Contraceptive pills "Lindinet 20": reviews from gynecologists, instructions for use and effect

"Lindinet 20" is a combination drug produced in the form of tablets. It has a contraceptive effect and is used for planned, regular contraception. The composition includes gestodene and ethinyl estradiol, which in combination provide reliable contraceptive action. The drug inhibits the pituitary secretion of gonadotropins due to the action of estrogen-gestagens. The components of the drug prevent the maturation of the egg and prevent it from being fertilized. What else is included in Lindinet 20? Reviews will be presented below.

Ethinyl estradiol

Ethinyl estradiol is a highly effective component belonging to the group of estrogens. It is produced by the adrenal glands and ovaries and has an estrogenic effect. In combination with progesterone, ethinyl estradiol regulates the menstrual cycle, provokes the reproduction and division of endometrial cells and has a stimulating effect on the development of secondary sexual characteristics and the uterus in case of their insufficiency. In addition, this type of hormone can mitigate or completely eliminate complications due to dysfunction of the gonads and lower cholesterol levels in the blood. This is confirmed by the instructions for use for Lindinet 20 and 30. Many people are interested in analogues.

Lindinet 20 and alcohol – is there any reason for concern?

Oral contraceptives today are very popular among ways to prevent unwanted pregnancy. The market is replete with a huge number of contraceptive drugs. Hormones play the main role in them. Gynecologists warn about the dangers of unauthorized choice and indiscriminate use of birth control pills. It is especially dangerous to combine a contraceptive, for example, Lindinet 20, and alcohol. It must be remembered that unauthorized choice will lead to health problems and side effects. What suits one may harm another. A visit to a gynecologist can help in choosing oral contraceptives. The doctor will prescribe a hormonal test. The result will help you choose the best option in each individual case. Lindinet 20 - complete protection of the female body The effect of contraceptive drugs, their benefits and risks can be considered using the example of the drug Lindinet 20. Lindinet 20 is one of the modern monophasic gestagen-estrogen contraceptive drugs. Its purpose is to interfere with the process of ovulation and follicle maturation. Lindinet 20 has many advantages: 1. High degree of reliability in most oral contraceptive drugs, more than 95%; 2. Convenient dosage regimen; 3. Preventive action. The drug increases the viscosity of cervical mucus, which makes it difficult for sperm to penetrate the uterus. The pills are popular among the fairer sex because they have few side effects. Lindinet 20 can be used for several years, and it has a convenient dosage regimen. The drug Lindinet 20, in addition to the contraceptive effect, has many properties. 1.Normalizes the menstrual cycle; 2. Promotes stability of the monthly cycle; 3. Reduces the amount of blood loss during menstruation; 4. Reduces the development of iron deficiency anemia; 5. Reduces the manifestations of dysmenorrhea; 6. Significantly reduces the appearance of functional ovarian cysts; 7. Significantly reduces the possibility of ectopic pregnancy; 8.Improves skin condition in the presence of acne; Taking Lindinet 20 The drug is taken every day, one tablet for 21 days. After taking it, a seven-day break is taken. On the eighth day of the break, admission is resumed. Does alcohol affect the contraceptive effect of Lindinet 20? Lindinet20 and alcohol are compatible with moderate consumption of the latter. Moderate consumption is equivalent to 50 grams of vodka or 2-3 glasses of wine. Exceeding this alcohol limit leads to increased excretory function, which reduces the contraceptive effect due to the reduced concentration of hormones in the blood. If you take a large dose of alcohol, you should take care of an additional method of protection. Lindinet20 and alcohol can become enemies, in the literal sense. The regularity of taking the drug may suffer as a result of elementary forgetfulness (often occurs with alcohol abuse). Complications from alcohol when taking Lindinet 20 Women take Lindinet 20 for a long time - years and decades. In this regard, you need to have a correct understanding of the compatibility of tablets and alcohol. Lindinet 20 and alcohol are pharmacologically compatible. Complications directly related to the combined use of contraceptives and alcohol do not threaten a woman. There is another danger. Alcohol is an inhibitor of the liver enzyme system. Lindinet 20 is metabolized in the liver. The presence of alcohol in the liver changes the pharmacokinetics of the contraceptive and increases the concentration of ethinyl estradiol in the blood plasma. The consequences are dire: increased ethinyl estradiol content increases the likelihood of side effects - active hepatitis, liver cirrhosis and calcium metabolism. Ethinyl estradiol itself, while in the liver, inhibits (inhibits by feedback principle) other enzymes. It may alter the metabolism of ethanol and increase its concentration in the blood. In this case, intoxication will continue for a much longer time, and the hangover will become more pronounced and with complications. In itself, regular use of Lindinet 20 greatly increases the risk of negative reactions from the enzyme-cleavage system of the liver. The instructions for the drug itself indicate in detail the danger of developing cirrhosis and hepatitis. If, while taking Lindinet 20, a woman experiences problems with the liver, chronic or acute liver pathologies, taking birth control pills should be stopped immediately. Consequences of joint use of Lindinet 20 and alcohol According to the instructions for Lindinet 20, there is a direct connection between liver function and taking the contraceptive. Scientists have identified the decisive role of alcohol in the development of all liver pathologies. Women are strictly not recommended to combine alcohol intake with Lindinet 20. Alcoholic drinks provoke liver pathologies, but they do so quietly and secretly. Even one dose of alcohol is enough to cause serious illness of the gastrointestinal tract and liver. Improper liver function disrupts the metabolism of hormonal drugs, which threatens serious hormonal imbalance in a woman’s body. This condition is dangerous, it is difficult to correct and takes a very long time to return to normal. Scientists pay attention to the disinhibitory behavioral factor when drinking alcohol. A woman's behavior may approach immoral. In this case, there is often a violation of taking a hormonal drug, casual sexual intercourse, failure to maintain personal post-coital hygiene, which threatens unwanted pregnancy and infection with STDs (sexually transmitted diseases). When deciding whether to drink alcohol while taking Lindinet 20, a woman must correctly weigh the benefits and possible harm. The risks often outweigh any possible benefits of having a good time with alcoholic beverages.

