A severe dry cough with poorly separated sputum requires the use of medications to change the properties of the secretion produced by the bronchi. Treatment leads to a decrease in the viscosity of mucus, its accelerated evacuation from the respiratory tract, the free passage of air into the lungs and the regeneration of damaged mucous membranes. One of the representatives of such drugs is powdered “ACC”.
General information
The medicine is an expectorant-type mucolytic, which allows you to accelerate the accumulation of sputum in the respiratory section. The product consists of small granular particles, each sachet contains 200 mg of active ingredients. The composition of the medication is represented by the following components:
- acetylcysteine;
- ascorbic acid;
- sucrose, saccharin;
- honey and citrus flavoring.
Granules are white, less often yellowish, with a pronounced aroma of honey and citrus.
An increase in the fluidity of thick mucous secretion, which arises under the influence of pathogenic microflora, occurs due to the active component acetylcysteine. Its effectiveness has been proven in clinical studies; good results are obtained even in the presence of purulent clots in the sputum.
Indications for use
The use of ACC 200 is indicated in the following cases:
- for diseases of the respiratory system, if the formation of viscous sputum occurs, which is difficult to separate ( laryngotracheitis , acute / chronic / obstructive bronchitis, bronchiectasis, cystic fibrosis, pneumonia, bronchial asthma , bronchiolitis );
- otitis media;
- sinusitis acute and chronic.
Recommendations for admission
The manufacturer's instructions indicate the diseases for which the drug can be used. Among the pathological processes that cause acute nonproductive cough are:
- bronchial asthma;
- lung abscesses;
- bronchiectasis;
- cystic fibrosis;
- inflammation of the bronchioles - bronchiolitis;
- chronic obstructive pulmonary disease;
- pneumonia;
- acute, chronic form of bronchitis;
- tracheitis and laryngotracheitis.
The annotation for the drug indicates the main adverse reactions and contraindications for use. The product should not be used:
- in acute form or exacerbation of a chronic ulcer;
- bleeding in the respiratory tract, accompanied by the release of blood particles along with secretions;
- glucose-galactose malabsorption syndrome;
- during pregnancy and breastfeeding;
- in childhood - up to 6 years.
The drug is contraindicated in patients with a tendency to spontaneous allergic reactions or congenital intolerance to one of the components that make up the powder. Particular caution should be exercised before use by patients with a history of certain diseases:
- with arterial hypertension - constantly elevated blood pressure;
- ulcers – gastrointestinal, esophagus;
- pathologies of the adrenal glands;
- liver, kidney failure;
- histamine intolerance.
Long-term use of medications can become a source of allergies, respiratory problems, and dyspeptic disorders. These deviations occur as a result of an overdose. The manufacturer advises using the medication strictly according to the instructions, without independently increasing the dose or duration of administration.
Buy ACC 200 powder for preparing a solution for oral administration Orange 3g No. 20 in pharmacies
ACC Buy ACC in pharmacies DOSAGE FORMS granules for the preparation of solution for oral administration orange 200 mg
MANUFACTURERS Salutas Pharma GmbH (Germany)
GROUP Mucolytic agents
COMPOSITION The active substance is acetylcysteine.
INTERNATIONAL NON-PROPENTED NAME Acetylcysteine
SYNONYMS Acetylcysteine, Acetylcysteine Sediko effervescent instant, Acetylcysteine Stada International, Acetylcysteine-Hemofarm, ACC 100, ACC 200, ACC injection, ACC Long, Vicks Active ExpectoMed, Muco Sanigen, Mukobene, Mukonex, Tussicom, Fluimucil
PHARMACOLOGICAL ACTION Mucolytic agent. Pharmacodynamics. The presence of sulfhydryl groups in the structure of acetylcysteine promotes the rupture of disulfide bonds of acidic mucopolysaccharides of sputum, which leads to a decrease in the viscosity of mucus. The drug remains active in the presence of purulent sputum. With the prophylactic use of acetylcysteine, there is a decrease in the frequency and severity of exacerbations in patients with chronic bronchitis and cystic fibrosis.
INDICATIONS FOR USE Diseases of the respiratory system, accompanied by the formation of viscous, difficult to separate sputum: acute and chronic bronchitis, obstructive bronchitis, laryngotracheitis, pneumonia, bronchiectasis, bronchial asthma, bronchiolitis, cystic fibrosis. Acute and chronic sinusitis, inflammation of the middle ear (otitis media).
