Pharmacodynamics and pharmacokinetics
Septefril tablets are used in the treatment of throat diseases . As is known, decamethoxin is part of the group of ammonium compounds with a strong antiseptic effect. By acting on microbial cells on the surface of the mucous membranes, this substance changes their permeability.
Decamethoxin is characterized by a wide spectrum of antimicrobial action, including inhibition of corynobacteria diphtheria , pyogenic cocci, for example: protozoa , yeast-like fungi, dermatomycetes and viruses . Treatment with Septefril slows down the formation of decamethoxin-resistant forms of microorganisms.
When using the drug in complex therapy, an increase in the effect of other antimicrobial agents was noted. Septefril has a bactericidal, fungicidal, and sporicidal effect on microbial cells. The maximum effectiveness of the tablets occurs 7-10 minutes after taking and lasts for at least an hour.
Septefril-Darnitsa
This form of the drug belongs to bi-quaternary ammonium compounds. Its chemical structure and antimicrobial action is close to that of aethonium . The effectiveness of Septefril-Darnitsa is also manifested against: diphtheria bacillus, pyogenic cocci, protozoan yeast-like fungi, dermagomycetes and viruses, acting bactericidal, sporicidal and fupgicidal.
The effect of this drug on 200 strains of diphtheria bacilli is especially noted, showing maximum neutralizing effect. The tablets increase the sensitivity of bacteria to various antibiotics without inhibiting the body’s immunological reactivity.
When are Septefril tablets prescribed?
The drug is used in the complex treatment of diseases in which the oral cavity, pharynx and larynx become inflamed under the influence of microorganisms:
- gingivitis, periodontitis and stomatitis,
- candidiasis, which affects the mucous membrane in the mouth,
- pharyngitis, laryngitis, tonsillitis and tonsillitis.
Doctors prescribe sanitation with medication to patients who are carriers of pathogenic microbes: staphylococci, diphtheria bacillus and varieties of candida. The medicine is used to treat the oral cavity, pharynx and nasopharynx.
The drug is used for antimicrobial prevention of complications that arise after surgical operations in the mouth and pharynx.
Septefril for angina is prescribed at the initial symptoms of the disease to eliminate inflammation, redness and swelling of the throat and prevent the development of bacterial complications.
Reduction in pain when swallowing occurs ten minutes after taking the medicine.
Septefril for stomatitis is absorbed according to the application regimen to reduce swelling, pain and accelerate the healing of ulcerations in the oral mucosa. The medication shortens the duration of infection to four days.
Indications for use
The main indications for the use of Septefril tablets are:
- prevention and treatment of diseases in the oral cavity and pharynx with stomatitis, sore throat, tonsillitis, pharyngitis and so on;
- sanitation of carriers of diphtheria bacillus, pathogenic staphylococcus, mucous membrane and pharynx;
- prevention of infectious complications before and after surgical interventions, dental procedures in the oral cavity and nasopharynx.
Septefril tablets 0.2 mg No. 10x5
Product description
Septefril.
Release forms
Pills.
INN
Decamethoxin.
FTG
Antifungal agent.
general characteristics
Basic physicochemical properties: round tablets with a flat surface, beveled edges and scoring, white or almost white.
Compound
Active ingredient: 1 tablet contains decamethoxin - 0.2 mg; excipients: sucrose, povidone, potato starch, calcium stearate.
Pharmacotherapeutic group
Other antiseptics used to treat throat diseases. ATC code R02A A20.
Indications for use
Local treatment as part of complex therapy for diseases of the oral cavity and pharynx (stomatitis, gingivitis, pharyngitis, tonsillitis).
Contraindications
Hypersensitivity to decamethoxin or other components of the drug; During pregnancy and breastfeeding; children under 18 years of age.
Precautionary measures
Before starting treatment with Septefril, you should consult your doctor! Do not use the drug for longer than prescribed without consulting your doctor. If the signs of the disease do not begin to disappear, or, conversely, the health condition worsens, or adverse events appear, you should stop taking it and consult a doctor regarding further use of the drug. The drug contains sucrose. Each tablet contains 786.0 mg of sucrose, which corresponds to 0.0655 bread units (XU). Caution should be exercised in patients with diabetes mellitus. Patients with rare hereditary diseases such as fructose intolerance, impaired glucose-galactose metabolism or sucrase-isomaltase deficiency should not take this medicine. Due to the sucrose content, it may cause damage to teeth with long-term use. It is not recommended to use for more than 1 week. When used for more than 7 days, imbalances in the microflora of the pharynx may occur. To increase the concentration of the drug in saliva during the resorption of the drug, you should refrain from frequent swallowing of saliva. It is undesirable to use the drug simultaneously with different types of rinsing the mouth and pharynx.
Use during pregnancy or breastfeeding
There are no clinical data on the use of Septefril during pregnancy or breastfeeding. The drug should not be used by pregnant women. If it is necessary to use the drug, breastfeeding should be discontinued.
