Substitutes for Wobenzym: TOP 9 analogues in gynecology


Wobenzym is a combination of highly active enzymes of plant and animal origin with anti-inflammatory, decongestant, immunomodulatory, fibrinolytic and secondary analgesic effects. The use of Wobenzym improves oxygen saturation of tissues and improves metabolism. Taking Wobenzym prevents negative reactions after taking hormones. It enhances the effectiveness of taking antibacterial drugs, since Wobenzym increases their concentration in the blood and plasma. The drug affects cholesterol synthesis and lipid metabolism.

Enteric coating

Drugs that are damaged by the acidic environment of the stomach are coated with a substance that protects the drug from dissolving until it reaches the small intestine. This protective coating is called an “enteric coating.” For these coatings to dissolve, they must interact with the less acidic environment in the small intestine.

Substance content in 1 tablet: Proteolytic enzymes from papaya, pineapple, animal pancreas - 250 mg; pancreatin - 100 mg; rutin - 50 mg, amylase - 10 mg; lipase - 10 mg; trypsin - 24 mg, chymotrypsin - 1 mg; bromelain - 45 mg; papain - 60 mg.

Pharmacological action, pharmacodynamics and pharmacokinetics

The main effects of Wobenzym:

  • anti-inflammatory;
  • fibrinolytic
  • antiplatelet;
  • immunomodulatory;
  • decongestant.

The active components of the drug reduce the number of active circulating ICs in the blood, activates immunity directed against tumor cells and phagocytosis, thereby exerting its immunomodulatory effect.

The drug also normalizes the permeability of vascular walls, reduces the infiltration of damaged tissues, thereby reducing swelling and accelerating the time of resorption of bruises and hematomas.

Wobenzym regulates blood viscosity, normalizes the number of formed elements, thereby improving rheological parameters and microcirculation in tissues.

It is absorbed from the small intestine quite quickly, enters the bloodstream, where it interacts with carrier proteins, thanks to which it enters the organs where pathological processes occur.

Indications

The drug Wobenzym is indicated in complex therapy for the following diseases:

  • In dermatology it is used for skin acne, dermatitis, eczema and other inflammatory skin diseases.
  • In urology for – sexually transmitted infections, cystitis, prostatitis.
  • In cardiology for – heart attack, angina pectoris.
  • In gynecology – various infectious diseases, gestosis, to reduce undesirable effects of hormone therapy.
  • In pulmonology for pneumonia and inflammation of the paranasal sinuses.

And also in gastroenterology, nephrology, endocrinology, rheumatology, neurology, ophthalmology, surgery, pediatrics, traumatology.

Popular anti-inflammatory drugs

Ibuprofen

The drug fights all types of pain, including inflammation of the joints, and relieves fever. Often used for pain due to cramps that occur during menstruation.

Available in tablet form.

Ibuprofen Welfarm tab 0.4 x 30
Ibuprofen tab 0.2 x 50
Ibuprofen tablet p/p 400 mg x 10
Ibuprofen tab 0.2 x 20

Diclofenac

Prescribed for the treatment of rheumatic diseases. Reduces swelling and stiffness of joints in the morning. Increases motor range in case of joint diseases. A stable effect is achieved after 1-2 weeks of treatment.

Diclofenac amp 25mg/3ml x 5 (Grotex)
Diclofenac amp 25mg/3ml x 10
Diclofenac amp 25mg/3ml x 5

Dolgit

Product for external use. Thanks to the phenylpropionic acid derivative in its composition, it relieves pain and inflammation. Effectively combats joint stiffness in the morning and provides increased mobility in the joints.

The dosage form is cream in tubes.

Dolgit gel 5% 100 mg

Voltaren Emulgel

Topical preparation. Intended for adults and children over fourteen years of age.

Diclofenac in the composition helps relieve discomfort and relieves inflammation. The gel-like emulsion is quickly absorbed into the skin, which provides almost instantaneous action.

Relieves swelling of injured joints, muscles, tendons, soft tissues. Relieves pain from tendinitis, bursitis and rheumatism.

Available in gel form in tubes.

