Complivit, 60 pcs., film-coated tablets

It is necessary to register for pregnancy, as this allows for timely diagnosis of:

1. Pathologies of fetal development;
2. Chronic diseases in the mother that can affect the course and outcome of pregnancy;
3. Acute pathologies in the mother that occur during pregnancy, affecting the growth and development of the fetus and the health of the mother.

Pregnancy is a complex restructuring of the body; diseases in the mother are not always known if the examination is not completed before conception.

What happens to the body during the 1st trimester of pregnancy

The 1st trimester is considered from the moment of conception to 12 weeks of pregnancy.

Direct fertilization of the egg occurs in the abdominal cavity. After fertilization, the egg is located in the abdominal cavity and is actively fragmented into smaller cells and becomes similar to a raspberry or mulberry, such an embryo is called a morula. It is then captured by the villi of the fallopian tubes and moves into the uterine cavity. On the 7th day, the embryo attaches to the wall of the uterus. The fertilized egg begins to form, consisting of amniotic fluid and the yolk sac, from which the embryo will form. At 7-8 weeks, a fertilized sac and placenta are formed from the fertilized egg. From 8 to 12 weeks the placenta is finally formed (later on it only develops), it becomes visible on ultrasound. At week 12, the embryo looks like a full-fledged child measuring about 9 cm, its limbs, head and main internal organs are formed.

Mother's changes. Ideally, a woman does not feel pregnancy at all. The only sign is an enlargement of the mammary glands, due to the development of glandular tissue under the influence of hormones. The belly practically does not increase.

During pregnancy, many women experience so-called “toxicosis” - nausea and/or vomiting. This is due to an increase in the level of estrogen (in particular progesterone) and hCG (chronic gonadotropin). Moreover, these symptoms can complicate the life of a pregnant woman not only in the morning, but at any time of the day. Sometimes nausea or vomiting may persist throughout pregnancy.

There is such a serious complication as excessive (uncontrollable) vomiting in pregnant women, which leads to dehydration of the mother, disruption of the body's electrolyte balance, disruption of the liver and kidneys and encephalopathy, requiring hospitalization and treatment in a hospital.

It is best to eat according to your appetite. Food should not cause negative reactions, eat in small portions, pay attention to what food provokes nausea and try not to eat it for a while, listen to your body, usually the woman herself feels what she would like to eat. Don't forget that food should not only be desirable and tasty, but also healthy. It would be ideal to eat according to the “Harvard Healthy Eating Plate” method, when ½ of the plate’s volume is occupied by vegetables, ¼ by proteins (including plant-based), ¼ by complex carbohydrates (grains, potatoes, cereals, etc.).

Your body will also begin to change. And the first thing you will feel will be engorgement and increased sensitivity of the mammary glands, the nipples will swell a little and increase in size. It is important to wear comfortable, comfortable underwear and clothing to minimize discomfort. Sometimes there is pain in the nipples; your gynecologist may recommend ointments for this case.

We all remember that a pregnant woman becomes more vulnerable, whiny and even sometimes capricious. This is also associated with an increase in estrogen levels and requires patience and understanding on the part of family and partners. A calm environment at home and, if possible, at work is important. You can use relaxation methods such as walking, listening to your favorite music, aromatherapy if there are no reactions to odors. Think about what could bring back balance and calm to you?

The main pregnancy hormone, progesterone, causes fluid retention in the body. At the same time, the growing uterus puts pressure on the bladder and a frequent urge to urinate appears. This is normal, it is important to plan your day so that you always have the opportunity to visit the toilet.

Progesterone also reduces the tone of blood vessels, which can lead to dizziness. You can minimize these unpleasant sensations by changing your body position smoothly; do not stand up or sit down abruptly. Another reason for frequent dizziness may be a decrease in the level of magnesium in the blood; your doctor will help you figure this out.

Pregnant women often have an increased need for sleep, which is explained by the same effect of hormones, as well as the need for additional rest for the body, because there is a lot of work to carry, give birth and then feed the baby.

Under the influence of progesterone, the smooth muscles of the entire body relax (uterus, intestines, blood vessels, bile ducts and pancreatic ducts, etc.), the work of internal organs slows down, which in turn leads to constipation and heartburn. In addition to medication correction (prescribed by a doctor), split meals in small portions, foods rich in fiber (our favorite vegetables), sufficient fluid intake, feasible physical activity (physical therapy, walking, swimming, yoga, Pilates, etc.) help.

