Instructions for use of Noben, reviews about the drug and what it is prescribed for

There are restrictions during pregnancy

Has restrictions when breastfeeding

Has limitations for kidney problems

Nootropic drugs are widely used in medical practice for the treatment of various pathological conditions that arise against the background of cerebral circulation disorders. Among such drugs, Noben is especially popular, which, according to the instructions for use, is effective for organic lesions of the central nervous system and emotionally labile disorders of various etiologies.

Packaging of the drug Nooben

Pharmacodynamics

Improves metabolic processes in the brain by activating the synthesis of glucose and ATP, improving blood supply and oxygenation of brain tissue, and promoting the elimination of lactates. Being an antioxidant, it slows down lipid peroxidation and thereby protects the membranes of neurons and mitochondria from damage.

It has nootropic properties with a psychostimulating effect and neuroprotective effect. From the first days of taking the drug, antiasthenic, psychostimulating and antidepressant effects are manifested. Nootropic and mnemotropic effects are observed after 20–25 days of treatment.

General information about the drug Noben

The drug Noben is a medicine that is used for disorders of the brain. It is produced by Russian pharmaceutical companies and OJSC Moskhimfarmpreparaty im. N. A. Semashko.”

Drug group, INN, scope of use

This drug belongs to the drug group nootropics (neurometabolic stimulants). Such drugs influence the higher mental functions of a person.

The international nonproprietary name of a drug is determined by the content of the active substance in it, which affects the human body in one way or another.

INN Nobena – Idebenon. The scope of application of the drug is psychiatry and neurology. It is prescribed to patients with impaired memory, mental activity, and asthenic syndrome, which is caused by deterioration of cerebral circulation.

See also:

Instructions for use of the Nootropic drug, indications, contraindications and reviews

Release form, cost

The drug is available in the form of capsules for oral use. The outer shell of the capsule consists of gelatin, inside which contains granular powder of orange or yellow color with white or orange inclusions. The capsule itself is hard and yellowish in color. Capsules are contained in plastic cell blisters of 10 pieces. A cardboard box contains from 10 to 120 capsules.

The cost of the drug is determined by the number of capsules in the package, the manufacturer, and the place of purchase. Examples of prices in different pharmacies in large Russian cities:

Compound

One capsule of Noben contains:

• active ingredient – ​​idebenone (30 mg);
• auxiliary components – potato starch (about 40 mg), cellulose (20 mg), lactose (102 mg), magnesium stearate, povidone;
• capsule shell (consists almost entirely of gelatin, there is also a small amount of titanium dioxide and yellow dyes).

Pharmacodynamics and pharmacokinetics

Pharmacodynamics depend on the action of the active component of the drug - idebenone. The main purpose of such a substance is to normalize metabolic processes in the brain, which is carried out by activating the production of glucose and ATP, improving the supply of brain structures with oxygen and nutrients. In this case, the following actions are observed:

• nootropic;
• antioxidant (slowing lipid oxidation, preventing neuronal damage);
• mnemotropic (effect on memory and learning);
• psychostimulant;
• antiasthenic;
• antidepressant.

The first results are noticeable from the first days of taking the drug. A pronounced nootropic effect develops within 3 weeks of regular use.

Pharmacokinetic features of idebenone:

• rapid absorption from the digestive tract;
• the highest concentration in the blood occurs 4 hours after ingestion;
• penetrates the blood-brain barrier, after which it is distributed in the tissues and structures of the brain;
• does not accumulate in the body even with prolonged use;
• the metabolic process occurs in the liver;
• excreted along with urine and feces;
• half-life lasts about 18 hours.

Indications

psychoorganic syndrome caused by cerebral circulation disorders and age-related involutional changes in the brain;

cerebroasthenic disorders of vascular, traumatic, psychogenic (neurasthenia) and combined etiology, manifested in the form of: memory and/or attention impairments, decreased intellectual productivity and general activity, emotional instability, asthenic, asthenic-depressive and moderately severe depressive states, headaches, dizziness , tinnitus.

Why Noben is prescribed and contraindications to its use

This medicine has special indications. Among them:

1. Organic lesions of the central nervous system.
2. Cerebrovascular insufficiency associated with deterioration of blood circulation in the brain (including due to age-related changes).
3. Cerebrasthenic syndrome. Most often it develops against the background of a vascular, psychogenic or post-traumatic disorder of the brain and is manifested by the following pathological conditions:

• deterioration of the memorization process;
• inability to concentrate;
• deterioration of mental activity;
• emotional instability;
• general impotence;
• depression;
• development of dizziness and headaches, tinnitus.

1. Emotionally labile disorders.

The drug is also prescribed for the treatment of Alzheimer's disease (senile dementia). Many years of experience in using Noben for this pathology testifies to its effectiveness.

