Causes of hemorrhoids
I'll try to tell you how I got my illness. I won't describe anything unusual. Most likely, hemorrhoids were acquired due to an unhealthy lifestyle. I work as a manager in a company specializing in the sale of metal-plastic structures. I move little, sit a lot and often get nervous.
If we add to this the large amount of strong coffee consumed per day and poor nutrition, then we have an almost complete list of indications for the use of Relief ointment. The only thing missing is genetic predisposition and obesity)))
I strongly recommend that people with a similar life schedule closely monitor their health. It is very important to start treatment in the early stages. Otherwise, you can easily wait until the need for surgical intervention. Judging by the reviews, Relief ointment is most effective at the very beginning of the disease, when problems manifest themselves as itching, burning and inflammation of the skin. If you miss these signs and wait until the nodes fall out, then you can safely prepare for surgery.
I made an appointment with a proctologist on time. Of course, there was embarrassment, but at least I avoided a bunch of unnecessary problems. That's what the doctor told me.
“Hemorrhoids are a common disease.
I don’t understand why people are so embarrassed about this disease. In the initial stages, treating inflammation is quite easy. There are many drugs that improve blood circulation and restore normal condition. I recommend Relief and a special diet. Usually this is enough...” Sergey Viktorovich, proctologist, Moscow
In general, the therapy is not very difficult, so I decided to start treatment immediately.
Indications for use of Relief ointment
I bought the prescribed drug immediately, on the way home from the hospital. It turned out that Relief ointment can be easily purchased in almost every pharmacy in the city. If therapy is not urgent and you want to save money, then order online, it’s a little cheaper.
What did I read in the description? It turns out that the external agent is recommended for use when:
- hemorrhoids of various types (external, internal);
- defects of the skin around the anus;
- the appearance of itching, burning in the anus;
- blood discharge during defecation.
From the reviews of my “sick colleagues”, I realized that Relief ointment is effective against any diseases associated with the blood flow. Despite the fact that the drug is sold without a prescription, it still has contraindications. The product should not be used by people suffering from pathologies of the circulatory system. Under certain conditions, the drug may worsen a thromboembolic condition.
Composition of the external agent
I would also like to dwell on the formula of Relief ointment. There are only two components, but they definitely complement each other and relieve symptoms. Swelling and itching quickly disappear due to the effect of phenylephrine hydrochloride. This element has a pronounced vasoconstrictor effect. Healing of cracks in the anal canal, relieving inflammation and bleeding occurs after using natural shark liver oil.
It would probably be useful to talk about excipients. In some reviews from people I have seen mention of an allergic reaction, so I will list everything that can cause it.
So, vitamin E, purified water, petroleum jelly, wax, alcohol, glycerin and thyme oil were added to Relief ointment. Allergy sufferers, check that you do not have intolerances!
Types of suppositories
Today, pharmacies offer 4 types of relief suppositories. When choosing a remedy, you should take into account the symptoms of the disease. It should be understood that successful treatment of hemorrhoids is only possible with an individual approach.
The most commonly prescribed treatment for internal hemorrhoids is classic relief. The components in its composition allow you to quickly stop bleeding and swelling. The main active substance in the classic drug is phenylephrine hydrochloride. It refers to adrenergic stimulants. The component has a local vasoconstrictor effect and improves blood circulation in hemorrhoids. Against this background, the release of exudate decreases and swelling is relieved. Thanks to the cocoa butter content, it has a pronounced softening effect. Due to its mild effect, classic relief is indicated for preventive purposes to prevent exacerbation of the disease. The drug has minimal side effects and can be used for a long time.
Other types of medicinal suppositories:
- Relief Advance. This remedy has a strong analgesic effect. The main active ingredient in the drug is benzocaine, which is a strong anesthetic. Suppositories are recommended for use in the acute stage of the disease, strangulation of the node, as well as after operations or during painful diagnostic procedures. The drug has a number of serious contraindications and can cause negative reactions in the body, so it should only be used if recommended by a doctor.
