Instructions for use TABEX

pharmachologic effect

The drug is an N-cholinomimetic. It has an exciting effect on the nicotinic receptors of the autonomic ganglia, has a reflex stimulating effect on the respiratory center, promotes the release of adrenaline , and increases blood pressure .

As a result, Tabex effectively reduces the body's dependence on nicotine . Under the influence of the drug, the taste of smoking becomes unpleasant for a person. Gradually the desire to smoke decreases. The drug helps reduce withdrawal syndrome , which is associated with quitting nicotine.

In general, the effect of cytisine is close to the mechanism of action of nicotine. This allows you to gradually stop smoking and significantly reduce the intensity of withdrawal symptoms.

Analogues and interaction

The drug has no analogues for the active substance; there are only other means intended to facilitate smoking cessation:

As the patient stops the bad habit, the negative effects from taking Clozapine and Theophylline may increase. If, in parallel with tobacco smoking therapy, treatment with cholinomimetics (bromides) is prescribed, there is a high risk of the following symptoms:

• profuse lacrimation;
• increased saliva production;
• cough with sputum production;
• asthmatic attacks;
• constriction of the pupils;
• intestinal and biliary colic;

• vomit;
• increased urine output;
• muscle hypertonicity;
• involuntary contraction of muscle tissue.

It is also undesirable to use the medicine during treatment with statins (drugs for high cholesterol). Such therapy often causes severe muscle pain - myalgia. Tabex reduces the effectiveness of taking antihypertensive drugs, which should be taken into account in the presence of high blood pressure.

Pharmacodynamics and pharmacokinetics

The pharmacokinetics of Tabex have not been studied in humans. Wikipedia indicates that data on the pharmacokinetics of the drug appeared as a result of animal studies. The substance Cytisine is absorbed from the gastrointestinal tract quickly, but not completely. In mice, after oral administration of the drug, the degree of resorption is 42%, in rabbits - 34%. When administered orally, the highest concentration in mice was achieved after 2 hours, in rabbits - after 35 minutes. The maximum plasma concentration of cytisine is observed in the kidneys , liver , and adrenal glands .

The half-life of the drug taken intravenously in mice is 200 minutes, 18% of the dose taken orally was eliminated in mice over 24 hours. In rabbits, the half-life after intravenous administration is 37 minutes.

Tabex contains cytisine , the effect of which on the body is similar to that of nicotine.

Contraindications for Tabex

The drug should not be taken by those who have hypersensitivity to cytisine or other components of this drug. Contraindications to Tabex are observed in those people who suffer from certain physical and mental illnesses. In particular, contraindications for smoking pills are observed in the following diseases:

• acute form of myocardial infarction ;
• arrhythmias;
• angina pectoris;
• circulatory disorders in the brain;
• bleeding from large vessels;
• atherosclerosis;
• arterial hypertension;
• exacerbation of duodenal and gastric ulcers ;
• pulmonary edema;
• bronchial asthma.

Doctors prescribe Tabex and its analogues with caution to patients with schizophrenia , coronary heart disease , diabetes mellitus , chromaffin tumors of the adrenal glands , gastroesophageal disease , hyperthyroidism , as well as patients with renal and liver failure .

For children and people over 65 years of age, the drug is prescribed only after assessing how the benefits and potential risks compare.

Special instructions for the use of Tabex

The use of the drug and simultaneous smoking can lead to increased side effects of nicotine (nicotine intoxication). Tabex should be prescribed only when the patient has a serious intention to quit smoking. There is not enough clinical experience with the use of Tabex in patients with coronary artery disease, heart failure, hypertension (arterial hypertension), cerebrovascular diseases, obliterating arterial diseases, hyperthyroidism, peptic ulcers, diabetes mellitus, renal or liver failure. For these categories of patients, the drug should be prescribed only after a careful assessment by the physician of the benefit/risk ratio. Children under 18 years of age and adults over 65 years of age should use the drug with caution after careful assessment of the benefit/risk ratio. Considering the possible occurrence of dizziness, tremor, and irritation, you should be careful when driving vehicles and working with precision mechanisms. With each dose, up to 0.028 g of sugar enters the body. This is dangerous for people with lactose intolerance, galactosemia or glucose/galactose malabsorption syndrome.

Side effects of Tabex

Side effects of tablets can occur in a number of body systems. Reviews of the side effects of the drug indicate that the drug may have the following side effects:

• a feeling of dry mouth , diarrhea , constipation , nausea , changes in taste and fluctuations in appetite - from the digestive system;
• dizziness and headaches , drowsiness or insomnia , periodic increase in irritability - from the nervous system;
• tachycardia , increased blood pressure, shortness of breath , pain in the chest - from the cardiovascular system.

