Inflammatory eye diseases are one of the most common eye problems (about half of cases referred to ophthalmologists). The main symptoms of eye problems are itching, redness, and watery eyes. The most common disease is conjunctivitis, which is caused by various microbes, bacteria and infections.
Its appearance may depend on the season of the year and the use of allergenic cosmetics. In this case, doctors often prescribe taking the domestic drug Ophthalmoferon. It has a safe composition, a minimum of contraindications and adverse reactions. It can be taken by pregnant women, elderly people and children.
Ophthalmoferon is an eye drop that is an antiviral drug and has a broad effect.
Compound
1 ml of Oftalmoferon eye drops contains 10,000 IU of human recombinant interferon alpha-2b , as well as an additional active compound – 1 mg of diphenhydramine hydrochloride ( diphenhydramine ).
Auxiliary are: 3.1 mg of boric acid, 0.4 mg of disodium edetate, 2.2 mg of sodium chloride, 7 mg of sodium acetate, 3 mg of hypromellose, 5 mg of povidone 8000, 50 mg of macrogol 4000 and approximately 1 ml of purified water.
Analogs
Oftalmoferon eye drops have several analogues. They have a similar effect, but may differ in composition and degree of effectiveness:
- Albucid. The drug is especially effective in the treatment of bacterial conjunctivitis. The constituent elements penetrate deep into the eye and prevent the appearance and spread of harmful microorganisms.
- Alfarona. The medicine has an immunomodulatory and antiviral effect. Harmful pathogens develop immunity over time, so using the drug for long-term treatment is not recommended.
- Aktipol. Antiviral medicine. Takes an active part in restoring the damaged membrane of the eyeball. Drops relieve swelling and heal wounds that appear as a result of exposure to microbes.
- Poludan. The speed of penetration into the tissues and membrane of the eye is comparable to Oftalmoferon. The main component is polyriboadenylic acid.
Pharmacodynamics and pharmacokinetics
Ophthalmoferon is a combined drug containing an antiviral immunomodulatory antiproliferative substance - human recombinant interferon α-2b , which is supplemented with an active antihistamine - diphenhydramine .
Diphenhydramine acts by blocking H1-histamine receptors, which has an antiallergic effect, reducing swelling and itching in the human conjunctiva.
Pharmacokinetic properties
If you follow the instructions and apply eye drops topically, then systemic absorption does not occur - the concentration of the active substances of the drug in the blood is achieved significantly less than the standard detection limit (for example, for interferon α-2b - approximately 1-2 IU in 1 ml), which does not allows you to identify clinically significant reactions.
Contraindications and adverse reactions
Eye drops should not be taken if you have a personal intolerance to at least one of the constituent substances. The drug is also contraindicated for people prone to severe allergic reactions.
Usually the drug is well tolerated by patients. But if there is excessive sensitivity to the constituent elements, then adverse reactions may occur in the form of:
- swelling of the eyelids;
- burning sensation in the eye area;
- redness of the eyes;
- blurred vision.
These side effects do not pose a serious threat and disappear very quickly without medical help. You should not refuse to take drops because of this. If after taking the medicine the eyelids begin to swell and a rash appears in the eye area, then you will need to consult a specialist.
No cases of overdose have been identified.
Indications for use
- conjunctivitis of various types, including adenoviral , hemorrhagic ( enteroviral ), herpetic ;
- keratitis - adenoviral , herpetic (card-shaped, vesicular, dotted or tree-like);
- herpetic keratitis with stroma, which may be accompanied by corneal ulceration;
- or herpetic keratoconjunctivitis ;
- herpetic uveitis or keratouveitis (ulceration is possible);
- with dry keratoconjunctivitis (dry eye syndrome);
- prophylactic for graft disease , to prevent relapses of herpetic keratitis after keratoplasty ;
- prevention or treatment of complications after excimer laser refractive surgery on the cornea.
special instructions
Oftalmoferon is mainly used in combination with other medications to treat viral diseases.