Voltaren Emulgel 1% 100 mg

Nurofen Express Forte

The drug is in capsule form. Designed to relieve pain of various origins. A popular remedy for menstrual and neuralgic pain. For colds and flu, it relieves discomfort in muscles and joints. The medicine can be taken by adults and children from the age of twelve. It is not allowed to take more than three tablets per day.

Nurofen Express Forte 400 mg No. 20

Meloxicam

The medicine blocks the body's production of substances that cause inflammation and pain. Has antipyretic properties. Reduces sensitivity, relieves discomfort, stiffness and inflammation in osteoarthritis and rheumatoid arthritis. Normalizes the condition of juvenile rheumatoid arthritis that occurs in childhood.

Meloxicam tab 7.5 mg x 20
Meloxicam-Prana tab 15mg No. 20
Meloxicam-Prana tab 7.5 mg No. 20

Amelotex

The drug is based on Meloxicam. Increases the motor volume of joints. In a short time it fights inflammation and discomfort thanks to its chondroprotective properties.

The course of treatment is three to four weeks. Amelotex should be applied twice a day.

The dosage form is gel.

Amelotex gel 1% 30g

Nise

Product based on Nimesulide. The active substance, in addition to relieving pain, removes swelling. Has antioxidant properties.

The drug relieves symptoms of osteoarthritis, rheumatism, neuralgia, fever, bursitis, tendonitis, ankylosing spondylitis.

Nise gel 1% 100g

Dolobene gel

The active ingredient is ibuprofen, a component that relieves inflammation and pain. The duration of treatment is determined by the doctor. Usually for injuries, including sports, it is two weeks, for rheumatic diseases - three weeks.

It is used to relieve inflammation and swelling of soft tissues, treat bruises, deformations, and sprains.

Release form: gel in tubes.

Dolobene gel 90g

Nimesil

Often used after surgery. Effective for diseases of the musculoskeletal system (arthritis, arthrosis, etc.) during periods of deterioration of health. Fights fever caused by infectious diseases or other reasons. The drug is good for improving the condition of soft tissues and joints. It is used for therapy in urology, gynecology, disorders of the vascular system, and degenerative changes in the body.

Available in the form of granules for preparing a suspension.

Nimesil granules for suspensions 100 mg No. 30

Nimesulide

Clinical studies have shown that Nimesulide is able to relieve pain in a relatively short time - about twenty minutes. This allows the drug to be used to combat acute conditions.

Indications for use are arthritis, tendinitis, pathologies in the field of gynecology, infectious diseases, inflammatory processes after surgery.

Nimesulide Welfarm tab 100 mg x 20
Nimesulide-lect tab 100mg No. 40
Nimesulide gran d/susp pack 100 mg x 30

Ketonal Duo

Relieves pain, inflammation, fever. Thanks to the prolonged action, relief is felt longer.

After consumption, the drug is absorbed directly from the gastrointestinal tract into the blood, where it is maximally concentrated after about a couple of hours.

Release form: capsules with gradual release of the active substance.

Ketonal Duo capsules 150g No. 30

Ketoprofen

Topical application in gel form.
It is used in the presence of morning stiffness of the joints, weakens the course of arthralgia. Effectively helps relieve muscle pain and combat post-traumatic lesions. Before using the drug, it is worth considering other treatment methods. If treatment with Keptrofen is necessary, it is recommended to use the smallest dosage and the shortest time of use, based on the expected results of therapy.

Ketoprofen gel 2.5% 40g

Movalis

Contains meloxicam, a derivative of enolic acid. Intended for the initial stage of therapy and short-term symptomatic treatment. It is not combined with other drugs from the list of non-steroidal anti-inflammatory drugs and cannot be used together with them.

Available in the form of a solution for intramuscular injection.

Movalis solution 15 mg No. 3

Revmart

Indications for use are inflammation of the joints and their degenerative changes, which are accompanied by pain: acute osteoarthritis, ankylosing spondylitis, chronic polyarthritis, rheumatoid arthritis, radiculitis and osteoarthritis.

The release form of the medicine is tablets.

Revmart tab 15mg x 10
Revmart tab 15mg x 20
Revmart tab 7.5 mg x 20

Paracetamol

Analgesic non-narcotic drug used for mild or moderate pain: headache (including migraine), dental. Also used for sore throat, myalgia and neuralgia.