Gestoden

The second active component of the drug is gestodene. This is a synthetic progestin that is similar in structure to levonorgestrel, but is superior in selectivity and potency. It inhibits the pituitary synthesis of luteotropin and follitropin, thereby blocking ovulation.

In addition to effects such as blocking egg fertilization, the contraceptive effect is due to a decrease in the sensitivity of the uterine endometrium to the blastocyst and an increase in the viscous properties of the mucus in the cervix, which creates an obstacle to the passage of sperm through it. Regular use of Lindinet 20 over a certain period of time, according to reviews from gynecologists, helps regulate the menstrual cycle and reduces the risk of pathologies of the woman’s reproductive organs, including neoplasms.

The drug should be prescribed by a doctor based on the collected medical history and taking into account the individual characteristics of the patient.

The effect of tablets on the body

Its effect is that it prevents a mature egg from entering the abdominal cavity. At the same time, the mucus of the cervix becomes thicker and does not prevent sperm from penetrating inside. In addition, the mucous layer of the uterus becomes thinner, which does not allow the fertilized reproductive cell to attach and develop further.

The compatibility of Lindinet 20 and alcohol is that all these abilities can decrease and the likelihood of pregnancy increases. If you follow all recommendations, the level of protection is 99%. Many doctors also say that the drug also has a therapeutic effect.

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Contraindications

The drug is contraindicated for use in patients with the following manifestations:

Individual intolerance to the components of the drug or hormones in a certain combination.
Tendency or presence of factors that can lead to venous thrombosis.
Ischemia as a precursor to thrombosis.
Irregular hypertension.
Damage to arteries and veins by thrombosis and thromboembolism.
Frequent migraines associated with neurotic disorders.
Surgery and, as a consequence, prolonged lack of physical activity.
Blockage of veins in close relatives (thromboembolism).
Dyslipidemic syndrome.
Diabetic angiopathy (as a consequence of diabetes mellitus).
Severe liver damage.
Cholelithiasis.
Neoplasms in the liver.
Pigmentary hepatosis (only some forms).
Yellowness of the skin as a result of taking steroid drugs.
Otospongiosis, severe itching.
Vaginal bleeding.
Pathological inflammatory processes in the pancreas with increased triglycerides in the blood.
Smoking, especially over the age of 35.
Tumors of the mammary glands and organs of the female reproductive system.
Lactation.
Pregnancy.

How to take Lindinet 20? Reviews confirm that this should be done only after consultation with a specialist.

Compatibility of tablets with alcohol

If you carefully read the instructions for the medication, you will not find any mention of this, although we should all remember that alcohol, even without other compounds, does not bring much benefit to a person. Since the drug is taken for a long time, you need to know what results such a combination can lead to. The most common manifestations of this may be:

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delay or inhibition of enzymatic and physiological processes;
increased concentration of ethinyl estradiol in the blood;
slowing down processes in the liver.

Consequences

Such changes when combining alcohol and Lindinet 30 (20) lead to hepatitis, liver cirrhosis or inhibition of calcium metabolism. Another manifestation of intoxication will take a longer time, but a hangover can be marked by painful symptoms. There is a disturbance in metabolic processes, which contributes to an increase in the concentration of ethanol in the blood.

In the note to the drug there is an indication that you should carefully monitor the normal functioning of the liver. If it malfunctions, you should immediately consult a doctor. Thus, alcohol can simply disrupt the normal functioning of the organ.