For conjunctivitis of a viral nature, antibacterial drops or combined agents are prescribed together with it.
For allergic conjunctivitis - glucocorticoids and combination drugs.
After surgical interventions, they complement the effect of anti-inflammatory eye drops.
For corneal ulcerations, drugs that have a regenerating or healing effect (Korneregel, Solcoseryl) are additionally prescribed.
Oftalmoferon eye drops, instructions for use (Method and dosage)
The drug is used conjunctivally until symptoms disappear completely for various eye lesions or for prevention.
For viral diseases
Adults and children in the acute stage are prescribed 1-2 drops to be instilled approximately 6-8 times during the day. When positive dynamics appear and the inflammatory process is stopped, instillation can be reduced to 2-3 times.
For keratoconjunctivitis sicca (dry eye syndrome)
Recommended daily use - 1-2 drops twice a day for 25-30 days.
Instructions for the use of Oftalmoferon for preventive purposes
- Complications after excimer laser refractive surgery on the cornea of the eye: drops should be used daily from the first day of surgery according to the scheme: 1-2 drops. 2 times a day, course – at least 10 days.
- Graft disease or prevention of recurrence of herpetic keratitis that occurs after keratoplasty: the drug should be used daily according to the regimen: 1-2 drops. into the operated eye 3-4 times a day, the course is at least 14 days, starting from the first day after surgery.
Attention! When using contact lenses , drops can be used only after removing the lenses; they can be put on only 15–20 minutes after the instillation procedure.
Precautionary measures
The medicine combines well with other antimicrobial and anti-inflammatory drugs for the eyes. It is not recommended to exceed the prescribed dose.
Before use, you should remove the lenses (if any) from your eyes. You can put them on 20-25 minutes after using the drops.
Immediately after using the drug, blurred vision may be observed, so it is better not to drive a vehicle for half an hour after using the drops, the same applies to driving other dangerous mechanisms.
Newborns
Since Ophthalmoferon contains interferon and has an immunomodulatory and antiviral effect, it is more preferable for newborns. In addition, it has an antipruritic effect and restores damaged eye tissue, stopping the inflammatory process.
The drug is not contraindicated for newborns, however, before use, the mother should consult an ophthalmologist who, depending on the child’s age and the course of the disease, will determine the dosage and treatment regimen individually.
Pharmacology
The constituent elements of the drug are “immersed” in artificial tears, which are a complex of biopolymers that protect the cornea from local irritation, while providing a softening and lubricating effect. The protective film is characterized by excessive viscosity, which makes it possible to prolong the contact of the drug with the cornea and at the same time distribute the composition over the ocular surface.
Eye drops are an antibacterial and antiviral medicine that has found its use in ophthalmology. The product has a pronounced immunomodulatory and antibacterial effect. The drug also has anti-inflammatory activity and a local analgesic effect.
For inflammatory processes in the eyes, Oftalmoferon helps reduce the feeling of discomfort and burning, and also accelerates the tissue healing process.
When used topically, eye drops are not subject to systemic adsorption. The concentration of constituent components contained in the blood is much less than the permissible limit.
Oftalmoferon's analogues
Level 4 ATC code matches:
Florenal
Oksolin
Oxolinic ointment
Zirgan
Oftan I'm coming
Poludan
There are known analogues of eye drops that also have antiviral or immunostimulating effects:
- Aktipol
- Poludan
- Oftan-Idu
Prices and analogues
The drug has analogs that have identical effects. These include: Oftan-Ida, Aktipol and Poludan.
Analogues can only be used after consultation with a doctor.
Eye drops in a 10 ml bottle can be purchased for 300-400 rubles (depending on the region). Oftalmoferon is sold in pharmacies without a doctor's prescription.
Shelf life – 24 months, from the moment of opening – 1 month. Store in a dry place, out of direct sunlight and out of reach of children. Storage temperature from 3 to 8 degrees.
