Author of the article:
Soldatova Lyudmila Nikolaevna
Candidate of Medical Sciences, Professor of the Department of Clinical Dentistry of the St. Petersburg Medical and Social Institute, Chief Physician of the Alfa-Dent Dental Clinic, St. Petersburg
Today everyone knows the importance of healthy intestinal microflora, however, not every one of us thinks about the impact of oral microflora on the health of teeth, gums and the entire body as a whole. Let's talk about how, if necessary, probiotics can help restore the microflora of the oral cavity.
Pharmacological properties
Pharmacodynamic parameters.
Bifidobacteria, a component of the normal human intestinal microbiota, are among the first to colonize the digestive tract of a newborn, are the dominant intestinal bacteria in breastfed children, and are essential for the development of a child at an early age. Protective and therapeutic effect of Bifidobacterium animalis subsp. lactis, which are contained in Linex®baby, is carried out in several ways: the specified strain limits the growth of pathogenic microorganisms in the gastrointestinal tract by preventing their adhesion to the intestinal wall and further colonization, as well as through competitive antagonism for food substrates, creating low pH values in the intestinal lumen due to production of acids, production of hydrogen peroxide and bacteriocins with antimicrobial properties. In addition, Bifidobacterium animalis subsp. lactis activates the immune response.
Disorder of the physiological balance of the intestinal microbiota due to the influence of pathogens of a viral or bacterial nature, infections of the digestive tract, antibiotic and chemotherapy, a delay in the composition of the normal composition of the intestinal microbiota during the neonatal period causes dyspeptic disorders - the occurrence of increased gas formation in the intestines, colic, defecation disorders, as well as the development of atopic dermatitis.
Thanks to the systematic use of Bifidobacterium animalis subsp. lactis effectively reduces the severity and frequency of manifestations of gastrointestinal disorders (diarrhea primarily) resulting from intestinal dysbiosis; conditions are created for normal intestinal activity. Linex® baby is used to prevent either as part of a complex treatment of atopic dermatitis, or to normalize the activity of the intestinal immune system.
Pharmacokinetic parameters. After administration of Bifidobacterium animalis subsp. lactis cause a local effect in the digestive tract. Pharmacokinetic parameters were not studied, since absorption into the systemic circulation does not occur. The resistance of the strain to the effects of gastric juice and bile ensures high survival of Bifidobacterium animalis subsp. lactis when passing through the upper gastrointestinal tract. Representatives of this strain form a stable adhesion to intestinal mucus and, due to peristaltic contractions and the act of defecation, are slowly excreted from the body.
Sandoz Linex dietary supplement for children - reviews
Amira Zh
https://protabletky.ru/linex/
The child had colic and loose stools from birth; not a single anti-colic drug helped. The child cried all day. The doctor threw up her hands and said we need to wait out the time. And so it went for 3 months. And at one of the appointments, another one took her place, and he prescribed us “Linex” for 10 days. There was no limit to the joy. The colic went away on the 4th day. Finally, the day I've been waiting for. "Linex" in capsules, you open and dissolve in water or milk and give to the child. In addition, we also took it along with antibiotics to prevent dysbacteriosis, it helped a lot.
Oksana Vladimirovna
https://flap.rf/Medicine/Linex/Reviews/7850131
Three years ago, I had surgery. Before and after the operation, I did not eat for 6 days. I was prescribed the drug "Linex". I had to take it for a month. Three days later, I felt the positive results of this medicine. During this month, while I was drinking it, it seemed to me that I was 10 years younger; I had not experienced such lightness in my stomach for a long time. I am very pleased with the result. It suited me perfectly.
I recommend the drug "Linex".
Loki_1985
https://citykey.net/review/udobnoe-lechenie-disbakterioza
Advantages:
convenient, helpful
Flaws:
expensive
Good day to all. During seasonal diseases, no, no, but you have to treat the child with antibiotics. And of course, the microflora of a little person needs protection and support. So we got sick and received antibiotics. We have accepted Linex before, but in the usual format. In capsules. It was a real hassle. The powder from the capsule does not dissolve; the baby did not want to take it from a spoon. I had to give this solution to him through a Nurofen syringe.