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You should think carefully about whether you can drink alcohol and Lindinet 20 or 30. A drunk person partially loses responsibility for all his actions. The contraceptive should be used at the same time every day. Thus, skipping a dose may not have the desired effect. If you take substances together, the amount cannot exceed a glass of cognac or 2-3 glasses of wine. Otherwise, negative consequences cannot be avoided.

Be healthy!

Careful reception

You should take the drug with caution in the following situations:

Development of azotemia, thrombocytopenia and hemolytic anemia (hemolytic uremic syndrome).
Liver diseases.
Quincke's edema caused by a genetic factor.
Conditions that increase the risk of thromboembolic or thrombotic damage to the arteries and veins, such as age over 35, family history, or smoking.
Diseases that appeared during pregnancy, as well as while taking other hormonal drugs: chloasma, herpes, porphyria, rheumatic chorea.
Obesity.
Hypertension.
Migraines of a regular nature.
Dislipoproteinemic syndrome.
Cramps.
Heart valve dysfunction.
A state of prolonged immobility.
Severe injuries.
Extensive operations.
Atrial fibrillation.

What other restrictions do the instructions for use indicate for Lindinet 20?

Superficial vein thrombophlebitis and varicose veins.
Postpartum period.
Depression.
Biochemical changes in blood composition.
Systemic lupus erythematosus (Libman-Sachs disease).
Diabetes mellitus that does not affect blood vessels.
Granulomatous enteritis.
Liver diseases in acute and chronic form.
Anemia (sickle cell).
Inflammatory processes in the colon against the background of ulcers.
Elevated levels of triglycerides (glycerol-based lipids) in the blood.

Lindinet 20, 63 pcs., 20 mcg+75 mcg, film-coated tablets

Before starting to use the drug, it is recommended to collect a detailed family and personal history and subsequently undergo a general medical and gynecological examination every 6 months (examination by a gynecologist, examination of a cytological smear, examination of the mammary glands and liver function, monitoring of blood pressure, cholesterol concentrations in the blood, urine analysis). These studies must be repeated periodically due to the need for timely identification of risk factors or contraindications that have arisen.

The drug is a reliable contraceptive drug - the Pearl index (an indicator of the number of pregnancies occurring during the use of a contraceptive method in 100 women over 1 year) when used correctly is about 0.05. Due to the fact that the contraceptive effect of the drug from the start of administration is fully manifested by the 14th day, it is recommended to additionally use non-hormonal methods of contraception in the first 2 weeks of taking the drug.

In each case, before prescribing hormonal contraceptives, the benefits or possible negative effects of their use are individually assessed. This issue must be discussed with the patient, who, after receiving the necessary information, will make the final decision on the preference for hormonal or any other method of contraception. The woman's health condition must be carefully monitored.

If any of the following conditions/diseases appear or worsen while taking the drug, you must stop taking the drug and switch to another, non-hormonal method of contraception:

— diseases of the hemostasis system;

— conditions/diseases predisposing to the development of cardiovascular and renal failure;

- epilepsy;

- migraine;

- the risk of developing an estrogen-dependent tumor or estrogen-dependent gynecological diseases;

- diabetes mellitus, not complicated by vascular disorders;

- severe depression (if depression is associated with impaired tryptophan metabolism, then vitamin B6 can be used for correction);

- sickle cell anemia, because in some cases (for example, infections, hypoxia), estrogen-containing drugs for this pathology can provoke thromboembolism;

- the appearance of abnormalities in laboratory tests assessing liver function.

Thromboembolic diseases

Epidemiological studies have shown that there is an association between taking oral hormonal contraceptives and an increased risk of arterial and venous thromboembolic diseases (including myocardial infarction, stroke, deep vein thrombosis of the lower extremities, pulmonary embolism). An increased risk of venous thromboembolic diseases has been proven, but it is significantly less than during pregnancy (60 cases per 100 thousand pregnancies). When using oral contraceptives, arterial or venous thromboembolism of the hepatic, mesenteric, renal or retinal vessels is very rarely observed.

The risk of arterial or venous thromboembolic disease increases:

- with age;

- when smoking (heavy smoking and age over 35 years are risk factors);

- if there is a family history of thromboembolic diseases (for example, parents, brother or sister). If you suspect a genetic predisposition, you should consult a specialist before using the drug;

— for obesity (body mass index above 30);

- for dislipoproteinemia;

- for arterial hypertension;

— for diseases of the heart valves complicated by hemodynamic disorders;

- with atrial fibrillation;

- with diabetes mellitus complicated by vascular lesions;

- with prolonged immobilization, after major surgery, surgery on the lower extremities, severe trauma.

In these cases, temporary cessation of use of the drug is assumed. It is advisable to stop no later than 4 weeks before surgery, and resume no earlier than 2 weeks after remobilization.

The risk of venous thromboembolic diseases increases in women after childbirth.

