Compound
Complivit 45 Plus tablet contains:
- thiamine hydrochloride;
- ascorbic acid;
- folic acid;
- acetyl-L-carnitine hydrochloride;
- cyanocobalamin;
- riboflavin;
- alpha-tocopherol acetate;
- thiamine hydrochloride;
- rutoside;
- calcium pantothenate;
- nicotinamide;
- retinol acetate;
- selenium;
- magnesium;
- dried motherwort extract
- extract of the root part of black cohosh in dry form.
Additional components:
- potato starch;
- microcrystalline cellulose;
- ludipress;
- povidone;
- talc;
- Magnesium stearate.
The film shell contains the following components:
- yellow quinoline dye;
- indigotine (dye);
- macrogol;
- povidone;
- titanium dioxide;
- hypromellose.
special instructions
Do not exceed the recommended dose.
Caution is recommended in persons with liver disease, as well as when taking potentially hepatotoxic drugs concomitantly.
Urine may turn an intense yellow color, which is due to the presence of riboflavin in the drug and does not pose a danger.
Impact on the ability to drive vehicles and machinery
During the treatment period, care must be taken when engaging in potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
pharmachologic effect
Multivitamin combination preparation , which includes minerals, herbal medicinal extracts of black cohosh and motherwort, selenium and magnesium. Complivit 45 plus replenishes the lack of vitamins in the female body during hormonal age-related changes ( perimenopause ) based on daily needs.
Auxiliary components have a metabolic effect ( L-carnitine ), an adaptogenic effect (motherwort), and black cohosh restores the balance of hormones . Specialized production technology allows you to combine several active ingredients, minerals and vitamins in 1 tablet. The effect of the drug consists of the complex effect of all active substances.
Ascorbic acid regulates metabolism, activates the functioning of the endocrine glands, participates in the processes of collagen , the formation of steroids, and tissue regeneration; restores capillary permeability. Vitamin C stimulates the body, increasing its own defenses when in contact with infectious agents; prevents aging. Affects clotting .
Thiamine affects carbohydrate metabolism , participates in energy production processes, and is an integral component in the chain of impulse transmission along the neuromuscular pathway.
Riboflavin is involved in erythropoiesis , metabolism (protein, carbohydrate, fat), acts as an additional catalyst in the reactions and processes of cellular respiration , and is part of most enzymes . Vitamin B2 ensures the integrity of red blood cells and is required for the normal, full functioning of the visual analyzer .
Pyridoxine significantly reduces the risk of developing most cardiovascular diseases. It has a mild diuretic effect and normalizes the lipid profile . Necessary for the full functioning of the nervous system (peripheral and central sections), participates in the metabolism of carbohydrates and amino acids .
Pantothenic acid increases the body's resistance to contact with infectious agents. Eliminates intestinal atony, normalizes energy processes in the heart muscle. Vitamin B5 promotes epithelial and endothelial regeneration , participates in oxidation processes and acetylation reactions.
Folic acid has an antianemic effect and is involved in a variety of metabolic processes. Can increase endothelial thromboresistance.
Cyanocobalamin has a beneficial effect on the functioning of the nervous system, stimulates the synthesis of myelin , and is necessary for the metabolism of folic acid. It is the most important factor in normal epithelial growth and hematopoiesis, and takes part in the processes of nucleotide synthesis.
Nicotinamide lowers cholesterol , prevents the formation of chronic fatigue syndrome, takes part in carbohydrate and fat metabolism, and tissue respiration.
Rutoside normalizes capillary permeability and strengthens the walls of small vessels. Vitamin P is an antioxidant , participates in oxidative processes and reduction reactions, promotes the accumulation of ascorbic acid in tissue depots, and prevents oxidation.
Retinol supports the body's own strength and immunity . It has an antioxidant effect, is necessary for vision, and acts as a component of rhodopsin (a specific visual pigment). Participates in the development of the skeletal system; in the processes of synthesis, growth and maintenance of mucous membranes and skin.
Alpha-tocopherol acetate has been proven to slow down the aging process. It has a positive effect on the condition of the musculoskeletal system, the functioning of the sex glands, and the activity of the nervous system. Prevents the development of hemolysis (destruction), maintains red blood cells in a stable state, and has an antioxidant effect.