Unfortunately, sometimes pregnancy is overshadowed by pathology; let's talk about the most common problems in the first trimester of pregnancy.

Complivit Trimesterum 3 tabs No. 30

Compound

Excipients: talc 7 mg, potato starch 35 mg, citric acid 7.7 mg, low molecular weight povidone 16 mg, calcium stearate 7 mg, sucrose 68.86 mg.

Indications for use

Prevention of deficiency of vitamins and minerals included in the drug:

• during the third trimester of pregnancy (from 28 weeks of pregnancy to childbirth);
• during breastfeeding.

Contraindications

• hypersensitivity to the components of the drug;
• children under 14 years of age;
• hypervitaminosis A, hypervitaminosis D, increased levels of calcium and iron in the body, urolithiasis, B 12-deficiency anemia;
• sucrase/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption.

Directions for use and doses

Before use, you should consult your doctor.

Orally, without chewing, during or immediately after meals, 1 tablet 1 time per day with 1/2-1 glass of water (100-200 ml).

In the absence of special recommendations from a doctor, it is recommended to take Complivit® Trimester 3 trimester during the third trimester of pregnancy (from 28 weeks before birth), as well as during breastfeeding.

Storage conditions

In a dry place, protected from light, at a temperature not exceeding 25°C. Keep out of the reach of children.

Best before date

2 years. Do not use after the expiration date stated on the packaging.

special instructions

The purpose of the complex does not replace a balanced diet during pregnancy and lactation.

The simultaneous use of other multivitamin complexes is not recommended to avoid overdose.

In the third trimester of pregnancy, the daily dose of retinol (as part of the drug) should not exceed 5000 IU.

It is possible that urine may turn bright yellow, which is completely harmless and is explained by the presence of riboflavin in the drug.

Description

Multivitamin + multimineral.

Dosage form

Tablets, coated, white or almost white, round, biconvex; On a cross section, the tablets are brown with red, yellow, blue and white splashes.

Use in children

Contraindicated for children under 14 years of age.

Action

A combined multivitamin preparation with micro- and macroelements, the compatibility of the components in 1 tablet is ensured by a special technology for the production of vitamin-mineral complexes.

This vitamin and mineral complex was created specifically taking into account the changing needs of a woman’s body for vitamins and microelements at different stages of pregnancy. The effect of the drug Complivit® Trimester 3 trimester is due to the effects of its constituent components:

Vitamin A (retinol)

- necessary for bone growth, normal reproductive function, for the regulation of epithelial division and differentiation, as well as for the normal function of the retina of the eye. Retinol is involved in the formation of the organ of vision and skeleton during intrauterine development of the fetus.

Vitamin E (α-tocopherol)

- has an antioxidant effect: it inhibits the reactions of free oxidation of radicals and unsaturated fatty acids, prevents the formation of peroxides that damage cell membranes. Promotes normal growth and development of the fetus, reduces the risk of arterial hypertension during pregnancy.

Vitamin B 1 (thiamine)

- plays an important role in protein, carbohydrate and fat metabolism, as well as in the processes of nerve excitation at synapses. Participates in carbohydrate metabolism, as well as in the synthesis of nucleic acids, proteins and lipids.

Vitamin B 2 (riboflavin)

- regulates redox processes, participates in tissue respiration, carbohydrate, protein and fat metabolism, as well as in the synthesis of hemoglobin and erythropoietin. Necessary for normal growth and development of the fetus. Lack of riboflavin during pregnancy leads to fetal pathology: limb deformities, cleft palate, hydronephrosis, hydrocephalus, and congenital heart defects.

Vitamin B 6 (pyridoxine)

- participates in metabolism; necessary for the normal functioning of the central and peripheral nervous system. Helps increase the absorption of magnesium in the intestines, which helps prevent its deficiency during pregnancy. With a lack of pyridoxine, the risk of developing gestosis, anemia, and oligohydramnios increases.

Vitamin C (ascorbic acid)

- participates in the regulation of redox processes, carbohydrate metabolism, blood clotting, tissue regeneration; increases the body's resistance to infections. A lack of vitamin C increases the risk of premature birth. The need for vitamin C increases in the 3rd trimester of pregnancy.

Nicotinamide (vitamin PP)

- participates in the metabolism of fats, proteins, purines, tissue respiration. Reduces the risk of fetal malformations.

Folic acid

- participates in the synthesis of amino acids, DNA and RNA, stimulates erythropoiesis. Folic acid reduces the risk of complications during pregnancy that develop against the background of a deficiency in folic acid consumption: premature birth, premature placental abruption.

