation, pregnancy, breastfeeding.
Carefully
Liver diseases, alcoholism, traumatic brain injury, brain diseases, childhood.
Use during pregnancy and breastfeeding
Contraindicated for use during pregnancy and breastfeeding.
Directions for use and doses
Inside, 3-4 times a day. Adults – 20-40 drops; Children are prescribed as many drops per dose as the child is old. Before using the drug, it should be diluted in a small amount of water.
The course of treatment is 7 days. Increasing the duration and conducting repeated courses of treatment is possible on the recommendation of a doctor.
Side effect
Allergic reactions are possible, and in some cases diarrhea may occur.
If side effects not described in these instructions occur, you should stop taking the drug and inform your doctor.
Overdose
With prolonged use in excess of the indicated dosages, hypokalemia is possible. increased blood pressure, the appearance of peripheral edema due to impaired water-salt metabolism.
Treatment: symptomatic.
Interaction with other drugs
If necessary, can be used in combination with antibiotics and other drugs. It should not be used simultaneously with antitussive drugs, as this makes it difficult to cough up liquefied sputum.
special instructions
The content of absolute ethyl alcohol in 1 drop of the drug is 0.0075 g, in the maximum single dose for adults - up to 0.3 g, in the maximum daily dose - up to 1.2 g. During the treatment period, care must be taken when driving vehicles and doing activities other potentially dangerous activities that require increased concentration and speed of psychomotor reactions.
Release form
Elixir. 25 ml of the drug in orange glass bottles with a screw neck, sealed with polyethylene stoppers and screw caps.
Each bottle with instructions for use is placed in a cardboard pack.
It is allowed to pack bottles together with an equal number of instructions for use in a group packaging made of cardboard.
Storage conditions
At temperatures from 15 to 25 oC.
Keep out of the reach of children.
Best before date
3 years.
Do not use after the expiration date.
Vacation conditions
Available without a prescription.