Fermencol gel. Instructions for use for scars, scars, stretch marks. Composition, price, analogues

From this article you will learn:

• Fermenkol: patient reviews, price,
• Fermenkol gel - instructions for use using the application method and using the phonophoresis technique.

Fermenkol is a drug based on a complex of proteolytic enzymes (collagenolytic proteases) obtained from marine and freshwater organisms. Fermenkol destroys excessively formed pathological collagen, which makes up hypertrophic and keloid scars.

Indications for use –

• for hypertrophic and keloid scars (Fig. 1-2),
• for scars after acne (Fig. 3),
• to prevent the occurrence of these types of scars.

Release form

The product is produced in the form of a gel for external application, lyophilized powder, and a kit for enzyme correction is available for sale. The gel form is the most popular. It requires no preparation and is immediately ready for application. The powder requires dilution with a special solution, and it is important to strictly follow the indicated dosage.

The enzyme correction kit includes not only the powder, but also a solvent called Solactin. Solactin is a clear liquid that is intended for diluting powder. The result is a homogeneous mass. The powder is available in glass bottles, the volume of each of them is 4 mg. The gel is produced in two variations - 10 mg and 30 mg. Aluminum tube.

The powder can be used independently at home, but this form of release seems inconvenient for many people.

Solactin ensures that the active substances of the drug penetrate into the depths of the scar or scar, so the result from using the enzyme correction kit is most pronounced. It is convenient because it is possible to produce different concentrations of the drug. Depending on the stage of severity of the skin defect, you can select the most effective concentration.

Fermenkol: price, release forms

You can buy Fermenkol in any pharmacy without a doctor's prescription, however, the cost of the drug in different pharmacies varies greatly.

• Fermenkol gel (Fig. 4) – the active substance is a 0.01% complex of proteolytic enzymes, more precisely collagenolytic collagenases (proteases). Auxiliary components: glycerin, ammonium sulfate, methylisothiazolinone, acrylate crosspolymer and water.
  → Fermencol gel price (tube 30 g) – from 1100 to 1500 rubles, → Fermencol gel price (tube 10 g) – from 700 to 900 rubles.

• Fermenkol set (for electrophoresis at home) – the set contains 2 bottles – see Fig. 5. The first contains a yellowish powder, which contains a complex of proteolytic proteases (4 mg). The second bottle contains Solactin, a solvent for preparing a 40 ml enzyme solution, which includes: water, potassium hydroxide, calcium chloride, citric acid and methylisothiazolinone.
  Solactin (compared to saline solution) promotes more efficient penetration of enzymes into the depths of scar tissue. Moreover, using different amounts of solvent to dilute the powder, you can obtain different concentrations of the active components. The manufacturer recommends using a solution concentration of 0.01-0.02% for hypertrophic scars, and 0.05-0.1% for keloid scars.

  
  The prepared solution is used for administration using the electrophoresis method. The latter can be easily carried out at home if you purchase an electrophoresis device intended for home use, for example, “Elfor” (about 3,000 rubles).

Chemical composition

Fermencol gel (the instructions for use contain detailed information about its formula) as an active ingredient includes a set of collagenolytic proteases with molecular weights from 23 to 36. Auxiliary components for different pharmacological forms differ and are presented in the table.

The article provides detailed instructions for using Fermenkol gel.

Solactin solvent consists of citric acid, potassium hydroxide, calcium chloride, hydrochloric acid and purified water.

pharmachologic effect

The instructions for use characterize Fermencol gel as a complex pharmaceutical preparation with a wide spectrum of action. The drug is allowed to be used as monotherapy, as it has proven high effectiveness. In severe cases, it is prescribed in conjunction with other drugs intended to eliminate scars and scars.

Only a dermatologist can prescribe additional medications, having first carefully examined the condition of the epidermis. Fermenkol has a complex effect on the elements of scar tissue. It practically does not affect healthy tissue, since it has a selective, distinct effect on scar tissue.

