Belosalik ointment for external use 40g

Compound

Pharmacodynamics

Belosalik®lotion has anti-inflammatory, antipruritic, anti-edematous, antiallergic, antiproliferative, immunosuppressive, keratolytic, antimicrobial and antifungal effects.

Betamethasone dipropionate is a synthetic corticosteroid that has anti-inflammatory, antiallergic, antipruritic and vasoconstrictor effects. When applied to the surface of the skin, it constricts blood vessels, relieves itching, reduces the release of inflammatory mediators (from eosinophils and mast cells), IL-1 and -2, interferon gamma (from lymphocytes and macrophages), inhibits the activity of hyaluronidase and reduces the permeability of the vascular wall. Interacts with specific receptors in the cytoplasm of the cell, stimulates the synthesis of mRNA, inducing the formation of proteins, incl. lipocortin, mediating cellular effects. Lipocortin inhibits phospholipase A2, blocks the release of arachidonic acid and the biosynthesis of endoperoxides, PGs, and leukotrienes (which contribute to the development of inflammation, allergies and other pathological processes).

Salicylic acid, due to its keratolytic action, cleanses affected areas of scales, promotes the penetration of betamethasone into the skin, maintains the acidic environment of the skin, preventing the development of bacterial and fungal infections.

Belosalik ointment for external use 40g

Compound

1 g of ointment contains:
Active substances: betamethasone dipropionate - 640 mcg, which corresponds to the content of betamethasone - 500 mcg, salicylic acid 30 mg.

Excipients: mineral oil, Vaseline.

Pharmacokinetics

A drug with anti-inflammatory, antipruritic, antiproliferative, antimicrobial and keratolytic effects for external use.

Betamethasone has anti-inflammatory, antiallergic, antiproliferative and antipruritic effects. When applied to the surface of the skin, betamethasone has a rapid and strong effect at the site of inflammation, reducing the severity of objective symptoms (erythema, swelling, lichenification) and subjective sensations (itching, irritation, pain).

Salicylic acid, due to its keratolytic action, cleanses affected areas of scales, promotes the penetration of betamethasone into the skin, maintains the acidic environment of the skin, preventing the development of bacterial and fungal infections.

Contraindications

• Lupus.
• Skin manifestations of syphilis.
• Chicken pox.
• Viral skin infections.
• Skin post-vaccination reactions.
• Open wounds.
• Trophic ulcers.
• Rosacea.
• Acne vulgaris.
• Children up to 6 months (for ointment).
• Hypersensitivity to betamethasone, salicylic acid or any of the auxiliary components of the drug.

Directions for use and doses

The drug is intended for external use.

A small amount of ointment is evenly distributed over the surface of the skin, lightly rubbing. The frequency of use is 2 times a day; in mild cases, a single use is sufficient.

The duration of a continuous course of treatment is usually limited to 3-4 weeks. If a longer course of therapy is necessary, it is recommended to use the drug less frequently, for example, every other day. When treating chronic diseases, treatment should be continued for some time after the disappearance of all symptoms, under the supervision of a doctor, to avoid relapse of the disease.

Repeated courses of therapy are possible throughout the year.

Storage conditions

Store out of the reach of children at a temperature not exceeding 25C.

Best before date

4 years.

special instructions

The ointment is intended for external use only on the skin and/or scalp.

Avoid contact of the ointment with the eyes and mucous membranes.

Long-term use of the ointment on the skin of the face is not recommended due to the possible development of dermatitis such as rosacea, perioral dermatitis, skin atrophy and acne.

Avoid using the drug in the anogenital area.

It is not recommended to use the drug under an occlusive dressing, except when necessary. If fungal or bacterial microflora develops on the skin, additional use of an antibacterial or antifungal agent is necessary.

Use in pediatrics

The use of the drug Belosalik in children should be as short as possible, subject to strict precautions, because in children, there is a danger of systemic absorption of a proportionally larger amount of active components due to the predominance of skin area over body weight and insufficient maturity of the epidermis. The drug should not be used in children under bandages and, especially under plasticized diapers, as this may increase the risk of adverse events.

Conditions for dispensing from pharmacies

Available without a prescription

Side effects

Side effects are usually mild.

