Genferon Light suppositories 125000IU+5mg No. 10 - buy in Moscow, price in pharmacies from 354 rubles, instructions for use, reviews

Features of the composition of Genferon

The instructions indicate that the medicine is prepared in suppositories; the main active ingredients are presented:

human recombinant interferon alpha-2b;
taurine;
benzocaine.

The role of additional components is given to macrogol 1500, citric acid, dextran 60000, solid fat, sodium hydrogen citate, purified water, polysorbate 80, emulsifier T2.

Genferon is available in whitish or yellowish suppositories, packaged in cardboard packs of 5 or 10 pieces.

Composition and release form

Suppositories for vaginal or rectal use 1 sup.
- active substances: -
human recombinant interferon alpha-2 250000 IU
- taurine 0.01 g - anesthesin 0.055 g - excipients: solid fat; dextran 60000; polyethylene oxide 1500; twin 80; emulsifier T 2; sodium citrate; citric acid; purified water - a sufficient amount to obtain a suppository weighing 1.65 g in a blister pack of 5 pcs.; in a cardboard pack 1 or 2 packages.

active substances: - human recombinant interferon alpha-2 500000 IU

- taurine 0.01 g - anesthesin 0.055 g - excipients: solid fat; dextran 60000; polyethylene oxide 1500; twin 80; emulsifier T 2; sodium citrate; citric acid; purified water - sufficient quantity to obtain a suppository weighing 1.65 g in a blister pack of 5 pcs.; in a cardboard pack 1 or 2 packages.

active substances: - human recombinant interferon alpha-2 1 million IU

Contraindications and indications from the instructions for Genferon

Rectal or vaginal suppositories are prescribed for adults and children. In the latter case, the drug Genferon Light is used. The medication is suitable for the complex treatment of individual pathologies that provoke inflammation of the genitourinary

department:

for chlamydia, genital herpes;
mycoplasmosis, ureaplasmosis;
gardnerellosis, HPV;
trichomoniasis, bacterial vaginosis;
cervical erosion, vulvovaginitis;
cervicitis, adnexitis;
urethritis, balanitis, bartholinitis;
prostatitis, balanoposthitis;
thrush.

Genferon is contraindicated in patients with individual intolerance to the component composition in the first 4 months of pregnancy. Caution during therapeutic procedures is necessary for patients with acute diseases affecting the immune system.

Nosological classification (ICD-10)

— A49.3 Mycoplasma infection, unspecified — A56 Other sexually transmitted chlamydial diseases — A59 Trichomoniasis — A60 Anogenital herpetic viral infection [herpes simplex] — A63.8 Other specified sexually transmitted diseases — B37.3 Vulvar candidiasis and vagina (N77.1) - B97.7 Papillomaviruses - N34 Urethritis and urethral syndrome - N41 Inflammatory diseases of the prostate gland - N48.1 Balanoposthitis - N48.6 Balanitis - N70 Salpingitis and oophoritis - N72 Inflammatory diseases of the cervix - N74.4 Inflammatory diseases of the female pelvic organs caused by chlamydia (A56.1+) - N75.9 Bartholin's gland disease, unspecified - N76 Other inflammatory diseases of the vagina and vulva - N86 Erosion and ectropion of the cervix

Adverse reactions

Treatment with Genferon 10,000,000 IU can lead to non-standard responses of the body:

headache attacks, decreased levels of leukocytes and platelets in the blood;
painful sensations in joints and bones;
active work of sweat glands, increased temperature;
loss of appetite, rapid fatigue;
skin itching, rashes, and the appearance of red spots.

These symptoms are reversible and spontaneously disappear three days after stopping the suppositories.

Features of therapy

The instructions recommend the following procedures with Genferon:

Infectious and inflammatory pathologies of the genitourinary tract in women - depending on the disease, a suppository twice a day, for 10 days. Chronic and long-term forms of diseases - 1 suppository every 24 hours, for 1-3 months.
Lesions of the urogenital tract in men of an infectious-inflammatory nature - 1 suppository in the morning and evening, for 10 days.

The abstract does not indicate any reported cases of overdose. If a large amount of medication is accidentally used, therapy is stopped for 24 hours, then the patient should return to the previously prescribed regimen. If the treatment has caused non-standard symptoms, the patient should attend a consultation with a doctor and describe in detail the changes that have occurred. In some cases, it is necessary to replace the drug with an analogue.

Buy Genferon vaginal/rectal suppositories 500t IU No. 10 in pharmacies

Genferon Buy Genferon in pharmacies

DOSAGE FORMS suppositories 500000IU

MANUFACTURERS Biocad CJSC (Russia)

GROUP Antiviral agents of different groups

COMPOSITION Active substances: recombinant human interferon alpha-2, taurine, anesthesin.

INTERNATIONAL NON-PROPENTED NAME no

PHARMACOLOGICAL ACTION Genferon is a combination drug, the effect of which is determined by the components included in its composition. Has local and systemic effects. Interferon alpha-2 has antiviral, antimicrobial and immunomodulatory effects. Under the influence of interferon alpha-2, the activity of natural killer cells, T-helper cells, phagocytes, as well as the intensity of differentiation of B-lymphocytes in the body increases. Activation of leukocytes contained in all layers of the mucous membrane ensures their active participation in the elimination of primary pathological foci and ensures restoration of the production of secretory immunoglobulin A. Interferon alpha-2 also directly inhibits the replication and transcription of viruses and chlamydia. Taurine, which is part of the drug, has regenerating, reparative, membrane- and hepatoprotective, antioxidant, and anti-inflammatory properties. Anestezin is a local anesthetic. Reduces the permeability of the cell membrane to sodium ions, displaces calcium ions from receptors located on the inner surface of the membrane, and blocks the conduction of nerve impulses. Prevents the occurrence of pain impulses at the endings of sensory nerves and their conduction along nerve fibers. When administered vaginally or rectally, interferon alfa-2 is absorbed through the mucous membrane, enters the surrounding tissues, and enters the lymphatic system, providing a systemic effect. Also, due to partial fixation on the cells of the mucous membrane, it has a local effect.