The drug reduces temperature for colds and various infectious diseases.

The drug relieves symptoms for the duration of its action, but does not affect the development of the disease.

Paracetamol tab 0.5 x 20

Weldexal

Tablets and solutions are prescribed for acute and chronic forms of inflammatory diseases, metabolic and inflammatory-degenerative pathologies of the musculoskeletal system. Relieves pain of various origins: after surgery, dental pain, with metastases in bone tissue, during menstruation, radiculitis, renal colic, sciatica, neuralgia.

This is a symptomatic remedy that does not affect the progression of the disease.

Weldexal tablet. p/p/o 25 mg No. 10
Veldexal solution for IV and IM 25 mg/ml 2 ml x 5

Ketoprovel

Symptomatic medicine in tablet form. Relieves inflammation and pain in radiculitis, rheumatoid and seronegative arthritis, osteoarthritis, bursitis, cancer, neuralgia, tendonitis, algodismenorrhea, myalgia. Helps with toothache and headaches, as well as pain symptoms after injuries and operations.

Ketoprovel tab 100 mg x 20

Ketorolac

Anti-inflammatory, analgesic drug with antipyretic effect.

Used for severe or moderate pain after injuries, operations, oncology, arthralgia, radiculitis, dental diseases, neuralgia.

Prescribed for symptomatic therapy.

Ketorolac tab 10 mg x 20
Ketorolac amp 30mg 1ml No. 10

Aponil

Used against inflammation, pain, elevated body temperature. Selectively inhibits COX-2, acting directly on the site of inflammation. Fights pain, fever and inflammation of the musculoskeletal system.

Aponil tab 100 mg x 20

Aceclofenac

The symptomatic drug is used as part of complex therapy for inflammatory diseases of the musculoskeletal system, to relieve pain in glenohumeral periarthritis, rheumatism, and dental diseases. The product reduces joint swelling and eliminates morning stiffness.

Aceclofenac Welfarm tab p/p/o 100 mg x 20

Acetylsalicylic acid

The product fights pain, fever, inflammation. Blocks the production of thromboxane A2, inhibiting platelet aggregation. Helps with mild to moderate pain.

Prescribed for adults and children over 15 years of age.

Acetylsalicylic acid 500 mg x 20
Acetylsalicylic acid 500 mg x 20 R

Diclogen

The drug is used for short-term treatment of moderate pain in diseases of the musculoskeletal system, after operations and injuries, in diseases of the pelvic organs, as well as neuralgia and algodismenorrhea.

Diclogen amp 25mg/3ml x 5

How to take Wobenzym?

Maintenance intake of the drug becomes 3 or 5 tablets. 3 times/day. The tablets should be taken half an hour before meals with water. The doctor selects the course of use and dosage depending on the severity and duration of the disease.

During antibiotic therapy, to prevent adverse reactions, Wobenzym is prescribed in a dose of 5 tablets. 3 rubles/day. The medication must be taken during the period of antibiotic therapy. To regulate intestinal flora after taking antibiotics, Wobenzym is taken for 2 weeks, 2-3 tablets. 3 rubles/day. Prophylactic dose 2-3 tablets. 3 rubles/day, course 1.5 months, which is repeated periodically. Wobenzym as a “cover” for chemotherapy and radiation therapy is taken 3-5 tablets. 3 rubles/day during the entire course of therapy.

Wobenzym for immunity

Reviews from doctors and patients confirm the beneficial effects of Wobenzym on the body. The use of an immunomodulator increases resistance to diseases and accelerates the onset of recovery.

The popularity and demand of Wobenzym are associated with its composition. Wobenzym is a preparation of natural, plant origin.

Product components:

  • normalize the functioning of the immune system;
  • stop inflammatory and other negative processes;
  • prevent and minimize swelling;
  • help in the fight against blood clots, dissolving them;
  • eliminate pain;
  • activate antitumor protection.

Doctors note that most problems with immunity are associated with prolonged exposure to stressful situations, depression, overwork, poor nutrition and poor lifestyle. Therefore, taking Wobenzym must be combined with the correction of life and the elimination of provoking factors.