In addition, there may be a decrease in body weight , myalgia , high sweating , and allergic manifestations.

As a rule, side effects disappear on their own. If the side effects of Tabex worsen, you should definitely consult a specialist.

Special conditions

Treatment with Tabex is prescribed with caution if a man or woman has a very long history of smoking, as well as over the age of 45 years. In this case, you cannot use the drug yourself; you must obtain medical advice and prescription.

It is very important to reduce the number of cigarettes during therapy, otherwise the danger of nicotine intoxication is high.

Due to the nature of its action, the drug can increase nicotine poisoning in the body if a person takes Tabex but does not quit smoking.

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When taking it, it is necessary to take into account that the tablets contain lactose, so if there are hereditary and acquired pathologies associated with a violation of its processing, you will have to choose a different drug. Tabex can also cause harm in cases of galactose intolerance and glucose-galactose malabsorption. Due to possible headaches and drowsiness, caution should be exercised when driving or performing other hazardous activities.

Instructions for use of Tabex (Method and dosage)

The instructions for Tabex suggest a specific method of using the tablets. Initially, 1 tablet is prescribed five times a day, later the dose should be reduced to 1-2 tablets per day. Treatment with this drug lasts from 20 to 25 days. The method of using Tabex must be approved by a doctor in each individual case. It is advisable to find out in more detail how to take Tabex from the specialist who prescribes the treatment. If the patient continues to take the pills correctly, but there is no effect, it is necessary to undergo treatment again after 2-3 months.

When advising the patient how to take the pills, the doctor also warns that smoking must be completely stopped no later than five days after the start of treatment.

Overdose

In case of overdose, a person may experience the following symptoms:

• nausea and vomiting ;
• convulsions;
• general feeling of weakness;
• tachycardia , increased heart rate ;
• respiratory paralysis.

If such symptoms appear, it is necessary to completely stop treatment with the drug.

Patients trying to quit smoking with the help of this drug, and who have exceeded the dose of taking it, need to rinse the stomach, if necessary, administer infusion solutions , drugs against seizures and other drugs that relieve symptoms. It is important to closely monitor your heart rate and blood pressure.

Analogs

Level 4 ATX code matches:
Cititon

Champix

Nicorette

Analogues of the drug are products in which the active ingredient is cytisine. Such products are produced in the form of tablets ( cytiton , cytisine , lobesil ), in the form of special films that are glued to the skin ( cypercuten ).

Which is better Brizantine or Tabex?

There are a number of drugs that have an effect on the smoker’s body similar to Tabex. These are Brizantine , Nicorette , Champix , etc. The drug Brizantine contains antibodies to brain-specific proteins, which helps reduce a person’s craving for nicotine. However, which is better, Brizantine or Tabex, can only be determined after an individual consultation with a doctor. The cost of the drug in Moscow is 280 rubles.

Nicorette or Tabex - which is better?

Nicorette contains nicotine, so it is used as replacement therapy in the process of quitting smoking tobacco . Nicorette comes in the form of chewing gum, so the nicotine is released and absorbed into the body gradually. The cost of the drug in the form of chewing gum in Ukraine ranges from 75 to 88 UAH.

Which is better Champix or Tabex?

The drug Champix contains varenicline , which interacts with nicotinic acetylcholine receptors. As a result, the severity of withdrawal syndrome decreases. There are different opinions about whether this drug helps you quit smoking. But its cost is higher than Tabex: in Ukraine it ranges from 335 to 336 UAH. You can find out whether pills help you quit smoking from the reviews of those who have undergone such treatment.

Indications and contraindications

The main indication for taking pills is the presence of nicotine addiction. The drug does not eliminate the need for treatment of psychological addiction, it only facilitates the physical cessation of smoking. This remedy is especially indicated for long-term smoking and the inability to quit cigarettes without medication.

The drug has a number of important contraindications, including age - it is forbidden to drink it before the age of 18 and over 65 years.

Tabex should not be taken if you are intolerant to any component or have an allergic reaction to any of the constituent substances. It is prohibited in severe forms of heart disease - a previous heart attack, advanced angina or its unstable type, and arrhythmias. Tabex is prohibited for the following pathologies:

• hypertension;

• atherosclerosis;
• lactase deficiency in the body;
• galactosemia.

The medicine is strictly prohibited during pregnancy and lactation. It is also contraindicated in men and women who have suffered a stroke - if the pathology occurred a month or earlier before the start of Tabex therapy. Under the supervision of doctors, treatment is carried out for any form of coronary heart disease and angina, even asymptomatic, vasospastic and microvascular. Also treated with caution for all vascular pathologies, stomach ulcers and diabetes mellitus, all forms of kidney and liver failure. Treatment requires increased attention if the patient has hyperfunction of the thyroid gland, schizophrenia, GERD and inflammation of the esophagus, diseases of the adrenal glands.