INDICATIONS FOR USE As part of complex therapy for infectious and inflammatory diseases of the urogenital tract: genital herpes, chlamydia, ureaplasmosis, mycoplasmosis, recurrent vaginal candidiasis, gardnerellosis, trichomoniasis, papillomavirus infections, bacterial vaginosis, cervical erosion, cervicitis, vulvovaginitis, barto linitis, adnexitis, prostatitis, urethritis, balanitis, balanoposthitis.

CONTRAINDICATIONS Individual intolerance to interferon and other substances included in the drug. Use with caution during exacerbation of allergic and autoimmune diseases. Use in the second half of pregnancy is allowed if the benefits of the therapy outweigh the possible risk to the fetus.

SIDE EFFECTS Allergic reactions, namely skin rashes and itching. These phenomena are reversible and disappear 72 hours after stopping administration or reducing the dose. There may also be phenomena that occur with the use of all types of interferon alpha-2, such as chills, fever, fatigue, loss of appetite, muscle and headaches, joint pain, sweating, as well as leukemia and thrombocytopenia, but they occur more often with administering a dose of more than 10 million IU daily.

INTERACTION Genferon is most effective in combination with medications (including antibiotics and other antimicrobial drugs) used to treat urogenital diseases. It is recommended to simultaneously use vitamins E and C, which enhance the effect of interferon. Non-narcotic analgesics and anticholinesterase drugs enhance the effect of anesthesin. Anestezin reduces the antibacterial activity of sulfonamides.

METHOD OF APPLICATION AND DOSAGE Infectious and inflammatory diseases of the urogenital tract in women. 1 suppository (250,000 IU or 500,000 IU depending on the severity of the disease) vaginally 2 times a day every day for 10 days. In severe forms, 1 suppository 3 times a week, every other day, for 1-3 months. Infectious and inflammatory diseases in men. Rectally, 1 suppository (500,000 IU or 1,000,000 IU depending on the severity of the disease) 2 times a day for 10 days.

OVERDOSE No cases of overdose with Genferon have been reported.

SPECIAL INSTRUCTIONS No data available.

STORAGE CONDITIONS At a temperature of 2 to 8°C, keep out of the reach of children

Nuances of interaction and manufacturer's instructions

The instructions indicate the following features:

taking vitamins C and B enhances the activity of Genferon;
the bactericidal and bacteriostatic activity of sulfonamides decreases when combined with benzocaine;
Non-narcotic analgesics improve the effectiveness of benzocaine.

The greatest results with therapy with Genferon are recorded when combined with antimicrobial medications. The drug must be used with caution during menstruation due to the lack of sufficient clinical trials.

The drug is incompatible with alcohol; you should avoid drinking alcohol during therapeutic procedures. In the 2-3 trimester of pregnancy, the medication is used when obsessive itching, discomfort and other symptoms occur caused by an infectious-inflammatory lesion of the genitourinary tract.

Analogs

If unusual reactions of the body or signs of intolerance to the component composition occur, the drug requires replacement. The list of analogues is presented:

Vitaferon, Viferon, Viferon-Feron;
Laferobion, Laferon Farmbiotek, Kipferon;
Alfarekin, Alfarona, Bioferon;
Virogel, Gerpferon, Grippferon;
Introbion interferon alpha-2b, Intron A;
Lipoferon, Okoferon, Realdiron, etc.

The selection of a suitable remedy is carried out by the attending physician.

Pharmacodynamics

Genferon® is a combination drug, the effect of which is determined by the components included in its composition.
Has local and systemic effects. Interferon alpha-2 has antiviral, antimicrobial and immunomodulatory effects. Under the influence of interferon alpha-2, the activity of natural killer cells, T-helper cells, phagocytes, as well as the intensity of differentiation of B-lymphocytes in the body increases. Activation of leukocytes contained in all layers of the mucous membrane ensures their active participation in the elimination of primary pathological foci and restoration of the production of secretory immunoglobulin A. Interferon alpha-2 also directly inhibits the replication and transcription of viruses and acts on chlamydia. Taurine has regenerating, reparative, membrane- and hepatoprotective, antioxidant, anti-inflammatory properties. Anestezin is a local anesthetic. Reduces the permeability of the cell membrane to sodium ions, displaces calcium ions from receptors located on the inner surface of the membrane. Prevents the occurrence of pain impulses at the endings of sensory nerves and their conduction along nerve fibers.

Reviews

On the forums there are both neutral and positive responses about Genferon. Most reviews are related to treatment procedures in women during therapy for HPV, herpetic and cytomegalovirus infections. Good clinical results occur when treated with suppositories of 1 million IU.

Deterioration in well-being and an increase in temperature are associated with large dosages, especially when using suppositories for minors. To avoid the development of adverse reactions, the patient must strictly follow the doctor’s instructions, without deviations from the original regimen.