- Relief Ultra. The active ingredients in the product are zinc sulfate and hydrocortisone acetate. This combination provides a strong anti-inflammatory effect and allows you to quickly relieve itching. The product is an emergency aid for anal fissures. In the postoperative period, suppositories help prevent the development of the inflammatory process. It is allowed to use the product in short courses - up to 7 days. It is important to exclude the presence of contraindications before use.
- Relief Pro. The drug contains fluocortolone pivalate. This substance blocks the production of inflammatory mediators. The pronounced analgesic effect of suppositories is provided by lidocaine. The product is recommended for chronic pathologies that are accompanied by constant pain and inflammation. Due to the large number of side effects, the drug can only be used if indicated and recommended by a doctor.
Reviews of ointment for hemorrhoids Relief
Since we're talking about customer reviews, I'll give you a couple of examples from the Internet. The reputation of the external product is good. There is a negative, but it is usually associated with the low effectiveness of the ointment in the later stages.
“I used Relief strictly according to the instructions, but the loss of knots when going to the toilet did not disappear. I had to go to the hospital and sign up for surgery...”
If it comes to constant protrusion from the anus, then no cream will help. Most likely, this is already the third or even fourth stage.
“I didn’t delay and at the first symptoms of hemorrhoids I started rubbing Relief into the problem area. The procedure, I’ll tell you, is not pleasant, but I noticed the result after 3 days. The itching and burning went away. I hope that the effect will be permanent"
Feedback from people confirmed that the results of treatment last for a long time. The main thing is to change your lifestyle and start eating normally (it is important to get rid of constipation).
How to apply externally
I was diagnosed with the initial stage of external hemorrhoids. That is, all the nodes and bumps were located on the outside. This made the treatment much easier. From the instructions for Relief ointment:
- Wash the problem area. It is important not to use soap or dry the inflamed skin with a towel. It is better to blot with a paper napkin.
- Apply a small amount of ointment directly to the bulging node or bump.
- Rub the product into the skin using light, circular movements.
If you have internal hemorrhoids, you will have to use a special attachment. You need to very carefully insert the applicator into the anus and squeeze out the ointment. After this, you need to lie down without moving for 20-30 minutes.
The course of treatment usually does not exceed 5-7 days. The ointment can be applied up to 4 times a day. I did this 2 times - in the morning and in the evening. I felt an improvement already on the 3rd day (by the way, in the reviews many people wrote that the effect came on the first application).
Conservative treatment of hemorrhoids: experience with the use of Relief drugs
Hemorrhoids are a disease of external and internal hemorrhoids. Combined hemorrhoids are prolapse of internal hemorrhoids and external hemorrhoids at the same time. In chronic hemorrhoids, the main symptoms are bleeding and prolapse of hemorrhoids from the anal canal [1]. Hemorrhoids, like many diseases, have a wave-like character: a chronic course is replaced by exacerbation. Acute hemorrhoids are, first of all, thrombosis of hemorrhoids or bleeding hemorrhoids, complicated by anemia. Thrombosis of nodes can quickly, within 24 hours, be accompanied by an inflammatory process. Acute hemorrhoids are divided into three degrees: 1) thrombosis of hemorrhoids without inflammation; 2) thrombosis with inflammation in the node itself; 3) spread of the inflammatory process to the surrounding tissue. Often bleeding hemorrhoids are complicated by chronic anemia, less often - in 4-5% of cases - by acute anemia. The chronic course of hemorrhoids is divided into 4 stages. Stage I is characterized only by the discharge of scarlet blood from the anal canal during defecation without prolapse of the nodes. Stage II is characterized by prolapse of hemorrhoids with their independent reduction into the anal canal (with or without bleeding). At stage III, periodic loss of nodes requires their manual reduction into the anal canal (with or without bleeding). Stage IV is characterized by constant prolapse of hemorrhoids, sometimes together with the mucous membrane of the anal canal (with or without bleeding). Indications for drug treatment: 1) acute hemorrhoids; 2) chronic hemorrhoids of early stages; 3) perioperative period; 4) prevention of hemorrhoids [2]. Drug treatment of acute and chronic hemorrhoids consists of general and local use of analgesics, phlebotonics, anti-inflammatory, hemostatic and local combination drugs [3].
