Bellasthesin: how to use, contraindications, cost


Pharmacodynamics and pharmacokinetics

The effect of the drug is due to two active components included in its composition.

Belladonna extract contains atropine group alkaloids – hyoscyamide, apoatropine and scopolamine. These substances tend to reduce the tone of smooth muscles and the gastrointestinal tract (spasmolytic effect) and reduce the secretion of the pancreas, salivary, gastric, bronchial and sweat glands (antisecretory effect).

Benzocaine is a strong analgesic - anesthesin . It has an analgesic effect on the mucous membrane of the stomach and esophagus.

Characteristics of the drug

Bellasthesin is available only in tablet form. One piece contains two main active ingredients:

  • 300 mg benzocaine;
  • 15 mg belladonna extract (belladonna leaf extract).

Potato starch, talc, calcium stearate, colloidal silicon dioxide, sodium carboxymethyl starch are present as excipients.

The tablets have a flat oval shape and a score. The color is uneven, predominantly brown, with patches of light and dark shades.

Packaged in plates with cells of 10 pieces. Depending on the manufacturer, it may be sold in a box with an annotation or without a box.

Contraindications

Taking the drug is contraindicated:

  • with hypersensitivity ( allergy ) to belladonna , benzocaine , other amide anesthetics and drug components;
  • for glaucoma ;
  • myasthenia gravis;
  • thyrotoxicosis;
  • for arrhythmia , heart failure , tachycardia , ischemia , mitral stenosis , high blood pressure;
  • with hyperthermic syndrome ;
  • acute bleeding;
  • with a tendency to urinary retention.

Contraindications to the use of the drug Bellastesin

  • hypersensitivity to benzocaine, belladonna extract and other components of the drug;
  • stenosing gastrointestinal diseases;
  • intestinal atony, atonic constipation;
  • acute ulcerative colitis;
  • mechanical intestinal obstruction;
  • pronounced atherosclerosis;
  • tachyarrhythmia; – acute bleeding;
  • myasthenia gravis;
  • glaucoma or suspected glaucoma;
  • prostate adenoma;
  • children up to 14 years of age.

Side effects

Possible:

  • dry mouth, impaired sense of taste, atony , decreased tone of the gallbladder, feeling of thirst, constipation ;
  • facial flushing, palpitations, myocardial ischemia , arrhythmia , hot flashes ;
  • fear of bright light, increased intraocular pressure , dilated pupils, problems with accommodation ;
  • urticaria , skin rashes, hyperemia ;
  • dysarthria , dry skin;
  • urinary retention;
  • headaches and loss of consciousness;
  • formation of viscous sputum, which is difficult to expectorate;
  • anaphylactic shock.

If the above reactions occur, you should stop taking the drug and consult a specialist.

Side effects of the drug Bellastesin

Bellasthesin is well tolerated, but the following side effects are sometimes possible. From the central nervous system : headache, dizziness, nervousness, drowsiness, agitation (especially in elderly patients), weakness, sleep disorders, ataxia (disorders of motor coordination), speech impairment. From the gastrointestinal tract : dry mouth, loss of taste, anorexia, constipation; From the organ of vision : mydriasis. From the cardiovascular system : tachycardia. Other: allergic reactions may occur.

Overdose

The most common symptoms of overdose are: nausea , tachycardia , irritability, overexcitation, tremor , insomnia , hallucinations , depression of the central nervous system , nausea, drowsiness .

In case of overdose, the stomach should be lavaged, symptomatic therapy should be performed, and cholinomimetics and anticholinesterase agents .

Precautions for use

Bellasthesin is not prescribed to children, persons with hypersensitivity to substances contained in the drug, as well as for angle-closure glaucoma and prostate adenoma.

For the following pathologies, the medication can be used with caution:

  • multiple damage to nerve endings;
  • hyperfunction of the thyroid gland;
  • IHD;
  • increased blood pressure;
  • kidney pathologies;
  • chronic heart failure syndrome;
  • hiatal hernia;
  • inflammation of the mucous membrane of the esophagus.

Undesirable responses from the body are likely to include:

  • allergic reactions;
  • dizziness;
  • dry mouth;
  • dilated pupils;
  • loss of taste, loss of appetite;
  • increased heart rate;
  • excited state of the nervous system or drowsiness;
  • problems with stool and urination.

If discomfort occurs after taking the tablets, the course of treatment must be interrupted and contact the supervising doctor to change the medication.

Interaction

When taking other medications, you should consult your doctor.

When combined with haloperidol, butyrophenones , and organic nitrates, a strong increase in intraocular pressure occurs.

The anticholinergic effects of the drug are enhanced if it is combined with amantadine , quinidine , arrhythmia drugs, tricyclic antidepressants , glutethimine .

When combined with opioid painkillers , phenothiazines , or central nervous system depressants , dangerous depression of nervous system function may occur .