The drug has collagenolytic activity. This involves breaking down excess collagen in pathological tissue into individual amino acids. Pathological collagen is the basis of a scar or stretch mark; Fermenkol is aimed at its destruction.

The product also has hyaluronidase activity. This involves the destruction of pathological hyaluronic acid in connective tissue into individual oligosaccharides. Due to this, intercollagen bonds are significantly weakened.

Due to the complex effect on scar tissue, positive results can be achieved. The scar either disappears completely or is significantly reduced in size. The firmness and elasticity of the epidermis increases, and the skin tone is normalized and evened out. As a result of using Fermenkol gel, itching and irritation at the site of scarring disappear.

Fermenkol also affects the skin from the hydration side, namely moisturizing and nutrition. During the use of the drug, dehydrated scar tissue becomes moisturized, and its parameters approach the state of an absolutely healthy epidermis.

Long-term use allows you to achieve deep and complete hydrolysis and destruction of peptide bonds. Deep hydrolysis of hyaluronic acid in the intercellular matrix allows you to achieve quick and lasting results.

As a result of the course of treatment, the following results can be achieved:

• Reduction of stretch marks or scars in size. Minor defects in most cases disappear completely.
• Normalization of the color of the epidermis at the site of scarring. Due to this, the skin color becomes uniform and defects become less noticeable.
• Elimination of itching, irritation and other uncomfortable sensations.
• Increasing the elasticity of the epidermis at the site of a scar or stretch mark.
• The feeling of skin tightness disappears.

Visually, the skin is smoothed, and it also becomes more homogeneous to the touch. The result is achieved by leveling the microrelief of the skin. The gel is most effective against scars; use to eliminate stretch marks gives the least pronounced results.

In some cases, dermatologists recommend this remedy for the treatment of minor burns. In this case, it is not recommended to prescribe the drug yourself, since improper use of the drug can significantly worsen the condition of the epidermis.

How Fermenkol works -

The active components of Fermenkol have high activity in reducing the rate of collagen production in the skin. As you know, scar tissue forms due to increased levels of collagen production. Keloid and hypertrophic scars are formed as a result of an unexplained failure in collagen production - when collagen is produced in excessive, excessive quantities.

Collagenase, which is part of Fermenkol products, selectively acts only on the molecules of pathological collagen contained in the scar tissue of atrophic and keloid scars, destroying them, resulting in a reduction in the scar. According to the manufacturer: Fermenkol has virtually no effect on normal collagen of healthy skin tissue.

Thus, with the help of a complex of enzymes, collagen and elastin fibers are hydrolyzed, which break down into individual amino acids. Enzymes also hydrolyze polysaccharides in scar tissue, such as hyaluronic acid.

Important : Fermenkol only acts on scars that are no more than 1-2 years old, when scar tissue formation is still active.

Technologies that ensure the effectiveness of Fermenkol –

1. Firstly, the manufacturer uses collagenolytic proteases with a molecular weight of only 23,000 to 36,000 Daltons, which ensures good penetration of enzymes deep into scar tissue.
2. Secondly, Fermenkol contains components that increase the permeability of the stratum corneum of the skin by increasing its hydration (moistening), and also increase the permeability of the dermis due to the swelling and loosening of interstitial collagen and elastin.
3. It is also known that scar tissue has very little hydration (moistening) with water when compared to normal skin tissue. A normal level of hydration provides healthy skin with turgor, elasticity, a youthful and healthy appearance. Fermenkol provides not only the hydrolysis of pathological collagen, but also deep hydration of scar tissue, which together ensures a reduction in scars, as well as an improvement in their appearance.

Indications for use

Fermenkol gel is in most cases prescribed to eliminate scars on the skin. The instructions for use indicate other cases when it is advisable to use this particular drug.

The drug may be prescribed to treat burns caused by high temperatures, chemical liquids or harmful radiation. At the moment of regeneration after a burn, the process of accumulation of pathological collagen occurs, its fibrils chaotically intertwine with each other. As a result, a dense texture is formed on the skin.