Wobenzym belongs to the enzyme therapy group of drugs. Enzymes (enzymes) are specific proteins that accelerate biochemical reactions in the body. The uniqueness of Wobenzym is due to the targeted fight of enzymes against pathological processes.

Popular questions about Wobenzym

Why is Wobenzym better in comparison with analogues?

With long-term treatment using increased doses of the drug, no adverse reactions were identified. Wobenzym is well tolerated. Does not affect concentration, does not inhibit mental and physical reactions. The drug has high effectiveness and safety.

What is Wobenzym from?

The drug is taken in complex therapy: (in urology, gynecology, surgery, traumatology, angiology, endocrinology, ophthalmology, cardiology, pulmology, gastroenergology, nephrology, pediatrics).

How to take Wobenzym?

Depending on the duration of the disease, the number of tablets ranges from 3 to 10 at a time. One of the important points of taking the drug is that enzymes should not come into contact with food. Therefore, the intake should be 30-40 minutes before a meal, or 2 hours after a meal. Do not chew the tablets under any circumstances.

Where can I buy Wobenzym?

You can buy Wobenzym in our online pharmacy 911 at the most affordable prices in Ukraine. We try to maintain the lowest prices and high quality for popular medications.

Prices for the drug and its analogues

The cost of Wobenzym analogues varies in different price segments and directly depends on the country of origin. Russian-made drugs are cheaper than foreign analogues:

Name of the medicineActive ingredient dosage (mg)Number of pieces per packageAverage price in rubles
Wobenzym25040
200

800

452-460
1759-1768

5928-5937

Longidaza (lyophilisate for solution for injections)
Longidaza suppositories (rectal and vaginal)
3000 IU
3000 IU
5
10

20

1896-1920
1733-1750

3063-3080

Ronidaza510191-228
Evenzim40030226-244
Serox101085-101
Acidin-Pepsin100050200-250
N-Zim4500 units10450-500
Fibrinase1010375-400
Movinase1010150-200
Serrata1030250-300

Note!

The description of the drug Wobenzym on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.

The role of the immune system in human life

The human immune system is represented by groups of regional lymph nodes, bone marrow, spleen and thymus. These are the main organs. Auxiliary in the system are the adenoids, lingual and cervical tonsils, appendix, and thoracic lymphatic duct.

Together they perform the following functions:

  • protection from harmful microorganisms entering from the external environment and developing inside the body;
  • control of pathological changes in cells;
  • suppression of malignant cell division.

The causes of problems with immunity can be ignoring the rules of personal hygiene, attacks by viruses, fungi, parasites and microbes, and chronic diseases.

Failure of the immune system negatively affects the functioning of all internal organs and leads to the degeneration of healthy cells into cancerous ones. Protective functions can be restored with the right lifestyle and taking immunomodulatory drugs. These include Wobenzym. The principle of action of the medicine is to supply substances produced by the organs of the immune system. As a result, the protection is enhanced, which is important when natural immunity decreases.

Advantages and disadvantages of Belarusian generics

The most popular among patients are the following Belarusian generics of Wobenzym:

  1. Acidin-pepsin. A budget alternative to Wobenzym, it costs 200-250 rubles. The active component of the drug is pepsin. Due to it, the medicine stimulates digestion and increases the effectiveness of the local protective barrier in the stomach.
  2. N-winter. Belongs to the middle price category. The active component is pancreatin. It helps restore the functioning of the gastrointestinal tract after inflammatory processes and exacerbation of chronic diseases. N-zim is prescribed by a doctor and requires compliance with the treatment regimen, since it has contraindications.
  3. Lidaza. The drug is presented in the form of a solution for intramuscular injection. The cost of Lidaza is 2 times more than Acidina. In medicine, the drug is widely used during the recovery period of patients after surgery. The Wobenzym analogue is effective in healing scars and traumatic ligament damage. The medicine is prohibited for use in oncology and tuberculosis.

Initially, Wobenzym and its generics were perceived as a panacea. The creation of immunomodulators seemed to make it possible to defeat any ailment. However, it turned out that the drugs are addictive.

By receiving enzymes from the outside, the body stops producing its own. Therefore, it is recommended to take immunomodulators strictly as prescribed, taking breaks between courses.

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