And of course, we spat out some of this liquid. This time we decided to try children's Linux. It was not in our pharmacies for a long time. And we didn’t regret it at all! Very comfortably! They dissolved it in warm milk, the child drank it without any screams. Hooray! It seemed to me personally that our stool improved on the third day. So it helps. Although of course a little expensive, it's worth it. It’s a good remedy, and most importantly it’s effective, and now we take it without stress for the baby!
olga26175
https://otzovik.com/review_4857326.html
Advantages:
Effect
Flaws:
Price
It all started when my daughter started vomiting, an ambulance, an injection. Not immediately, but my daughter felt better and fell asleep. In general, it was necessary to restore the microflora of the tummy. The pharmacy recommended diluting the powder with 50 ml of water. One sachet once a day. The dose is for children, so there is no need to divide anything. The powder dissolves completely in water; it only needs to be dissolved in cool or lukewarm water. Sold at any nearby pharmacy, either as a joke or completely packaged. The price of one piece is 40 rubles. The effect of the drug is good, it is advisable to take it for a month. But it’s up to you whether to buy or not and how much to take. Good day.
aliska-kiska
https://otzovik.com/review_1198850.html
Advantages:
Recommend. Helps
Flaws:
price
With the appearance of the first teeth in children, peace, nerves, and their own health are lost. I won’t say that we are suffering with every tooth our princess has, but the other day her fangs began to appear, and let me tell you, it’s tough! We had a bowel disorder, not to say that it was severe, but once a day and very loose stool. On the first day I held on, calming myself down, but on the second day I would again have one stool per day and loose. I'm a crazy mother, terribly suspicious. I grabbed my Fox under my arm and rushed to the pharmacy. There they advised us to use “Linex” for children. Cost 400 rubles, 10 sachets per package. We rushed home, read the instructions, it recommended adding one sachet per day directly to the bottle with the mixture. After two days of use, our stool became already formed. Oh Gods! I thanked all the saints. We still continue to drink, we decided to take a course.”Linex is not a medicine, which is good news. This is bad. The taste is slightly sweet, the child does not refuse to drink. I recommend to all.
Nata6enka
https://irecommend.ru/content/neobkhodimoe-dopolnenie-k-kursu-antibiotikov-ili-pustaya-trata-deneg-kak-govoril-komarovskii
It's fall, which means cold and flu season. So my baby got sick. Cough, fever for several days. The pediatrician prescribed us an antibiotic and immediately told us to take LINEX “to avoid intestinal flu.”
I decided to ignore the latter. As a result, on the second day after taking antibiotics, my daughter developed loose stools. I immediately ran to the pharmacy and bought LINEX for the children. I myself once took LINEX in capsules, so all this time I was thinking how I could give a capsule to a 1.5 year old child?!
The first thing that pleasantly surprised me was the release form. The medicine was a white powder, packaged in individual packages.
The second thing that turned out to be even more pleasant was the method of consumption. It can be mixed with any drinks! Do you agree that this greatly simplifies a mother’s life?!
The third thing that won me over was the absence of any foreign taste in the drink in which you dissolve the medicine. My daughter didn’t even notice that something was wrong and happily drank compote from a cup in which something was mixed... just shh....
And in conclusion the most important thing. What was my goal?! Normalize stool. The goal has been achieved! At the same time, he remained as regular as before - 1-2 times a day! This is a very important note, because I read that some children were constipated from Linex. But it should be noted that at that moment they were either on IV or GW.
And it seems that I was satisfied, the child is happy, everything is fine! But literally a couple of days after I started taking Linex, the program School of Doctor Komarovsky comes out, where he talks about dysbacteriosis... And then all my joy turns into small doubts.