The drug reduces the effectiveness of corticosteroids , pilocarpine , griseofulvin , digitoxin , metronidazole , metoclopramide , levodopa beta-adrenergic blockers , sulfonamides and hormonal contraceptives.

The combination of Bellasthesin and m-anticholinergics leads to increased effectiveness of the latter.

The therapeutic effect of the drug is reduced if taken with reserpine , guanethidine , vitamin C , atapulgite , and MAO inhibitors .

furosemide with caution .

The drug enhances the antihistamine activity of meclizine and similar drugs.

The absorption of ketoconazole is significantly reduced due to the fact that the pH of gastric juice increases. Between these drugs you should take a break of at least 2 hours.

The medicine should not be combined with potassium chloride , as damage to the gastric mucosa may occur.

The effectiveness of Nizatidine and Indapamide when taken simultaneously with Bellasthesin increases.

Interactions of the drug Bellastesin

Bellasthesin reduces the antibacterial activity of sulfonamides. Amantadine and quinidine enhance the effect of Bellasthesin. When Bellasthesin is used concomitantly with opioid analgesics and CNS depressants, dangerous CNS depression is possible; with haloperidol and organic nitrates - intraocular pressure increases; with GCS for systemic use - the effect of corticosteroids is reduced and intraocular pressure may increase; with M-cholinergic blockers - the anticholinergic effect is enhanced; with furosemide - orthostatic hypotension is possible. Reserpine, MAO inhibitors, guanethidine, antacids, ascorbic acid, attapulgite reduce the effect of Bellasthesin. When Bellasthesin is used simultaneously with antihistamines, the antihistamine effect is enhanced; with β-adrenergic receptor blockers - the effect of the latter is reduced; with hormonal contraceptives - the contraceptive effect is reduced; with non-selective inhibitors of neuronal monoamine reuptake - the sedative effect is enhanced. Bellasthesin reduces the effect of NSAIDs, griseofulvin, digitoxin, doxycycline, ketoconazole, metoclopramide, metronidazole; increases the effect of indapamide, nizatidine. When Bellastesin is used simultaneously with drugs containing potassium, the formation of ulcers in the intestines is possible.

special instructions

In no case is it recommended to exceed the indicated dosage.

You should not drink alcohol while taking the drug .

Be careful:

  • with renal failure and liver diseases;
  • with obstruction of the biliary tract;
  • with cerebral palsy , brain damage, with Down's syndrome ;
  • with chronic lung diseases;
  • with intestinal inflammation, Crohn's disease , with reflux esophagitis ;
  • elderly patients, debilitated patients, with dry mouth.

If it is necessary to take the drug during breastfeeding , it should be discontinued. During pregnancy , a doctor can prescribe medicine if there is an urgent need for it.

The drug affects the reaction rate; it is not recommended to operate machinery or a car while taking the drug.

Due to the insufficient number of clinical trials, the drug is not prescribed to children.

Special instructions for the use of Bellastesin

Use with caution in patients with polyneuropathy, hyperthyroidism, ischemic heart disease, CHF, hypertension (arterial hypertension), kidney disease, diaphragmatic hernia, reflux esophagitis. Long-term use is not recommended for gallstone disease and nephrolithiasis. At high ambient temperatures, the use of Bellasthesin can lead to heat stroke. Use during pregnancy and lactation is possible only if the expected benefit to the mother outweighs the potential risk to the fetus. During treatment with the drug, it is recommended to stop breastfeeding. The ability to influence the reaction rate when driving vehicles or other mechanisms. The drug is not recommended for use by persons whose activities require high concentration and rapid mental and physical reactions. Children. There are no clinical data on the effectiveness and safety of the drug in children, therefore the use of Bellastesin in patients under the age of 14 years is not recommended.

Bellasthesin price, where to buy.

The price of the product is approximately 70 rubles for 10 tablets.

  • Online pharmacies in RussiaRussia
  • Online pharmacies in UkraineUkraine

ZdravCity

  • Bellasthesin tab.
    n10 JSC Tatkhimpharmpreparaty 73 rub. order

Pharmacy Dialogue

  • Bellastezin (tab. No. 10) Vifitech CJSC

    67 RUR order

  • Bellasthesin (tab. No. 10) TCPP

    65 rub. order

show more

Pharmacy24

  • Bellastesin No. 10 tablets TOV "Agrofarm", Ukraine
    22 UAH. order

Reviews

On the Internet, patient opinions about Bellasthesin are mostly positive. It copes well with stomach pain due to gastritis with high acidity. The low price and rapid onset of effect are emphasized as advantages. The downside is that it cannot be used for a long time.

Gastroenterologists often prescribe tablets as part of complex therapy, but warn about short-term use. The disadvantages include the need to study the interaction of the drug with other medications if they are taken by patients.

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