Fermenkol eliminates excess collagen that accumulates after any burns. For severe burns, it is recommended to use the product in powder form, as it is able to penetrate into the deepest layers of the dermis.

Fermenkol gel is most often used to eliminate scars and post-acne. In this case, it is aimed not only at destroying scar tissue, but also at combating pigmentation. A long course of the drug allows you to completely clear your face of scars. It is recommended to begin treatment as soon as scarring appears on the skin.

Stagnant post-acne responds much worse to all kinds of therapy. Scar tissue becomes almost invisible on the face, as it blends in tone with healthy skin. Pathological collagen is destroyed, which leads to softening of scar tissue.

Phonophoresis using a special Fermenkol kit allows you to achieve results several times faster , but before using the kit at home, you must first consult with a dermatologist.

The product can be used not only after acne spots, but also for scars caused by surgery. In this case, it is very important to start treatment immediately, since it is almost impossible to completely remove a stagnant scar.

But even an old scar can be made less noticeable if the drug is used correctly. For scars after surgery, it is recommended to combine the use of the gel with phonophoresis powder.

Fermenkol is often used to eliminate stretch marks. Relatively recently, a new form of the product was released, called Fermenkol Elactin, designed specifically to combat stretch marks. Some experts compare the product with laser techniques, noting its high efficiency.

The drug acts in several directions:

• Increases skin elasticity at the site of stretch marks.
• Renews the affected area of ​​the epidermis.
• Restores the structure of the skin, making it uniform.
• Stretch marks are considered atrophic scars, and Fermenkol acts specifically on scar tissue.

Due to this, the skin becomes homogeneous, and defects in the form of stretch marks are not so noticeable. In advanced cases, it is recommended to combine the application of the gel and phonophoresis with a special set.

Fermenkol

Name: Fermenkol Pharmacological action: Fermenkol exhibits general proteolytic and collagenolytic activity. Under the influence of active enzymes, collagen breaks down into amino acid residues. These residues are then eliminated from the body. Thorough hydrolysis of peptide bonds entails thinning of the epidermis and scar tissue. Fermenkol has an antipruritic effect and relieves the inflammatory component. The product also eliminates excessive pigmentation of the scar zone and normalizes the hydration of the dermis, due to which the scar tissue acquires elastic properties.

Indications for use: Used for the purpose of remodeling keloid scars and hypertrophied areas of the skin, imperfections resulting from surgical sutures, burns and injuries. It has proven its effectiveness in the treatment of defects formed as a result of acne and its correction.

Method of use: Penetration of active substances into the skin is achieved by application or through electro-, phonophoresis. For home use, Fermenkol gel is convenient, which is applied to a previously cleansed area of ​​skin. Give a light massage. Such manipulations are carried out 2-3 times a day for thirty days of the course. A second course of therapy with Fermenkol is possible after 10–16 days. Applications of the drug can be made using a solution prepared from 40–50 milliliters of saline with powder from the electrophoresis kit. A clean gauze pad with this solution is applied to the scar for half an hour. This procedure is repeated twice a day for one month.

The maximum effectiveness of Fermenkol can be achieved in combination with physiotherapy. With phonophoresis, ultrasonic waves cause active enzymes to penetrate into the deep layers of the dermis. After cleaning the scar area, a flow of energy is activated; its power during manipulations on the torso and limbs should not exceed 300 mW/cm², in the face area - no more than 200 mW/cm². For phonophoresis, a gel form of the drug is also used. During electrophoresis, Fermenkol powder is diluted in a one percent solution of potassium chloride to a concentration of 1 mg/ml. Then add a weak solution of hydrochloric acid. Moisten the napkin with the resulting solution and place it on the scar.