The drug is not recommended for use in the presence of the following contraindications:

• individual intolerance to the active substance or auxiliary components (for example, lactose);
• severe renal dysfunction.

Due to the lack of clinical data on the safety and effectiveness of Noben for children, it is prohibited for use in pediatric practice.

The drug can be prescribed to pregnant and lactating women. But this must be done with caution and only if the expected benefit is higher than the possible risk to the child.

See also:

Instructions for use of the drug Noopept, indications, reviews from patients and doctors

Similar means

There are many products that can replace Noben. Many of them have similar nootropic effects, but are much cheaper. The best analogues of Noben:

1. Vinpocetine. A medicine produced by Biocom from Russia. Release form: tablets for oral administration containing 5 mg of vinpocetine. The drug is intended to improve blood circulation in the brain. It is also used for visual and hearing impairment.
2. Gopantam. Another inexpensive domestic nootropic and psychostimulant. It also has an anticonvulsant effect, so it is often prescribed for tremor, epilepsy, neuroleptic syndrome and parkinsonism.
3. Bilobil. A well-known herbal medicine from Slovenia (Krka), which contains extract of the leaves of the ginkgo biloba plant. Available in the form of capsules used for memory impairment and decreased intellectual abilities.
4. Idebenon, Celestab. Structural analogues of Noben. They have identical composition and have the same indications, contraindications and side effects.

Any drugs that affect the brain and mental activity are prescribed by the attending physician individually for each patient. Self-medication can lead to negative consequences.

See also:

Instructions for use of Nootropil, reviews, indications and contraindications for use

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Instructions for use of Noben tablets

When using the medicine, it is important to follow some recommendations. Among them:

1. Capsules are intended for oral administration. They are drunk whole, washed down with a sufficient amount of liquid.
2. The best time to take is after a meal.
3. The dosage regimen is determined by the attending physician. As a rule, an adult patient is prescribed 1 capsule twice or thrice a day.
4. It is not recommended to take the drug after 17.00 (that is, the last dose should be taken before this time).

The duration of the therapeutic course is usually about 6-8 weeks. Such courses are carried out several times a year (depending on the severity of symptoms) - 2 or more.

This drug practically does not interact with other medications.

Side effects, overdose symptoms

Noben is well tolerated by most patients. In rare cases, side effects occur. It can be:

• sleep problems (insomnia, difficulty falling asleep, deterioration in sleep quality);
• headaches, dizziness;
• excessive mental excitability;
• allergic reactions (redness and itching of the skin, rashes, urticaria);
• disruption of the upper digestive system, which is accompanied by a feeling of heaviness and pain in the stomach, nausea, bloating, and heartburn.

In case of overdose, increased side effects are observed. In this case, the first thing to do is to take sorbents. Symptomatic therapy is also indicated.

The drug is not recommended to be taken while driving a vehicle, or for people whose work requires quick motor and mental reactions.

Reviews about the drug

Reviews of doctors and patients who have used it will help you understand the advantages and disadvantages of the drug.

Opinion of neurologists

Most neurologists speak positively about this medication:

Lavrentiev A.N., neurologist with 16 years of experience: “A very good remedy. I prescribe it to patients who complain of problems with memory, thinking and other disorders of the functioning of the brain. The drug stimulates blood supply to the brain, improves its functioning, and prevents oxygen starvation. Another positive effect is its antidepressant effect. Yes, the medicine is expensive, even though it is produced in Russia. It is also important to pay attention to contraindications - it should not be taken by those with hypersensitivity to idebenone, renal failure, as well as children under 18, pregnant and lactating women. The dosage and course of treatment should be determined by the attending physician, depending on the severity of the symptoms and the general condition of the patient.”

Kapulov P.V., neurologist: “I definitely recommend Noben. This is simply an indispensable remedy for people with cerebrovascular accidents. It also helps alleviate the negative symptoms of a serious illness – Alzheimer’s disease.”

Reviews from those who took Noben

Vadim, 31 years old: “I took Noben for about 2 months. The doctor prescribed this medicine to me to improve memory and stimulate brain function. Helped me. There were no adverse reactions. I recommend".

Karina, 26 years old: “My mother-in-law suffered from headaches and constant nervous tension for a long time. She herself is very emotional and impulsive. My husband and I spent a long time trying to persuade her to see a doctor. She gave up. The neurologist prescribed Noben for her. The medicine is quite expensive, but very effective. After only a week of taking it, her headaches disappeared, she stopped being nervous and worrying about trifles. In general, it helped us all.”

Noben is a popular domestically produced nootropic drug. It is used to eliminate negative symptoms (problems with memory and concentration, impaired mental activity) that arise against the background of worsening blood circulation in the brain.