Reviews about Oftalmoferon
Today, Oftalmoferon eye drops are quite popular and in demand, reviews and discussions of which can be found on various Internet resources and forums. Most often, the comments are positive, because they can be used both in children and in elderly patients suffering from eye problems - various etiologies of conjunctivitis, “dry eye”, as well as for prevention purposes.
Mothers praise Oftalmoferon, noting its safety of use, availability, lack of itching and allergies.
Can it be taken by newborns?
Since the composition contains interferon and the drug has an antiviral and immunomodulatory effect, it can be given to newborns. In addition, they have an antipruritic effect and promote the regeneration of eye tissue, blocking inflammatory reactions.
Before applying eye drops to a newborn, parents should come for an examination by a specialist who, taking into account the age and condition of the baby, will be able to establish an individual treatment regimen and acceptable dosage.
Oftalmoferon price, where to buy
Many patients like the easy-to-use and affordable Oftalmoferon eye drops, the price of which does not exceed 350 rubles. for 10 ml. The price of eye drops of a smaller volume - 5 ml is usually up to 200 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Oftalmoferon drops hl.
10000 IU/ml 10 ml n1 ZAO Firn M RUB 327 order
Pharmacy Dialogue
- Ophthalmoferon (vial 10 ml eye/drop) Firn M
RUB 324 order
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Ingredients and release form
Drops are produced in sterile bottles of 5 and 10 ml. The active ingredients are:
- recombinant interferon. Has an antiviral effect and local immunostimulating effect;
- Diphenhydramine Has antiallergic, analgesic and anti-inflammatory effects;
- boric acid. It has an analgesic effect;
- "artificial tear" Performs a protective function and prolongs the effect of the drug.
The constituent components enhance the effect of the medicine.
Reviews from parents
Anna: My daughter goes to kindergarten - she either rubs her eyes with dirty hands, or puts a soft toy to them. Very often we develop conjunctivitis and the eye becomes sour. The doctor prescribed Oftalmoferon and Tobrex, improvements came on the third day. I have been using antiviral drops for up to a month, as a result the disease has begun to appear less frequently. I didn't notice any side effects.
Anton: After birth, my son’s eyes often festered; doctors tried not to prescribe antibacterial drugs. The pharmacy recommended Oftalmoferon - safe and effective. The only drawback is the need to store in the refrigerator.
Side effects
The medicine does not cause unwanted side effects. However, in case of individual intolerance or hypersensitivity to the components of the drug, the following actions may occur:
- increased tearfulness;
- redness, itching of the mucous membrane;
- burning sensation;
- other symptoms of an allergic reaction.
Additional substances included in the composition may cause intolerance reactions. If the symptoms do not go away or get worse, it is advisable to stop using the drops.
In addition to interferon, the drug contains diphenhydramine, which may be poorly tolerated.
Storage temperature
The recommended temperature (2-8 degrees Celsius) is maintained in the refrigerator. It is better to put the packaging in a special compartment intended for medications. It is usually located in a suitable temperature zone of the refrigerator and is isolated from the interior with a lid to prevent excess moisture from entering the compartment.
It is necessary to take into account compliance with these requirements when transporting the drug: drops should not be left at room temperature for a long time, especially in the sun. After 4-5 hours at high temperatures, the drops will lose their healing properties.
Reviews from doctors
Oleg Gennadievich, ophthalmologist: In pediatric practice for conjunctivitis, I often prescribe Oftalmoferon in combination with antibacterial drops and eye ointment. This scheme helps very quickly and well; before use, you need to rinse your eyes with green tea or chamomile decoction. The advantages of the drug are that there are no age restrictions or side effects.
Olga Sergeevna, ophthalmologist: For adults and children with viral eye diseases, I prescribe safe Russian drops Oftalmoferon. The only drawback is the relatively high price. The medicine is well tolerated at any age and can be combined with all types of other eye drops.