The introduction begins with a positively charged electrode (anode). Localization of the scar on the torso or limbs requires a current density of 0.1 mA/cm², in the case of localization on the face - no more than 0.05 mA/cm², and in children under five years of age - no higher than 0.01 mA/cm². Exposure time is 20–25 minutes. After the procedure is completed, the patient should be observed for another half hour. 10-15 daily procedures constitute one course of therapy. A repeat course is possible after completing 7–10 days from the previous one.

Side effects: Rarely, at the site of Fermenkol application, a feeling of discomfort, slight tingling, burning, and sometimes redness of the scars of the changed area are possible.

Contraindications: The drug is contraindicated if there are: - purulent-inflammatory processes in the acute stage; — diseases of the hematopoietic system; — oncological diseases of a malignant nature; — acute dermatitis and violation of skin integrity; — decompensated hypertension; - if the scar is located on the face - paralysis of the facial nerve; - persistent neurological disorders; - severe endocrine pathology; — the drug is prohibited in children under three years of age; - not used for atrophic scars.

To avoid undesirable consequences, do not use in persons with excessive sensitivity to the components of Fermenkol.

Pregnancy: Fermenkol is not used in the final two trimesters of pregnancy.

Interaction with other medications: No episodes of interaction of the drug with other medications were detected. Fermencol is not recommended to be applied on top of other drugs, as this will distort or reduce its therapeutic effect.

Overdose: There are no known cases of overdose with Fermenkol.

Release form: It is produced by the pharmaceutical industry in the form of a gel and a kit for electrophoresis. The transparent, odorless gel is enclosed in an aluminum tube with a substance mass of 20 grams. The electrophoresis kit consists of a pair of polymer bottles. One of the bottles contains a hygroscopic light yellow powder weighing 4 grams. Another bottle contains 40 ml of clear activator liquid - solactin.

Storage conditions: The electrophoresis kit and Fermenkol gel are stored in a place inaccessible to sunlight. It is forbidden to expose the drug to heating above 40 degrees Celsius and to freeze it. Avoid exposure to moisture. Under the above conditions, the shelf life is 3 years from the date of release. Store the prepared solution at a temperature of 2–6 degrees Celsius above zero.

Synonyms: Lidaza, Contractubex.

Composition: Fermenkol is an enzymatic composition of enzymes that destroy collagen, obtained from the digestive tube of representatives of marine fauna. Its formula does not contain additional impurities in the form of lipoproteins, polysaccharides and pigments.

Nosological classification (ICD-10):

Scar conditions and skin fibrosis (L90.5)

ATX: D11AX

Additionally: Active enzymes when exposed to the superficial layers of the dermis can cause hyperemia. This symptom goes away on its own after completing the course of therapy. Particular attention is paid to use in children, since the drug affects the growth zones. Both dosage forms of Fermenkol are recommended for use after healing of fresh scars, no earlier than three weeks after skin damage.

Attention! The description of the drug " Fermenkol " on this page is a simplified and expanded version of the official instructions for use. Before purchasing or using the drug, you should consult your doctor and read the instructions approved by the manufacturer. Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.

Instructions for use

Fermencol gel (instructions for use describe a detailed treatment regimen for each case) cannot be used for self-prescription. Before starting therapy, it is recommended to consult a dermatologist. The specialist will be able to accurately determine the duration of the course, as well as prescribe the required dosage. If necessary, additional medications may be prescribed.

Fermenkol can be used in 2 ways - using application, as well as during phonophoresis.

The application technique is recommended for fresh scars or stretch marks. A small amount of pathological collagen has accumulated in them, so the use of an external gel will be sufficient.

Application involves the following sequence:

1. Cleanse skin with a mild cleanser without harsh fragrances.
2. Dry the skin.
3. Apply the gel in a circular motion to the area of ​​the scar, scar, stretch marks or burn. At the same time lightly massaging. Allow the product to be completely absorbed.
4. Repeat the procedure 2-3 times a day.

The course of treatment is individual for each patient. On average, its duration is 1 month. If necessary, therapy can be extended for a longer period.