Diseases such as diabetes mellitus, SLE, hemolytic uremic syndrome, Crohn's disease, ulcerative colitis, and sickle cell anemia increase the risk of developing venous thromboembolic diseases.

Biochemical abnormalities such as resistance to activated protein C, hyperhomocysteinemia, protein C and S deficiency, antithrombin III deficiency, and the presence of antiphospholipid antibodies increase the risk of arterial or venous thromboembolic diseases.

When assessing the benefit/risk ratio of taking the drug, it must be borne in mind that targeted treatment of this condition reduces the risk of thromboembolism.

Signs of thromboembolism are:

- sudden chest pain that radiates to the left arm;

- sudden shortness of breath;

- any unusually severe headache that continues for a long time or appears for the first time, especially when combined with sudden complete or partial loss of vision or diplopia, aphasia, dizziness, collapse, focal epilepsy, weakness or severe numbness of half the body, movement disorders, severe unilateral pain in the calf muscle, acute abdomen.

Tumor diseases

Some studies have reported an increased incidence of cervical cancer in women who took hormonal contraceptives for a long time, but the results of the studies are inconsistent. Sexual behavior, infection with the human papillomavirus and other factors play a significant role in the development of cervical cancer.

A meta-analysis of 54 epidemiological studies found that there was a relative increase in the risk of breast cancer among women taking oral hormonal contraceptives, but the higher detection rate of breast cancer may have been associated with more regular medical screening. Breast cancer is rare among women under 40, whether they are taking hormonal birth control or not, and increases with age. Taking pills can be considered one of many risk factors. However, women should be made aware of the possible risk of developing breast cancer based on a benefit-risk assessment (protection against ovarian, endometrial and colon cancer).

There are few reports of the development of benign or malignant liver tumors in women taking hormonal contraceptives for a long time. This should be kept in mind when diagnosing abdominal pain, which may be associated with an increase in liver size or intra-abdominal bleeding.

The woman should be warned that the drug does not protect against HIV infection (AIDS) and other sexually transmitted diseases.

The effectiveness of the drug may decrease in the following cases:

missed pills, vomiting and diarrhea, simultaneous use of other drugs that reduce the effectiveness of birth control pills.

If the patient is concomitantly taking another drug that may reduce the effectiveness of birth control pills, additional methods of contraception should be used.

The effectiveness of the drug may decrease if, after several months of their use, irregular, spotting or breakthrough bleeding appears, in such cases it is advisable to continue taking the tablets until they run out in the next package. If at the end of the 2nd cycle menstrual-like bleeding does not begin or acyclic bleeding does not stop, you should stop taking the pills and resume it only after pregnancy has been ruled out.

Chloasma

Chloasma can occasionally occur in women who have a history of it during pregnancy. Those women who are at risk of developing chloasma should avoid contact with sunlight or UV rays while taking the pills.

Changes in laboratory parameters

Under the influence of oral contraceptive pills, due to the estrogen component, the level of some laboratory parameters (functional indicators of the liver, kidneys, adrenal glands, thyroid gland, hemostasis indicators, levels of lipoproteins and transport proteins) may change.

After acute viral hepatitis, it should be taken after normalization of liver function (no earlier than 6 months). In case of diarrhea or intestinal disorders, vomiting, the contraceptive effect may decrease (without stopping the drug, it is necessary to use additional non-hormonal methods of contraception). Women who smoke have an increased risk of developing vascular diseases with serious consequences (myocardial infarction, stroke). The risk depends on age (especially in women over 35 years of age) and the number of cigarettes smoked. During lactation, milk secretion may decrease; in small quantities, the components of the drug are excreted in breast milk.

The effect of the drug on the ability to drive a car and operate machinery.

Studies have not been conducted to study the possible effect of Lindinet 20 on the ability to drive a car or other machines.

Side effects

Contraceptive pills "Lindinet 20", according to reviews, are usually well tolerated. But there are still side effects.

The drug is completely discontinued for the following symptoms: porphyria, hypertension, hearing loss as a result of otospongiosis and hemolytic-uremic syndrome.

The following pathologies are rare: thromboembolism of the arteries and veins of the circulatory system, lower extremities, brain, lungs, as well as aggravation of lupus erythematosus (Libman-Sachs disease).

The most rare are thromboembolism of the arteries and veins of the liver, mesentery of the retina, kidneys and chorea. This is confirmed by the instructions for use and reviews for Lindinet 20.