So, what's the matter? Beloved by millions of mothers, Dr. Komarovsky pronounces several sentences that destroy my theory about the benefits of LINEX like a house of cards.
- a huge number of diseases can be accompanied by dysbacteriosis
- Dysbacteriosis is always a consequence
- eliminating dysbiosis does not affect the cause of its occurrence
- Elimination of the cause leads to the rapid elimination of dysbiosis.
- DYSBACTERIOSIS IS NOT A DISEASE
- there are no drugs that can treat dysbiosis
Then I looked carefully at the packaging and saw the treasured word dietary supplement... Tadadadam.... After watching the program to the end, I realized that all the “medicines” used as a “treatment” for dysbiosis are useless/not harmful. Moreover, all the beneficial bacteria contained in such preparations simply do not reach their destination, since they are influenced by saliva, bile, gastric juice, etc.
My specific conclusion is that I don’t see any point in taking the LINEX course for children. I gave it to my daughter exclusively for the 5 days that she was taking the antibiotic. She gave it, but she thought, is there any point... The choice is up to every mother.
Well, I wish you that you will never have to make this choice and that your children will be healthy and happy!
Chocolate_N
https://irecommend.ru/content/tolko-lineks-nam-i-pomogaet-analogi-kotorye-my-ispytali-na-sebe-i-vse-o-rezultatakh
Good evening everyone!
It just so happened that my child quite often suffers from various problems with bowel movements. We either have diarrhea or constipation and vice versa, and so on in a circle. Therefore, I tried to give him many medications so that everything would return to normal.
So today, we drink Linex for children, we caught a rotavirus infection and now we only have time to run to the bathroom and change diapers.
Every time this happens, I try to give analogues, there were bifidumbacterin and enterozermina (although it is also not cheap) and normabact. In general, a lot of things were tried, but nothing was better than Linex. And I'll explain why:
Firstly:
Result:
As soon as I start giving it to the child, the diarrhea immediately stops, the next day everything was fine. But I continue to give further, the course is 30 days, otherwise there is no point.
Secondly:
In addition to treating the main problem, Linex helps strengthen the immune system. And indeed it is.
I noticed this when it was cold season and my husband had a cold at home, but the child did not get sick. Although usually, he immediately catches all the microbes on himself.
Third:
Very convenient packaging
does not require special storage, i.e. all important probiotic microorganisms will not be killed if improperly stored or transported. In addition, drugs such as bifidumbacterin, lactobacterin must be consumed immediately after dilution and strictly on time, 30 minutes before meals, and this is simply unrealistic with a small child. But such drugs have a huge advantage - the price!
Fourth:
Linex is a multicomponent drug, i.e. it contains not one strain of bacteria, but several. While lactobacterin, acipol, acylact contains only lactobacilli, and bifidumbacterin, bifiform contains only bifidobacteria. And when restoring the microflora, the intestines need to be populated with both.
In addition, Linex is not a medicine, it is a dietary supplement (biological food supplement).
Pharmachologic effect:
Normalizes intestinal microflora. Maintains and regulates the physiological balance of intestinal microflora (microbiocenosis), ensures its physiological functions in the intestine.
Bacteria in Linex® restore the disturbed balance of intestinal microflora due to dysbacteriosis.
Live lactic acid lyophilized bacteria included in its composition are an integral part of the normal intestinal microflora, maintain and regulate the physiological balance of microbiocenosis in all parts of the intestine, have pronounced antagonistic properties against pathogenic and conditionally pathogenic flora, and participate in the synthesis of vitamins B1, B2, B6, B12 (in nature they are synthesized only by microorganisms), PP, K and E, folic and ascorbic acids, provide the body's need for biotin, and have immunostimulating properties. By producing lactic acid and lowering the pH of the intestinal contents, the microorganisms used create favorable conditions for the absorption of iron, calcium, and vitamin D. Lactic acid bacteria carry out the enzymatic breakdown of proteins, fats and complex carbohydrates (including lactase deficiency in children) that are not absorbed into the body. In the small intestine, carbohydrates and proteins undergo deeper breakdown in the large intestine by anaerobes (including bifidobacteria). The bacteria included in the drug facilitate the digestion of proteins in infants (bifidobacteria phosphoprotein phosphatase is involved in the metabolism of milk casein); participate in the metabolism of bile acids (formation of stercobilin, coprosterol, deoxycholic and lithocholic acids; promote the reabsorption of bile acids).