The phonophoresis technique is suitable for severe cases. It involves the use of an external agent in conjunction with a device that produces ultrasonic waves. This device is easy to use and suitable for independent home use.

The technique involves applying Fermenkol gel or powder to the affected area of ​​the skin, and then influencing it using a device. Ultrasonic waves allow the components of the drug to penetrate into the deep layers of the dermis, which makes application more effective.

The duration of one procedure for adults should not exceed 5 minutes. For children, exposure time is 3 minutes. The duration of the course is determined depending on the stage of skin damage.

Fermenkol: reviews from scars, photos

Fermenkol - reviews show that the drug really reduces the severity of hypertrophic scars by about 10-20%.
Moreover, the drug can be used not only to treat existing scars, but also to prevent their occurrence. Thanks to phonophoresis with Fermenkol gel, reviews from scars noted: → blanching of scars, → reduction of scars in size, → reduction in the density of scar tissue, → reduction in skin tightening, → increase in elasticity of scar skin, → reduction or complete cessation of itching.

Reviews included the following disadvantages of the drug Fermencol:

• high cost of the drug,
• quick consumption (apply 3 times a day),
• short period of validity after opening the tube.

Important : reviews also noted that after 2012 (when the manufacturer slightly changed the composition of the drug) its effect significantly worsened. Patients with acne scars who used the drug regularly complained about this especially. Also, when analyzing the manufacturer’s website, we noted that all the rave reviews published there are certainly of an advertising nature, and were clearly left not by patients, but by the manufacturer himself.

It is also worth noting that the drug (and this is normal) cannot act equally on all patients, which is due to the individual characteristics of scar formation in different people. The effectiveness of the drug may be influenced by: features of traumatic tissue damage, features of the scalpel incision, quality of suturing, genetic predisposition to keloid scars, autoimmune and endocrine diseases, time of treatment, etc.

Features of use during pregnancy

Pregnancy is not a direct contraindication to the use of the drug. The product is intended for external use, so it is not dangerous to the health of mother and child.

It is worth considering that during pregnancy, skin reactions can be unpredictable. During this period, under the influence of hormones, she is most prone to various allergic reactions. It is also possible that the effectiveness of therapy will decrease. If any side effects occur, it is recommended to stop treatment immediately.

Side effects

The use of the drug is almost always easily tolerated by patients; it extremely rarely causes side effects.

Possible adverse reactions include the following:

• allergic reactions;
• the appearance of itching, irritation and urticaria in the areas where the product is applied;
• local redness and increased skin temperature;
• a tingling feeling that disappears fairly quickly.

Any side effects when using Fermenkol are mild. They may disappear on their own during the treatment process as the skin adapts to the drug. If unwanted reactions do not disappear, it is recommended to choose another drug.

Reviews about Fermenkol

On the Internet you can find numerous reviews about Fermenkol. In most cases, the cosmetic product is evaluated positively, noting its effectiveness, ease of use, natural composition, absence of dyes and fragrances, good tolerance and the rare occurrence of allergic reactions.

The disadvantages of the product include its high cost and short shelf life of opened packaging. Some patients note its low effectiveness and rapid consumption. Also in reviews you can find information that the drug is not sold in all pharmacies.

Interactions

Fermenkol gel (instructions for use are presented for informational purposes only and do not replace the official instructions for the product) does not imply interaction with other medications.

In order to maintain the effectiveness of the product, it is not recommended to apply it to the skin immediately after other local medications. If you have a tendency to allergic reactions, it is recommended to first consult with a specialist if complex treatment is planned.

special instructions

Applying the drug to areas with violations of the integrity of the skin does not imply danger. If the gel or powder gets into your eyes, you must immediately rinse them with warm, clean water.

Fermenkol is allowed to be used locally after malignant neoplasms, but only with caution and after consulting an oncologist. During the treatment process, it is necessary to be regularly monitored by a specialist. It is not recommended to apply cosmetics immediately after using the drug; it is advisable to wait a while.