Frequent manifestations

Common side effects include:

From the reproductive system: absence of menstrual bleeding after discontinuation of the drug, irregular vaginal hemorrhages and discharge, decreased libido, vaginal inflammation, changes in the state of mucus.
Discomfort, increase in size, soreness and galactorrhea of the mammary glands.
On the part of the digestive system: diarrhea, vomiting, nausea, granulomatous enteritis, pain in the epigastric region, ulcerative inflammation in the colon, vdenomatous liver damage, hepatitis, liver dysfunction, bile stagnation and cholelithiasis.
Allergic reactions: rashes, erythema, alopecia, increased pigmentation.
From the central nervous system: migraines, depression, headaches and emotional lability.
Weight gain and fluid retention, hyperglycemia, hypertriglyceridemia, decreased tolerance and absorption of carbohydrate compounds by the body as a result of changes in metabolism.
Decreased hearing function, feeling of discomfort when wearing contact lenses.
Hypersensitivity.

There are a lot of reviews from gynecologists about Lindinet 20.

Compatibility of the drug with alcoholic beverages

Lindinet and alcohol are a relatively safe mixture. Since estrogen and ethanol do not conflict with each other, and are also not mutual neutralizers, then, accordingly, their combination will not have negative consequences for the body and will not cancel the effect of contraceptives.

But you shouldn’t get carried away with alcohol - alcohol itself causes a blow to the reproductive system. At the same time, Lindinet 30, having a high concentration of the active substance, has a great inhibitory effect: some processes in the body and physiological functions slow down. The liver also begins to work more slowly. That is why it is better to consult with a specialist again after you have started taking a course of medication to determine exactly how the drug will affect your body.

special instructions

When deciding to take an oral contraceptive, you need to take into account the following features:

1. Lactation and pregnancy are absolute contraindications for use.

2. Before prescribing medication, the doctor needs to collect comprehensive information about the health of the patient and immediate family. Twice a year you need to undergo a gynecological and medical examination to eliminate the risk of contraindications and complications.

3. Research has clearly proven the high contraceptive effectiveness of Lindinet 20, since over the course of a year of use, pregnancy occurred in 0.05 percent of cases out of 100 women.

4. The maximum contraceptive effect is achieved two weeks after starting to take the pills, so during this period there is a need to use additional non-hormonal contraceptives.

5. The drug is prescribed taking into account the individual characteristics of the patient’s body. The specialist assesses the feasibility and necessity of prescribing Lindinet 20, informing the patient about possible side effects. While taking hormonal medications, regular gynecological monitoring is necessary. This is what the instructions for Lindinet 20 describe. Reviews from gynecologists are given below.

6. There are situations when it is necessary to completely stop using hormonal contraceptives and switch to other contraceptives. Such complications include: convulsions, impaired hemostasis and, as a result, the development of problems in the circulatory system and kidneys, migraines, diabetes, depression, poor blood tests for biochemistry, anemia and a high risk of neoplasms caused by taking hormones.

7. A scientifically proven fact is the relationship between taking hormonal drugs and the development of blood clots and thromboembolism in various systems and organs.

8. The risk of thrombosis and thromboembolism is especially high with the following factors: the patient’s age over 35 years, genetic predisposition, smoking, obesity, atrial fibrillation, hypertension, heart valve pathologies, etc.

9. During the postpartum period, the risk of thromboembolism increases significantly.

10. Deviations of biochemical blood parameters from the norm increase the risk of developing thromboembolism of veins and arteries. Bringing indicators back to normal reduces the likelihood of disease. The most common symptoms of thromboembolism are: shortness of breath, pain in the chest region, radiating to the left arm, headaches, causing blurred vision, dizziness, speech disorder, epilepsy, heart failure, numbness and weakness of the body, acute abdomen, pain in the calf muscle.

11. Studies have shown that taking hormonal contraceptives increases the risk of developing cervical cancer. The same applies to the development of breast cancer.

12. Oral hormonal contraceptives do not protect against sexually transmitted infections.

13. The appearance of pain in the abdominal area during long-term use of Lindinet 20 may indicate the development of a neoplasm (benign or malignant), which may be a sign of hepatomegaly or bleeding into the abdominal cavity.

14. The effect of taking the drug may decrease due to a missed pill, diarrhea, vomiting, or improper combination with other medications.

15. When taking a contraceptive simultaneously with drugs that reduce the contraceptive effect, it is necessary to use additional methods of contraception. There are reviews of gynecologists about this. Lindinet 20 may not be able to do its job.

16. A common complication during pregnancy is chloasma. It can also occur while taking oral contraceptives. If this possibility cannot be excluded, it is necessary to exclude exposure to ultraviolet radiation and sunlight during administration.

17. Estrogens can affect the kidneys, liver, thyroid gland and adrenal glands, causing changes in test parameters.

18. After treatment of a liver affected by a virus, taking Lindinet 20 is possible only after six months.

19. The effect of the contraceptive may be reduced as a result of severe intestinal disorders and vomiting.

20. Smoking while taking the drug can cause problems with blood vessels, especially after 35 years.

Lindinet 20

Use during pregnancy and breastfeeding

The drug is contraindicated for use during pregnancy and lactation.
The components of the drug are excreted in breast milk in small quantities.

