Abisil – description of the drug, instructions for use, reviews

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Manufacturers: Tatkhimfarmpreparaty OJSC, Moscow Pharmaceutical Factory (Russia)

Active ingredients

  • Not indicated. See instructions

Disease class

  • Otitis externa, unspecified
  • Otitis media, unspecified
  • Inflammation and blockage of the auditory [Eustachian] tube
  • Acute nasopharyngitis (runny nose)
  • Acute sinusitis
  • Acute pharyngitis, unspecified
  • Acute laryngitis and tracheitis
  • Chronic rhinitis
  • Chronic pharyngitis
  • Chronic sinusitis
  • Chronic diseases of the tonsils and adenoids
  • Chronic laryngitis and laryngotracheitis
  • ingivitis and periodontal diseases
  • Periodontal disease
  • Alveolitis of the jaws
  • Stomatitis and related lesions
  • Cellulitis and oral abscess
  • Skin abscess, boil and carbuncle
  • Pyoderma
  • Decubital ulcer
  • Erysipelas
  • Presence of dentures
  • Open wound of an unspecified area of ​​the body
  • Unspecified complication of surgical and therapeutic intervention
  • Post-traumatic wound infection, not elsewhere classified
  • Frostbite involving multiple areas of the body and unspecified frostbite
  • Thermal and chemical burns of unspecified localization

Clinical and pharmacological group

  • Not indicated. See instructions

Pharmacological action

  • Anti-inflammatory
  • Analgesic (non-narcotic)
  • Regenerating and reparative
  • Antibacterial

Pharmacological group

  • Other non-narcotic analgesics, including non-steroidal and other anti-inflammatory drugs

Solution for topical use Abisyl

Instructions for medical use of the drug

Description of pharmacological action

The drug has a pronounced anti-inflammatory, wound-healing, antibacterial, analgesic, and anti-exudative effect due to the properties of the natural terpenoids included in its composition. It has a wide spectrum of antimicrobial activity against gram-positive and gram-negative bacteria, incl. and to antibiotic-resistant strains. Creates optimal conditions for the healing of the wound surface of soft tissues, accelerates the process of epithelization, and improves microcirculation. When applied topically, it is not absorbed and does not have a local irritating effect. The drug does not have toxic properties, no teratogenic, mutagenic or carcinogenic effects have been identified, which allows its use in all age groups

Indications for use

In general surgical practice: purulent-inflammatory diseases of the skin and soft tissues (trophic ulcers and long-term non-healing purulent postoperative and post-traumatic wounds, fistulas, bedsores, burns and frostbite, abscesses and phlegmons, including the maxillofacial area). In otorhinolaryngology: otitis media; eustachitis; sinusitis; rhinitis; nasopharyngitis; pharyngitis; laryngitis; tonsillitis; conditions after tonsillectomy. In dentistry: stomatitis; periodontal disease; gingivitis; alveolitis; complications during dental prosthetics. In dermatology: erysipelas; pyoderma.

Release form

Oil solution for local and external use, 100 g; dark glass bottles of 5, 10, 15, 20, 30 and 50 ml or dropper bottles of 15, 20 or 25 ml; in a cardboard pack 1 bottle or dropper bottle.

Pharmacodynamics

The drug has a pronounced anti-inflammatory, wound-healing, antibacterial, analgesic, and anti-exudative effect due to the properties of the natural terpenoids included in its composition. It has a wide spectrum of antimicrobial activity against gram-positive and gram-negative bacteria, incl. and to antibiotic-resistant strains. Creates optimal conditions for the healing of the wound surface of soft tissues, accelerates the process of epithelization, and improves microcirculation. When applied topically, it is not absorbed and does not have a local irritating effect. The drug does not have toxic properties; no teratogenic, mutagenic or carcinogenic effects have been identified, which allows its use in all age groups.

Contraindications for use

Individual intolerance.

Side effects

A short-term burning sensation at the site of application of the drug. Persons with hypersensitivity to essential oils may experience allergic reactions.