The place of conservative therapy in the treatment of hemorrhoids
Conservative treatment of hemorrhoids is based on a combination of systemic and topical medications. The leading place in systemic therapy is occupied by phlebotonic drugs, especially micronized diosmin with a hesperidin fraction. To eliminate thrombosis of hemorrhoids, pentoxifylline, acetylsalicylic acid and, of course, combined phlebotonic drugs are also taken in the form of systemic drugs. Drugs from the benzopyrone group also improve blood flow in hemorrhoids. The use of local drugs helps reduce pain and inflammatory syndromes, enhances the effect of systemic painkillers and phlebotonics, which reduces rehabilitation time. In the acute period, a 7–10-day course of treatment with local drugs is sufficient, and in the chronic course, as a preventive measure, the course can be continued for up to 1.5–2 months. Pathogenetically based pharmacotherapy solves a number of problems: 1) elimination of inflammation; 2) pain relief; 3) elimination of thrombosis of hemorrhoids; 4) stopping bleeding. To eliminate inflammation, non-steroidal anti-inflammatory drugs (NSAIDs), systemic enzyme therapy, various ointment forms containing NSAIDs, as well as phlebotonics are used. The anti-inflammatory effect of NSAIDs is ensured by inhibition of the biosynthesis of prostaglandins, which are important in the pathogenesis of inflammation and pain [4]. In acute thrombosis of hemorrhoids, topical combination drugs are more often used to relieve inflammation, such as tribenosine with lidocaine, a combination drug containing bufexamak, bismuth subgallate, titanium dioxide, lidocaine hydrochloride. These drugs have a venotonic and anti-inflammatory effect. They improve vascular tone, reduce venous congestion in the cavernous bodies, and improve microcirculation. Their anti-inflammatory effect is explained by the inhibition of endogenous substances that play the role of mediators in the development of inflammation. Lidocaine hydrochloride in the gel substrate has a rapid and long-lasting analgesic effect. To relieve pain in acute hemorrhoids, non-narcotic analgesics (antipyretics based on metamizole), paracetamol derivatives, as well as NSAIDs in the form of systemic and local therapy are usually used. The combination of topical drugs and NSAIDs has a pronounced anti-inflammatory and analgesic effect. For pain associated with acute anal fissure, complicating the course of hemorrhoids, antispasmodic drugs are effective, as well as derivatives of nitroglycerin and nifedipine on a special ointment base for topical use, which have an antispasmodic effect on the internal sphincter. To treat thrombosis in hemorrhoids, heparin-containing ointments and gels are used. The use of heparin-containing drugs promotes the regression of thrombosed hemorrhoids, reducing swelling and hyperemia of the skin, and the inflammatory reaction. Combination preparations containing sodium heparin, polidocanol, dexpanthenol and hydrocortisone are more effective. Heparin binds plasma coagulation and inhibits hemostasis, polidocanol provides an analgesic effect, dexpanthenol stimulates repair processes, and hydrocortisone has an anti-inflammatory effect. With acute bleeding hemorrhoids, chronic or acute anemia may develop, the severity of which depends on the activity of bleeding, its frequency, and the amount of blood loss. For systemic therapy for bleeding from hemorrhoids, a fairly effective drug, tranexamic acid, an activator of thromboplastin formation, sodium ethamsylate, and a heparin antidote, protamine sulfate, are used. The variety of forms and stages of hemorrhoids during its drug treatment requires an individual approach. For hemorrhoidal bleeding, local medications are mainly used. Of these, the α-adrenomimetic phenylephrine is quite effective, as well as sodium alginate, which reduces the polymerization time of fibrin monomer at the final stage of blood coagulation. In case of severe bleeding, collagen hemostatic sponges consisting of fibrinogen and thrombin are used for local treatment. After insertion into the anal canal, the hemostatic sponge dissolves and forms a fibrin film that blocks the bleeding areas of the hemorrhoids. To date, a local remedy, Relief, has been proposed for the treatment of various forms of hemorrhoids, represented by five drugs with different mechanisms of action [5]. They have analgesic, hemostatic, and pronounced anti-inflammatory properties, which are characteristic of certain forms of the Relief line of drugs. The different composition and, accordingly, the different predominant effect of each drug make