Dermatological reactions: possible development of hypersensitivity reactions (itching, burning, hyperemia), rarely - acne-like changes, hypopigmentation, stretch marks, skin atrophy, hypertrichosis, telangiectasia, secondary skin infections.

With long-term continuous use and over large areas of skin: betamethasone can cause systemic adverse reactions associated with suppression of the function of the adrenal cortex.

If a hypersensitivity reaction or adverse reactions develop, the drug should be discontinued.

Use during pregnancy and breastfeeding

The use of the drug Belosalik (in the form of an ointment and/or solution for external use) in pregnant women is allowed in cases where the expected benefit to the mother outweighs the risk to the fetus. In such cases, the use of the drug should be short-term and limited to small areas of the skin.

During breastfeeding, the use of Belosalik is possible according to strict indications, but the drug should not be applied to the skin of the mammary gland before feeding.

Interaction

No clinically significant interactions with other drugs were noted.

Simultaneous use of cosmetic and dermatological products

Impact on the ability to drive vehicles and operate machinery

There is no data on the adverse effects of the drug Belosalik on the ability to drive vehicles and machines.

Side effects

Side effects are usually reversible and mild in nature.

From the skin: hypersensitivity reaction (itching, burning or redness), acne-like changes, hypopigmentation, stretch marks, skin atrophy, hypertrichosis, secondary skin infections.

With long-term continuous uncontrolled use and application to large areas of skin: telangiectasia, systemic manifestations of side effects of corticosteroids or salicylates.

If a hypersensitivity reaction or side effects occur, therapy should be discontinued and consult a doctor.

Belosalik solution for external use fl 100ml

Additional information: Drug type medicinal product

Pharmacological group glucocorticosteroid for local use + keratolytic agent

Suitable for children yes

Active ingredient : betamethasone, salicylic acid

Release form solution for external use

Volume 100

Area of ​​application for skin diseases

Pharmacological action: a drug with anti-inflammatory, antipruritic, antiproliferative, antimicrobial and keratolytic effects for external use

Indications for use: subacute and chronic dermatoses, in which therapy with topical corticosteroids is effective, and accompanied by hyperkeratosis and peeling, including: psoriasis, eczema (dyshidrotic, seborrheic, tylotic), neurodermatitis, lichen planus, lichen asbestos, chronic discoid lupus erythematosus, ichthyosis and ichthyotic skin lesions, seborrhea, seborrheic dermatitis (scalp)

Composition 1 g of betamethasone dipropionate 640 mcg, which corresponds to the content of betamethasone 500 mcg, salicylic acid 20 mg, excipients: disodium edetate - 0.3 mg, hypromellose 4000 cps - 5 mg, sodium hydroxide - 5 mg, isopropanol - 392 mg, water - 577.06 mg

The interaction of significant mutual influences of the drug and other drugs during simultaneous use has not been identified; in order to avoid physical incompatibility of various external agents and Belosalik, it is better to apply the lotion at different times with other medications and cosmetics; it has been clinically established that the simultaneous use of products with a drying effect (alcohol-containing products, medical soap, etc.) and the drug may cause skin irritation

Contraindications: skin tuberculosis, skin manifestations of syphilis, chicken pox, viral skin infections, skin post-vaccination reactions, open wounds, trophic ulcers, rosacea, acne vulgaris, children under 6 months of age, hypersensitivity to betamethasone, salicylic acid or any of the auxiliary components of the drug

dosage : a few drops of solution for external use are evenly distributed over the surface of the skin, lightly rubbing, frequency of use is 2 times a day, in mild cases a single use is sufficient; the duration of a continuous course of treatment is usually limited to 3-4 weeks; if a longer course of therapy is necessary, it is recommended to use the drug less frequently, for example, every other day; the drug can be prescribed with caution to children from 6 months and for the shortest possible time

Use during pregnancy in cases where the expected benefit to the mother outweighs the risk to the fetus

Side effects on the skin: possible development of hypersensitivity reactions (itching, burning, hyperemia), acne-like changes, hypopigmentation, stretch marks, skin atrophy, hypertrichosis, secondary skin infections; with long-term continuous uncontrolled use and when applied to large areas of skin: telangiectasia, systemic manifestations of side effects of corticosteroids or salicylates; If a hypersensitivity reaction or adverse reactions develop, the drug should be discontinued and consult a doctor

Overdose with long-term continuous use of a combination of betamethasone and salicylic acid, especially in children, on large surfaces of the skin, when applied to skin with impaired integrity or when used under an occlusive dressing, increased absorption of the active components and the manifestation of systemic effects (secondary adrenal insufficiency, hypercortisolism) cannot be ruled out , Itsenko-Cushing syndrome); treatment: drug withdrawal and symptomatic therapy are recommended

Storage conditions at a temperature not exceeding 25 °C out of the reach of children

Directions for use and doses

Externally.