Directions for use and doses

Locally, externally. Shake before use! For purulent-inflammatory diseases of the skin and soft tissues, surgical treatment of the wound surface is first performed and then the drug is applied 1-2 times a day in an even thin layer. The duration of treatment depends on the form and severity of the disease (usually 5–10 days) and ends when fresh granulations, epithelial islands or complete epithelialization appear. In case of inflammatory processes in the maxillofacial area, after opening and surgical treatment of abscesses and phlegmons, tampons soaked in Abisil solution are inserted into the pockets and postoperative wounds. The procedure is repeated daily for 5–7 days. For diseases of the oral cavity, treat the affected surface of the mucous membrane 2-3 times a day or use turundas moistened with the drug. For otitis media, insert a swab moistened with the drug into the external auditory canal. When treating rhinitis and sinusitis, instill 1-2 drops into each nasal passage 3-4 times a day. For sinusitis, the drug is administered into the maxillary sinus after its preliminary sanitation. When treating tonsillitis and other inflammatory diseases of the throat, treat the mucous membranes with the drug 2-3 times a day. For skin diseases, the drug is applied 1-3 times a day in a thin layer to the affected areas. The duration of the course is individual and depends on the severity of the disease.

Interactions with other drugs

Should not be combined with other external agents.

Special instructions for use

Avoid contact of the drug with the conjunctiva of the eye; if contact occurs, rinse the eye with water. Should not be applied to wet skin.

Storage conditions

In a dry place, protected from light, at a temperature not exceeding 25 °C.

Best before date

4 months

ATX classification:

D Dermatotropic drugs

D08 Antiseptics and disinfectants

D08A Antiseptics and disinfectants

D08AX Other antiseptics and disinfectants

Every year the onset of autumn is accompanied by an outbreak of colds. Acute respiratory viral infections (ARVI) and influenza are the most widespread infectious diseases and cause significant damage to human health and the economy of large cities. In addition, the problem of acute respiratory diseases (ARI) in pediatrics is of particular relevance, since in the structure of the overall primary morbidity of children, respiratory infections account for the largest number of cases than all other diseases combined. Acute respiratory infection (ARI) is associated with about 90% of visits to a doctor in the autumn-winter period.

Traditionally, during the period when the epidemic threshold for colds increases, children are the main source of the spread of influenza infection in society, because Most parents continue to take their children to kindergartens and schools during the initial manifestations of a cold, without paying due attention to it. In addition, children living in large cities belong to the so-called “high risk” group in terms of the prevalence of respiratory tract infections. And also, in young children (from 0 to 3 years), a respiratory infection, especially influenza, quite often leads to the development of bacterial complications in the form of pneumonia, bronchitis, acute and otitis media. As a result, the prevention of colds in the autumn-winter period is especially relevant, both for young children and older children attending kindergartens and schools. And therefore, experts recommend paying special attention to the herbal drug Abisil, which has a wide spectrum of action: anti-inflammatory, antibacterial and immunomodulatory activities. So why should special attention be paid to the drug Abisil.

1. Abisil - a means of preventing disease

As is known, in relation to viral respiratory infections we are usually talking about nonspecific prevention(5) and symptomatic therapy, since specific etiotropic therapy (elimination of the causes of the disease), as well as specific immunoprophylaxis or vaccination, are currently possible only in relation to influenza viruses, which account for only 5–15% of ARVI(1).

The main active ingredient of the drug Abisil is Siberian fir terpenes. It should be noted that these substances are formed in nature during the life of coniferous plants to protect against harmful environmental influences and have a wide range of pharmacological effects: antimicrobial, anti-inflammatory, immunomodulatory, wound healing, analgesic and affect different types of pathogens. That is why experts recommend the use of the drug Abisil both during the period of prevention and during the period of increasing the threshold of seasonal colds and their complications. It has a general healing effect, increases the tone and protective properties of the body and is therefore necessary in treatment at the early stage of cold symptoms in order to prevent further development of the disease.

How can you use Abisil:

To prevent colds and during periods of increased epidemic threshold, it is necessary to treat the nasal mucosa 1-2 times a week. Course from 1 to 3 months. This procedure will have a stimulating effect on the nervous and immune systems, increase the body’s overall defenses, and reduce the risk of developing further complications (4).