it possible to take into account the clinical form, stage, and certain symptoms of hemorrhoids, which provides an individual approach to therapy. The drug Relief eliminates bleeding due to phenylephrine, which has a vasoconstrictor, decongestant, and antipruritic effect; The speed of the effect is ensured by the cocoa butter included in the base, which easily melts when the suppository is introduced. Relief suppositories are prescribed for the treatment of internal hemorrhoids with a predominance of edema and bleeding. Relief ointment contains natural corn and thyme oils in its base and is used to treat primarily external hemorrhoids. Relief Advance is a drug containing benzocaine that has a local effect, with minimal risk of side effects, and is indicated for the treatment of hemorrhoids with severe pain, as well as for use after proctological operations. Suppositories are used primarily for the treatment of internal hemorrhoids, ointment - for the treatment of external hemorrhoids. Relief Advance contains benzocaine, a local anesthetic that is safe because, due to its chemical structure, it has virtually no systemic effects. Relief Ultra is a drug with an anti-inflammatory effect, with a minimal risk of side effects, indicated for the treatment of exacerbations of hemorrhoids and other diseases of the anorectal area (fissures, erosion of the anus, proctitis, anal itching, eczema, dermatitis of the perianal area). A distinctive feature of the drug Relief Ultra is the presence of hydrocortisone in its composition, 10 mg in one suppository. Hydrocortisone acetate, which is part of Relief Ultra, has anti-inflammatory, desensitizing, antiallergic, vasoconstrictor and antipruritic effects. In the local treatment of acute hemorrhoids, hydrocortisone inhibits the release of important inflammatory mediators. The second component of the unique combination of Relief Ultra suppositories is zinc sulfate, which promotes the healing of wounds and erosions. Taken together, this provides a combined local effect of the Relief Ultra drug, and the base of the suppositories - cocoa butter - promotes rapid melting of the suppositories in the anal canal, which is especially important during the inflammatory process. In a randomized study in 60 patients with pathology of the anorectal region, the effectiveness of Relief ointment was studied [6]. The patients were divided into 2 equal groups (n=30), main and control. Each of them included 15 patients suffering from mixed hemorrhoids, and 15 patients after surgical interventions. After treatment with Relief ointment in the main group, 14 out of 15 patients with hemorrhoids (93%) noted a marked improvement in their general condition due to a decrease in pain and itching. All 15 patients in this group who underwent hemorrhoidectomy showed a significant reduction in swelling, itching and hyperemia, rapid cleansing of the wound from purulent-fibrinous contents, and easier defecation. Primary granulation and epithelialization appeared in the study group, on average, 2–3 days earlier than in the control group. The drug did not cause any allergic or toxic reactions and can be recommended for the treatment of hemorrhoids. The effectiveness of Relief Advance hemorrhoidal suppositories in patients with chronic hemorrhoids on an outpatient basis was demonstrated in a study by V.V. Darwin et al. [7]. The results of conservative treatment of 30 patients with chronic hemorrhoids who were undergoing outpatient treatment showed the effectiveness of Relief Advance suppositories. An excellent result on the 7th day was obtained in 46.7% of patients, on the 14th day – in 70%, on the 21st day – in 82.8%. The drug is especially effective in patients with stages I–II of the disease. A lesser effect of Relief Advance suppositories was noted when used in patients with stage III chronic hemorrhoids. In this case, Relief Advance can be a means of preparation for surgery, and also be included in the postoperative treatment program [7]. A.V. Sparrow et al. [8] studied the clinical effect of using rectal suppositories Relief, Relief Advance, Relief Ultra, and Relief Advance ointment in 32 proctological patients with various diseases of the anorectal area, as well as in the postoperative period. The control group consisted of 11 people who were not prescribed Relief group drugs. It was noted that the combination of Relief Advance suppositories and Relief Advance ointment turned out to be the most effective. The next in terms of analgesic effect were Relief Ultra suppositories, and Relief suppositories showed somewhat worse, although quite good results (Fig. 1).