Indications for use:
Prevention and treatment of dysbacteriosis.
Dysbacteriosis and its manifestations (diarrhea (“diarrhea”), constipation, flatulence, nausea, vomiting, abdominal pain, regurgitation in infants), dyspepsia (digestion) in adults and children, including infants.
Dysbacteriosis as a result of treatment with antimicrobial and antitumor (“chemotherapeutic”) drugs
The only contraindication is hypersensitivity to dairy products or components of the drug.
I would name only one drawback - the price! Because You need to drink 3 packs, otherwise it’s better not to start. And the price of one is on average 20 Belarusian rubles. But what can’t you do for the happiness and health of your child!
Health to you and your children!
special instructions
In case of fever above 38 °C, duration of diarrhea for more than 2 days, severe diarrhea with exacerbation and loss of body weight, the appearance of mucus or blood in the stool, intense abdominal pain, if the child has a chronic pathology such as cardiovascular diseases or diabetes mellitus, immunodeficiency conditions (for example, HIV infection), before using the drug, you should consult a doctor for advice.
In children under 6 years of age, treatment for diarrhea should be under medical supervision.
When treating diarrhea, adequate correction of water and electrolyte balance is also necessary.
Due to the lack of relevant studies, there is no information on the effect on reaction speed when operating vehicles or other machinery.
Microflora of the oral cavity
The human oral cavity is a unique ecological system. The permanent microflora in the mouth is formed by hundreds of different organisms; a moist, relatively warm environment creates favorable conditions for their reproduction.
The following play a significant role in the composition of the normal microflora of the oral cavity:
- veillonella, which neutralize acidic foods;
- bacteria of the genera Propionibacterium, Corynebacterium and Eubacterium, producing molecular oxygen;
- lactobacilli;
- rod-shaped lactobacilli - producers of lactic acid;
- bifidobacteria, necessary for the fermentation of carbohydrates and the production of B vitamins and others.
It is difficult to overestimate the importance of healthy oral microflora for the body. It is in this environment that the primary process of food digestion occurs, and therefore the absorption of vitamins and nutrients. Normal microflora is necessary for the proper functioning of the immune system and protecting the body from various fungal, bacterial and viral infections.
With the uncontrolled proliferation of opportunistic microflora and an imbalance of bacteria in the oral mucosa, oral dysbiosis occurs, an extremely unpleasant disease that provokes damage to tooth enamel and gums and can lead to extremely serious consequences for the entire body.
Note!
Description of the drug Linex Baby por. d/oral. susp. package 1.5g No. 10 on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.
How do you know when it’s time to restore the microflora?
Untimely treatment of dysbiosis can lead to tooth loss. Therefore, at the slightest sign of disease, it is important to consult a dentist as soon as possible. Based on an examination of the oral cavity and test results, the doctor will prescribe effective treatment for the pathology and, if necessary, recommend probiotics and lactobacilli for the oral cavity.
Dentists divide dysbiosis into several stages:
- Dysbiotic shift is a mild increase in the number of one of the types of opportunistic microorganisms. The general composition of the microflora does not change.
- Subcompensated dysbacteriosis. The number of beneficial microorganisms decreases slightly against the background of increased activity of opportunistic bacteria.
- Monoculture, in which beneficial microorganisms are replaced by a pathogenic monoculture, and lactobacilli in the oral cavity are absent or remain in the form of traces.
- Decompensated, in which the microflora is populated by associations of pathogenic bacteria, as well as yeast-like fungi.