When used during lactation, milk production may decrease.

Use for liver dysfunction

Contraindicated in case of liver dysfunction.

Use for renal impairment

The drug is not recommended for use in patients with kidney disease.

special instructions

Before starting to use the drug, it is necessary to conduct a general medical examination (detailed family and personal history, blood pressure measurement, laboratory tests) and gynecological examination (including examination of the mammary glands, pelvic organs, cytological analysis of a cervical smear). Such examinations during the period of taking the drug are carried out regularly, every 6 months.

The drug is a reliable contraceptive: the Pearl index (an indicator of the number of pregnancies occurring during the use of a contraceptive method in 100 women over 1 year) when used correctly is about 0.05. Due to the fact that the contraceptive effect of the drug from the start of administration is fully manifested by the 14th day, it is recommended to additionally use non-hormonal methods of contraception in the first 2 weeks of taking the drug.

The woman's health condition must be carefully monitored. If any of the following conditions/diseases appear or worsen while taking the drug, you must stop taking the drug and switch to another, non-hormonal method of contraception:

diseases of the hemostatic system;
conditions/diseases predisposing to the development of cardiovascular and renal failure;
epilepsy;
migraine;
the risk of developing an estrogen-dependent tumor or estrogen-dependent gynecological diseases;
diabetes mellitus not complicated by vascular disorders;
severe depression (if depression is associated with impaired tryptophan metabolism, then vitamin B6 can be used for correction);
sickle cell anemia, because in some cases (for example, infections, hypoxia), estrogen-containing drugs for this pathology can provoke thromboembolism;
the appearance of abnormalities in laboratory tests assessing liver function.

Thromboembolic diseases

Epidemiological studies have shown that there is a connection between taking oral hormonal contraceptives and an increased risk of developing arterial and venous thromboembolic diseases (including myocardial infarction, stroke, deep vein thrombosis of the lower extremities, pulmonary embolism). An increased risk of venous thromboembolic diseases has been proven, but it is significantly less than during pregnancy (60 cases per 100 thousand pregnancies). When using oral contraceptives, arterial or venous thromboembolism of the hepatic, mesenteric, renal or retinal vessels is very rarely observed.

The risk of arterial or venous thromboembolic disease increases:

with age;
when smoking (heavy smoking and age over 35 years are risk factors);
if there is a family history of thromboembolic diseases (for example, parents, brother or sister). If a genetic predisposition is suspected, it is necessary to consult a specialist before using the drug;
for obesity (BMI more than 30 kg/m2);
with dislipoproteinemia;
with arterial hypertension;
for diseases of the heart valves complicated by hemodynamic disorders;
with atrial fibrillation;
with diabetes mellitus complicated by vascular lesions;
with prolonged immobilization, after major surgery, after surgery on the lower extremities, after severe trauma.

In these cases, it is assumed that the use of the drug should be temporarily discontinued (no later than 4 weeks before surgery, and resumed no earlier than 2 weeks after remobilization).

Women after childbirth have an increased risk of venous thromboembolic disease.

It should be taken into account that diabetes mellitus, systemic lupus erythematosus, hemolytic-uremic syndrome, Crohn's disease, ulcerative colitis, sickle cell anemia increase the risk of developing venous thromboembolic diseases.

It should be taken into account that resistance to activated protein C, hyperhomocysteinemia, protein C and S deficiency, antithrombin III deficiency, and the presence of antiphospholipid antibodies increase the risk of developing arterial or venous thromboembolic diseases.

When assessing the benefit/risk ratio of taking the drug, it should be taken into account that targeted treatment of this condition reduces the risk of thromboembolism. Symptoms of thromboembolism are:

sudden chest pain that radiates to the left arm;
sudden shortness of breath;
any unusually severe headache that continues for a long time or appears for the first time, especially when combined with sudden complete or partial loss of vision or diplopia, aphasia, dizziness, collapse, focal epilepsy, weakness or severe numbness of half the body, movement disorders, severe unilateral pain in the calf muscle, symptom complex “acute abdomen”.

Tumor diseases

A meta-analysis of 54 epidemiological studies found that there is a relative increase in the risk of breast cancer among women taking oral hormonal contraceptives, but the higher detection rate of breast cancer may have been associated with more regular medical screening. Breast cancer is rare among women under 40, whether they take hormonal birth control or not, and increases with age. Taking pills can be considered one of many risk factors. However, the woman should be made aware of the possible risk of developing breast cancer based on an assessment of the benefit-risk ratio (protection against ovarian and endometrial cancer).

There are few reports of the development of benign or malignant liver tumors in women taking hormonal contraceptives for a long time. This should be kept in mind when differentially assessing abdominal pain, which may be associated with an increase in liver size or intraperitoneal bleeding.