Along with a decrease in pain, patients in the main group showed a more rapid decrease in swelling in the operation area, a decrease in the frequency of postoperative bleeding and accelerated wound healing. All operated patients were discharged at the end of the study after an average of 9±2 days. It is worth noting the good therapeutic effect as part of complex therapy of Relief Ultra suppositories containing hydrocortisone, and for such difficult-to-treat pathology as anal itching [8]. A study of the clinical effect of suppositories and Relief ointment in the treatment of inflammatory-vascular processes accompanied by pain and itching, in the treatment of cryptitis, papillitis, anal fissures, acute and chronic forms of hemorrhoids was presented in a study by T.V. Abuladze, which included 30 patients [9]. When using both forms of the drug, the analgesic effect occurred quickly and lasted up to 2–4 hours. The pain syndrome was relieved in 23 cases (77%), of which in patients with acute hemorrhoidal thrombosis - in 5 out of 5 (100%), chronic hemorrhoids - in 12 out of 14 (85.7%), with anal fissures - in 5 out of 5 (100% of cases). With repeated 6-day use, the effect was positive in all cases. The swelling subsided, the hemorrhoids decreased in size, and the pain was relieved. Thus, the treatment of both chronic and acute processes in the anal canal with Relief drugs gave a positive result. In an open study conducted at the coloproctology center of St. Petersburg, Relief Ultra suppositories were used in 35 patients with stage I–II hemorrhoids and in 23 patients with acute thrombosis of hemorrhoids. Relief Advance ointment was prescribed to 41 patients after various proctological operations. The control group included 70 patients who received traditional treatment (heparin ointment, syntomycin, levomekol). An excellent treatment result was achieved in 80% of patients - there was no pain and dysuric disorders, and the phenomena of hemorrhoidal vein thrombosis and inflammation quickly stopped. 17% of patients had a good treatment result, which consisted of an effective effect of the drug on the processes of healing and inflammation, while maintaining pain, for the relief of which analgesics were used. In 3% of patients, the drug was discontinued due to the development of intolerance (itching, hyperthermia) [10]. It is important to know that the majority of patients with hemorrhoids have irritable bowel syndrome, most often in the form of constipation, so such patients are required to undergo targeted treatment. It consists in the use of hydrophilic colloids, enzyme preparations, eubiotics and prokinetics. Treatment of irritable bowel syndrome is a prerequisite for the effectiveness of prevention and successful treatment of any form of hemorrhoids. After removing the inflammatory process, it is necessary to carry out treatment that improves the reparative properties of tissues. Deproteinized hemoderivative of calf blood, containing derivatives of nucleic acids and low-molecular peptides, improves the course of energy-dependent metabolic processes in the body. The drug improves the body's supply of oxygen and glucose, stimulates the activity of oxidative phosphorylation enzymes and improves microcirculation in tissues. An ointment containing microbial cells of Escherichia coli killed by phenol also has a local reparative effect. Its action is based on increasing local tissue resistance to the effects of pathogenic microflora. This process occurs with the help of cell wall antigens and metabolic products of Escherichia coli upon contact with the rectal mucosa and perianal skin. The drug stimulates the T-lymphocyte system of intestinal immunity, increases the phagocytic activity of leukocytes and cells of the reticuloendothelial system, normalizes the tone of blood vessels and stimulates the regeneration of damaged tissues. Pharmacoprophylaxis of hemorrhoids is necessary in risk groups: patients with constipation, leading a sedentary lifestyle, as well as pregnant women. In some cases, including during pregnancy, it is necessary to prescribe phlebotropic drugs. The question of their use during pregnancy and the postpartum period is decided individually. In addition, during pregnancy and the postpartum period, Relief