With alcohol

The drug cannot be combined with alcoholic beverages. When discussing compatibility with alcohol, it should be noted that alcohol negatively affects a person’s self-control. As a result, consumed alcohol can stimulate an overdose of nicotine. In addition, when taking alcohol and Tabex at the same time, a person may feel that such abuse leads to a noticeable loss of taste. In addition, the following side effects are possible:

• shortness of breath and rapid heartbeat;
• heartburn;
• increased blood pressure;
• increased craving for smoking.

Therefore, you should abstain from alcohol during the treatment process.

Reviews about Tabex

The majority of those who have been treated with this drug give positive feedback about Tabex. However, those who leave reviews about Tabex tablets note that this drug should be taken strictly according to the regimen that is described in the drug's annotation. Negative reviews on the forum are left by those who noted side effects in the form of irritability, etc. Also, those who have contraindications to taking them should not practice treatment with these pills.

Most former smokers note that with the help of this drug they were able to effectively and relatively easily get rid of this addiction.

Cheap analogues in Russia

Tabex is based on cetirizine. This is a remedy that eliminates nicotine addiction. It has an expensive price, about 1000 rubles. Therefore, many patients choose Russian-made analogues that have a lower price.

1. Nicorette. Nicotine based product. Its price is 2 times lower than Tabex. It is used as replacement therapy so that nicotine enters the human body, but in smaller quantities, bypassing the lungs. Gradually, the patient must give up tobacco addiction. Withdrawal symptoms are eliminated.
2. Niktivin. Nicotine based product. Used as replacement therapy to relieve symptoms of tobacco withdrawal syndrome. Its price is 600-700 rubles.
3. Champix. A drug that has a significantly better effect than Tabex. The cost is approximately the same. The effect occurs due to varenicline. This is a tobacco cessation substance used only after 18 years of age.

It should be borne in mind that drugs to eliminate smoking addiction have a large number of contraindications and side effects. If negative actions appear, they must be abandoned.

Tabex price, where to buy

The average price for Tabex in Moscow for a package of 100 pieces is 540 rubles.

The price in Ukraine for a package of 100 pieces is on average 160 UAH.

You can find out how much pills cost in a particular city by visiting the websites of popular pharmacy chains. Cost may vary. The average price in Kharkov with delivery is 180 UAH, without delivery – 150 UAH. Similar offers can be seen in pharmacies in Odessa and Dnepropetrovsk - here tablets are offered at prices ranging from 150 to 170 UAH

The price of Tabex anti-smoking tablets is quite reasonable compared to other anti-smoking products. Reviews of anti-smoking pills Tabex indicate that one course of treatment is enough to get rid of this bad habit. A specialist will tell you in more detail what exactly to start with in the process of choosing an effective remedy.

Where to buy Tabex depends on the person’s place of residence. You can buy the drug in Moscow and St. Petersburg at any pharmacy. In Krasnoyarsk, Tabex is sold in many pharmacy chains; it can also be purchased in online pharmacies. The drug is sold similarly in Ukraine.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Tabex tablets p.p.o.
  1.5 mg 100 pcs. Sopharma AD RUB 1,144 order

Pharmacy Dialogue

• Tabex tablets p/o No. 100Sopharma

  RUB 1,078 order

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PaniPharmacy

• Tabex tablets Tabex tablets.
  p/o 1.5 mg No. 100 Bulgaria, Sopharma 297 UAH. order

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Description and action

Tabex belongs to the group of drugs for the treatment of nicotine addiction. (Bulgaria). The price of the drug is 1020 rubles/100 tablets. The main active ingredient in the composition is cytisine, an alkaloid obtained from the seeds of the Russian broom plant. The tablets are biconvex, covered with a brown film, white inside. In addition to 1.5 mg of cytisine, each pill contains:

• lactose;
• talc;
• magnesium stearate;
• cellulose;
• dyes;
• macrogoal

Cytisine has a number of effects on the autonomic nervous system. After ingestion and absorption, this alkaloid excites the nerve ganglia, enhances breathing, and leads to the production of adrenaline by the adrenal glands. The drug also causes a slight increase in blood pressure. The mechanism of action is similar to that of nicotine, so cytisine begins to competitively suppress the effect of nicotine on specific receptors. This leads to a decrease in the need for smoking and a gradual decrease in nicotine addiction. Compared to nicotine, cytisine has much less toxicity.