Calcium pantothenate

- a preparation of pantothenic acid - which plays an important role in metabolism: participates in carbohydrate and fat metabolism, in the synthesis of acetylcholine and steroid hormones; accelerates regeneration processes.

Vitamin B 12 (cyanocobalamin)

- participates in many metabolic processes and is necessary for DNA synthesis. Cyanocobalamin is involved in the formation of myelin, a component of the sheath of nerve fibers; If there is a deficiency of cyanocobalamin during pregnancy, the process of formation of the myelin sheath of the nerves may slow down in the fetus. Increases the resistance of red blood cells to hemolysis. Increases the ability of tissues to regenerate.

Vitamin D 3 (colecalciferol)

- participates in the regulation of calcium-phosphorus metabolism, increases the absorption of calcium in the intestines and the reabsorption of phosphates in the kidneys. Promotes bone mineralization, the formation of the bone skeleton and teeth in children, and is necessary for the normal functioning of the parathyroid glands. Deficiency of colecalciferol can lead to the development of rickets in a child, osteomalacia, and osteoporosis in a pregnant woman; it often occurs during breastfeeding.

Rutoside (rutin)

- has an angioprotective effect: it reduces the rate of water filtration in capillaries and their permeability to proteins. In the presence of venous insufficiency and lymphostasis, it reduces swelling of the lower extremities.

Thioctic acid (lipoic acid)

- plays an important role in the body’s energy balance, participates in the regulation of lipid and carbohydrate metabolism, has a lipotropic and antioxidant effect, improves liver function, and also improves the nutrition of nerve cells.

Lutein

- a carotenoid necessary for the normal functioning of the retina. It protects the eyes from damage resulting from exposure to ultraviolet light, is a component of the retinal antioxidant system, and also protects the retinal photoreceptors from oxygen radicals formed during the adverse effects of radiation of various origins on the eye.

Iron

- takes part in erythropoiesis; is an important component of hemoglobin, which ensures the transport of oxygen to tissues. Prevents the development of iron deficiency anemia during pregnancy and its consequences in children of the first year of life - disruption of the adaptation system and increased morbidity.

Manganese

- plays an important role in cell metabolism, is part of the active center of many enzymes, and is involved in protecting the body from the harmful effects of peroxide radicals. An imbalance of manganese in the fetoplacental system in pregnant women leads to disruption of ossification processes in the skeletal system of the fetus, which leads to intrauterine growth retardation and a lag in the physical development of children during the first year of life.

Copper

- necessary for normal absorption of iron, formation of connective tissue, blood cells. Copper deficiency provokes the development of breathing disorders in newborns.

Zinc

- participates in metabolism and stabilization of cell membranes. It is part of the main enzymes and participates in various biochemical reactions. Zinc stimulates skin regeneration processes and hair growth, and also has an immunomodulatory effect. Zinc is involved in cell division and differentiation; its deficiency leads to the birth of an immature and/or low-weight fetus, as well as the formation of malformations of various organs and systems.

Magnesium

- reduces the excitability of nerve cells, participates in many enzymatic reactions. Magnesium takes part in the formation of muscle and bone tissue, as well as in protein synthesis. Replenishes magnesium deficiency that occurs during pregnancy and reduces the risk of increased uterine tone, premature birth, intrauterine growth retardation, and late gestosis.

Calcium

- participates in the formation of bone tissue, the process of blood clotting, in the regulation of nerve conduction and muscle contractions, including maintaining stable cardiac activity. Calcium reduces the risk of complications caused by calcium deficiency, including those occurring during pregnancy and breastfeeding (decreased bone density and strength, bone and muscle pain, leg cramps, dental caries, arterial hypertension, palpitations) . Calcium is necessary for the formation of bones and teeth, the nervous system, the heart and muscles of the fetus and newborn; its use helps prevent rickets in children of the first year of life.

Selenium

- a microelement that is part of all cells of the body. Provides antioxidant protection to cell membranes and potentiates the effect of vitamin E. Selenium is necessary for the functioning of the immune system, as well as for the maturation of the surfactant system of the fetal lungs.

Iodine

- necessary for the synthesis of thyroid hormones and normal thyroid function; participates in lipid and protein metabolism. Reduces the risk of complications during pregnancy that develop against the background of iodine deficiency: gestosis and premature birth. Prevents the occurrence of congenital intrauterine malformations of the brain, disorders of the thyroid gland, musculoskeletal system, and retardation in physical and mental development.