L-carnitine is able to mobilize adipose tissue from the depot and activate fat metabolism. Restores the structures of the elements of the nervous system, stimulates regenerative processes, participates in the synthesis of muscle tissue and protein metabolism. Has a beneficial effect on the functioning of the immune system. There is a positive effect on the cardiovascular system. Able to reduce the level of triglycerides in the lipid profile and total cholesterol in the blood. After prolonged physical activity, it restores the body's performance. Carnitine can increase exercise tolerance.
Cimicifuga helps normalize the levels of estrogen and LH hormones. It has hypotensive, muscle relaxant, sedative and antispasmodic effects. Eliminates the negative manifestations of perimenopause, exhibits angioprotective, antioxidant and hypolipidemic activity, improves the contractility of the heart muscle - myocardium.
Motherwort eliminates tachycardia, normalizes the functioning of the nervous system (central department), reduces the pressor effect of adrenaline on blood vessels, has a sedative calming effect, and reduces blood pressure .
Selenium, together with vitamins A, E and C, improves the body’s own adaptive forces under the negative influence of unfavorable factors (environment, tobacco smoking, stressful situations). Stimulates the immune system. It is an antioxidant of natural origin.
Magnesium stabilizes blood pressure to normal levels, has vasodilating and antispastic effects. It has a sedative effect and is necessary for the full and healthy functioning of the nervous system.
Complivit for women 45 plus ensures the supply of all substances necessary for the functioning of the body during hormonal changes.
Complivit For women 45 plus
Description The tablets are round, biconvex, film-coated, green in color, with a characteristic odor.
Pharmacotherapeutic group: Multivitamin + other drugs. ATX code: A11AB.
Pharmacological properties A combined multivitamin preparation containing the minerals magnesium and selenium, as well as extracts of medicinal plants motherwort and black cohosh. The vitamin complex replenishes vitamin deficiencies, taking into account the daily needs of women during age-related hormonal changes (perimenopause). Additional components of the complex have an adaptogenic effect (motherwort), a metabolic effect (L-carnitine), as well as a regulating effect on the hormonal balance of the woman’s body (cohosh). The compatibility of the components in 1 tablet is ensured by a production technology special for vitamin preparations. The pharmacological effect of the drug is determined by the properties of its constituent components. Ascorbic acid (vitamin C) – activates the activity of the endocrine glands, regulates all types of metabolism, blood clotting, tissue regeneration, the formation of steroid hormones, collagen synthesis, capillary permeability. It has a stimulating effect on the body as a whole, increases its adaptive capabilities, resistance to infections and adverse effects, and helps prevent the aging process. Thiamine (vitamin B1) - plays a key role in energy production processes, is involved in carbohydrate metabolism, and is a necessary component in the process of transmitting impulses along nerve fibers. Riboflavin (vitamin B2) is part of many enzymes and acts as a catalyst for cellular respiration processes. Participates in carbohydrate, protein and fat metabolism, in the synthesis of hemoglobin and erythropoietin. Necessary for maintaining normal visual function and the integrity of red blood cells. Pyridoxine (vitamin B6) – takes part in the metabolism of amino acids and carbohydrates. Ensures the normal functioning of the central and peripheral nervous system, normalizes lipid metabolism. Has a mild diuretic effect. Helps reduce the risk of developing cardiovascular diseases. Pantothenic acid (vitamin B5) – plays an important role in the processes of acetylation and oxidation; promotes the regeneration of epithelium and endothelium. Improves energy supply to the heart muscle, eliminates intestinal atony. Participates in maintaining the body's resistance to infections. Folic acid (vitamin Bc) is involved in various metabolic processes necessary for the synthesis of nucleic acids. It has an antianemic effect and increases endothelial thromboresistance. Cyanocobalamin (vitamin B12) – is involved in the synthesis of nucleotides, is an important factor in hematopoiesis and normal growth of epithelial cells; necessary for folic acid metabolism and myelin synthesis. Has a beneficial effect on processes in the nervous system. Nicotinamide (vitamin PP) – is involved in the processes of tissue respiration, fat