The ability to influence the reaction rate when driving a vehicle or working with other mechanisms
Does not affect. Children There is no clinical experience on the safety and effectiveness of the drug Septefril in children under 18 years of age.
Interaction with other drugs
If you are taking any other medications, be sure to tell your doctor! With simultaneous use of the drug with antibiotics and systemic antimicrobial agents, the antibacterial effect of the drug is enhanced.
Directions for use and dosage
After preliminary rinsing the mouth, keep the tablets in the mouth until completely absorbed. For adults, take Septefril 1 tablet 4-6 times a day. The duration of the course of treatment is determined by the doctor, taking into account the characteristics of the disease, tolerability of the drug and the achieved effect. The drug should be taken after meals, then you should refrain from eating and drinking for 1 hour. Use in pediatrics There is no clinical experience on the safety and effectiveness of the drug in children under 18 years of age.
Overdose
There have been no reports of cases of overdose with Septefril. In case of overdose of the drug, you should immediately seek medical help!
Side effect
Allergic reactions, incl. skin rashes, skin itching. Hypersalivation is possible, which disappears after resorption of the tablets. If the described adverse effects occur or other unusual reactions not mentioned in the package insert occur, you should stop taking the drug and consult your doctor about its further use.
Best before date
3 years. The drug should not be used after the expiration date indicated on the package.
Storage conditions
At a temperature not exceeding 25°C. Keep out of the reach of children.
Package
10 tablets in contour-free packaging. 10 tablets in a blister made of polyvinyl chloride or polyvinylidene chloride film and aluminum foil with thermovarnish coating on one side and printing on the other side. 5 blisters, together with instructions for medical use of the drug or an insert, are placed in a cardboard pack.
Vacation category
Over the counter.
Buy Septefril tablet. d/rac. 0.2 mg in blister pack No. 10x5 in the pharmacy
Price for Septefril tablet. d/rac. 0.2 mg in blister pack No. 10x5
Instructions for use for Septefril tablet. d/rac. 0.2 mg in blister pack No. 10x5
Analogs
Level 4 ATC code matches: Patentex Oval N
Nonoxynol
Erotex
Benatex
NuvaRing
Pharmatex
The following drugs have a similar effect: Hexicon, Faringosept, Miramistin, Decathylene and others.
Note!
The description of the drug Septefril on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.
Reviews of Septefril
It should be noted that reviews of Septefril are mainly found on Ukrainian forums. Moreover, these tablets are often used for children and pregnancy . However, the effectiveness of this drug is not evident in all cases.
When this medicine is used for severe redness and sore throat, lozenges alone are clearly not enough. In such cases, patients doubt whether the treatment has been prescribed to them correctly and what the pills help best with.
As you know, if a sore throat is not treated in a timely manner, complications may quickly develop, for example, sore throat . Therefore, when buying tablets for children, you need to remember the whole complex of treatment: rinsing the nose, rinsing and irrigating the throat. More complex cases require taking medications, but only as prescribed by a doctor.
Features of application.
The drug contains sucrose, so patients with diabetes should use the drug with caution; patients with hereditary intolerance to fructose, glucose-galactose, sucrose-isomaltose should not use the drug.
When used for more than 7 days, imbalances in the microflora of the pharynx may occur.
To increase the concentration of the drug in saliva during the resorption of the drug, you should refrain from frequent swallowing of saliva.
It is undesirable to use the drug simultaneously with different types of rinsing the mouth and pharynx.
Septefril price, where to buy
In Russian online pharmacies the drug can be purchased for 21-25 rubles.
The price of Septefril in Ukraine varies between 1.8-2.5 UAH.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
LuxPharma* special offer
- Septefril tab.
0.2 mg N40 RUR 980 order
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Pharmacy24
- Septefril Darnitsa 0.2 mg No. 20 tablets PrAT" Pharmaceutical company "Darnitsa", Ukraine
16 UAH. order - Septefril 0.2 mg No. 10 tablets TOV "Agrofarm", Ukraine
4 UAH order
- Septefril 0.2 mg No. 10 tablets PrAT” Pharmaceutical company “Darnitsa”, Ukraine
6 UAH order
Frequently asked questions about Septefril
What does Septefril help with?
The medicine is used in the treatment and prevention of complications in diseases that are accompanied by bacterial inflammation in the throat and mouth.
Seprefril, how to take correctly?
Before taking the medication, the patient rinses his mouth, then dissolves one tablet in his mouth until the active substance dissolves - four to six times a day. The medication is taken after meals, because then you cannot drink or eat for 60 minutes. The course of therapy is one week.
How quickly does Septefril help?
Relief from pain when swallowing occurs seven to ten minutes after taking the medicine.
Septefril, is it possible for children?
Septefril is not prescribed to children, since the instructions do not contain information about clinical studies and the safety of administration to small patients.