At the initial stage, dysbiosis manifests itself in the form of sticking in the corners of the mouth and an unpleasant odor. At later stages of development, the disease manifests itself with symptoms such as:
- dry mouth;
- coating on the tongue;
- tartar;
- unpleasant taste in the mouth;
- point inflammation on the gums;
- bad breath;
- plaque;
- compaction and blisters on the mucous membrane;
- regular inflammation of the tonsils.
Features of application
Before starting to use Linex Forte®, you should consult your doctor in the following cases:
- body temperature above 38°C;
- the presence of hidden blood or mucus in the stool;
- duration of diarrhea for more than 2 days;
- intense diarrhea with dehydration and weight loss;
- diarrhea, accompanied by severe abdominal pain.
Use during pregnancy or breastfeeding
There are no reports of undesirable effects when using the drug during pregnancy and lactation. However, if diarrhea is severe, precautions must be taken to avoid fluid and electrolyte deficiency or other unwanted effects that may pose a threat to the fetus or pregnant woman. Relief of symptoms of diarrhea in pregnant women and during breastfeeding should be carried out under the supervision of a doctor. Since there is not enough data regarding the use of the drug during pregnancy and lactation, it is not recommended to use it during these periods.
Children
Used in pediatric practice.
The ability to influence the reaction rate when driving vehicles or other mechanisms
No data available.
Treatment of dysbiosis
Remember, a disorder of the oral microflora is a complex, multifaceted and very individual disease that cannot be cured solely with probiotics. Such substances are used only as adjuvant therapy.
Dysbacteriosis should be treated only by a dentist based on smears from the mucous membrane. Therapy should be selected taking into account the general condition of the body and associated pathologies.
As a rule, the treatment of dysbiosis involves a whole range of measures and includes:
- rinsing the mouth with disinfectant solutions;
- use of special medicated toothpastes;
- the use of drugs aimed at restoring normal microflora with bifidobacteria and lactobacilli;
- taking lozenges, tablets and lozenges to eliminate pathogenic microorganisms and simultaneously restore normal microflora;
- changing the diet - including vitamin supplements in order to activate the body’s protective properties;
- taking immunomodulatory drugs to stop the development of pathogenic microflora and increase immunity;
In rare cases, with dysbiosis, dentists may prescribe antibiotics.
An assistant in restoring the microflora of the oral cavity is the probiotic complex ASEPTA PARODONTAL. This is an excellent source of lactobacilli for restoring the microflora of the oral cavity - it not only normalizes the bacterial microflora in the mouth, but also prevents the formation of biofilms of pathogenic microorganisms, reducing the formation of dental plaque - one of the factors in the occurrence of periodontal inflammation and caries.
So now you know a lot about probiotics and oral lactobacilli. We hope that you will not need treatment with such supplements, and the state of your microflora will always be excellent.
Mode of application
Children aged 1 to 2 years: 1 capsule 1 time per day.
Children aged 2 to 12 years: 1 capsule 1-2 times a day (depending on the severity of symptoms).
Adults and children over 12 years of age: 1 capsule 1-3 times a day (depending on the severity of symptoms).
Children under 6 years of age should be treated for diarrhea under medical supervision.
The use of the drug for the treatment of infants under 1 year of age is not recommended. For this age group, it is recommended to use Linex Baby®, powder for oral suspension.
If the patient cannot swallow a whole capsule, it must be opened and the contents of the capsule mixed with a teaspoon of liquid (tea, juice, sweetened water). The resulting mixture cannot be stored.
To ensure maximum effectiveness, it is recommended to take the drug with food. Linex forte® capsules should not be taken with alcohol or hot drinks.
The drug should be taken until the patient's condition improves.
The duration of treatment depends on the cause of the disease and the individual characteristics of the body.
If diarrhea does not go away within 2 days, despite taking the drug, you should consult a doctor.
When treating diarrhea, special attention should be paid to replenishing lost fluids and electrolytes.