and carbohydrate metabolism. Prevents the development of chronic fatigue syndrome. Helps reduce blood cholesterol. Rutoside (vitamin P) – participates in redox processes, has antioxidant properties, prevents oxidation and promotes the deposition of ascorbic acid in tissues. Strengthens the walls of capillaries, regulating their permeability. Retinol (vitamin A) – is involved in the processes of synthesis, growth and maintenance of the skin and mucous membranes. Vitamin A is important for vision as a component of the visual pigment rhodopsin and for skeletal development processes. Necessary for maintaining immunity, has antioxidant properties. α-Tocopherol acetate (vitamin E) – has antioxidant properties, maintains the stability of red blood cells, prevents hemolysis; has a positive effect on the functions of the gonads, nervous and muscle tissue, helps slow down the aging process of body tissues. L-carnitine – improves the functioning of the immune system, has a beneficial effect on the cardiovascular system, and is involved in protein metabolism and muscle tissue synthesis. Stimulates regeneration, activates fat metabolism, mobilizes fat from fat depots. Restores the structure of nervous tissue. Increases exercise tolerance and restores performance after prolonged physical activity. Helps reduce cholesterol and triglyceride levels in the blood, the excess of which is a potential risk factor for the development of a number of vascular diseases. Cohosh - normalizes the balance of estrogen and luteinizing hormone, has a mild sedative, muscle relaxant, antispasmodic and hypotensive effect, increases myocardial contractility, exhibits hypolipidemic, antioxidant and angioprotective activity, eliminates the symptoms of perimenopause. Motherwort - reduces the pressor effect of adrenaline on blood vessels, lowers blood pressure, normalizes the activity of the central nervous system, eliminates tachycardia, and has a calming effect. Selenium is a natural antioxidant that improves immunity. In combination with vitamins A, E and C, it has a pronounced antioxidant effect and improves the body’s adaptive characteristics under the influence of adverse factors (stress, smoking, environmental pollution). Magnesium is essential for heart function, has an antispastic vasodilator effect, and helps lower blood pressure. Necessary for the normal functioning of the nervous system, has a calming effect. As a result, the drug provides a balanced supply of components necessary to maintain optimal functioning of the body during the period of hormonal changes.
Indications for use Prevention of hypovitaminosis in women during age-related hormonal changes (perimenopause).
Contraindications: Individual intolerance to the components of the drug, pregnancy, lactation, childhood.
Directions for use and dosage : Adults. Orally after meals, 1 tablet 1 time per day, with a sufficient amount of liquid. If necessary, as prescribed by a doctor, the daily dose can be increased to 2 tablets. The minimum course duration is 3-4 months. Subsequent appointments and repeated courses as recommended by the doctor.
Side effects Allergic reactions to the components of the drug are possible.
Overdose In case of overdose, consult a doctor. Treatment:
activated carbon orally, gastric lavage, symptomatic treatment.
Interaction with other medications The simultaneous use of other multivitamin preparations is not recommended.
Special instructions Do not exceed the recommended dose. Caution is recommended in persons with liver disease, as well as when taking potentially hepatotoxic drugs concomitantly. Urine may turn an intense yellow color, which is due to the presence of riboflavin in the drug and does not pose a danger.
Release form: Film-coated tablets. 30, 60, 90, 100, 120 tablets in polymer jars for vitamins and medicines. 10 tablets in a blister pack made of polyvinyl chloride film and aluminum foil. Each jar or 3, 6 blisters along with instructions for use are placed in a cardboard pack.
Storage conditions At a temperature not exceeding 25°C. Keep out of the reach of children.
Shelf life: 1 year 6 months. Do not use after expiration date.
Dispensing conditions Without a prescription.
Owner of the registration certificate/organization accepting consumer complaints: PJSC OTCPharm, Russia, 123317, Moscow, st. Testovskaya, 10 Tel. Fax www.otcpharm.ru
Manufacturer: JSC Pharmstandard-UfaVITA, 450077, Russia, Republic of Bashkortostan, Ufa, st. Khudayberdina, 28, tel./fax, www.pharmstd.ru
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Level 4 ATX code matches:
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- Wellman;
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