Bottle with spray nozzle

Belosalik® lotion is sprayed 2 times a day onto the affected areas of the scalp with hair, using a convenient elongated spray nozzle. In some cases, once a day is sufficient.

Before spraying, shake the bottle, place it in a vertical position, then bring the nozzle of the nozzle to the affected area of ​​skin with hair and press the sprayer all the way with your index finger. Apply the required number of sprays to the affected areas of the scalp.

The duration of the course of treatment is individual, as a rule, until the main symptoms of the disease disappear, but is usually limited to 3–4 weeks. If a longer course of therapy is necessary, it is recommended to use the drug less frequently, for example every other day, and consult a specialist.

Dropper bottle

Belosalik® lotion is used 2 times a day. A few drops of lotion are evenly distributed with a cotton swab or fingers over the surface of the skin, lightly rubbing. In some cases, once a day is sufficient. The duration of treatment is usually limited to 3–4 weeks. If a longer course of therapy is necessary, it is recommended to use the drug less frequently, for example every other day, or consult a specialist. Belosalik® lotion can be prescribed to children from 6 months of age with caution and for the shortest possible time.

special instructions

Belosalik® lotion is intended for external use only.

Avoid contact with eyes and mucous membranes, as well as use of the drug in the anogenital area.

It is not recommended to use the drug under occlusive dressings, except when necessary. If fungal or bacterial microflora develops on the skin, additional use of an antibacterial or antifungal agent is necessary.

The drug Belosalik® lotion in the form of a solution for external use is especially convenient for use on the scalp. The solution is easily distributed over the surface of the skin, does not stick or dry out hair, does not leave visible marks, and has a cooling effect on the skin.

Impact on the ability to drive vehicles and machinery. There are no data on the adverse effects of Belosalik® lotion on the ability to drive vehicles and operate machinery.

Belosalic®

If signs of allergic reactions or local irritation appear when using the drug, treatment should be discontinued.

In case of a fungal or bacterial infection on the skin, additional use of an antibacterial and antifungal agent is necessary. Care must be taken to prevent contact with the eyes as cataracts and glaucoma may develop from repeated exposure. If the patient experiences symptoms such as blurred vision or other visual disturbances, it is necessary to consult an ophthalmologist. If the drug accidentally gets into your eyes, rinse them thoroughly with water.

You should avoid getting the drug on the mucous membranes, as well as using the drug in the anogenital area, in areas of extensive skin damage, especially with a violation of the integrity of the skin.

When GCS is used externally, visual impairment is observed, in which case you should consult an ophthalmologist.

Use in children under 12 years of age is possible only under medical supervision.

Children, more than adults, are at risk of suppressing the function of the hypothalamic-pituitary-adrenal system when using local corticosteroids due to the larger ratio of body surface area to body weight and, as a result, increased absorption of the drug. There have been reports of decreased function of the hypothalamic-pituitary-adrenal axis, Itsenko-Cushing syndrome, growth retardation, insufficient body weight gain and increased intracranial pressure in children receiving topical corticosteroids. Inhibition of the function of the hypothalamic-pituitary-adrenal system in children is determined by low plasma cortisol levels and lack of response to stimulation of adrenocorticotropic hormone. Increased intracranial pressure is manifested by protrusion of the fontanelle, headaches, and bilateral papilledema.

When using the drug in children or for the treatment of lesions on the skin of the face, the duration of treatment should not exceed 5 days. The use of the drug under occlusive dressings is not recommended.

With prolonged treatment, when applied to large areas of the skin or when using occlusive dressings, systemic absorption of glucocorticosteroids and salicylic acid is possible.

During long-term treatment with the drug, it is recommended to discontinue it gradually.