Compound
1 tablet contains:
- vitamin E (alpha-tocopherol acetate);
- vitamin A (synthetic retinol palmitate);
- vitamin B5 (calcium pantothenate);
- vitamin B2 (riboflavin);
- vitamin C (ascorbic acid);
- vitamin D3 (oil form, colecalciferol concentrate);
- vitamin B 1 (thiamine mononitrate);
- vitamin PP (nicotinamide);
- vitamin B12 (cyanocobalamin in mannitol);
- vitamin B6 (pyridoxine hydrochloride).
Additional substances: flavors (peach, tangerine), liquid dextrose (dry matter), lactose monohydrate, defoamer, emulsion wax, povidone, sunset yellow dye, glycerol , sucrose, titanium dioxide, castor oil , polysorbate-80, sorbitol .
Pharmacological properties of the drug Makrovit
Macrovit is a multivitamin preparation that contains 10 essential vitamins involved in the regulation of numerous biochemical processes in the body. B vitamins (B1, B2, B6), pantothenic acid and nicotinamide are involved in the metabolism of proteins, fats and carbohydrates and are necessary for the normal functioning of the nervous system. Vitamin A (retinol) stimulates epithelial repair and regenerative processes, and is involved in the synthesis of visual pigment. Actively absorbed in the intestine, absorption is associated with the presence of lipids and is enhanced by the action of bile. Deposited and metabolized in the liver, excreted in the form of metabolites in bile and urine. Vitamin D3 (colecalciferol) regulates calcium metabolism and ensures proper mineralization of bones and teeth. Absorbed in the stomach and intestines; a small amount of the vitamin manifests itself primarily in the form of a lipoprotein complex (chylomicron fraction). Activated in the liver and adipose tissue. Excreted in bile. Vitamin C (ascorbic acid) accelerates the absorption of iron in the digestive tract and is involved in redox processes. Absorbed by active transport and passive diffusion. Distributed in all tissues of the body, excreted in the urine unchanged and in the form of a metabolite (ascorbic acid-2-sulfate). Vitamin E (α-tocopherol) is a physiological antioxidant that protects cell membranes from free radical damage and promotes their normal functioning. After absorption in the digestive tract, it is quickly distributed in all tissues of the body. It is slowly excreted in bile and in the form of metabolites in urine. Nicotinamide (vitamin PP) is absorbed almost completely by active transport and passive diffusion. Distributed in all tissues of the body, up to 70% is excreted unchanged in the urine. Calcium pantothenate is quickly and almost completely absorbed from the digestive tract. Up to 70% of pantothenic acid is excreted unchanged in the urine. Riboflavin (vitamin B2) is rapidly absorbed from the upper gastrointestinal tract through a specific transport mechanism that involves phosphorylation to flavin mononucleotide or flavin phosphate. It is not deposited in the body in significant quantities and is excreted unchanged and as a metabolite in the urine. Thiamine (vitamin B1) is absorbed in the digestive tract by passive diffusion. It is not deposited in the body in significant quantities. Converted to the active pyrophosphate form by enzymes in brain and liver tissue. Excreted in urine. Pyridoxine (vitamin B6) is absorbed in the small intestine by passive diffusion. Different forms of the vitamin (pyridoxine, pyridoxal and pyridoxamine) easily transform into one another in the body. It is excreted mainly in the urine. Cyanocobalamin (vitamin B12), in the presence of gastric juice and pancreatic proteases, binds to internal factor - a glycoprotein secreted by stomach cells, as well as blood plasma proteins and is excreted in bile.
pharmachologic effect
Multivitamins. The medicine contains a set of vitamins necessary for the full course of numerous biochemical reactions in the human body.
B vitamins (pyridoxine (B6), thiamine (B1), nicotinamide (P), pantothenic acid (B5), riboflavin (B2)) take an active part in the synthesis of neurotransmitters , in erythrocyte metabolism, carbohydrate, fat and protein metabolism .
Colecalciferol (vitamin D) is necessary for the complete absorption of calcium.
Retinol (vitamin A) is involved in the biological synthesis of a specific light-sensitive pigment in the retina.
Ascorbic acid (vitamin C) is involved in oxidation-reduction processes and is necessary for the absorption of iron.