CONTRAINDICATIONS Hypersensitivity to acetylcysteine or other components of the drug, pregnancy, breastfeeding, children under 2 years of age.
SIDE EFFECTS In rare cases, headaches, inflammation of the oral mucosa (stomatitis) and tinnitus are observed. Extremely rare - diarrhea, vomiting, heartburn and nausea, drop in blood pressure, increase in heart rate (tachycardia). In isolated cases, allergic reactions such as bronchospasm (mainly in patients with bronchial hyperreactivity), skin rash, itching and urticaria are observed. In addition, there are isolated reports of bleeding due to hypersensitivity reactions. If side effects develop, you should stop taking the drug and consult a doctor.
INTERACTION With the simultaneous use of acetylcysteine and antitussives, mucus stagnation may occur due to suppression of the cough reflex. Therefore, such combinations should be selected with caution. The simultaneous use of acetylcysteine and nitroglycerin can lead to an increase in the vasodilatory effect of the latter. Pharmaceutically incompatible with antibiotics (penicillins, cephalosporins, erythromycin, tetracycline and amphotericin B) and proteolytic enzymes. Upon contact with metals and rubber, sulfides with a characteristic odor are formed. Reduces the absorption of penicillins, cephalosporins, tetracycline (they should be taken no earlier than 2 hours after ingestion of acetylcysteine).
METHOD OF APPLICATION AND DOSAGE In the absence of other prescriptions, it is recommended to adhere to the following dosages: Mucolytic therapy. Adults and adolescents over 14 years of age are recommended to take 1 sachet 2 - 3 times a day (400 - 600 mg per day). Children aged 6 to 14 years are recommended to take ACC® 200 mg 3 times a day, 1 sachet or 2 times a day, 1 sachet (300 - 400 mg per day). Children aged 2 to 5 years are recommended to take 2-3 times a day, 1/2 sachet (200-300 mg per day). Cystic fibrosis. Children over 6 years of age are recommended to take 1 sachet (600 mg per day) 3 times a day. Children aged 2 to 5 years are recommended to take 1/2 sachet (400 mg per day) 4 times a day. For patients with cystic fibrosis and a body weight of more than 30 kg, if necessary, the dose can be increased to 800 mg of acetylcysteine per day. The granules should be dissolved in water, juice or iced tea and taken after meals.
OVERDOSE In case of erroneous or intentional overdose, phenomena such as diarrhea, vomiting, stomach pain, heartburn and nausea are observed. To date, no severe or life-threatening side effects have been observed.
SPECIAL INSTRUCTIONS With caution - peptic ulcer of the stomach and duodenum in the acute stage; hemoptysis, pulmonary hemorrhage, esophageal varices, bronchial asthma, adrenal diseases, liver and/or kidney failure. Pregnancy and breastfeeding For safety reasons, due to insufficient data, the use of the drug during pregnancy and breastfeeding is only possible if the expected benefit to the mother outweighs the potential risk to the fetus or infant. For patients with bronchial asthma and obstructive bronchitis, acetylcysteine should be prescribed with caution under systematic monitoring of bronchial patency. When treating patients with diabetes, it is necessary to take into account that the drug contains sucrose. When working with the drug, you must use glass containers and avoid contact with metals, rubber, oxygen, and easily oxidized substances.
STORAGE CONDITIONS Store in a dry place, protected from light, at a temperature not exceeding 25 C.
Terms of use
The rules for diluting the medicine are specified in the annotation. To create a liquid solution, the simplest algorithm is performed:
- The package is carefully opened along the cut line;
- pour into a cup;
- pour 3200 ml of hot water;
- stir.
The manufacturer points out that you cannot pour boiling water over the medicine - just use hot water.
To get the maximum effect from the medicine, you must consider:
- that the prepared solution is consumed immediately after eating and cannot be stored;
- a hot drink is absorbed faster into the gastrointestinal tract and accelerates the expected mucolytic effect;
- if the patient has a low-grade fever or fever, then cool the mixture before taking it;
- You should not use a drug prepared more than 3 hours ago - it is no longer suitable and will not be able to perform its intended functions.
You can also drink other warm liquids along with the medication. They will replenish losses, accelerate the liquefaction of sputum and speed up recovery.