In addition, the drug can be used in the form of inhalations. To do this, you need to dissolve 8-10 drops of the drug in 500 ml of hot water and inhale using an inhaler for 10-15 minutes or inhale the drug directly from the bottle or when applied to a cotton swab or paper napkin (3).

To prevent influenza and acute respiratory infections in organized groups, as well as at home, you can use the method of phytoaeration of air with terpene vapors through special sprayers.

It should be noted that the assessment of the preventive effectiveness of the drug Abisil was studied during an influenza epidemic among children attending preschool institutions. Based on the results of the preventive use of the drug Abisil, data were obtained on a decrease in the number of sick children in the younger group (3-4 years) - by 17.9%, in the middle group (4-5 years) - by 12.5%, in the older group (5- 6) – by 12.2%. In none of the cases of using the drug Abisil were there any general or local adverse reactions. The study allowed us to conclude that the drug Abisil has a pronounced preventive effect and safety when used intranasally, by administering the drug through the nasal mucosa in preschool children (2).

2. Abisil - a medicine for symptomatic therapy

If infection with a virus and the disease does occur, then, as a rule, attempts to stop all manifestations of the disease with appropriate symptomatic remedies are usually fraught with polypharmacy (prescribing several medications at the same time): decongestants, to relieve swelling and congestion of the nasal mucosa; antihistamines (antiallergic); local antiseptics (whose effectiveness against viral infections is generally very controversial); antipyretic and anti-inflammatory drugs, as well as immunomodulatory drugs, is obviously an excessive tactic for a banal ARI. In addition, the need to use 4-6 different drugs at the same time significantly reduces the degree of patient compliance with therapy in terms of taking different drugs prescribed by the doctor and other recommendations and measures for changing lifestyle during the treatment period.

In addition, most traditional regimens for the prevention and treatment of ARVI and influenza also involve the use of expensive drugs of chemical origin, which are often unsafe for the body. Such drugs increase the load on all human organs and systems, already weakened by infection and high temperature, exacerbating the critical condition of the human body. Therefore, specialists, offering patients means for the prevention and treatment of colds, acute respiratory viral infections and influenza, are paying increasing attention to herbal medicines.

How to use Abisil at the first signs of a cold as a symptomatic treatment.

Before and during the epidemic rise of colds, if you have the first signs of illness in the form of rhinitis, in order to prevent further complications of the disease, experts recommend treating the nasal mucosa with Abisil 2-3 times a day or instilling the drug 1 drop into each nostril 1 -2 times a day. The drug strengthens the body's resistance to acute respiratory diseases, improves immunity and helps relieve symptoms, returning you to an active life in a short time.

This issue is especially relevant in the treatment of nasal symptoms of acute respiratory viral infection (acute rhinosinusitis), taking into account the fact that the average therapeutic dose of some synthetic vasoconstrictor drugs is close to toxic, and therefore there is a high probability of overdose and systemic toxic effects from other organs. In addition, important advantages of herbal medicines are the relatively low frequency of adverse reactions, including allergic ones, as well as the complexity of effects aimed at eliminating the pathological process (6).

3. Abisil in the treatment of complications of ARVI

Traditionally, due to the widespread prevalence of ARVI, high morbidity and relatively rare adverse outcomes, we often carry out self-diagnosis and self-medication, seeking medical help only if complications of the disease develop. To prevent the development of complications, Abisil must be used at an early stage of the disease, when the first symptoms appear. But if you were unable to avoid complications, then the timely use of Abisil in this case will significantly ease the course of the disease itself, and will return you to “function” in a significantly short time, because it is indicated for the treatment of complications of colds in the form of infectious diseases of the nasopharynx and respiratory tract, as well as for purulent-inflammatory diseases of the ear: rhinitis, sinusitis, otitis, eustachitis, nasopharyngitis, pharyngitis, tonsillitis, laryngitis and other complicated forms of colds and flu. How to use Abisil in the treatment of complications that have arisen can be found in the “Areas of Application” section.