Chloasma

Chloasma can develop in women with a history of this disease during pregnancy. Those women who are at risk of developing chloasma should avoid contact with sunlight or ultraviolet radiation while taking Lindinet 20.

Efficiency

The effectiveness of the drug may be reduced in the following cases: missed pills, vomiting and diarrhea, simultaneous use of other drugs that reduce the effectiveness of birth control pills.

If the patient is concomitantly taking another drug that may reduce the effectiveness of birth control pills, additional methods of contraception should be used.

The effectiveness of the drug may decrease if, after several months of their use, irregular, spotting or breakthrough bleeding appears, in such cases it is advisable to continue taking the tablets until they run out in the next package. If at the end of the second cycle menstrual-like bleeding does not begin or acyclic bleeding does not stop, stop taking the pills and resume it only after pregnancy has been ruled out.

Changes in laboratory parameters

Additional Information

After acute viral hepatitis, the drug should be taken after normalization of liver function (no earlier than 6 months).

With diarrhea or intestinal disorders, vomiting, the contraceptive effect may be reduced. While continuing to take the drug, it is necessary to use additional non-hormonal methods of contraception.

Women who smoke have an increased risk of developing vascular diseases with serious consequences (myocardial infarction, stroke). The risk depends on age (especially in women over 35 years of age) and on the number of cigarettes smoked.

The woman should be warned that the drug does not protect against HIV infection (AIDS) and other sexually transmitted diseases.

Impact on the ability to drive vehicles and operate machinery

No studies have been conducted to study the effect of Lindinet 20 on the abilities necessary to drive a car and operate machinery.

Directions for use and dosage of Lindineta 20

How to take Lindinet 20 (LS)? Reviews confirm that there is nothing complicated about this.

The drug is taken 1 tablet once a day; it is not advisable to change the time of administration. After three weeks of use, a week-long break is taken, after which a new package begins on the eighth day. During the break between doses of the drug, bleeding begins.

The first tablet should be taken from the first to the fifth day of menstruation. If you switch to Lindinet 20 from another hormonal contraceptive, then the first tablet is taken the day after the end of the previous drug. When switching from progestin medications, you can start taking them on any day of the cycle. After removal of the implant, you can start taking the drug the next day, after the injection before the last injection.

During the first week of use, you will need to use additional methods of contraception to avoid unwanted pregnancy.

The contraceptive effect continues even if you miss one pill. This is confirmed by reviews of gynecologists about Lindinet 20.

Lindineth

Contraceptive pill form. One package contains 21 tablets. The active ingredients are ethinyl estradiol (estrogen) and progestogen (gestodene). It interferes with the ovulation process and increases the viscosity of cervical mucus, thereby making it difficult for sperm to penetrate the uterus.

In addition to preventing unwanted pregnancy, Lindinet regulates the menstrual cycle, reduces pain and helps reduce the intensity of bleeding. For oily skin and acne - has a beneficial effect on oil levels, improves skin condition and intensity of rashes. The drug also inhibits the development of iron deficiency anemia, reduces the risk of cysts and tumors of the genital organs and mammary glands, the risk of ectopic pregnancy, pelvic inflammatory diseases and endometrial cancer.

Reception scheme

Lindinet is taken one tablet per day, preferably at the same time. The duration of continuous use is 21 days. This is followed by a week-long break, during which menstrual-like bleeding occurs. Then the reception continues - from the next package. It turns out that the menstrual cycle lasts four weeks, three of which the woman takes Lindinet, and one she does not take. Each new package starts on the same day of the week.

The first tablet is taken on the first day of the menstrual cycle. After an abortion, if it occurred in the first trimester of pregnancy, taking the drug can be started immediately after surgery. Additional barrier methods of contraception are not required. If it was not possible to start taking the drug immediately after the abortion, then you can do this after 21-28 days (in the first seven days you need to use barrier methods of contraception), or wait until the first menstrual cycle.

The same should be done after childbirth - start taking it after 21-28 days, using additional contraceptives during the first week. If you wait until your first menstruation, then follow the rule “the first day of the cycle - the first pill.” Please note: if you have had sexual intercourse after childbirth or abortion and menstruation has not yet begun, pregnancy must be ruled out.

If you forget to take your pill...

In such cases, you need to proceed according to the following schemes.

If the delay in taking is less than 12 hours, then you need to take the pill as soon as possible and continue to follow the usual regimen. No other contraceptive measures are required.

If the delay is more than 12 hours, the contraceptive effect is reduced. You should act in the same way, but additionally use barrier methods of protection for a week.

Separately, it is worth noting the situation when you forgot to take a tablet, and there are less than 7 tablets left in the package. In this case, you need to take the pill as soon as possible, then stick to your usual schedule, and start taking the drug from the next package without interruption. Menstrual-like bleeding does not occur in this cycle; it should occur only after completing all the tablets from the second package. However, spotting or breakthrough bleeding may occur while taking it. If bleeding does not occur in the second cycle, then a pregnancy test must be taken.