Side effects

Allergic reactions may occur.

Sometimes nausea and vomiting may occur. Such phenomena can be caused both by pregnancy itself and by individual sensitivity to the iron included in the vitamin-mineral complex. If nausea occurs, it is recommended to take the drug in the afternoon, immediately after meals, with a sufficient amount of water.

Use during pregnancy and breastfeeding

Prescribed to prevent deficiency of vitamins and minerals during the third trimester of pregnancy and during breastfeeding.

Interaction

The drug contains iron and calcium, and therefore delays the absorption of antibiotics from the group of tetracyclines and fluoroquinolone derivatives in the intestine.

With the simultaneous use of ascorbic acid and short-acting sulfonamide drugs, the risk of developing crystalluria increases.

Antacids containing aluminum, magnesium, calcium, and cholestyramine reduce iron absorption. With the simultaneous use of diuretics from the thiazides group, the likelihood of developing hypercalcemia increases.

Overdose

In case of overdose, consult a doctor.

Treatment: temporary discontinuation of the drug, gastric lavage, oral administration of activated carbon, symptomatic treatment.

Impact on the ability to drive vehicles and operate machinery

There is no data on the effect of the drug on the speed of psychomotor reactions when driving a car and working with precision mechanisms.

The most common problems in the 1st trimester of pregnancy

Bleeding : due to a lack of progesterone, spasm and relaxation of the muscles of the uterus occurs and, accordingly, detachment of the ovum and bleeding (in severe cases, miscarriage). Also, with hypothyroidism, there is a violation of the implantation of the fertilized egg, which also leads to bleeding.

Thrombosis . During pregnancy, blood clotting increases (this is normal - the body is preparing for blood loss). To prevent thrombosis of the veins of the lower extremities, it is necessary to stop taking oral contraceptives 6 months before planning a pregnancy, and during pregnancy, maintain sufficient physical activity (long walks, swimming) and be observed by a doctor. If pain, swelling, or “cyanosis” occurs in the lower extremities, you should immediately consult a doctor.

Developmental anomalies and genetic pathologies . In the 1st trimester, abnormalities in the development of the fetus most often develop and manifest themselves, which can occur as a result of ionizing radiation, infectious diseases suffered during pregnancy (rubella, influenza, etc.), taking drugs prohibited during pregnancy (fluoroquinolones, macrolides, tetracyclines, tranquilizers , etc.), genetic pathologies and hereditary diseases.

Anemia . More often it happens due to iron deficiency, because. the fetus consumes a huge amount of it, taking away iron reserves from the mother, less often due to bleeding. B12 and folate deficiency anemia also occur, which is also associated with increased consumption and insufficient consumption by the mother. Anemia is dangerous due to chronic lack of oxygen, causing fetal growth restriction syndrome. In severe cases, it can lead to intrauterine fetal death.

Chronic diseases may worsen during pregnancy . This is due to the fact that the fertilized egg already carries part of the DNA that is foreign to the mother. To prevent egg rejection, the mother’s body suppresses its immunity throughout pregnancy, which affects the body as a whole. Therefore, all diseases that were not detected at the stage of preparation for pregnancy should be detected and treated. This applies mainly to infectious diseases. For example, exacerbation of chronic pyelonephritis, or herpes virus infection.

Also, during pregnancy there is a sharp restructuring of hormonal levels , which, in turn, affects somatic (non-infectious) diseases. For example, due to thickening of bile and compression of the gallbladder by the uterus, chronic cholecystitis may worsen. As the fetus develops, the islets of Langerhans (cells that produce insulin in the pancreas) sometimes do not develop quickly enough and the baby begins to consume the mother's insulin. If the mother has diabetes or impaired glucose tolerance (including hidden), both the child and the mother lack insulin, which leads to tissue damage to both the child and the mother (early aging of the placenta, delayed fetal development, premature birth, polyhydramnios, increased blood pressure in a pregnant woman, the formation of a large fetus, the risk of injury to the woman and child during childbirth and the most dangerous complication - intrauterine fetal death).

In addition, the fetal liver does not yet function as a detoxification organ, and all decay products produced by the child are forced to be processed by the mother’s liver. 2% of pregnant women develop benign cholestatic hepatosis of pregnancy - a violation of the formation and outflow of bile, which causes:

• Itchy skin, especially at night
• Digestive disorders (as bile is involved in the emulsification of fats)
• Inflammation of liver tissue due to toxic effects on cells and bile ducts