Tocopherol (vitamin E) is a natural, physiological antioxidant that helps maintain the functional activity of cell membranes, acting as their protector.
Macrovit tablet p/o in blister. in pack №10x3
Name
Makrovit.
Description
Round, biconvex, orange-colored, film-coated tablets.
Main active ingredient
Multivitamin.
Release form
Chewable lozenges.
pharmachologic effect
Macrovit® contains 10 of the most important vitamins that take part in the regulation of numerous biochemical processes in the body. B vitamins (B1, B2, B6, pantothenic acid and nicotinamide) are involved in the metabolism of carbohydrates, fats and proteins, as well as in the functioning of the nervous system. Vitamin A is necessary for the development of epithelial cells and the biosynthesis of light-sensitive pigment in the retina. Vitamin D plays an important role in maintaining calcium balance and promoting proper mineralization of bones and teeth. Vitamin C increases the absorption of iron and is involved in many redox processes in the body. Vitamin E is a natural antioxidant that protects cell membranes from damage and maintains their functionality.
Indications for use
Macrovit® is used to replenish vitamin deficiencies when the need for them cannot be satisfied by an appropriate diet. Taking the drug does not replace a balanced and varied diet.
Directions for use and doses
Children from 6 to 10 years: 1 film-coated tablet, 1-2 times a day. Children over 10 years of age and adults: 1 film-coated tablet, 2-3 times a day. The duration of use is determined by the doctor.
Use during pregnancy and lactation
If you are pregnant or breastfeeding, think you may be pregnant, or are planning to become pregnant, consult your doctor or pharmacist before taking Macrovit®. Pregnant and lactating women can take vitamins only on the recommendation of a doctor.
Precautionary measures
If you are taking Makrovit®, consult your doctor or pharmacist before you start taking other vitamins, vitamin-mineral and/or mineral complexes. Use with other vitamin preparations is not recommended to avoid overdose and side effects. If an allergic reaction to the components of the drug occurs, the drug should be stopped. Use caution when taking the drug if you have liver disease, acute inflammatory processes in the kidneys, cardiac decompensation, cholelithiasis, chronic inflammation of the pancreas, a history of gastric or duodenal ulcers, a tendency to allergic diseases and thrombosis, idiosyncrasy or tumors. Consult your doctor if you have hemochromatosis, thalassemia, polycythemia, leukemia and sideroblastic anemia. Macrovit® may affect the results of some laboratory tests. Tell your doctor that you are taking Macrovit® before getting tested. Yellow coloration of urine may occur due to the presence of vitamin B2 in the drug. This is completely harmless and will go away spontaneously when you stop taking Macrovit®. If you have diabetes, you should remember that one film-coated tablet contains 0.61 g of sucrose and 0.15 g of glucose, the daily dose contains up to 1.8 g of sucrose and up to 0.45 g of glucose. Macrovit® is not recommended for use in children under 6 years of age. Children aged 6-14 years should take Macrovit® only on the advice of a doctor or pharmacist. Special warnings regarding excipients Macrovit® contains lactose, liquid glucose, sucrose and sorbitol. If you have an intolerance to certain sugars, consult your doctor before taking this medicine. Makrovit® contains the dye Sunset Yellow FCF (E110), which can cause allergic reactions.
Interaction with other drugs
Tell your doctor or pharmacist if you are taking, have recently taken, or may take any other medicines. It is not recommended to take Macrovit® together with oral retinoids (their combination can be toxic), nitrites and cholestyramine. Before taking Macrovit®, consult your doctor if you are taking thiazide diuretics, levodopa, glucocorticosteroids, beta blockers, cardiac glycosides. You may need to adjust the dose of your medications. Co-administration of the drug Makrovit® with drugs such as cimetidine, PAS, potassium preparations, salicylates, corticosteroids, tricyclic antidepressants, imipramine, amitriptyline, laxatives, phenytoin, barbiturates may affect the absorption, metabolism and activity of some vitamins included in Makrovit ®. The absorption of vitamins can be affected by the simultaneous consumption of fruit and vegetable juices and alkaline drinks. Macrovit® interacts with some drugs (for example, tetracycline and quinolone antibiotics), which may reduce the effect of these drugs. To avoid this interaction, take Macrovit® and antibacterial drugs 2-3 hours apart. Avoid taking the drug if you are taking sulfonamides to avoid crystalluria.