Vomiting and/or diarrhea that occurs within three to four hours after taking the drug may affect the effectiveness of the drug. If such symptoms bother you within an interval of up to 12 hours, you need to additionally take another tablet and then proceed according to your usual schedule. If symptoms continue for more than 12 hours, then the contraceptive effect is reduced and it is necessary to additionally use barrier methods of contraception over the next week.

Contraindications to taking Lindinet are:

liver diseases, dysfunctions and tumors;
thrombosis and thromboembolism - currently diagnosed or occurring previously;
myocardial infarction, heart failure;
cerebrovascular disorders;
transient ischemic attacks, angina pectoris;
sickle cell anemia;
breast or endometrial tumors;
diabetes mellitus complicated by microangiopathies;
uterine bleeding of unknown etiology;
idiopathic jaundice and itching during pregnancy;
history of genital herpes.

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Lindinet should not be taken during pregnancy and lactation.

Please pay special attention to the fact that taking other medications may reduce the effectiveness of Lindinet. Therefore, for any therapeutic appointments, inform your doctor that you are taking a contraceptive. It is recommended to use additional barrier methods of protection while you are taking the following drugs: ampicillin, tetracycline, rifampicin, barbiturates, carbamazepine, phenylbutazone, phenytoin, griseofulvin, topiramate, felbamate, oxcarbazepine, ritonavir. After completing the course of treatment, additional contraceptive measures should be used for the next week, or act in accordance with the doctor’s recommendations.

You should also know that a decrease in the contraceptive effect of Lindinet is caused by taking St. John's wort in any form (decoctions, infusions, etc.). The reason for this is the special effect that St. John's wort has on liver enzymes. This effect lasts during the course of taking St. John's wort, as well as for two weeks after its completion.

Side effects when taking Lindinet may be as follows:

nausea, vomiting;
emotional instability, irritability, depression, fatigue;
headaches, dizziness;
leg cramps;
increased blood pressure;
vaginal discharge of unknown origin;
change in body weight, change in libido;
pain in the lower abdomen;
chloasma;
swelling;
discomfort when wearing contact lenses;
allergic reactions.

The drug should be taken with extreme caution in the following cases:

family history of breast cancer;
kidney diseases;
chorea of pregnancy;
diabetes;
epilepsy;
gallbladder diseases, especially cholelithiasis;
liver failure;
cholestatic jaundice;
high blood pressure;
prolonged immobility (for example, in case of serious injury);
surgical intervention;
migraine.

Lindinet is not recommended for women over 35 years of age who smoke, as it may increase the risk of developing cardiovascular complications.

The drug should be stopped if:

while taking it, there is an increase in the frequency and intensity of headaches and migraines;
epileptic seizures occur;
signs of depression increase;
surgical intervention is pending (appointment is stopped 4 weeks before the planned operation and can be resumed 1 week after the patient is mobilized).

Please note: intermenstrual bleeding may occur in the first three months of taking Lindinet. If they occur after regular cycles have formed, pregnancy and malignant neoplasms should be excluded.

If menstrual-like bleeding does not occur during the period without taking pills (the week between two packs) and the dosage regimen was violated in the previous cycle, it is necessary to take a pregnancy test.

Reviews

Gynecologists characterize Lindinet 20 as a modern and relatively safe contraceptive. In the absence of contraindications for use, the drug does not have a significant effect on the woman’s body; on the contrary, it has a beneficial effect on the menstrual cycle, improves the quality of skin and nails. Side effects from the Gedeon Richter Lindinet 20 contraceptives, according to reviews, are extremely rare, and the most common include headaches, nausea and decreased libido.

If the drug does not suit you, you should not completely abandon oral contraceptives. In this case, it is necessary to additionally consult with a gynecologist and select another drug.

Price for "Lindinet 20" Tbl. p/o No. 21 (one blister in a cardboard package) - 400–480 rubles. “Lindinet 20” No. 63 (three blisters in a cardboard package) can be found at a price of 850–1100 rubles.

The main differences between Lindinet 20 and 30

Lindinet 20 and Lindinet 30 have respectively different dosages, a medication with a smaller amount of estrogen is intended only to prevent pregnancy, and a larger dosage is used to treat hormonal imbalance and painful periods. Lindinet 30 is prescribed only by a specialist so as not to cause harm. Therefore, it is not recommended to experiment with dosages on your own; it is better to consult a doctor.

There is no data on the incompatibility of Lindinet 30 with alcohol. Accordingly, it is also compatible with alcohol, since the active substance in it is the same as in the medicine with a lower dosage. But for more detailed comments, we again advise you to contact your treating gynecologist, who, taking into account your hormonal parameters and blood tests, will be able to tell whether this combination will harm you.