The list of special dosage regimens includes:
- The need for long-term therapy is daily intake of 400 to 600 mg, divided into several procedures. The duration of the manipulations should not exceed 3-6 months, the final dates are set by the local therapist.
- Treatment of cystic fibrosis - 200 mg three times a day.
If excessive secretion and cough continue after two weeks of therapy, then a repeat diagnostic examination and revision of the initial diagnosis is necessary.
pharmachologic effect
The product has a mucolytic effect. Due to the fact that the structure of the molecule contains acetylcysteine sulfhydryl groups, the disulfide bonds of acidic mucopolysaccharides of sputum are broken. As a result of this process, the viscosity of the mucus decreases. ACC 200 also demonstrates activity in patients with purulent sputum.
If acetylcysteine is used for prophylactic purposes, in patients who suffer from cystic fibrosis and chronic bronchitis , the severity and frequency of exacerbations decreases.
special instructions
If ACC 200 is prescribed to patients with bronchial asthma and obstructive bronchitis, it is necessary to do this carefully and constantly monitor bronchial patency.
If any side effects develop, you should stop treatment and consult a doctor.
If necessary, dissolve the drug using glass containers.
Doctors do not recommend taking the drug before bed. It is advisable to do this before 18:00.
Patients with diabetes should note that ACC 200 contains sucrose.
The drug does not affect the ability to concentrate or drive vehicles.
Analogs
Level 4 ATX code matches:
Mukolik
Abrol
Ambrosan
Bronchorus
ACC 100
ACC Long
ACC
Mukolwan
Lazolvan
Bromhexine 8
Bromhexine 8 Berlin-Chemie
Bromhexine
Bronchobos
Carbocisteine
Erdomed
Pulmozyme
Pectolvan C
Halixol
Ambrobene
Acetylcysteine
Drugs that are analogues of ACC 200 are drugs ACC Long , Fluimucil , Acetylcysteine , N-acetylcysteine , Mucomist , Acestin , Mukonex , etc. Which of these drugs is the most optimal is determined by the doctor individually.
Interaction
It should be borne in mind that when taking ACC 200 and other cough suppressants simultaneously, dangerous mucus stagnation may develop due to the fact that the cough reflex is suppressed. Therefore, such drugs must be combined carefully.
Acetylcysteine may enhance the vasodilatory effect of Nitroglycerin if these drugs are taken simultaneously.
There is a synergism between acetylcysteine and bronchodilators.
Acetylcysteine is not compatible pharmaceutically with antibiotics (penicillins, cephalosporins, Amphotericin B , Erythromycin , Tetracycline ) and proteolytic enzymes .
When taken simultaneously, acetylcysteine reduces the absorption of tetracycline, cephalosporins, and penicillins. Therefore, you need to take such drugs at intervals of at least two hours.
If acetylcysteine comes into contact with rubber or metals, sulfides are formed, which have a characteristic odor.
Side effects
The following side effects may occur while taking the drug:
- nervous system: tinnitus, headache ;
- cardiovascular system: decreased blood pressure , tachycardia ;
- digestion: diarrhea , nausea, vomiting, stomatitis ;
- allergic reactions: isolated manifestations - bronchospasm , urticaria , itching , skin rash;
- other reactions: isolated manifestations - bleeding.
Price ACC 200, where to buy
The price of ACC 200 is on average 300 rubles for 20 pieces.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
ZdravCity
- ACC 200 tab.
thorn. 0.2g 20pcs UNDEFINED RUR 132 order
Pharmacy Dialogue
- ACC 200 (pack of granules 200 mg No. 20 (orange)) Salutas Pharma GmbH
117 RUR order
- ACC 200 (spike tab. 200 mg No. 20) Salutas Pharma GmbH
123 RUR order
- ACC 200 (spike tab. 200 mg No. 20) Hermes
116 RUR order
- ACC 200 (pack of granules 200 mg No. 20 (orange)) Lindofarm
117 RUR order
show more
Pharmacy24
- ACC 200 No. 20 tablets Salutas Pharma GmbH., Nimechchina/Hermes Pharma Ges.m.b.H., Austria
128 UAH order - ACC 200 mg No. 20 powder for oral use Salutas Pharma GmbH, Nimechchina / Lindopharm GmbH, / Zambon Switzerland Ltd, Switzerland
152 UAH order