Contraindications
A contraindication to the use of the drug is hypersensitivity to its components.
Compound
One capsule contains: beta-carotene in the form of a 30% suspension in oil - 6 mg, alpha-tocopheryl acetate - 15 mg, ascorbic acid - 75 mg. Excipients: refined sunflower oil, beeswax, lecithin. Composition of the capsule shell: gelatin, glycerin, purified water, methyl parahydroxybenzoate E-218, propyl parahydroxybenzoate E-216, titanium dioxide E-171, dye: charming red E-129.
Overdose
If the dosage instructions are followed, even with long-term use of the drug, overdose phenomena are not observed. If the daily norm is exceeded after taking Antioxycaps, nonspecific side effects are possible in the form of nausea, diarrhea, redness of the skin and other symptoms that disappear when the drug is discontinued.
Side effect
When using the drug in recommended doses, no side effects are observed. With prolonged use of high doses, allergic reactions are possible.
Storage conditions
Store in a place protected from moisture and light at a temperature of 15°C to 25°C. Store out of the reach of children.
Buy Macrovit tablet p/o in blister pack. in pack No. 10x3 in the pharmacy
Price for Makrovit tablet p/o in blister. in pack №10x3
Instructions for use for Macrovit tablet p/o in blister pack. in pack №10x3
Indications for use
The medication allows you to compensate for the lack of vitamins in special conditions:
- intense sports activities;
- increased mental/physical stress;
- breast-feeding;
- unbalanced/irregular diet in people with nicotine/alcohol addiction, with decreased appetite in the elderly group of patients, when following a diet, seasonal lack of fresh fruits and vegetables;
- carrying a pregnancy .
Overdose of the drug Makrovit, symptoms and treatment
Long-term use of the drug in high doses can cause hypervitaminosis A and D, although the likelihood of overdose is minimal. An overdose of vitamin D causes weakness, anorexia, nausea, vomiting, diarrhea, weight loss, fever, and convulsions. An overdose of vitamin A can lead to headaches, dizziness, sleep disturbances, nausea, vomiting, drowsiness, photophobia and seizures. If the above symptoms appear, you should stop taking the drug and carry out symptomatic treatment.
special instructions
It is allowed to prescribe a vitamin complex to children under 14 years of age at the discretion of the attending physician. It is unacceptable to independently change the dosage regimen.
The medication contains the azo dye E110 , which can provoke hypersensitivity reactions with asthmatic manifestations . Most often, such reactions are recorded in individuals with a history acetylsalicylic acid
During treatment, urine may temporarily take on an amber tint, which is a harmless manifestation of riboflavin being eliminated from the body.
The polyol contained in the composition can provoke diarrhea syndrome . For patients suffering from diabetes , consultation with an endocrinologist is recommended, because Each tablet contains glucose and sucrose, which may require adjustment of the main glucose-lowering therapy.
The adverse effect of the medication on the ability to operate complex machinery and drive a car has not been described.
Special instructions for the use of the drug Makrovit
patients with diabetes mellitus can use the drug, but it should be taken into account that each tablet contains 0.61 g of sucrose and 0.15 g of glucose, and the daily dose contains from 0.61 g to 1.8 g of sucrose and from 0.15 g up to 0.45 g of glucose. Before you start taking other vitamin preparations, minerals with vitamins and/or minerals in parallel, you should consult your doctor. During pregnancy and breastfeeding, you can take the drug only as recommended by your doctor. Does not affect the ability to drive vehicles or operate other mechanical equipment.
Analogs
Level 4 ATX code matches:
Tetravit
Decamevit
Aerovit
Gendevit
Sana-Sol
Hexavit
Revit
Vitasharm
Pikovit Forte
Pikovit
Vetoron for children
Vetoron E
Vetoron
Angiovitis
Undevit
Vitrum Performance
Pentovit
- Revit;
- Vitamult;
- Undevit;
- Vetoron;
- Gendevit;
- Multi-tabs;
- Pentovit;
- Neuromultivitis;
- Unigamma;
- Pikovit.