can be used topically in case of bleeding from the anus or itching. For hemorrhoids with severe pain, it is advisable to prescribe Relief Advance in the form of suppositories or ointments. These drugs are approved for use in women of any stage of pregnancy. In a study by N.V. Knyazeva and S.N. Pernakova [11] on 110 patients showed that the drug Relief is an effective treatment for hemorrhoids and other diseases of the anorectal area in postpartum women in the late postpartum period. A positive result with the use of the drug Relief was achieved in 87.5% of patients: tissue swelling, itching in the perineum, discomfort, and bleeding disappeared. Elimination of itching and discomfort was observed within 5 minutes from the moment of introduction of the Relief suppository into the rectum. The authors conclude that the study drug in a dose of 1 suppository 2–4 times a day for 7–10 days is well tolerated by patients and rarely causes side effects.
Contraindications
First of all, systemic and local drugs intended for the treatment of hemorrhoids are contraindicated if there is a history of allergic reactions and intolerance to these drugs or their components. A relative contraindication to the use of heparin-containing agents is blood clotting disorders. In the first trimester of pregnancy, NSAIDs and glucocorticoids, both in systemic therapy and for local use, as well as systemic drugs for the treatment of hemorrhoids, are generally contraindicated. In the II–III trimester, postpartum period, and during breastfeeding, limited systemic and local use of drugs is possible, taking into account the risk-benefit ratio. Combined pharmacotherapy for acute or chronic hemorrhoids is accompanied by a long-term positive effect, but the resumption of constipation and a violation of the diet can again cause an exacerbation. Therefore, it is necessary to carry out the prevention of hemorrhoids in the form of 1.5–2 month courses 2 times a year, using small doses of combined phlebotonic drugs. Thus, the choice of method of conservative treatment of hemorrhoids depends on the severity of symptoms, and the simultaneous use of systemic and local treatment can quite effectively stop acute processes, reduce the number of exacerbations and prevent their development.
Average price of Relief ointment
Probably one of the main advantages of an external product is its cost. I bought the most expensive option (Relief Ultra) for 450 rubles. It would have been possible to take simpler options. Regular ointment costs from 200 to 350 rubles. Analogues are also inexpensive. The price of “Proctosan” or “Hepatrombin” does not exceed several hundred.
If you do not have allergic reactions, then it is better to use Relief ointment. This drug has a number of undeniable advantages over its competitors. First of all, it is a natural composition and high efficiency. From personal experience, I can confirm that an external remedy with shark liver oil accelerates the resorption of hemorrhoids, eliminates itching, burning and inflammation. No wonder the drug has so many positive reviews online)))
Votes: 3 3 points
Contraindications and negative reactions
A contraindication to the use of relief candles is individual intolerance to any components in their composition. Due to the fact that the products contain different substances, it is necessary to read the instructions for use before carrying out treatment.
Relief suppositories are contraindicated for thromboembolism and granulocytopenia. Treatment with elevated sugar levels should be carried out with extreme caution. Conditional contraindications include hypertension, hyperthyroidism, pathologies of the cardiovascular system, and hepatitis. It is not advisable to use relief suppositories during pregnancy and lactation. Suppositories are prescribed only after reaching the age of 12 years.
If contraindications are excluded and the doctor’s recommendations are followed, negative reactions of the body are rarely observed. Sometimes allergic reactions, increased blood pressure and increased heart rate occur. In such cases, you should stop using suppositories and consult a doctor.
Do not use relief candles if the packaging is damaged. This poses a risk of infection. Also, you should not use expired product.