Terms of sale and storage

The drug must be stored in a dry and dark place, out of reach of children. The temperature should be from 0 to +25 degrees. An open tube of gel must not be stored for more than 1 month. The finished solution can be stored for a week if the temperature is maintained. Recommended temperature is from +1 to +6 degrees. The sealed period is 3 years.

The drug is freely available and does not require a prescription to purchase it.

Directions for use and dosage:

• Step 1. Remodulation of the skin structure in the area of ​​stretch marks.

Before going to bed, apply Fermenkol S gel to clean, dry skin in the area of ​​stretch marks and, using a special dispenser, rub in until completely absorbed. Use daily for 1.5-2 months.

• Step 2. Restoring the skin structure in the area of ​​stretch marks.

In the morning, apply Elactin gel to clean, dry skin in the area of ​​stretch marks and, using a special dispenser, rub in until completely absorbed. Use daily for 1.5-2 months.

Cheap and expensive analogues

The drug has many analogues from different price categories.

Inexpensive substitutes include the following:

1. Dermofibrase.
2. Lidaza.
3. Vinitan Forte.
4. Kelotan.
5. Rescuer.
6. Contratubeks.

More expensive products include the following:

1. Kelo-Kot.
2. Strataderm cream.
3. Stratamed.
4. Collost.
5. Dermatix.

The drugs have a similar principle of action, but differ in their composition. The selection of a substitute is advisable in case of individual intolerance to the components and hypersensitivity to them.

If you have a tendency to allergic reactions, it is necessary to first check for allergies when using each product and begin therapy gradually.

Price of the drug in Moscow, St. Petersburg and regions

The cost of the product differs depending on the region of sale. Approximate prices will be presented in the table below.

The drug can also be purchased from online pharmacies. The average cost in this case is 850-950 rubles. The price is for Fermencol gel 10 mg. A volume of 30 mg costs on average 1500-1600 rubles.

Reviews from dermatologists about the effectiveness of the product

Experts note that Fermencol is several times more effective than many well-known drugs. Compared to products such as Contratubeks, Collagenase or Kelotan, Fermenkol provides the fastest results.

In severe cases, dermatologists and cosmetologists recommend using not only a gel for topical application, but also combining it with phonophoresis. This approach allows you to destroy the structure of a scar, scar, burn or stretch mark in the deep layers of the epidermis. That is why many experts compare the Fermenkol treatment course with laser correction techniques.

Unlike laser, Fermenkol has practically no contraindications, it is easily tolerated by patients, rarely provokes side effects and does not require a rehabilitation period.

To achieve the desired result, dermatologists recommend taking a course of therapy, which on average includes 20 phonophoresis procedures and regular application of gel to the affected areas for a month.

Not only doctors and cosmetologists note the high results from using the product. Most patients were also satisfied; reviews of this drug were mostly positive. People note a mild effect, quick results, as well as a general improvement in the condition of the skin.

Many experts note the high effectiveness of the use of Fermencol gel. To achieve maximum results, they recommend strictly following the instructions for use.

Author: Kolenova Victoria

Pharmacological properties

Fermencol has a collagenolytic effect. It ensures deep hydrolysis of collagen, breaking peptide bonds between amino acids. The drug exhibits selective activity against pathological collagen molecules with vortex and nodular packing. It exhibits less activity against fibrils of native collagen present in healthy tissue. The destruction of excess collagen leads to scar reduction.

Fermencol also has a general proteolytic effect and is capable of hydrolyzing polysaccharides. Thanks to this, a complex effect is achieved on the components of scar tissue.

When Fermenkol is used to eliminate acne and its consequences, the scar capsule around the inflamed glands is destroyed, as a result of which they are cleansed, the volume of scar tissue is reduced and the skin is smoothed.

Thanks to the use of a cosmetic product, the following effects are observed:

• the volume of the scar decreases;
• the color of the skin in the scar area is normalized;
• itching and discomfort are reduced;
• the feeling of tightness is removed;
• The elasticity of the skin in the scar area increases.