We should not forget that the cause of complications is often not only viruses, but also bacteria, and a reliable differential diagnosis of viral and bacterial inflammation is not always quickly feasible. This problem becomes especially urgent when the question arises about the need to prescribe antibiotics. The irrational use of antibiotics, their not always controlled dispensing in pharmacies, coupled with self-medication, lead to an increase in the number of resistant strains, and primarily we are talking about those microorganisms that are most often the causative agents of acute respiratory infections. At the same time, the creation of fundamentally new classes of antibiotics, despite the colossal efforts of the pharmaceutical industry, is delayed. For this reason, in recent years, the interest of the world medical community has been focused on the search for alternative antimicrobial substances, including among well-known herbal remedies. It is also important that the development of resistance of pathogens to plant antibacterial components is observed less frequently than to “classical” antibiotics.

4. Multidirectional action of terpenes

Abisil is a medicinal product whose main active ingredient is Siberian fir terpenes. Terpenoid compounds can have analgesic, anti-inflammatory, wound healing, antimicrobial, antiviral, antihistamine, immunomodulatory, antitumor, antispasmodic, and sedative effects. This list of biological properties of terpenoids important for humans is constantly expanding.

Compounds of the terpenoid group obtained from coniferous trees, due to their unique pharmacological properties, are increasingly used in the treatment of various pathological conditions. Analysis of scientific data and our own research characterizes plant terpenoids, and especially those obtained from coniferous trees, as a promising class in terms of natural compounds that are effective in the complex therapy and prevention of acute respiratory diseases. The relatively low toxicity of plant-derived terpenoids and the versatility of their pharmacological effects are important advantages of these compounds (6).

The multidirectional effects of Abisil allow it to be used both as a means of prevention, monotherapy (for processes of mild and moderate severity), and as part of complex therapy of acute respiratory diseases.

5. Safety and ease of use

Abisil is a drug that can be purchased in pharmacies without a prescription. It can be used at any age. In therapeutic doses, the drug is non-toxic and has no side effects. No complications from the use of Abisil were registered; in all cases it was well tolerated.

It is important to remember that preventive measures will allow you to avoid the development of colds and their complications. But if you were unable to avoid colds during the cold season, then make sure that Abisil is in your family “home medicine cabinet” in order to be able to prevent the development of colds at an early stage. It will help both children and parents and, with timely treatment, will prevent further complications of cold infections.

This material is for informational purposes only and cannot serve as a substitute for an in-person consultation with a doctor. Before use, you must read the instructions and/or consult a specialist. There are contraindications.

Bibliography:
Pokrovsky V.I., Briko N.I., Danilkin B.K. Infectious diseases and epidemiology: M.: GEOTAR-Media. - 2007. - 816 p.
Anokhin V.A., Sabitova A.M., Ibragimova A.A. Evaluation of the effectiveness of the drug Abisil in the prevention of influenza and ARVI in preschool children // Journal. Medical. – 2013. – No. 4(5). – pp. 43-44.
Zakirova A.M., Moroz T.B., Rashitov L.F., Fetisova T.G. Experience of using the herbal drug “Abisil” in children with acute bronchitis // Bulletin of modern clinical medicine. - 2017. - T. 10. No. 2. - P. 34-39.
Sabitova A.M., Ibragimova A.A. Principles of drug prevention of ARVI in children's groups // Effective pharmacotherapy. Epidemiology and infections. –2013. – No. 2. – P.14-19.
Lytkina I.N., Volkova N.A. Prevention of influenza and acute respiratory viral infections among epidemiologically significant groups of the population // Attending physician. - 2006. - No. 9. - P. 83-85.
Latzerus L.A., Noskov A.P., Pinigina N.M. Biological activity and clinical effectiveness of the new herbal medicine “Abisil-1” // Modern problems of pediatrics and pediatric surgery: Proceedings of the Siberian-American Scientific and Practical Conference. - Irkutsk, October 7-8, 1998 - Irkutsk: Irkut Publishing House. Univ., 1998 – P.233-238

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** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use the drug Abisil, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.

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** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Abisil is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!

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